Role of the C9 methyl group in rhodopsin activation: Characterization of mutant opsins with the artificial chromophore 11-cis-9-demethylretinal

Biochemistry

Volumn 37, Issue 2, 1998, Pages 538-545

  Han, May ^a   Groesbeek, Michel ^b   Smith, Steven O ^b   Sakmar, Thomas P ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b YALE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

11 CIS RETINAL; OPSIN; RHODOPSIN; 9 DEMETHYLRETINAL; 9-DEMETHYLRETINAL; DRUG DERIVATIVE; RECOMBINANT PROTEIN; RETINAL; TRANSDUCIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CHROMATOPHORE; HYDROPHOBICITY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SPECTRAL SENSITIVITY; STRUCTURE ACTIVITY RELATION; BIOLOGICAL MODEL; COMPARATIVE STUDY; GENETICS; ISOMERISM; METABOLISM; MUTATION; PHOTOLYSIS; SPECTROPHOTOMETRY;

ISOMERISM; MODELS, BIOLOGICAL; MUTATION; OPSIN; PHOTOLYSIS; RECOMBINANT PROTEINS; RETINALDEHYDE; RHODOPSIN; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSDUCIN;

EID: 0032512369     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972060w     Document Type: Article

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