-
1
-
-
15544384004
-
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters
-
Gamba, G. (2005) Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters. Physiol. Rev. 85, 423-493
-
(2005)
Physiol. Rev
, vol.85
, pp. 423-493
-
-
Gamba, G.1
-
2
-
-
0036193948
-
Human and murine phenotypes associated with defects in cation-chloride cotransport
-
Delpire, E. and Mount, D. B. (2002) Human and murine phenotypes associated with defects in cation-chloride cotransport. Annu. Rev. Physiol. 64, 803-843
-
(2002)
Annu. Rev. Physiol
, vol.64
, pp. 803-843
-
-
Delpire, E.1
Mount, D.B.2
-
3
-
-
33644938234
-
Ste20-type kinases: Evolutionarily conserved regulators of ion transport and cell volume
-
Strange, K., Denton, J. and Nehrke, K. (2006) Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume. Physiology 21, 61-68
-
(2006)
Physiology
, vol.21
, pp. 61-68
-
-
Strange, K.1
Denton, J.2
Nehrke, K.3
-
4
-
-
33744820299
-
SPAK and OSR1, key kinases involved in the regulation of chloride transport
-
Delpire, E. and Gagnon, K. B. (2006) SPAK and OSR1, key kinases involved in the regulation of chloride transport. Acta Physiol. 187, 103-113
-
(2006)
Acta Physiol
, vol.187
, pp. 103-113
-
-
Delpire, E.1
Gagnon, K.B.2
-
5
-
-
0034595634
-
WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II
-
Xu, B. E., English, J. M., Wilsbacher, J. L., Stippec, S., Goldsmith, E. J. and Cobb, M. H. (2000) WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II. J. Biol. Chem. 275, 16795-16801
-
(2000)
J. Biol. Chem
, vol.275
, pp. 16795-16801
-
-
Xu, B.E.1
English, J.M.2
Wilsbacher, J.L.3
Stippec, S.4
Goldsmith, E.J.5
Cobb, M.H.6
-
6
-
-
22844441657
-
Properties of WNK1 and implications for other family members
-
Lenertz, L. Y., Lee, B. H., Min, X. et al. (2005) Properties of WNK1 and implications for other family members. J. Biol. Chem. 280, 26653-26658
-
(2005)
J. Biol. Chem
, vol.280
, pp. 26653-26658
-
-
Lenertz, L.Y.1
Lee, B.H.2
Min, X.3
-
7
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
Wilson, F. H., Disse-Nicodème, S., Choate, K. A. et al. (2001) Human hypertension caused by mutations in WNK kinases. Science 293, 1107-1112
-
(2001)
Science
, vol.293
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicodème, S.2
Choate, K.A.3
-
8
-
-
0035936780
-
Molecular mechanisms of human hypertension
-
Lifton, R. P., Gharavi, A. G. and Geller, D. S. (2001) Molecular mechanisms of human hypertension. Cell 104, 545-556
-
(2001)
Cell
, vol.104
, pp. 545-556
-
-
Lifton, R.P.1
Gharavi, A.G.2
Geller, D.S.3
-
9
-
-
1842612033
-
Genetics of essential hypertension
-
Mein, C. A., Caulfield, M. J., Dobson, R. J. and Munroe, P. B. (2004) Genetics of essential hypertension. Hum. Mol. Genet. 13, R169-R175
-
(2004)
Hum. Mol. Genet
, vol.13
-
-
Mein, C.A.1
Caulfield, M.J.2
Dobson, R.J.3
Munroe, P.B.4
-
10
-
-
0038375052
-
Genome-wide mapping of human loci for essential hypertension
-
Caulfield, M., Munroe, P., Pembroke, J. et al. (2003) Genome-wide mapping of human loci for essential hypertension. Lancet 361, 2118-2123
-
(2003)
Lancet
, vol.361
, pp. 2118-2123
-
-
Caulfield, M.1
Munroe, P.2
Pembroke, J.3
-
11
-
-
0033963206
-
Mammalian distal tubule: Physiology, pathophysiology, and molecular anatomy
-
Reilly, R. F. and Ellison, D. H. (2000) Mammalian distal tubule: physiology, pathophysiology, and molecular anatomy. Physiol. Rev. 80, 277-313
-
(2000)
Physiol. Rev
, vol.80
, pp. 277-313
-
-
Reilly, R.F.1
Ellison, D.H.2
-
12
-
-
0018652407
-
The behaviour of transporting epithelial cells. I. Computer analysis of a basic model
-
Lew, V. L., Ferreira, H. G. and Moura, T. (1979) The behaviour of transporting epithelial cells. I. Computer analysis of a basic model. Proc. R. Soc. Lond. Ser. B 206, 53-83
-
(1979)
Proc. R. Soc. Lond. Ser. B
, vol.206
, pp. 53-83
-
-
Lew, V.L.1
Ferreira, H.G.2
Moura, T.3
-
13
-
-
1242295174
-
Molecular physiology of cation-coupled Cl-cotransport: The SLC12 family
-
Hebert, S. C., Mount, D. B. and Gamba, G. (2004) Molecular physiology of cation-coupled Cl-cotransport: the SLC12 family. Pflugers Arch. 447, 580-593
-
(2004)
Pflugers Arch
, vol.447
, pp. 580-593
-
-
Hebert, S.C.1
Mount, D.B.2
Gamba, G.3
-
14
-
-
10444275509
-
Recent insights into the structure and mechanism of the sodium pump
-
Horisberger, J.-D. (2004) Recent insights into the structure and mechanism of the sodium pump. Physiology 19, 377-387
-
(2004)
Physiology
, vol.19
, pp. 377-387
-
-
Horisberger, J.-D.1
-
15
-
-
0038621773
-
Structure and mechanism of Na,K-ATPase: Functional sites and their interactions
-
Jorgensen, P. L., Hakansson, K. O. and Karlish, S. J. D. (2003) Structure and mechanism of Na,K-ATPase: Functional sites and their interactions. Annu. Rev. Physiol. 65, 817-849
-
(2003)
Annu. Rev. Physiol
, vol.65
, pp. 817-849
-
-
Jorgensen, P.L.1
Hakansson, K.O.2
Karlish, S.J.D.3
-
16
-
-
33645984859
-
Role of FXYD proteins in ion transport
-
Garty, H. and Karlish, S. J. D. (2006) Role of FXYD proteins in ion transport. Annu. Rev. Physiol. 68, 431-459
-
(2006)
Annu. Rev. Physiol
, vol.68
, pp. 431-459
-
-
Garty, H.1
Karlish, S.J.D.2
-
17
-
-
28244497641
-
Sodium pump α2 subunits control myogenic tone and blood pressure in mice
-
Zhang, J., Lee, M. Y., Cavalli, M. et al. (2005) Sodium pump α2 subunits control myogenic tone and blood pressure in mice. J. Physiol. 569, 243-256
-
(2005)
J. Physiol
, vol.569
, pp. 243-256
-
-
Zhang, J.1
Lee, M.Y.2
Cavalli, M.3
-
18
-
-
33745427978
-
Localization of the ROMK protein on apical membranes of rat kidney nephron segments
-
Xu, J. Z., Hall, A. E., Peterson, L. N., Bienkowski, M. J., Eessalu, T. E. and Hebert, S. C. (1997) Localization of the ROMK protein on apical membranes of rat kidney nephron segments. Am. J. Physiol. 273, F739-F748
-
(1997)
Am. J. Physiol
, vol.273
-
-
Xu, J.Z.1
Hall, A.E.2
Peterson, L.N.3
Bienkowski, M.J.4
Eessalu, T.E.5
Hebert, S.C.6
-
19
-
-
0031711390
-
Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism
-
Hebert, S. C. (1998) Roles of Na-K-2Cl and Na-Cl cotransporters and ROMK potassium channels in urinary concentrating mechanism. Am. J. Physiol. 275, F325-F327
-
(1998)
Am. J. Physiol
, vol.275
-
-
Hebert, S.C.1
-
20
-
-
0028812435
-
+ channel. II. Cloning and distribution of alternative forms
-
+ channel. II. Cloning and distribution of alternative forms. Am. J. Physiol. 268, F1132-F1140
-
(1995)
Am. J. Physiol
, vol.268
-
-
Boim, M.A.1
Ho, K.2
Shuck, M.E.3
-
21
-
-
12944294332
-
Molecular diversity and regulation of renal potassium channels
-
Hebert, S. C., Desir, G., Giebisch, G. and Wang, W. (2005) Molecular diversity and regulation of renal potassium channels. Physiol. Rev. 85, 319-371
-
(2005)
Physiol. Rev
, vol.85
, pp. 319-371
-
-
Hebert, S.C.1
Desir, G.2
Giebisch, G.3
Wang, W.4
-
22
-
-
15544390386
-
Function of chloride channels in the kidney
-
Uchida, S. and Sasaki, S. (2005) Function of chloride channels in the kidney. Annu. Rev. Physiol. 67, 759-778
-
(2005)
Annu. Rev. Physiol
, vol.67
, pp. 759-778
-
-
Uchida, S.1
Sasaki, S.2
-
23
-
-
0035189356
-
Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure
-
Birkenhäger, R., Otto, E., Schürmann, M. J. et al. (2001) Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failure. Nat. Genet. 29, 310-314
-
(2001)
Nat. Genet
, vol.29
, pp. 310-314
-
-
Birkenhäger, R.1
Otto, E.2
Schürmann, M.J.3
-
24
-
-
0030707887
-
Renal magnesium handling: New insights in understanding old problems
-
Quamme, G. A. (1997) Renal magnesium handling: new insights in understanding old problems. Kidney Int. 52, 1180-1195
-
(1997)
Kidney Int
, vol.52
, pp. 1180-1195
-
-
Quamme, G.A.1
-
25
-
-
0033695807
-
Divalent cation transport by the distal nephron: Insights from Bartter's and Gitelman's syndromes
-
Ellison, D. H. (2000) Divalent cation transport by the distal nephron: insights from Bartter's and Gitelman's syndromes. Am. J. Physiol. Renal Physiol. 279, F616-F625
-
(2000)
Am. J. Physiol. Renal Physiol
, vol.279
-
-
Ellison, D.H.1
-
26
-
-
33645963995
-
Claudins and epithelial paracellular transport
-
Van Itallie, C. M. and Anderson, J. M. (2006) Claudins and epithelial paracellular transport. Annu. Rev. Physiol. 68, 403-429
-
(2006)
Annu. Rev. Physiol
, vol.68
, pp. 403-429
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
27
-
-
0035139184
-
Magnesium transport in the renal distal convoluted tubule
-
Dai, L.-J., Ritchie, G., Kerstan, D., Kang, H. S., Cole, D. E. C. and Quamme, G. A. (2001) Magnesium transport in the renal distal convoluted tubule. Physiol. Rev. 81, 51-84
-
(2001)
Physiol. Rev
, vol.81
, pp. 51-84
-
-
Dai, L.-J.1
Ritchie, G.2
Kerstan, D.3
Kang, H.S.4
Cole, D.E.C.5
Quamme, G.A.6
-
28
-
-
0028296720
-
Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney
-
Payne, J. A. and Forbush, III, B. (1994) Alternatively spliced isoforms of the putative renal Na-K-Cl cotransporter are differentially distributed within the rabbit kidney. Proc. Natl Acad. Sci. U.S.A. 91, 4544-4548
-
(1994)
Proc. Natl Acad. Sci. U.S.A
, vol.91
, pp. 4544-4548
-
-
Payne, J.A.1
Forbush III, B.2
-
29
-
-
0028833225
-
Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter
-
Igarashi, P., Vanden Heuvel, G. B., Payne, J. A. and Forbush, III, B. (1995) Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am. J. Physiol. 269, F405-F418
-
(1995)
Am. J. Physiol
, vol.269
-
-
Igarashi, P.1
Vanden Heuvel, G.B.2
Payne, J.A.3
Forbush III, B.4
-
30
-
-
0037088671
-
Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions
-
Giménez, I., Isenring, P. and Forbush, B. (2002) Spatially distributed alternative splice variants of the renal Na-K-Cl cotransporter exhibit dramatically different affinities for the transported ions. J. Biol. Chem. 277, 8767-8770
-
(2002)
J. Biol. Chem
, vol.277
, pp. 8767-8770
-
-
Giménez, I.1
Isenring, P.2
Forbush, B.3
-
32
-
-
0032944986
-
Isoforms of the Na-K-2Cl cotransporter in murine TAL I. Molecular characterization and intrarenal localization
-
Mount, D. B., Baekgaard, A., Hall, A. E. et al. (1999) Isoforms of the Na-K-2Cl cotransporter in murine TAL I. Molecular characterization and intrarenal localization. Am. J. Physiol. 276, F347-F358
-
(1999)
Am. J. Physiol
, vol.276
-
-
Mount, D.B.1
Baekgaard, A.2
Hall, A.E.3
-
33
-
-
0033854727
-
The Na-K-Cl cotransporter of secretory epithelia
-
Haas, M. and Forbush, III, B. (2000) The Na-K-Cl cotransporter of secretory epithelia. Annu. Rev. Physiol. 62, 515-534
-
(2000)
Annu. Rev. Physiol
, vol.62
, pp. 515-534
-
-
Haas, M.1
Forbush III, B.2
-
34
-
-
0033968208
-
Sodium-potassium-chloride cotransport
-
Russell, J. M. (2000) Sodium-potassium-chloride cotransport. Physiol. Rev. 80, 211-276
-
(2000)
Physiol. Rev
, vol.80
, pp. 211-276
-
-
Russell, J.M.1
-
35
-
-
0026465685
-
The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation
-
Lytle, C. and Forbush, III, B. (1992) The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation. J. Biol. Chem. 267, 25438-25443
-
(1992)
J. Biol. Chem
, vol.267
, pp. 25438-25443
-
-
Lytle, C.1
Forbush III, B.2
-
36
-
-
0031006262
-
Activation of the avian erythrocyte Na-K-Cl cotransport protein by cell shrinkage, cAMP, fluoride, and calyculin-A involves phosphorylation at common sites
-
Lytle, C. (1997) Activation of the avian erythrocyte Na-K-Cl cotransport protein by cell shrinkage, cAMP, fluoride, and calyculin-A involves phosphorylation at common sites. J. Biol. Chem. 272, 15069-15077
-
(1997)
J. Biol. Chem
, vol.272
, pp. 15069-15077
-
-
Lytle, C.1
-
37
-
-
0037020145
-
A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1
-
Darman, R. B. and Forbush, B. (2002) A regulatory locus of phosphorylation in the N terminus of the Na-K-Cl cotransporter, NKCC1. J. Biol. Chem. 277, 37542-37550
-
(2002)
J. Biol. Chem
, vol.277
, pp. 37542-37550
-
-
Darman, R.B.1
Forbush, B.2
-
38
-
-
0037020095
-
Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody
-
Flemmer, A. W., Giménez, I., Dowd, B. F. X., Darman, R. B. and Forbush, B. (2002) Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody. J. Biol. Chem. 277, 37551-37558
-
(2002)
J. Biol. Chem
, vol.277
, pp. 37551-37558
-
-
Flemmer, A.W.1
Giménez, I.2
Dowd, B.F.X.3
Darman, R.B.4
Forbush, B.5
-
39
-
-
0038035205
-
Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein
-
Giménez, I. and Forbush, B. (2003) Short-term stimulation of the renal Na-K-Cl cotransporter (NKCC2) by vasopressin involves phosphorylation and membrane translocation of the protein. J. Biol. Chem. 278, 26946-26951
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26946-26951
-
-
Giménez, I.1
Forbush, B.2
-
41
-
-
0035860734
-
Modulation of ion transport by direct targeting of protein phosphatase type I to the Na-K-Cl cotransporter
-
Darman, R. B., Flemmer, A. and Forbush, B. (2001) Modulation of ion transport by direct targeting of protein phosphatase type I to the Na-K-Cl cotransporter. J. Biol. Chem. 276, 34359-34362
-
(2001)
J. Biol. Chem
, vol.276
, pp. 34359-34362
-
-
Darman, R.B.1
Flemmer, A.2
Forbush, B.3
-
42
-
-
0032860980
-
JNK is a volume-sensitive kinase that phosphorylates the Na-K-2Cl cotransporter in vitro
-
Klein, J. D., Lamitina, S. T. and O'Neill, W. C. (1999) JNK is a volume-sensitive kinase that phosphorylates the Na-K-2Cl cotransporter in vitro. Am. J. Physiol. 277, C425-C431
-
(1999)
Am. J. Physiol
, vol.277
-
-
Klein, J.D.1
Lamitina, S.T.2
O'Neill, W.C.3
-
43
-
-
0034608794
-
Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy
-
Lang, F., Klingel, K., Wagner, C. A. et al. (2000) Deranged transcriptional regulation of cell-volume-sensitive kinase hSGK in diabetic nephropathy. Proc. Natl. Acad. Sci. U.S.A. 97, 8157-8162
-
(2000)
Proc. Natl. Acad. Sci. U.S.A
, vol.97
, pp. 8157-8162
-
-
Lang, F.1
Klingel, K.2
Wagner, C.A.3
-
44
-
-
0037073286
-
Regulation of Na-K-2Cl cotransport by phosphorylation and protein-protein interactions
-
Flatman, P. W. (2002) Regulation of Na-K-2Cl cotransport by phosphorylation and protein-protein interactions. Biochim. Biophys. Acta 1566, 140-151
-
(2002)
Biochim. Biophys. Acta
, vol.1566
, pp. 140-151
-
-
Flatman, P.W.1
-
45
-
-
22844434858
-
Regulation of erythrocyte Na-K-2Cl cotransport by threonine phosphorylation
-
Matskevich, I., Hegney, K. L. and Flatman, P. W. (2005) Regulation of erythrocyte Na-K-2Cl cotransport by threonine phosphorylation. Biochim. Biophys. Acta 1714, 25-34
-
(2005)
Biochim. Biophys. Acta
, vol.1714
, pp. 25-34
-
-
Matskevich, I.1
Hegney, K.L.2
Flatman, P.W.3
-
46
-
-
0037184942
-
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
-
Piechotta, K., Lu, J. and Delpire, E. (2002) Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J. Biol. Chem. 277, 50812-50819
-
(2002)
J. Biol. Chem
, vol.277
, pp. 50812-50819
-
-
Piechotta, K.1
Lu, J.2
Delpire, E.3
-
48
-
-
0042847432
-
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
-
Dowd, B. F. X. and Forbush, B. (2003) PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J. Biol. Chem. 278, 27347-27353
-
(2003)
J. Biol. Chem
, vol.278
, pp. 27347-27353
-
-
Dowd, B.F.X.1
Forbush, B.2
-
49
-
-
33745530924
-
Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1
-
Vitari, A. C., Thastrup, J., Rafiqi, F. et al. (2006) Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1. Biochem. J. 397, 223-231
-
(2006)
Biochem. J
, vol.397
, pp. 223-231
-
-
Vitari, A.C.1
Thastrup, J.2
Rafiqi, F.3
-
50
-
-
0034737808
-
Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses
-
Tsutsumi, T., Ushiro, H., Kosaka, T., Kayahara, T. and Nakano, K. (2000) Proline- and alanine-rich Ste20-related kinase associates with F-actin and translocates from the cytosol to cytoskeleton upon cellular stresses. J. Biol. Chem. 275, 9157-9162
-
(2000)
J. Biol. Chem
, vol.275
, pp. 9157-9162
-
-
Tsutsumi, T.1
Ushiro, H.2
Kosaka, T.3
Kayahara, T.4
Nakano, K.5
-
51
-
-
30044442784
-
WNK1 Regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1
-
Moriguchi, T., Urushiyama, S., Hisamoto, N. et al. (2005) WNK1 Regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. J. Biol. Chem. 280, 42685-42693
-
(2005)
J. Biol. Chem
, vol.280
, pp. 42685-42693
-
-
Moriguchi, T.1
Urushiyama, S.2
Hisamoto, N.3
-
52
-
-
30644472724
-
Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter
-
Gagnon, K. B. E., England, R. and Delpire, E. (2006) Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter. Mol. Cell. Biol. 26, 689-698
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 689-698
-
-
Gagnon, K.B.E.1
England, R.2
Delpire, E.3
-
53
-
-
30644458584
-
- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4
-
- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4. Am. J. Physiol. Cell Physiol. 290, C134-C142
-
(2006)
Am. J. Physiol. Cell Physiol
, vol.290
-
-
Gagnon, K.B.E.1
England, R.2
Delpire, E.3
-
54
-
-
26844532768
-
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
-
Vitari, A. C., Deak, M., Morrice, N. A. and Alessi, D. R. (2005) The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases. Biochem. J. 391, 17-24
-
(2005)
Biochem. J
, vol.391
, pp. 17-24
-
-
Vitari, A.C.1
Deak, M.2
Morrice, N.A.3
Alessi, D.R.4
-
55
-
-
14944384544
-
- cotransport by deoxygenation
-
- cotransport by deoxygenation. J. Physiol. 563, 421-431
-
(2005)
J. Physiol
, vol.563
, pp. 421-431
-
-
Flatman, P.W.1
-
56
-
-
0033560346
-
Genetic disorders of renal electrolyte transport
-
Scheinman, S. J., Guay-Woodford, L. M., Thakker, R. V. and Warnock, D. G. (1999) Genetic disorders of renal electrolyte transport. N. Engl. J. Med. 340, 1177-1187
-
(1999)
N. Engl. J. Med
, vol.340
, pp. 1177-1187
-
-
Scheinman, S.J.1
Guay-Woodford, L.M.2
Thakker, R.V.3
Warnock, D.G.4
-
57
-
-
0029189663
-
Expression of the thiazide-sensitive Na-Cl cotransporter in rat and human kidney
-
Obermüller, N., Bernstein, P., Velázquez, H. et al. (1995) Expression of the thiazide-sensitive Na-Cl cotransporter in rat and human kidney. Am. J. Physiol. 269, F900-F910
-
(1995)
Am. J. Physiol
, vol.269
-
-
Obermüller, N.1
Bernstein, P.2
Velázquez, H.3
-
58
-
-
0027405688
-
Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter
-
Gamba, G., Saltzberg, S. N., Lombardi, M. et al. (1993) Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc. Natl Acad. Sci. U.S.A. 90, 2749-2753
-
(1993)
Proc. Natl Acad. Sci. U.S.A
, vol.90
, pp. 2749-2753
-
-
Gamba, G.1
Saltzberg, S.N.2
Lombardi, M.3
-
59
-
-
0036086609
-
Functional differences between flounder and rat thiazide-sensitive Na-Cl cotransporter
-
Vázquez, N., Monroy, A., Dorantes, E., Muñoz-Clares, R. A. and Gamba, G. (2002) Functional differences between flounder and rat thiazide-sensitive Na-Cl cotransporter. Am. J. Physiol. Renal Physiol. 282, F599-F607
-
(2002)
Am. J. Physiol. Renal Physiol
, vol.282
-
-
Vázquez, N.1
Monroy, A.2
Dorantes, E.3
Muñoz-Clares, R.A.4
Gamba, G.5
-
61
-
-
0032698959
-
Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome
-
Kunchaparty, S., Palcso, M., Berkman, J. et al. (1999) Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome. Am. J. Physiol. 277, F643-F649
-
(1999)
Am. J. Physiol
, vol.277
-
-
Kunchaparty, S.1
Palcso, M.2
Berkman, J.3
-
62
-
-
0036014925
-
Functional expression of mutations in the human NaCl cotransporter: Evidence for impaired routing mechanisms in Gitelman's syndrome
-
de Jong, J. C., van der Vliet, W. A., van den Heuvel, L. P. W. J., Willems, P. H. G. M., Knoers, N. V. A. M. and Bindels, R. J. M. (2002) Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome. J. Am. Soc. Nephrol. 13, 1442-1448
-
(2002)
J. Am. Soc. Nephrol
, vol.13
, pp. 1442-1448
-
-
de Jong, J.C.1
van der Vliet, W.A.2
van den Heuvel, L.P.W.J.3
Willems, P.H.G.M.4
Knoers, N.V.A.M.5
Bindels, R.J.M.6
-
63
-
-
0042591321
-
The structural unit of the thiazide-sensitive NaCl cotransporter is a homodimer
-
de Jong, J. C., Willems, P. H. G. M., Mooren, F. J. M., van den Heuvel, L. P. W. J., Knoers, N. V. A. M. and Bindels, R. J. M. (2003) The structural unit of the thiazide-sensitive NaCl cotransporter is a homodimer. J. Biol. Chem. 278, 24302-24307
-
(2003)
J. Biol. Chem
, vol.278
, pp. 24302-24307
-
-
de Jong, J.C.1
Willems, P.H.G.M.2
Mooren, F.J.M.3
van den Heuvel, L.P.W.J.4
Knoers, N.V.A.M.5
Bindels, R.J.M.6
-
64
-
-
0141566892
-
Functional expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby canine kidney cells
-
de Jong, J. C., Willems, P. H. G. M., van den Heuvel, L. P. W. J., Knoers, N. V. A. M. and Bindels, R. J. M. (2003) Functional expression of the human thiazide-sensitive NaCl cotransporter in Madin-Darby canine kidney cells. J. Am. Soc. Nephrol. 14, 2428-2435
-
(2003)
J. Am. Soc. Nephrol
, vol.14
, pp. 2428-2435
-
-
de Jong, J.C.1
Willems, P.H.G.M.2
van den Heuvel, L.P.W.J.3
Knoers, N.V.A.M.4
Bindels, R.J.M.5
-
65
-
-
33745076253
-
WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells
-
Cai, H., Cebotaru, V., Wang, J. H. et al. (2006) WNK4 kinase regulates surface expression of the human sodium chloride cotransporter in mammalian cells. Kidney Int. 69, 2162-2170
-
(2006)
Kidney Int
, vol.69
, pp. 2162-2170
-
-
Cai, H.1
Cebotaru, V.2
Wang, J.H.3
-
66
-
-
15944412561
-
Regulation of diverse ion transport pathways by WNK4 kinase: A novel molecular switch
-
Kahle, K. T., Wilson, F. H. and Lifton, R. P. (2005) Regulation of diverse ion transport pathways by WNK4 kinase: a novel molecular switch. Trends Endocrinol. Metab. 16, 98-103
-
(2005)
Trends Endocrinol. Metab
, vol.16
, pp. 98-103
-
-
Kahle, K.T.1
Wilson, F.H.2
Lifton, R.P.3
-
67
-
-
12144272609
-
Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension
-
Gamba, G. (2005) Role of WNK kinases in regulating tubular salt and potassium transport and in the development of hypertension. Am. J. Physiol. Renal Physiol. 288, F245-F252
-
(2005)
Am. J. Physiol. Renal Physiol
, vol.288
-
-
Gamba, G.1
-
68
-
-
0035817725
-
WNK kinases, a novel protein kinase subfamily in multi-cellular organisms
-
Veríssimo, F. and Jordan, P. (2001) WNK kinases, a novel protein kinase subfamily in multi-cellular organisms. Oncogene 20, 5562-5569
-
(2001)
Oncogene
, vol.20
, pp. 5562-5569
-
-
Veríssimo, F.1
Jordan, P.2
-
69
-
-
0037382807
-
WNK kinases regulate thiazide-sensitive Na-Cl cotransport
-
Yang, C. L., Angell, J., Mitchell, R. and Ellison, D. H. (2003) WNK kinases regulate thiazide-sensitive Na-Cl cotransport. J. Clin. Invest. 111, 1039-1045
-
(2003)
J. Clin. Invest
, vol.111
, pp. 1039-1045
-
-
Yang, C.L.1
Angell, J.2
Mitchell, R.3
Ellison, D.H.4
-
70
-
-
0037457965
-
Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4
-
Wilson, F. H., Kahle, K. T., Sabath, E. et al. (2003) Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4. Proc. Natl Acad. Sci. U.S.A. 100, 680-684
-
(2003)
Proc. Natl Acad. Sci. U.S.A
, vol.100
, pp. 680-684
-
-
Wilson, F.H.1
Kahle, K.T.2
Sabath, E.3
-
71
-
-
18244373189
-
Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport
-
Yang, C. L., Zhu, X., Wang, Z., Subramanya, A. R. and Ellison, D. H. (2005) Mechanisms of WNK1 and WNK4 interaction in the regulation of thiazide-sensitive NaCl cotransport. J. Clin. Invest. 115, 1379-1387
-
(2005)
J. Clin. Invest
, vol.115
, pp. 1379-1387
-
-
Yang, C.L.1
Zhu, X.2
Wang, Z.3
Subramanya, A.R.4
Ellison, D.H.5
-
72
-
-
33744811449
-
WNK1 kinase isoform switch regulates renal potassium excretion
-
Wade, J. B., Fang, L., Liu, J. et al. (2006) WNK1 kinase isoform switch regulates renal potassium excretion. Proc. Natl Acad. Sci. U.S.A. 103, 8558-8563
-
(2006)
Proc. Natl Acad. Sci. U.S.A
, vol.103
, pp. 8558-8563
-
-
Wade, J.B.1
Fang, L.2
Liu, J.3
-
73
-
-
33645557214
-
Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform
-
Subramanya, A. R., Yang, C. L., Zhu, X. and Ellison, D. H. (2006) Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform. Am. J. Physiol. Renal Physiol. 290, F619-F624
-
(2006)
Am. J. Physiol. Renal Physiol
, vol.290
-
-
Subramanya, A.R.1
Yang, C.L.2
Zhu, X.3
Ellison, D.H.4
-
74
-
-
33645581195
-
WNK signaling in the distal tubule: An inhibitory cascade regulating salt transport
-
Yu, A. S. L. (2006) WNK signaling in the distal tubule: an inhibitory cascade regulating salt transport. Am. J. Physiol. Renal Physiol. 290, F617-F618
-
(2006)
Am. J. Physiol. Renal Physiol
, vol.290
-
-
Yu, A.S.L.1
-
76
-
-
11144354175
-
Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins
-
Yamauchi, K., Rai, T., Kobayashi, K. et al. (2004) Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins. Proc. Natl Acad. Sci. U.S.A. 101, 4690-4694
-
(2004)
Proc. Natl Acad. Sci. U.S.A
, vol.101
, pp. 4690-4694
-
-
Yamauchi, K.1
Rai, T.2
Kobayashi, K.3
-
79
-
-
1842689693
-
Comparison of WNK4 and WNK1 kinase and inhibiting activities
-
Wang, Z., Yang, C. L. and Ellison, D. H. (2004) Comparison of WNK4 and WNK1 kinase and inhibiting activities. Biochem. Biophys. Res. Commun. 317, 939-944
-
(2004)
Biochem. Biophys. Res. Commun
, vol.317
, pp. 939-944
-
-
Wang, Z.1
Yang, C.L.2
Ellison, D.H.3
-
80
-
-
4444327825
-
WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding
-
Lee, B. H., Min, X., Heise, C. J. et al. (2004) WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding. Mol. Cell. 15, 741-751
-
(2004)
Mol. Cell
, vol.15
, pp. 741-751
-
-
Lee, B.H.1
Min, X.2
Heise, C.J.3
-
81
-
-
33744804812
-
WNK kinases influence TRPV4 channel function and localization
-
Fu, Y., Subramanya, A., Rozansky, D. and Cohen, D. M. (2006) WNK kinases influence TRPV4 channel function and localization. Am. J. Physiol. Renal Physiol. 290, F1305-F1314
-
(2006)
Am. J. Physiol. Renal Physiol
, vol.290
-
-
Fu, Y.1
Subramanya, A.2
Rozansky, D.3
Cohen, D.M.4
-
82
-
-
31944441600
-
Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms
-
Lazrak, A., Liu, Z. and Huang, C. L. (2006) Antagonistic regulation of ROMK by long and kidney-specific WNK1 isoforms. Proc. Natl Acad. Sci. U.S.A. 103, 1615-1620
-
(2006)
Proc. Natl Acad. Sci. U.S.A
, vol.103
, pp. 1615-1620
-
-
Lazrak, A.1
Liu, Z.2
Huang, C.L.3
-
83
-
-
33745811310
-
WNK1 affects surface expression of the ROMK potassium channel independent of WNK4
-
Cope, G., Murthy, M., Golbang, A. P. et al. (2006) WNK1 affects surface expression of the ROMK potassium channel independent of WNK4. J. Am. Soc. Nephrol. 17, 1867-1874
-
(2006)
J. Am. Soc. Nephrol
, vol.17
, pp. 1867-1874
-
-
Cope, G.1
Murthy, M.2
Golbang, A.P.3
-
84
-
-
33746058616
-
Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway
-
Veríssimo, F., Silva, E., Morris, J. D., Pepperkok, R. and Jordan, P. (2006) Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway. Oncogene 25, 4172-4182
-
(2006)
Oncogene
, vol.25
, pp. 4172-4182
-
-
Veríssimo, F.1
Silva, E.2
Morris, J.D.3
Pepperkok, R.4
Jordan, P.5
-
85
-
-
28044458544
-
-
- cotransporters required for normal blood pressure homeostasis. Proc. Natl Acad. Sci. U.S.A. 102, 16777-16782
-
- cotransporters required for normal blood pressure homeostasis. Proc. Natl Acad. Sci. U.S.A. 102, 16777-16782
-
-
-
-
86
-
-
28044473649
-
-
- in and out of cells: Implications for control of cell and neuronal excitability. Proc. Natl Acad. Sci. U.S.A. 102, 16783-16788
-
- in and out of cells: Implications for control of cell volume and neuronal excitability. Proc. Natl Acad. Sci. U.S.A. 102, 16783-16788
-
-
-
-
87
-
-
32444437942
-
-
de los Heros, P., Kahle, K. T., Rinehart, J. et al. (2006) WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. Proc. Natl Acad. Sci. U.S.A. 103, 1976-1981
-
de los Heros, P., Kahle, K. T., Rinehart, J. et al. (2006) WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway. Proc. Natl Acad. Sci. U.S.A. 103, 1976-1981
-
-
-
-
89
-
-
0029881331
-
Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: Modulation by cytoplasmic Cl
-
Lytle, C. and Forbush, III, B. (1996) Regulatory phosphorylation of the secretory Na-K-Cl cotransporter: modulation by cytoplasmic Cl. Am. J. Physiol. 270, C437-C448
-
(1996)
Am. J. Physiol
, vol.270
-
-
Lytle, C.1
Forbush III, B.2
-
90
-
-
15544364940
-
Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases
-
Meneton, P., Jeunemaitre, X., de Wardener, H. E. and Macgregor, G. A. (2005) Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases. Physiol. Rev. 85, 679-715
-
(2005)
Physiol. Rev
, vol.85
, pp. 679-715
-
-
Meneton, P.1
Jeunemaitre, X.2
de Wardener, H.E.3
Macgregor, G.A.4
-
91
-
-
33645849217
-
Hypertension, kidney, and transgenics: A fresh perspective
-
Mullins, L. J., Bailey, M. A. and Mullins, J. J. (2006) Hypertension, kidney, and transgenics: a fresh perspective. Physiol. Rev. 86, 709-746
-
(2006)
Physiol. Rev
, vol.86
, pp. 709-746
-
-
Mullins, L.J.1
Bailey, M.A.2
Mullins, J.J.3
-
93
-
-
21044457253
-
Renal tubular transport and the genetic basis of hypertensive disease
-
Lang, F., Capasso, G., Schwab, M. and Waldegger, S. (2005) Renal tubular transport and the genetic basis of hypertensive disease. Clin. Exp. Nephrol. 9, 91-99
-
(2005)
Clin. Exp. Nephrol
, vol.9
, pp. 91-99
-
-
Lang, F.1
Capasso, G.2
Schwab, M.3
Waldegger, S.4
-
94
-
-
0032895915
-
Genetic and biochemical determinants of abnormal monovalent ion transport in primary hypertension
-
Orlov, S. N., Adragna, N. C., Adarichev, V. A. and Hamet, P. (1999) Genetic and biochemical determinants of abnormal monovalent ion transport in primary hypertension. Am. J. Physiol. 276, C511-C536
-
(1999)
Am. J. Physiol
, vol.276
-
-
Orlov, S.N.1
Adragna, N.C.2
Adarichev, V.A.3
Hamet, P.4
-
95
-
-
26444443132
-
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study
-
Newhouse, S. J., Wallace, C., Dobson, R. et al. (2005) Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension study. Hum. Mol. Genet. 14, 1805-1814
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 1805-1814
-
-
Newhouse, S.J.1
Wallace, C.2
Dobson, R.3
-
96
-
-
33644874530
-
Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population
-
Tobin, M. D., Raleigh, S. M., Newhouse, S. et al. (2005) Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population. Circulation 112, 3423-3429
-
(2005)
Circulation
, vol.112
, pp. 3423-3429
-
-
Tobin, M.D.1
Raleigh, S.M.2
Newhouse, S.3
-
97
-
-
33644876156
-
Association of blood pressure with genetic variation in WNK kinases in a white european population
-
Zhang, H. and Staessen, J. A. (2005) Association of blood pressure with genetic variation in WNK kinases in a white european population. Circulation 112, 3371-3372
-
(2005)
Circulation
, vol.112
, pp. 3371-3372
-
-
Zhang, H.1
Staessen, J.A.2
-
98
-
-
10744226663
-
Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention
-
Zambrowicz, B. P., Abuin, A., Ramirez-Solis, R. et al. (2003) Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Proc. Natl Acad. Sci. U.S.A. 100, 14109-14114
-
(2003)
Proc. Natl Acad. Sci. U.S.A
, vol.100
, pp. 14109-14114
-
-
Zambrowicz, B.P.1
Abuin, A.2
Ramirez-Solis, R.3
-
100
-
-
33846963232
-
Hypertension
-
Bernhardt, I. and Ellory, J. C, eds, pp, Springer, Berlin
-
Orlov, S. N. (2004) Hypertension. In Red Cell Membranes in Health and Disease (Bernhardt, I. and Ellory, J. C., eds.), pp. 587-602, Springer, Berlin
-
(2004)
Red Cell Membranes in Health and Disease
, pp. 587-602
-
-
Orlov, S.N.1
-
102
-
-
0032437253
-
- co-transport measurement in essential hypertension: Useful diagnostic tools or failure? A meta-analysis of 17 years of literature
-
- co-transport measurement in essential hypertension: useful diagnostic tools or failure? A meta-analysis of 17 years of literature. Clin. Sci. 95, 649-657
-
(1998)
Clin. Sci
, vol.95
, pp. 649-657
-
-
Tepper, T.1
Sluiter, W.J.2
Huisman, R.M.3
de Zeeuw, D.4
-
103
-
-
2542446285
-
Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension
-
Jeck, N., Waldegger, S., Lampert, A. et al. (2004) Activating mutation of the renal epithelial chloride channel ClC-Kb predisposing to hypertension. Hypertension 43, 1175-1181
-
(2004)
Hypertension
, vol.43
, pp. 1175-1181
-
-
Jeck, N.1
Waldegger, S.2
Lampert, A.3
-
104
-
-
3042628538
-
A genetic predisposition to hypertension?
-
Geller, D. S. (2004) A genetic predisposition to hypertension? Hypertension 44, 27-28
-
(2004)
Hypertension
, vol.44
, pp. 27-28
-
-
Geller, D.S.1
-
105
-
-
0037421538
-
Role of magnesium in the pathogenesis of hypertension
-
Touyz, R. M. (2003) Role of magnesium in the pathogenesis of hypertension. Mol. Aspects Med. 24, 107-136
-
(2003)
Mol. Aspects Med
, vol.24
, pp. 107-136
-
-
Touyz, R.M.1
-
106
-
-
26844434013
-
2+ in the pathogenesis of hypertension
-
2+ in the pathogenesis of hypertension. Magnes. Res. 18, 175-185
-
(2005)
Magnes. Res
, vol.18
, pp. 175-185
-
-
Ebel, H.1
Günther, T.2
-
107
-
-
13444267278
-
Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells
-
He, Y., Yao, G., Savoia, C. and Touyz, R. M. (2005) Transient receptor potential melastatin 7 ion channels regulate magnesium homeostasis in vascular smooth muscle cells. Circ. Res. 96, 207-215
-
(2005)
Circ. Res
, vol.96
, pp. 207-215
-
-
He, Y.1
Yao, G.2
Savoia, C.3
Touyz, R.M.4
-
108
-
-
33644840378
-
Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats
-
Touyz, R. M., He, Y., Montezano, A. C. I. et al. (2006) Differential regulation of transient receptor potential melastatin 6 and 7 cation channels by ANG II in vascular smooth muscle cells from spontaneously hypertensive rats. Am. J. Physiol. Regulatory. Integrative Comp. Physiol. 290, R73-R78
-
(2006)
Am. J. Physiol. Regulatory. Integrative Comp. Physiol
, vol.290
-
-
Touyz, R.M.1
He, Y.2
Montezano, A.C.I.3
-
109
-
-
0345257781
-
A molecular switch controlling renal sodium and potassium excretion
-
Bindels, R. J. M. (2003) A molecular switch controlling renal sodium and potassium excretion. Nat. Genet. 35, 302-303
-
(2003)
Nat. Genet
, vol.35
, pp. 302-303
-
-
Bindels, R.J.M.1
|