Modulation of p53 protein conformation and DNA-binding activity by intracellular chelation of zinc

Molecular Carcinogenesis

Volumn 21, Issue 3, 1998, Pages 205-214

  Verhaegh, Gerald W ^a   Parat, Marie Odile ^b   Richard, Marie Jeanne ^b   Hainaut, Pierre ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

Cell cycle; DNA binding; Metal chelation; p53 protein; Zinc

Indexed keywords

N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; PROTEIN P53; ZINC;

ARTICLE; CELL PROLIFERATION; CELL STRAIN MCF 7; CELL SURVIVAL; CHELATION; CONFORMATIONAL TRANSITION; DNA STRAND BREAKAGE; GROWTH REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DNA BINDING;

BINDING SITES; CELL CYCLE; CHELATING AGENTS; CYCLOHEXIMIDE; DNA; DNA-BINDING PROTEINS; ETHYLENEDIAMINES; GENE EXPRESSION REGULATION; HUMANS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN SYNTHESIS INHIBITORS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53; ZINC;

EID: 0031978026     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199803)21:3<205::AID-MC8>3.0.CO;2-K     Document Type: Article

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