How a small change in retinal leads to G-protein activation: Initial events suggested by molecular dynamics calculations

Proteins: Structure, Function and Genetics

Volumn 66, Issue 3, 2007, Pages 559-574

  Crozier, Paul S ^a   Stevens, Mark J ^a   Woolf, Thomas B ^b  

^a SANDIA NATIONAL LABORATORIES   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

G protein coupled receptors; Membrane protein; Photoisomerization; Rhodopsin; Simulation

Indexed keywords

ALANINE; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; RETINAL; RHODOPSIN; SCHIFF BASE;

CIS TRANS ISOMERISM; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; ENERGY TRANSFER; ISOMERIZATION; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PHOTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ALANINE; ANIMALS; BINDING SITES; CATTLE; COMPUTER SIMULATION; GTP-BINDING PROTEINS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; RETINALDEHYDE; RHODOPSIN; X-RAY DIFFRACTION;

EID: 33846218265     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21175     Document Type: Conference Paper

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