-
1
-
-
17044439021
-
Alzheimer's disease: abeta, tau and synaptic dysfunction
-
LaFerla F.M., and Oddo S. Alzheimer's disease: abeta, tau and synaptic dysfunction. Trends Mol. Med. 11 (2005) 170-176
-
(2005)
Trends Mol. Med.
, vol.11
, pp. 170-176
-
-
LaFerla, F.M.1
Oddo, S.2
-
2
-
-
33745301487
-
Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance
-
Balaraman Y., et al. Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance. Cell Mol. Life Sci. 63 (2006) 1226-1235
-
(2006)
Cell Mol. Life Sci.
, vol.63
, pp. 1226-1235
-
-
Balaraman, Y.1
-
3
-
-
33750894549
-
Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease
-
Huang H.C., and Klein P.S. Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease. Curr. Drug Targets 7 (2006) 1389-1397
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 1389-1397
-
-
Huang, H.C.1
Klein, P.S.2
-
4
-
-
0038187674
-
GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
-
Phiel C.J., et al. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 423 (2003) 435-439
-
(2003)
Nature
, vol.423
, pp. 435-439
-
-
Phiel, C.J.1
-
5
-
-
0344926464
-
Divergent roles of GSK3 and CDK5 in APP processing
-
Ryder J., et al. Divergent roles of GSK3 and CDK5 in APP processing. Biochem. Biophys. Res. Commun. 312 (2003) 922-929
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.312
, pp. 922-929
-
-
Ryder, J.1
-
6
-
-
0037087220
-
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
-
Sun X., et al. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321 (2002) 61-64
-
(2002)
Neurosci. Lett.
, vol.321
, pp. 61-64
-
-
Sun, X.1
-
7
-
-
0030044463
-
Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
-
Takashima A., et al. Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta. Neurosci. Lett. 203 (1996) 33-36
-
(1996)
Neurosci. Lett.
, vol.203
, pp. 33-36
-
-
Takashima, A.1
-
8
-
-
9744238838
-
Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?
-
Chuang D.M. Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?. Crit. Rev. Neurobiol. 16 (2004) 83-90
-
(2004)
Crit. Rev. Neurobiol.
, vol.16
, pp. 83-90
-
-
Chuang, D.M.1
-
9
-
-
0036214603
-
Mood stabilizers, glycogen synthase kinase-3beta and cell survival
-
Jope R.S., and Bijur G.N. Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol. Psychiatry 7 Suppl 1 (2002) S35-S45
-
(2002)
Mol. Psychiatry
, vol.7
, Issue.SUPPL. 1
-
-
Jope, R.S.1
Bijur, G.N.2
-
10
-
-
0036810240
-
Lithium and valproic acid: parallels and contrasts in diverse signaling contexts
-
Gurvich N., and Klein P.S. Lithium and valproic acid: parallels and contrasts in diverse signaling contexts. Pharmacol. Ther. 96 (2002) 45-66
-
(2002)
Pharmacol. Ther.
, vol.96
, pp. 45-66
-
-
Gurvich, N.1
Klein, P.S.2
-
11
-
-
18444399216
-
Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
-
McManus E.J., et al. Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis. EMBO J. 24 (2005) 1571-1583
-
(2005)
EMBO J.
, vol.24
, pp. 1571-1583
-
-
McManus, E.J.1
-
12
-
-
4344619713
-
Pharmacological inhibitors of glycogen synthase kinase 3
-
Meijer L., et al. Pharmacological inhibitors of glycogen synthase kinase 3. Trends in Pharmacological Sciences 25 (2004) 471-480
-
(2004)
Trends in Pharmacological Sciences
, vol.25
, pp. 471-480
-
-
Meijer, L.1
-
13
-
-
0036273020
-
Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
-
Martinez A., et al. Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation. Med. Res. Rev. 22 (2002) 373-384
-
(2002)
Med. Res. Rev.
, vol.22
, pp. 373-384
-
-
Martinez, A.1
-
14
-
-
0029776032
-
A molecular mechanism for the effect of lithium on development
-
Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U S A 93 (1996) 8455-8459
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 8455-8459
-
-
Klein, P.S.1
Melton, D.A.2
-
15
-
-
0030449964
-
Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
-
Stambolic V., et al. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 6 (1996) 1664-1668
-
(1996)
Curr. Biol.
, vol.6
, pp. 1664-1668
-
-
Stambolic, V.1
-
16
-
-
0042379932
-
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes
-
Jope R.S. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol. Sci. 24 (2003) 441-443
-
(2003)
Trends Pharmacol. Sci.
, vol.24
, pp. 441-443
-
-
Jope, R.S.1
-
17
-
-
0042357237
-
Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
-
Zhang F., et al. Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. J. Biol. Chem. 278 (2003) 33067-33077
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33067-33077
-
-
Zhang, F.1
-
18
-
-
16844379913
-
Switching on a signaling pathway with an organoruthenium complex
-
Williams D.S., et al. Switching on a signaling pathway with an organoruthenium complex. Angew Chem. Int. Ed. Engl. 44 (2005) 1984-1987
-
(2005)
Angew Chem. Int. Ed. Engl.
, vol.44
, pp. 1984-1987
-
-
Williams, D.S.1
-
19
-
-
33646483645
-
Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease
-
Kozikowski A.P., et al. Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. Chem. Med. Chem. 1 (2006) 256-266
-
(2006)
Chem. Med. Chem.
, vol.1
, pp. 256-266
-
-
Kozikowski, A.P.1
-
20
-
-
0346875916
-
GSK-3-selective inhibitors derived from Tyrian purple indirubins
-
Meijer L., et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem. Biol. 10 (2003) 1255-1266
-
(2003)
Chem. Biol.
, vol.10
, pp. 1255-1266
-
-
Meijer, L.1
-
21
-
-
0042971809
-
Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3
-
Hongisto V., et al. Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. Mol. Cel. Biol. 23 (2003) 6027-6036
-
(2003)
Mol. Cel. Biol.
, vol.23
, pp. 6027-6036
-
-
Hongisto, V.1
-
22
-
-
0037339766
-
Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo
-
Ring D.B., et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52 (2003) 588-595
-
(2003)
Diabetes
, vol.52
, pp. 588-595
-
-
Ring, D.B.1
-
23
-
-
21044449225
-
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
-
Noble W., et al. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl. Acad. Sci. U S A 102 (2005) 6990-6995
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, pp. 6990-6995
-
-
Noble, W.1
-
24
-
-
10644255687
-
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
-
Gould T.D., et al. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int. J. Neuropsychopharmacol. 7 (2004) 387-390
-
(2004)
Int. J. Neuropsychopharmacol.
, vol.7
, pp. 387-390
-
-
Gould, T.D.1
-
25
-
-
0038811796
-
Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3
-
Plotkin B., et al. Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3. J. Pharmacol. Exp. Ther. 305 (2003) 974-980
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 974-980
-
-
Plotkin, B.1
-
26
-
-
0034969088
-
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
-
Frame S., et al. A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation. Mol. Cell 7 (2001) 1321-1327
-
(2001)
Mol. Cell
, vol.7
, pp. 1321-1327
-
-
Frame, S.1
-
27
-
-
0036909443
-
Regulation of Akt and glycogen synthase kinase-3beta phosphorylation by sodium valproate and lithium
-
De Sarno P., et al. Regulation of Akt and glycogen synthase kinase-3beta phosphorylation by sodium valproate and lithium. Neuropharmacology 43 (2002) 1158-1164
-
(2002)
Neuropharmacology
, vol.43
, pp. 1158-1164
-
-
De Sarno, P.1
-
28
-
-
33646922314
-
Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
-
Engel T., et al. Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J. Neurosci. 26 (2006) 5083-5090
-
(2006)
J. Neurosci.
, vol.26
, pp. 5083-5090
-
-
Engel, T.1
-
29
-
-
0031567583
-
Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons
-
Munoz-Montano J.R., et al. Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS Lett. 411 (1997) 183-188
-
(1997)
FEBS Lett.
, vol.411
, pp. 183-188
-
-
Munoz-Montano, J.R.1
-
30
-
-
13144265717
-
Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau
-
Takashima A., et al. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proc. Natl. Acad. Sci. U S A 95 (1998) 9637-9641
-
(1998)
Proc. Natl. Acad. Sci. U S A
, vol.95
, pp. 9637-9641
-
-
Takashima, A.1
-
31
-
-
0037145062
-
Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis
-
Kang D.E., et al. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell 110 (2002) 751-762
-
(2002)
Cell
, vol.110
, pp. 751-762
-
-
Kang, D.E.1
-
32
-
-
0033781487
-
Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons
-
Forlenza O.V., et al. Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. J. Neural Transm. 107 (2000) 1201-1212
-
(2000)
J. Neural Transm.
, vol.107
, pp. 1201-1212
-
-
Forlenza, O.V.1
-
33
-
-
0036276050
-
Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
-
Alvarez G., et al. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord. 4 (2002) 153-165
-
(2002)
Bipolar Disord.
, vol.4
, pp. 153-165
-
-
Alvarez, G.1
-
34
-
-
0032956630
-
The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
-
Chen G., et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J. Neurochem. 72 (1999) 879-882
-
(1999)
J. Neurochem.
, vol.72
, pp. 879-882
-
-
Chen, G.1
-
35
-
-
25844432119
-
Wnt signalling regulates adult hippocampal neurogenesis
-
Lie D.C., et al. Wnt signalling regulates adult hippocampal neurogenesis. Nature 437 (2005) 1370-1375
-
(2005)
Nature
, vol.437
, pp. 1370-1375
-
-
Lie, D.C.1
-
36
-
-
3342955475
-
Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
-
O'Brien W.T., et al. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J. Neurosci. 24 (2004) 6791-6798
-
(2004)
J. Neurosci.
, vol.24
, pp. 6791-6798
-
-
O'Brien, W.T.1
-
37
-
-
1842787936
-
Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
-
Beaulieu J.M., et al. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc. Natl. Acad. Sci. U S A 101 (2004) 5099-5104
-
(2004)
Proc. Natl. Acad. Sci. U S A
, vol.101
, pp. 5099-5104
-
-
Beaulieu, J.M.1
-
38
-
-
1842420631
-
Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
-
Kaidanovich-Beilin O., et al. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol. Psychiatry 55 (2004) 781-784
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 781-784
-
-
Kaidanovich-Beilin, O.1
-
39
-
-
0037220599
-
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
-
De Ferrari G.V., et al. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol. Psychiatry 8 (2003) 195-208
-
(2003)
Mol. Psychiatry
, vol.8
, pp. 195-208
-
-
De Ferrari, G.V.1
-
40
-
-
0031809141
-
Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment
-
Cohen Y., et al. Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment. Med. Oncol. 15 (1998) 32-36
-
(1998)
Med. Oncol.
, vol.15
, pp. 32-36
-
-
Cohen, Y.1
|