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Volumn 115, Issue 1, 2005, Pages 5-12

Regeneration of the pancreatic β cell

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT HUMAN INSULIN;

EID: 13744261497     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200523935     Document Type: Review
Times cited : (110)

References (73)
  • 1
    • 0038280156 scopus 로고    scopus 로고
    • Genes expressed in the developing endocrine pancreas and their importance for stem cell and diabetes research
    • Wells, J.M. 2003. Genes expressed in the developing endocrine pancreas and their importance for stem cell and diabetes research. Diabetes Metab. Res. Rev. 19:191-201.
    • (2003) Diabetes Metab. Res. Rev. , vol.19 , pp. 191-201
    • Wells, J.M.1
  • 2
    • 0348047628 scopus 로고    scopus 로고
    • Gene regulatory factors in pancreatic development
    • Jensen, J. 2004. Gene regulatory factors in pancreatic development. DCK Dyn. 229:176-200.
    • (2004) DCK Dyn. , vol.229 , pp. 176-200
    • Jensen, J.1
  • 3
    • 0028026652 scopus 로고
    • Insulin-dependent diabetes mellitus as an autoimmune disease
    • Bach, J.F. 1994. Insulin-dependent diabetes mellitus as an autoimmune disease. Endocr. Rev. 15:516-542.
    • (1994) Endocr. Rev. , vol.15 , pp. 516-542
    • Bach, J.F.1
  • 4
    • 0020037909 scopus 로고
    • Pancreatic transplantation as a means of insulin delivery
    • Lacy, P.E. 1982. Pancreatic transplantation as a means of insulin delivery. Diabetes Care. 5(Suppl. 1):93-97.
    • (1982) Diabetes Care , vol.5 , Issue.SUPPL. 1 , pp. 93-97
    • Lacy, P.E.1
  • 5
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro, A.M., et al. 2000. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N. Eng. J. Med. 343:230-238.
    • (2000) N. Eng. J. Med. , vol.343 , pp. 230-238
    • Shapiro, A.M.1
  • 6
    • 0035085643 scopus 로고    scopus 로고
    • Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol
    • Ryan, E.A., et al. 2001. Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol. Diabetes. 50:710-719.
    • (2001) Diabetes , vol.50 , pp. 710-719
    • Ryan, E.A.1
  • 7
    • 0029379704 scopus 로고
    • Peripheral regeneration and central sprouting of sensory neurone axons in Aplysia californica following nerve injury
    • Steffensen, I., Dulin, M.F., Walters, E.T., and Morris, C.E. 1995. Peripheral regeneration and central sprouting of sensory neurone axons in Aplysia californica following nerve injury. J. Exp. Biol. 198:2067-2078.
    • (1995) J. Exp. Biol. , vol.198 , pp. 2067-2078
    • Steffensen, I.1    Dulin, M.F.2    Walters, E.T.3    Morris, C.E.4
  • 8
    • 0029738482 scopus 로고    scopus 로고
    • Local and systemic alterations in cyclic 3′,5′ AMP phosphodiesterase activity in relation to tail regeneration under hypothyroidism and T4 replacement in the lizard, Mabuya carinata
    • Ramachandra, A.V., Swamy, M.S., and Kurup, A.K. 1996. Local and systemic alterations in cyclic 3′,5′ AMP phosphodiesterase activity in relation to tail regeneration under hypothyroidism and T4 replacement in the lizard, Mabuya carinata. Mol. Reprod. Dev. 45:48-51.
    • (1996) Mol. Reprod. Dev. , vol.45 , pp. 48-51
    • Ramachandra, A.V.1    Swamy, M.S.2    Kurup, A.K.3
  • 9
    • 0037032811 scopus 로고    scopus 로고
    • A tail of transdifferentiation
    • Stocum, D.L. 2002. A tail of transdifferentiation. Science. 298:1901-1903.
    • (2002) Science , vol.298 , pp. 1901-1903
    • Stocum, D.L.1
  • 10
    • 0036266272 scopus 로고    scopus 로고
    • β-cell neogenesis during prolonged hyperglycemia in rats
    • Lipsett, M., and Finegood, D.T. 2002. β-cell neogenesis during prolonged hyperglycemia in rats. Diabetes. 51:1834-1841.
    • (2002) Diabetes , vol.51 , pp. 1834-1841
    • Lipsett, M.1    Finegood, D.T.2
  • 11
    • 0028243350 scopus 로고
    • Transitional cells in the regenerating pancreas
    • Gu, D., Lee, M.S., Krahl, T., and Sarvetnick, N. 1994. Transitional cells in the regenerating pancreas. Development. 120:1873-1881.
    • (1994) Development , vol.120 , pp. 1873-1881
    • Gu, D.1    Lee, M.S.2    Krahl, T.3    Sarvetnick, N.4
  • 12
    • 0035122488 scopus 로고    scopus 로고
    • Endocrine pancreas plasticity under physiological and pathological conditions
    • Bernard-Kargar, C., and Ktorza, A. 2001. Endocrine pancreas plasticity under physiological and pathological conditions. Diabetes. 50(Suppl. 1):S30-S35.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Bernard-Kargar, C.1    Ktorza, A.2
  • 13
    • 0027439729 scopus 로고
    • Effect of homologous placental lactogens, prolactins, and growth hormones on islet β-cell division and insulin secretion in rat, mouse, and human islets: Implication for placental lactogen regulation of islet function during pregnancy
    • Brelje, T.C., et al. 1993. Effect of homologous placental lactogens, prolactins, and growth hormones on islet β-cell division and insulin secretion in rat, mouse, and human islets: implication for placental lactogen regulation of islet function during pregnancy. Endocrinology. 132:879-887.
    • (1993) Endocrinology , vol.132 , pp. 879-887
    • Brelje, T.C.1
  • 14
    • 0029166144 scopus 로고
    • In vivo cell transformation: Neogenesis of beta cells from pancreatic ductal cells
    • Rosenberg, L. 1995. In vivo cell transformation: neogenesis of beta cells from pancreatic ductal cells. Cell Transplant. 4:371-383.
    • (1995) Cell Transplant. , vol.4 , pp. 371-383
    • Rosenberg, L.1
  • 15
    • 0032533441 scopus 로고    scopus 로고
    • Transdifferentiation versus stem cell hypothesis for the regeneration of islet beta-cells in the pancreas
    • Bouwens, L. 1998. Transdifferentiation versus stem cell hypothesis for the regeneration of islet beta-cells in the pancreas. Microsc. Res. Tech. 15:332-336.
    • (1998) Microsc. Res. Tech. , vol.15 , pp. 332-336
    • Bouwens, L.1
  • 16
    • 0024508097 scopus 로고
    • Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion
    • Bonner-Weir, S., Deery, D., Leahy, J.L., and Weir, G.C. 1989. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes. 38:49-53.
    • (1989) Diabetes , vol.38 , pp. 49-53
    • Bonner-Weir, S.1    Deery, D.2    Leahy, J.L.3    Weir, G.C.4
  • 17
    • 0030013463 scopus 로고    scopus 로고
    • Growth factors in the regenerating pancreas of gamma-interferon transgenic mice
    • Arnush, M., et al. 1996. Growth factors in the regenerating pancreas of gamma-interferon transgenic mice. Lab. Invest. 74:985-990.
    • (1996) Lab. Invest. , vol.74 , pp. 985-990
    • Arnush, M.1
  • 18
    • 0034121735 scopus 로고    scopus 로고
    • Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
    • Herrera, P.L. 2000. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development. 127:2317-2322.
    • (2000) Development , vol.127 , pp. 2317-2322
    • Herrera, P.L.1
  • 19
    • 0036340074 scopus 로고    scopus 로고
    • + cells are islet progenitors and are distinct from duct progenitors
    • + cells are islet progenitors and are distinct from duct progenitors. Development. 129:2447-2457.
    • (2002) Development , vol.129 , pp. 2447-2457
    • Gu, G.1    Dubauskaite, J.2    Melton, D.A.3
  • 20
    • 4444338370 scopus 로고    scopus 로고
    • Beta-cell precursors - A work in progress
    • Weir, G.G., and Bonner-Weir, S. 2004. Beta-cell precursors - a work in progress. Nat. Biotechnol. 22:1-2.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1-2
    • Weir, G.G.1    Bonner-Weir, S.2
  • 21
    • 4444320484 scopus 로고    scopus 로고
    • Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages
    • Seaberg, R.M., et al. 2004. Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nat. Biotechnol. 22:1115-1124.
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1115-1124
    • Seaberg, R.M.1
  • 22
    • 3242784831 scopus 로고    scopus 로고
    • Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting
    • Suzuki, A., Nakauchi, H., and Taniguchi, H. 2004. Prospective isolation of multipotent pancreatic progenitors using flow-cytometric cell sorting. Diabetes. 53:2143-2152.
    • (2004) Diabetes , vol.53 , pp. 2143-2152
    • Suzuki, A.1    Nakauchi, H.2    Taniguchi, H.3
  • 23
    • 0036070177 scopus 로고    scopus 로고
    • Pancreatic stem cells
    • Bonner-Wier, S., and Sharma, A. 2002. Pancreatic stem cells. J. Pathol. 197:519-526.
    • (2002) J. Pathol. , vol.197 , pp. 519-526
    • Bonner-Wier, S.1    Sharma, A.2
  • 24
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor, Y., Brown, J., Marinez, O.I., and Melton, D. 2004. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature. 429:41-46.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Marinez, O.I.3    Melton, D.4
  • 25
    • 0037013147 scopus 로고    scopus 로고
    • Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
    • Pelengaris, S., Khan, M., and Evan, G.I. 2002. Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell. 109:321-334.
    • (2002) Cell , vol.109 , pp. 321-334
    • Pelengaris, S.1    Khan, M.2    Evan, G.I.3
  • 26
    • 0021697880 scopus 로고
    • Twin-to-twin pancreas transplantation: Reversal and reenactment of the pathogenesis of type I diabetes
    • Sutherland, D.E., et al. 1984. Twin-to-twin pancreas transplantation: reversal and reenactment of the pathogenesis of type I diabetes. Trans. Assoc. Am. Physicians. 97:80-87.
    • (1984) Trans. Assoc. Am. Physicians , vol.97 , pp. 80-87
    • Sutherland, D.E.1
  • 27
    • 3042737844 scopus 로고    scopus 로고
    • Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4
    • Ogawa, N., List, J.F., Habener, J.F., and Maki, T. 2004. Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4. Diabetes. 53:1700-1705.
    • (2004) Diabetes , vol.53 , pp. 1700-1705
    • Ogawa, N.1    List, J.F.2    Habener, J.F.3    Maki, T.4
  • 28
    • 0344338626 scopus 로고
    • Prevention of type 1 diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation
    • Ikehara, S., et al. 1985. Prevention of type 1 diabetes in nonobese diabetic mice by allogeneic bone marrow transplantation. Proc. Natl. Acad. Sci. U. S. A. 82:7743-7747.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 7743-7747
    • Ikehara, S.1
  • 29
    • 0029671326 scopus 로고    scopus 로고
    • Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice
    • Li, H., et al. 1996. Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice. J. Immunol. 156:380-388.
    • (1996) J. Immunol. , vol.156 , pp. 380-388
    • Li, H.1
  • 30
    • 0035987925 scopus 로고    scopus 로고
    • Distinct characteristics and features of allogeneic chimerism in the NOD mouse model of autoimmune diabetes
    • Zorina, T.D., et al. 2002. Distinct characteristics and features of allogeneic chimerism in the NOD mouse model of autoimmune diabetes. Cell Transplant. 11:113-123.
    • (2002) Cell Transplant. , vol.11 , pp. 113-123
    • Zorina, T.D.1
  • 31
    • 0034939166 scopus 로고    scopus 로고
    • Reversal of established autoimmune diabetes by restoration of endogenous β cell function
    • doi:10.1172/JCI200112335
    • Ryu, S., Kodama, S., Ryu, K., Schoenfeld, D.A., and Faustman, D.L. 2001. Reversal of established autoimmune diabetes by restoration of endogenous β cell function. J. Clin. Invest. 108:63-72. doi:10.1172/JCI200112335.
    • (2001) J. Clin. Invest. , vol.108 , pp. 63-72
    • Ryu, S.1    Kodama, S.2    Ryu, K.3    Schoenfeld, D.A.4    Faustman, D.L.5
  • 32
    • 0037820427 scopus 로고    scopus 로고
    • Bone marrow-derived stem cells initiate pancreatic regeneration
    • Hess, D., et al. 2003. Bone marrow-derived stem cells initiate pancreatic regeneration. Nat. Biotechnol. 21:763-770.
    • (2003) Nat. Biotechnol. , vol.21 , pp. 763-770
    • Hess, D.1
  • 33
    • 0038110577 scopus 로고    scopus 로고
    • Recovery of the endogenous beta cell function in autoimmune diabetes
    • Zorina, T.D., et al. 2003. Recovery of the endogenous beta cell function in autoimmune diabetes. Stem Cells. 21:377-388.
    • (2003) Stem Cells , vol.21 , pp. 377-388
    • Zorina, T.D.1
  • 34
    • 0025942662 scopus 로고
    • In vivo effect of FK506 on human pancreatic islets
    • Ricordi, C., et al. 1991. In vivo effect of FK506 on human pancreatic islets. Transplantation. 52:519-526.
    • (1991) Transplantation , vol.52 , pp. 519-526
    • Ricordi, C.1
  • 35
    • 0029056853 scopus 로고
    • Transcriptional inhibition of insulin by FK506 and possible involvement of FK506 binding protein-12 in pancreatic β-cell
    • Tamura, K., et al. 1995. Transcriptional inhibition of insulin by FK506 and possible involvement of FK506 binding protein-12 in pancreatic β-cell. Transplantation. 59:1606-1615.
    • (1995) Transplantation , vol.59 , pp. 1606-1615
    • Tamura, K.1
  • 36
    • 10744228630 scopus 로고    scopus 로고
    • Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets
    • Bell, E., et al. 2003. Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets. Diabetes. 52:2731-2739.
    • (2003) Diabetes , vol.52 , pp. 2731-2739
    • Bell, E.1
  • 37
    • 0038522555 scopus 로고    scopus 로고
    • Specific and combined effects of insulin and glucose on functional pancreatic β-cell mass in vivo and in adult rats
    • Paris, M., Bernard-Kargar, C., Berthault, M.F., Bouwens, L., and Ktorza, A. 2003. Specific and combined effects of insulin and glucose on functional pancreatic β-cell mass in vivo and in adult rats. Endocrinology. 144:2717-2727.
    • (2003) Endocrinology , vol.144 , pp. 2717-2727
    • Paris, M.1    Bernard-Kargar, C.2    Berthault, M.F.3    Bouwens, L.4    Ktorza, A.5
  • 38
    • 0036828227 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats
    • Farilla, L., et al. 2002. Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats. Endocrinology. 143:4397-4408.
    • (2002) Endocrinology , vol.143 , pp. 4397-4408
    • Farilla, L.1
  • 39
    • 1442326000 scopus 로고    scopus 로고
    • No evidence for significant transdifferentiation of bonemarrow into pancreatic β-cells in vivo
    • Lechner, A., et al. 2004. No evidence for significant transdifferentiation of bonemarrow into pancreatic β-cells in vivo. Diabetes. 53:616-623.
    • (2004) Diabetes , vol.53 , pp. 616-623
    • Lechner, A.1
  • 40
    • 0242582180 scopus 로고    scopus 로고
    • Islet regeneration during the reversal of autoimmune diabetes in NOD mice
    • Kodama, S., Kühtreiber, W., Fujimura, S., Dale, E.A., and Faustman, D.L. 2003. Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science. 302:1223-1227.
    • (2003) Science , vol.302 , pp. 1223-1227
    • Kodama, S.1    Kühtreiber, W.2    Fujimura, S.3    Dale, E.A.4    Faustman, D.L.5
  • 41
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cell lines derived from human blastocysts
    • Thomson, J.A., et al. 1998. Embryonic stem cell lines derived from human blastocysts. Science. 282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1
  • 42
    • 0032506231 scopus 로고    scopus 로고
    • Derivation of pluripotent stem cells from cultured human primordial germ cells
    • Shamblott, M.J., et al. 1998. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc. Natl. Acad. Sci. U. S. A. 95:13726-13731.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 13726-13731
    • Shamblott, M.J.1
  • 43
    • 12144288049 scopus 로고    scopus 로고
    • Derivation of embryonic stem-cell lines from human blastocysts
    • Cowan, C.A., et al. 2004. Derivation of embryonic stem-cell lines from human blastocysts. N. Engl. J. Med. 350:1353-1356.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1353-1356
    • Cowan, C.A.1
  • 44
    • 1542328965 scopus 로고    scopus 로고
    • Plasticity of adult stem cells
    • Wagers, A.J., and Weissman, I.L. 2004. Plasticity of adult stem cells. Cell. 116:639-648.
    • (2004) Cell , vol.116 , pp. 639-648
    • Wagers, A.J.1    Weissman, I.L.2
  • 45
    • 12144286557 scopus 로고    scopus 로고
    • Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst
    • Hwang, W.S., et al. 2004. Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. Science. 303:1669-1674.
    • (2004) Science , vol.303 , pp. 1669-1674
    • Hwang, W.S.1
  • 46
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky, N., et al. 2001. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science. 292:1389-1394.
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1
  • 47
    • 0029795884 scopus 로고    scopus 로고
    • Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact
    • Beattie, G.M., Rubin, J.S., Mally, M.I., Otonkoski, T., and Hayek, A. 1996. Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact. Diabetes. 45:1223-1228.
    • (1996) Diabetes , vol.45 , pp. 1223-1228
    • Beattie, G.M.1    Rubin, J.S.2    Mally, M.I.3    Otonkoski, T.4    Hayek, A.5
  • 48
    • 0036230386 scopus 로고    scopus 로고
    • Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas
    • Selander, L., and Edlund, H. 2002. Nestin is expressed in mesenchymal and not epithelial cells of the developing mouse pancreas. Mech. Dev. 113:189-192.
    • (2002) Mech. Dev. , vol.113 , pp. 189-192
    • Selander, L.1    Edlund, H.2
  • 49
    • 0141643297 scopus 로고    scopus 로고
    • Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet
    • Treutelaar, M.K., et al. 2003. Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet. Diabetes. 52:2503-2512.
    • (2003) Diabetes , vol.52 , pp. 2503-2512
    • Treutelaar, M.K.1
  • 51
    • 0037235364 scopus 로고    scopus 로고
    • Transgenic mice with green fluorescent protein-labeled pancreatic beta-cells
    • Hara, M., et al. 2003. Transgenic mice with green fluorescent protein-labeled pancreatic beta-cells. Am. J. Physiol. Endocrinol. Metab. 284:E177-E183.
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.284
    • Hara, M.1
  • 52
    • 0141995487 scopus 로고    scopus 로고
    • Body window-enabled in vivo multicolor imaging of transplanted mouse islets expressing an insulin-timer fusion protein
    • Bertera, S., et al. 2003. Body window-enabled in vivo multicolor imaging of transplanted mouse islets expressing an insulin-timer fusion protein. BioTechniques. 35:718-722.
    • (2003) BioTechniques , vol.35 , pp. 718-722
    • Bertera, S.1
  • 53
    • 0033694301 scopus 로고    scopus 로고
    • Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    • Lagasse, E., et al. 2000. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat. Med. 6:1229-1234.
    • (2000) Nat. Med. , vol.6 , pp. 1229-1234
    • Lagasse, E.1
  • 55
    • 0242485429 scopus 로고    scopus 로고
    • The role of cell type in bone healing mediated by ex vivo gene therapy
    • Rose, T., et al. 2003. The role of cell type in bone healing mediated by ex vivo gene therapy. Langenbecks Arch. Surg. 388:347-355.
    • (2003) Langenbecks Arch. Surg. , vol.388 , pp. 347-355
    • Rose, T.1
  • 56
    • 0034071364 scopus 로고    scopus 로고
    • Converting hepatocytes to β-cells - A new approach for diabetes?
    • News & Views
    • Kahn, A. 2000. Converting hepatocytes to β-cells - a new approach for diabetes? (News & Views). Nat. Med. 6:505-506.
    • (2000) Nat. Med. , vol.6 , pp. 505-506
    • Kahn, A.1
  • 57
    • 0034712013 scopus 로고    scopus 로고
    • Patients' voices: The powerful sound in stem cell debate
    • Perry, D. 2000. Patients' voices: the powerful sound in stem cell debate. Science. 287:1423.
    • (2000) Science , vol.287 , pp. 1423
    • Perry, D.1
  • 58
    • 0037183884 scopus 로고    scopus 로고
    • Little evidence for developmental plasticity of adult hematopoietic stem cells
    • Wagers, A.J., Sherwood, R.L., Christensen, J.L., and Weissman, I.L. 2002. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science. 297:2256-2259.
    • (2002) Science , vol.297 , pp. 2256-2259
    • Wagers, A.J.1    Sherwood, R.L.2    Christensen, J.L.3    Weissman, I.L.4
  • 59
    • 0037464574 scopus 로고    scopus 로고
    • Cell fusion is the principal source of bone-marrow-derived hepatocytes
    • Wang, X., et al. 2003. Cell fusion is the principal source of bone-marrow-derived hepatocytes. Nature. 422:897-901.
    • (2003) Nature , vol.422 , pp. 897-901
    • Wang, X.1
  • 60
    • 10744233909 scopus 로고    scopus 로고
    • Little evidence of trans-differentiation of bone marrow-derived cells into pancreatic beta cells
    • Choi, J.B., et al. 2003. Little evidence of trans-differentiation of bone marrow-derived cells into pancreatic beta cells. Diabetologia. 46:1366-1374.
    • (2003) Diabetologia , vol.46 , pp. 1366-1374
    • Choi, J.B.1
  • 61
    • 0242584006 scopus 로고    scopus 로고
    • Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes
    • Alvarez-Dolado, M., et al. 2003. Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature. 425:968-973.
    • (2003) Nature , vol.425 , pp. 968-973
    • Alvarez-Dolado, M.1
  • 62
    • 0037364517 scopus 로고    scopus 로고
    • In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion
    • doi:10.1172/JCI200316502
    • Ianus, A., Holz, G.G., Theise, N.D., and Hussain, M.A. 2003. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J. Clin. Invest. 111:843-850. doi:10.1172/JCI200316502.
    • (2003) J. Clin. Invest. , vol.111 , pp. 843-850
    • Ianus, A.1    Holz, G.G.2    Theise, N.D.3    Hussain, M.A.4
  • 63
    • 0034623757 scopus 로고    scopus 로고
    • Glucose dependent insulin release from genetically engineered K cells
    • Cheung, A.T., et al. 2000. Glucose dependent insulin release from genetically engineered K cells. Science. 290:1959-1962.
    • (2000) Science , vol.290 , pp. 1959-1962
    • Cheung, A.T.1
  • 64
    • 0034068602 scopus 로고    scopus 로고
    • Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia
    • Ferber, S., et al. 2000. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat. Med. 6:568-572.
    • (2000) Nat. Med. , vol.6 , pp. 568-572
    • Ferber, S.1
  • 65
    • 0041856137 scopus 로고    scopus 로고
    • Functional, persistent, and extended liver to pancreas transdifferentiation
    • Ber, I., et al. 2003. Functional, persistent, and extended liver to pancreas transdifferentiation. J. Biol. Chem. 278:31950-31957.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31950-31957
    • Ber, I.1
  • 66
    • 0037162551 scopus 로고    scopus 로고
    • Characterization of the expression of MHC proteins in human embryonic stem cells
    • Drukker, M., et al. 2002. Characterization of the expression of MHC proteins in human embryonic stem cells. Proc. Natl. Acad. Sci. U. S. A 99:9864-9869.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 9864-9869
    • Drukker, M.1
  • 67
    • 3543018487 scopus 로고    scopus 로고
    • Human embryonic stem cells possess immune-privileged properties
    • Li, L., et al. 2004. Human embryonic stem cells possess immune-privileged properties. Stem Cells. 22:448-456.
    • (2004) Stem Cells , vol.22 , pp. 448-456
    • Li, L.1
  • 68
    • 1542723300 scopus 로고    scopus 로고
    • Stem cells, redux
    • Kennedy, D. 2004. Stem cells, redux. Science. 303:1581.
    • (2004) Science , vol.303 , pp. 1581
    • Kennedy, D.1
  • 69
    • 0031569177 scopus 로고    scopus 로고
    • CD3 antibody-induced dominant self tolerance in overt autoimmunity in non-obese diabetic mice
    • Chatenoud, L., Primo, J., and Bach, J.-F. 1997. CD3 antibody-induced dominant self tolerance in overt autoimmunity in non-obese diabetic mice. J. Immunol. 158:2947-2954.
    • (1997) J. Immunol. , vol.158 , pp. 2947-2954
    • Chatenoud, L.1    Primo, J.2    Bach, J.-F.3
  • 70
    • 0037198420 scopus 로고    scopus 로고
    • Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
    • Herold, K.C., et al. 2002. Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N. Engl. J. Med. 346:1692-1698.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1692-1698
    • Herold, K.C.1
  • 71
    • 0037313086 scopus 로고    scopus 로고
    • CD3-specific antibody-induced active tolerance
    • Chatenoud, L. 2003. CD3-specific antibody-induced active tolerance. Nat. Rev. Immunol. 3:123-132.
    • (2003) Nat. Rev. Immunol. , vol.3 , pp. 123-132
    • Chatenoud, L.1
  • 72
    • 10744228165 scopus 로고    scopus 로고
    • Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance
    • Zheng, X.X., et al. 2003. Favorably tipping the balance between cytopathic and regulatory T cells to create transplantation tolerance. Immunity. 19:503-514.
    • (2003) Immunity , vol.19 , pp. 503-514
    • Zheng, X.X.1
  • 73
    • 4644297765 scopus 로고    scopus 로고
    • Antisense oligonucleotide downregulating co-stimulation confer diabetes-preventive properties to NOD dendritic cells
    • Machen, J., et al. 2004. Antisense oligonucleotide downregulating co-stimulation confer diabetes-preventive properties to NOD dendritic cells. J. Immunol. 173:4331-4341.
    • (2004) J. Immunol. , vol.173 , pp. 4331-4341
    • Machen, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.