The third extracellular loop of G-protein-coupled receptors: More than just a linker between two important transmembrane helices

Biochemical Society Transactions

Volumn 32, Issue 6, 2004, Pages 1048-1050

  Lawson, Z ^a   Wheatley, M ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Agonist; Binding; G piotein coupled receptor (GPCR); Peptide hormone; Receptor activation

Indexed keywords

11 CIS RETINAL; BIOGENIC AMINE; G PROTEIN COUPLED RECEPTOR; LIGAND; LYSINE; NEUROTRANSMITTER; PEPTIDE DERIVATIVE; PEPTIDE HORMONE; RHODOPSIN; SCHIFF BASE;

BINDING AFFINITY; CHROMATOPHORE; CONFERENCE PAPER; HUMAN; HYDROPHOBICITY; LIGAND BINDING; LIGAND SELECTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE; RECEPTOR ACTIVATION; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; HUMANS; LIGANDS; MODELS, MOLECULAR; PEPTIDE HORMONES; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, G-PROTEIN-COUPLED;

EID: 10644247627     PISSN: 03005127     EISSN: None     Source Type: Journal    
DOI: 10.1042/BST0321048     Document Type: Conference Paper

References (18)

1. Palczewski, K., Kumasaka, T., Hori, T., Behnke, C.A., Motoshima, H., Fox, B.A., Le Trong, I., Teller, D.C., Okada, T., Stenkamp, R.E. et al. (2000) Science 289, 739-745
2. Lu, Z.-L., Saldanha, J.W. and Hulme, E.C. (2002) Trends Pharmacol. Sci. 23, 140-146
3. Décaillot, F.M., Befort, K., Filliol, D., Yue, S.Y., Walker, P. and Kieffer, B.L. (2003) Nat. Struct. Biol. 10, 629-636
4. Hawtin, S.R., Davies, A.R.L., Matthews, G. and Wheatley, M. (2001) Biochem. J. 357, 73-81
5. Ohyama, K., Yamano, Y., Sano, T., Nakagomi, Y., Hamakubo, T., Morishima, I. and Inagami, T. (1995) Regul. Pept. 57, 141-147
6. Zhao, M.-M., Gaivin, R.J. and Perez, D.M. (1998) Mol. Pharmacol. 53, 524-529
7. Kosugi, S. and Mori, T. (1994) FEBS Lett. 349, 89-92
8. Hines, J., Heerding, J.N., Fluharty, S.J. and Yee, D.K. (2001) J. Pharmacol. Exp. Ther. 298, 665-673
9. Feng, Y.H., Noda, K., Saad, Y., Liu, X.P., Husain, A. and Karnik, S.S. (1995) J. Biol. Chem. 270, 12846-12850
10. Gigoux, V., Escrieut, C., Fehrentz, J.-A., Poirot, S., Maigret, B., Moroder, L., Gully, D., Martinez, J., Vaysse, N. and Fourmy, D. (1999) J. Biol. Chem. 274, 20457-20464
11. Sohn, J., Ryu, K.-S., Sievert, G., Jeoung, M.-K., Ji, I. and Ji, T.H. (2002) J. Biol. Chem. 277, 50165-50175
12. Chauvin, S., Bérault, A., Lerrant, Y., Hibert, M. and Counis, R. (2000) Mol. Pharmacol. 57, 625-633
13. Flanagan, C.A, Becker, I.I., Davidson, J.S., Wakefield, I.K., Zhou, W., Sealfon, S.C. and Miller, R.P. (1994) J. Biol. Chem. 269, 22636-22641
14. Ryu, K.-S., Gilchrist, R.L., Ji, I., Kim, S.-J. and Ji, T.H. (1996) J. Biol. Chem. 271, 7301-7304
15. Huang, X.P., Willaims, F.E., Peseckis, S.M. and Messer, W.S. (1999) Mol. Pharmacol. 56, 775-783
16. Richard, F., Barroso, S., Nicolas-Ethève, D., Kitabgi, P. and Labbé-Jullié, C. (2001) Eur. J. Pharmacol. 433, 63-71
17. Hoffmann, C., Moro, S., Nicholas, R.A., Harden, T.K. and Jacobson, K.A. (1999) J. Biol. Chem. 274, 14639-14647
18. Ballesteros, J.A. and Weinstein, H. (1995) Methods Neurosci. 25, 366-428