Sonic Hedgehog-Gli1 signaling pathway might become an effective therapeutic target in gastrointestinal neuroendocrine carcinomas

Cancer Biology and Therapy

Volumn 5, Issue 11, 2006, Pages 1530-1538

  Shida, Takashi ^a   Furuya, Mitsuko ^a   Nikaido, Takashi ^b   Hasegawa, Masakazu ^a   Koda, Keiji ^a   Oda, Kenji ^a   Miyazaki, Masaru ^a   Kishimoto, Takashi ^a   Nakatani, Yukio ^a   Ishikura, Hiroshi ^a  

^a CHIBA UNIVERSITY   (Japan)

^b JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Cyclopamine; Gastrointestinal tract; Gli1; Hedgehog; Immunohistochemistry; Neuroendocrine carcinoma; Real time RT PCR

Indexed keywords

ALKALOID; CYCLOPAMINE; MESSENGER RNA; PARAFFIN; PROTEIN PATCHED 1; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN;

ADULT; AGED; APOPTOSIS; ARTICLE; CARCINOID; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GASTROINTESTINAL CARCINOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MITOSIS INHIBITION; NEUROENDOCRINE TUMOR; PATHOPHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR CELL; UPREGULATION;

EID: 33846998990     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.5.11.3458     Document Type: Article

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