Cutting edge: Memory CD8 T cell maturation occurs independently of CD8αα

Journal of Immunology

Volumn 175, Issue 9, 2005, Pages 5619-5623

  Chandele, Anmol ^a   Kaech, Susan M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CD8ALPHA ALPHA ANTIGEN; CD8ALPHA ANTIGEN; INTERLEUKIN 7 RECEPTOR; INTERLEUKIN 7 RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; CELL MATURATION; CELL PROTECTION; CELL SPECIFICITY; CELL SURFACE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; INFECTION PREVENTION; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROCESS CONTROL; STEM CELL; T LYMPHOCYTE ACTIVATION; VIRUS INFECTION;

EID: 27144441379     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.9.5619     Document Type: Article

References (19)

1. Fry, T. J., and C. L. Mackall. 2005. The many faces of IL-7: from lymphopoiesis to peripheral T cell maintenance. J. Immunol. 174: 6571-6576.
2. Kaech, S. M., J. T. Tan, E. J. Wherry, B. T. Konieczny, C. D. Surh, and R. Ahmed. 2003. Selective expression of the incerleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4: 1191-1198.
3. Schluns, K. S., W. C. Kieper, S. C. Jameson, and L. Lefrancois. 2000. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat. Immunol. 1: 426-432.
4. + memory T cell subsets. Proc. Natl. Acad. Sci. USA 101: 5610-5615.
5. Madakamutil, L. T., U. Christen, C. J. Lena, Y., Wang-Zhu, A. Attinger, M. Sundarrajan, W. Ellmeier, M. G. von Herrath, P. Jensen, D. R. Littman, and H, Cheroutre. 2004. CD8αα-mediated survival and differentiation of CD8 memory T cell precursors. Science 304: 590-593.
6. Leishman, A. J., O. V. Naidenko, A. Attinger, F. Koning, C. J. Lena, Y. Xiong, H. C. Chang, E. Reinherz, M. Kronenberg, and H. Cheroutre. 2001. T cell responses modulated through interaction between CD8αα and the nonclassical MHC class I molecule, TL. Science 294: 1936-1939.
7. Ellmeier, W., M. J. Sunshine, K. Losos, and D. R. Littman. 1998. Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocyies and in thymus-independent T cells. Immunity 9: 485-496.
8. Wherry, E. J., and R. Ahmed. 2004. Memory CD8 T cell differentiation during viral infection. J. Virol. 78: 5535-5545.
9. Ahmed, R., A. Salmi, L. D. Butler, J. M. Chiller, and M. B. Oldstone. 1984. Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice: role in suppression of cytotoxic T lymphocyte response and viral persistence. J. Exp. Med. 160: 521-540.
10. Wherry, E. J., J. N. Blattman, K. Murali-Krishna, R. van der Most, and R. Ahmed. 2003. Viral persistence alters CD8 T cell immunodominance and tissue distribution and results in distinct stages of functional impairment. J. Virol. 77: 4911-4927.
11. Davies, M. D., and D. M. Parrott. 1981. Preparation and purification of lymphocytes from the epithelium and lamina propria of murine small intestine. Gut 22: 481-488.
12. Murali-Krishna, K.J. D. Airman, M. Suresh, D. J. Soutdive, A. J. Zajac, J. D. Miller, J. Slansky, and R. Ahmed. 1998. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8: 177-187.
13. Wherry, E. J., V. Teichgraber, T. C. Becker, D. Masopust, S. M. Kaech, R. Antia, U. H. von Andrian, and R. Ahmed. 2003. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 4: 225-234.
14. Hennecke, S., and P. Cosson. 1993. Role of transmembrane domains in assembly and intracellular transport of the CD8 molecule. J. Biol. Chem. 268: 26607-26612.
15. Maile, R., C. A. Siler, S. E. Kerry, K. E. Midkiff, E. J. Collins, and J. A. Frelinger. 2005. Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo. J. Immunol. 174: 619-627.
16. Ahmed, R., and D. Gray. 1996. Immunological memory and protective immunity: understanding their relation. Science 272: 54-60.
17. Lanzavecchia, A., and F. Sallusto. 2002. Progressive differentiation and selection of the fittest in the immune response. Nat. Rev. Immunol. 2: 982-987.
18. Zhong, W., and E. L. Reinherz. 2005. Complexity of CD8αα homodimer expression and function during antiviral CD8 T cell memoty generation. Eur. J. Immunol. In press.
19. Williams, M. A., and M. J. Bevan. 2005- Cutting edge: a single MHC class Ia is sufficient for CD8 memory T cell differentiation. J. Immunol. 175: 2066-2069.