Isoforms of the Na-K-2Cl cotransporter in murine TAL I. Molecular characterization and intrarenal localization

American Journal of Physiology - Renal Physiology

Volumn 276, Issue 3 45-3, 1999, Pages

  Mount, David B ^a,e   Baekgaard, Allan ^b   Hall, Amy E ^a   Plata, Consuelo ^c   Xu, Jason ^a   Beier, David R ^d   Gamba, Gerardo ^c   Hebert, Steven C ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e VANDERBILT UNIVERSITY   (United States)

Author keywords

Adenosine 3',5' cyclic monophosphate; Alternative splicing; Bumetanide; Protein kinase A; Sodium potassium chloride cotransporter; Thick ascending limb of Henle

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); BUMETANIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHLORIDE TRANSPORT; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; HENLE LOOP; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE EPITHELIUM; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; SODIUM TRANSPORT;

EID: 0032944986     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.1999.276.3.f347     Document Type: Article

References (34)

1. Allen, F., and C. C. Tisher. Morphology of the ascending thick limb of Henle. Kidney Int. 9: 8-22, 1976.
2. Altschul, S. F., T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25: 3389-3402, 1997.
3. + channel by its β- and γ- subunits. Am. J. Physiol. 273 (Cell Physiol. 42): C1889-C1899, 1997.
4. Beier, D. R. Single-strand conformation polymorphism (SSCP) analysis as a tool for genetic mapping. Mamm. Genome 4: 627-631, 1993.
5. Brown, D., J. Lydon, M. McLaughlin, A. Stuart-Tilley, R. Tyszkowski, and S. Alper. Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS). Histochem. Cell Biol. 105: 261-267, 1996.
6. Chorney, M., F. W. Shen, J. Michaelson, and E. A. Boyse. Monoclonal antibody to an alloantigenic determinant on β2-microglobulin (β-2M) of the mouse. Immunogenetics 16: 91-93, 1982.
7. - cotransporter from mouse inner medullary collecting duct (mIMCD-3) cells. J. Biol. Chem. 269: 25677-25683, 1994.
8. - cotransporter, BSC-1. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F619-F628, 1996.
9. Ehlers, M. D., E. T. Fung, R. J. O'Brien, and R. L. Huganir. Splice variant-specific interaction of the NMDA receptor subunit NR1 with neuronal intermediate filaments. J. Neurosci. 18: 720-730, 1998.
10. Gamba, G., A. Miyanoshita, M. Lombardi, J. Lytton, W. S. Lee, M. A. Hediger, and S. C. Hebert. Molecular cloning, primary structure, and characterization of two members of the mammalian electroneutral sodium-(potassium)-chloride cotransporter family expressed in kidney. J. Biol. Chem. 269: 17713-17722, 1994.
11. Gamba, G., S. N. Saltzberg, M. Lombardi, A. Miyanoshita, J. Lytton, M. A. Hediger, B. M. Brenner, and S. C. Hebert. Primary structure and functional expression of a cDNA encoding the thiazide-sensitive, electroneutral sodium-chloride cotransporter. Proc. Natl. Acad. Sci. USA 90: 2749-2753, 1993.
12. 3H]bumetanide binding to mouse kidney membranes: identification of corresponding membrane proteins. Am. J. Physiol. 260 (Cell Physiol. 29): C791-C804, 1991.
13. - cotransport. Am. J. Physiol. 241 (Renal Fluid Electrolyte Physiol. 10): F412-F431, 1981.
14. - cotransporter. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F405-F418, 1995.
15. - cotransporter, mBSC2, in the terminal inner medullary collecting duct, the glomerular and extraglomerular mesangium, and the glomerular afferent arteriole. J. Clin. Invest. 98: 723-730, 1996.
16. - cotransporter, rBSC1, on rat thick ascending limbs. Kidney Int. 49: 40-47, 1996.
17. - cotransporter (BSC1) exists in the plasma membrane as a high molecular weight oligomeric complex (Abstract). J. Am. Soc. Nephrol. 8: 37, 1997.
18. - cotransport proteins: a study with monoclonal antibodies. Am. J. Physiol. 269 (Cell Physiol. 38): C1496-C1505, 1995.
19. Manly, K. F. A Macintosh program for storage and analysis of experimental genetic mapping data. Mamm. Genome 4: 303-313, 1993.
20. - entry in mouse medullary thick ascending limbs of Henle. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F177-F187, 1987.
21. Mount, D. B., R. S. Hoover, and S. C. Hebert. The molecular physiology of electroneutral cation-chloride cotransport. J. Membr. Biol. 158: 177-186, 1997.
22. - co-transporter BSC-1 in apical plasma membrane and vesicles of thick ascending limb and macula densa cells (Abstract). J. Am. Soc. Nephrol. 8: 40, 1997.
23. Padgett, R. A., P. J. Grabowski, M. M. Konarska, S. Seiler, and P. A. Sharp. Splicing of messenger RNA precursors. Annu. Rev. Biochem. 55: 1119-1150, 1986.
24. - cotransporter are differentially distributed within the rabbit kidney. Proc. Natl. Acad. Sci. USA 91: 4544-4548, 1994.
25. Plata, C., D. B. Mount, V. Rubio, S. C. Hebert, and G. Gamba. Isoforms of the Na-K-2Cl cotransporter in murine TAL. II. Functional characterization and activation by cAMP. Am. J. Physiol. 276 (Renal Physiol. 45): F359-F366, 1999.
26. - cotransporter, rTSC1, in the rat kidney. Kidney Int. 50: 174-183, 1996.
27. - cotransporter gene (Slc12a1) on mouse chromosome 2. Mamm. Genome 6: 557-558, 1995.
28. - cotransporter. Am. J. Physiol. 273 (Cell Physiol. 42): C1267-C1277, 1997.
29. - cotransporter NKCC2. Nat. Genet. 13: 183-188, 1996.
30. Smith, C. W., J. G. Patton, and B. Nadal-Ginard. Alternative splicing in the control of gene expression. Annu. Rev. Genet. 23: 527-577, 1989.
31. - cotransport in mouse medullary thick ascending limb. J. Membr. Biol. 120: 83-94, 1991.
32. Tsuruoka, S., C. Koseki, S. Muto, K. Tabei, and M. Imai. Axial heterogeneity of potassium transport across hamster thick ascending limb of Henle's loop. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F121-F129, 1994.
33. - cotransporter gene are responsible for antenatal Bartter syndrome. Am. J. Hum. Genet. 62: 1332-1340, 1998.
34. Xu, J. Z., A. E. Hall, L. N. Peterson, M. J. Bienkowski, and T. E. Eessalu, and S. C. Hebert. Localization of the ROMK protein on apical membranes of rat kidney nephron segments. Am. J. Physiol. 273 (Renal Physiol. 42): F739-F748, 1997.