Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant

Journal of Biological Chemistry

Volumn 271, Issue 50, 1996, Pages 32337-32342

  Han, May ^a   Lin, Steven W ^b   Minkova, Mariya ^a,c   Smith, Steven O ^a   Sakmar, Thomas P ^b  

^a YALE UNIVERSITY   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11 CIS RETINAL; ALANINE; AMINO ACID; GLYCINE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYLAMINE; METHIONINE; OPSIN; PHENYLALANINE; PIGMENT; RECEPTOR; RETINAL; RHODOPSIN; TRANSDUCIN; TRYPTOPHAN; VALINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CHROMATOPHORE; GENE; MODEL; MONKEY; MUTANT; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; THERMOSTABILITY;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; CATTLE; GLYCINE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OPSIN; PHENOTYPE; PHENYLALANINE; RHODOPSIN; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSDUCIN;

ANIMALIA; BOVINAE;

EID: 0029730779     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.50.32337     Document Type: Article

References (36)

1. Kobilka, B. K., Kobilka, T. S., Daniel, K., Regan, H. W., Caron, M. G. & Lefkowitz, R. J. (1988) Science 240, 1310-1316
2. Asenjo, A. B., Rim, J. & Oprian, D. D. (1994) Neuron 12, 1131-1138
3. Franke, R. R., König, B., Sakmar, T. P., Khorana, H. G. & Hofmann, K. P. (1990) Science 250, 123-125
4. Ernst, O. P., Hofmann, K. P. & Sakmar, T. P. (1995) J. Biol. Chem. 270, 10580-10586
5. Han, M., Lin, S. W., Smith, S. O. & Sakmar, T. P. (1996) J. Biol. Chem. 271, 32330-32336
6. Schertler, C. F. X., Villa, C. & Henderson, R. (1993) Nature 362, 770-772
7. Han, M., DeDecker, B. S. & Smith, S. O. (1993) Biophys. J. 65, 899-906
8. Han, M. & Smith, S. O. (1995) Biochemistry 34, 1425-1432
9. Birge, R. R., Murray, L., Pierce, B., Akita, H., Balogh-Nair, V., Findsen, L. & Nakanishi, K. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 4117-4121
10. Baldwin, J. M. (1993) EMBO J. 12, 1693-1703
11. Probst, W. C., Snyder, L. A., Schuster, D. I., Brosius, J. & Sealfon, S. C. (1992) DNA Cell Biol. 11, 1-20
12. Lin, S. W., Imamoto, Y., Fukada, Y., Shichida, Y., Yoshizawa, T. & Mathies, R. A. (1994) Biochemistry 33, 2151-2160
13. Lin, S. W. & Sakmar, T. P. (1996) Biochemistry 35, 11149-11159
14. Nakayama, T. A. & Khorana, H. G. (1991) J. Biol. Chem. 266, 4269-4275
15. Garcia, P. D., Onrust, R., Bell, S. M., Sakmar, T. P. & Bourne, H. R. (1995) EMBO J. 14, 4460-4469
16. Sakmar, T. P., Franke, R. R. & Khorana, H. G. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 8309-8313
17. Cohen, G. B., Oprian, D. D. & Robinson, P. R. (1992) Biochemistry 31, 12592-12601
18. Alkorta, I. & Du, P. (1994) Protein Eng. 7, 1231-1238
19. Sakmar, T. P., Franke, R. R. & Khorana, H. G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 3079-3083
20. Zhukovsky, E. A. & Oprian, D. D. (1989) Science 246, 928-930
21. Zvyaga, T. A., Min, K. C., Beck, M. & Sakmar, T. P. (1993) J. Biol. Chem. 268, 4661-4667; Correction (1994) J. Biol. Chem. 269, 13056
22. Zhukovsky, E. A., Robinson, P. R. & Oprian, D. D. (1992) Biochemistry 31, 10400-10405
23. Schertler, C. F. X. & Hargrave, P. A. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11578-11582
24. Nakayama, T. A. & Khorana, H. G. (1990) J. Biol. Chem. 265, 15762-15769
25. Zhang, H., Lerro, K. A., Yamamoto, T., Lien, T. H., Sastry, L., Gawinowicz, M. A. & Nakanishi, K. (1994) J. Am. Chem. Soc. 116, 10165-10173
26. Chan, T., Lee, M. & Sakmar, T. P. (1992) J. Biol. Chem. 267, 9478-9480
27. Donnelly, D., Findlay, J. B. C. & Blundell, T. L. (1994) Receptors & Channels 2, 61-78
28. Farahbakhsh, Z. T., Ridge, K. D., Khorana, H. G. & Hubbell, W. L. (1995) Biochemistry 34, 8812-8819
29. Franke, R. R., Sakmar, T. P., Graham, R. M. & Khorana, H. G. (1992) J. Biol. Chem. 267, 14767-14774
30. Almaula, N., Ebersole, B., J., Zhang, D., Weinstein, H. & Sealfon, S. C. (1996) J. Biol. Chem. 271, 14672-14675
31. Javitch, J. A., Li, X., Kaback, J. & Karlin, A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10355-10359
32. Javitch, J. A., Li, X., Fu, D., Chen, J. & Karlin, A. (1995) Neuron 14, 825-831
33. Zvyaga, T. A., Fahmy, K. & Sakmar, T. P. (1994) Biochemistry 33, 9753-9761
34. Karnik, S. S., Sakmar, T. P., Chen, H. B. & Khorana, H. G. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 8459-8463
35. Sheikh, S. P., Zvyaga, T. A., Lichtarge, O., Sakmar, T. P. & Bourne, H. R. (1996) Nature 383, 347-350
36. Farrens, D. L., Altenbach, C., Yang, K., Hubbell, W. L. & Khorana, H. G. (1996) Science 274, 768-770