Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 13, 2004, Pages 4690-4694

  Yamauchi, Kozue ^a   Rai, Tatemitsu ^a   Kobayashi, Katsuki ^a   Sohara, Eisei ^a   Suzuki, Tatsunori ^a   Itoh, Tomohiro ^a   Suda, Shin ^a   Hayama, Atsushi ^a   Sasaki, Sei ^a   Uchida, Shinichi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CHLORIDE; CLAUDIN; CLAUDIN 1; CLAUDIN 2; CLAUDIN 3; CLAUDIN 4; MEMBRANE PROTEIN; POTASSIUM CHANNEL; PROTEIN KINASE; PROTEIN KINASE WNK4; PROTEIN ROMK; SODIUM CHLORIDE; THIAZIDE DIURETIC AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL JUNCTION; CELL STRAIN; CHLORIDE TRANSPORT; CONTROLLED STUDY; ENZYME ANALYSIS; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERKALEMIA; HYPERTENSION; IN VIVO STUDY; MEMBRANE PERMEABILITY; MOLECULAR MECHANICS; NONHUMAN; OOCYTE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PSEUDOHYPOALDOSTERONISM; WNK4 GENE; XENOPUS;

ANIMALS; CELL LINE; CELL MEMBRANE PERMEABILITY; CHLORIDES; CLONING, MOLECULAR; DOGS; HUMANS; KIDNEY; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SODIUM; TIGHT JUNCTIONS;

ANIMALIA;

EID: 11144354175     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0306924101     Document Type: Article

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