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Volumn 3, Issue 4, 2006, Pages 613-619

Targeting glycogen synthase kinase-3 in Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; 2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; 3 (INDOL 3 YL) 4 (1H INDAZOL 3 YL)MALEIMIDE DERIVATIVE; 6 BROMOINDIRUBIN; 6 BROMOINDIRUBIN 3' OXIME; AMYLOID BETA PROTEIN; AR A 014418; CHINESE DRUG; CHIR 98023; CHIR 99021; DANGGUI LONGHUI WAN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; GLYCOGEN SYNTHASE KINASE 3 INHIBITOR; GLYCOGEN SYNTHASE KINASE 3ALPHA; GLYCOGEN SYNTHASE KINASE 3BETA; INDIRUBIN; INDOLEMALEIMIDE DERIVATIVE; LITHIUM; LITHIUM ACETATE; LITHIUM CARBONATE; LITHIUM CHLORIDE; NP 031112; PAULLONE DERIVATIVE; RUTHENIUM; TAU PROTEIN; THIADIAZOLIDINONE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; WNT PROTEIN;

EID: 33846181973     PISSN: 17406773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddstr.2006.10.020     Document Type: Review
Times cited : (7)

References (40)
  • 1
    • 17044439021 scopus 로고    scopus 로고
    • Alzheimer's disease: abeta, tau and synaptic dysfunction
    • LaFerla F.M., and Oddo S. Alzheimer's disease: abeta, tau and synaptic dysfunction. Trends Mol. Med. 11 (2005) 170-176
    • (2005) Trends Mol. Med. , vol.11 , pp. 170-176
    • LaFerla, F.M.1    Oddo, S.2
  • 2
    • 33745301487 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance
    • Balaraman Y., et al. Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance. Cell Mol. Life Sci. 63 (2006) 1226-1235
    • (2006) Cell Mol. Life Sci. , vol.63 , pp. 1226-1235
    • Balaraman, Y.1
  • 3
    • 33750894549 scopus 로고    scopus 로고
    • Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease
    • Huang H.C., and Klein P.S. Multiple roles for glycogen synthase kinase-3 as a drug target in Alzheimer's disease. Curr. Drug Targets 7 (2006) 1389-1397
    • (2006) Curr. Drug Targets , vol.7 , pp. 1389-1397
    • Huang, H.C.1    Klein, P.S.2
  • 4
    • 0038187674 scopus 로고    scopus 로고
    • GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides
    • Phiel C.J., et al. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. Nature 423 (2003) 435-439
    • (2003) Nature , vol.423 , pp. 435-439
    • Phiel, C.J.1
  • 5
    • 0344926464 scopus 로고    scopus 로고
    • Divergent roles of GSK3 and CDK5 in APP processing
    • Ryder J., et al. Divergent roles of GSK3 and CDK5 in APP processing. Biochem. Biophys. Res. Commun. 312 (2003) 922-929
    • (2003) Biochem. Biophys. Res. Commun. , vol.312 , pp. 922-929
    • Ryder, J.1
  • 6
    • 0037087220 scopus 로고    scopus 로고
    • Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
    • Sun X., et al. Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci. Lett. 321 (2002) 61-64
    • (2002) Neurosci. Lett. , vol.321 , pp. 61-64
    • Sun, X.1
  • 7
    • 0030044463 scopus 로고    scopus 로고
    • Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta
    • Takashima A., et al. Exposure of rat hippocampal neurons to amyloid beta peptide (25-35) induces the inactivation of phosphatidyl inositol-3 kinase and the activation of tau protein kinase I/glycogen synthase kinase-3 beta. Neurosci. Lett. 203 (1996) 33-36
    • (1996) Neurosci. Lett. , vol.203 , pp. 33-36
    • Takashima, A.1
  • 8
    • 9744238838 scopus 로고    scopus 로고
    • Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?
    • Chuang D.M. Neuroprotective and neurotrophic actions of the mood stabilizer lithium: can it be used to treat neurodegenerative diseases?. Crit. Rev. Neurobiol. 16 (2004) 83-90
    • (2004) Crit. Rev. Neurobiol. , vol.16 , pp. 83-90
    • Chuang, D.M.1
  • 9
    • 0036214603 scopus 로고    scopus 로고
    • Mood stabilizers, glycogen synthase kinase-3beta and cell survival
    • Jope R.S., and Bijur G.N. Mood stabilizers, glycogen synthase kinase-3beta and cell survival. Mol. Psychiatry 7 Suppl 1 (2002) S35-S45
    • (2002) Mol. Psychiatry , vol.7 , Issue.SUPPL. 1
    • Jope, R.S.1    Bijur, G.N.2
  • 10
    • 0036810240 scopus 로고    scopus 로고
    • Lithium and valproic acid: parallels and contrasts in diverse signaling contexts
    • Gurvich N., and Klein P.S. Lithium and valproic acid: parallels and contrasts in diverse signaling contexts. Pharmacol. Ther. 96 (2002) 45-66
    • (2002) Pharmacol. Ther. , vol.96 , pp. 45-66
    • Gurvich, N.1    Klein, P.S.2
  • 11
    • 18444399216 scopus 로고    scopus 로고
    • Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
    • McManus E.J., et al. Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis. EMBO J. 24 (2005) 1571-1583
    • (2005) EMBO J. , vol.24 , pp. 1571-1583
    • McManus, E.J.1
  • 12
    • 4344619713 scopus 로고    scopus 로고
    • Pharmacological inhibitors of glycogen synthase kinase 3
    • Meijer L., et al. Pharmacological inhibitors of glycogen synthase kinase 3. Trends in Pharmacological Sciences 25 (2004) 471-480
    • (2004) Trends in Pharmacological Sciences , vol.25 , pp. 471-480
    • Meijer, L.1
  • 13
    • 0036273020 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation
    • Martinez A., et al. Glycogen synthase kinase 3 (GSK-3) inhibitors as new promising drugs for diabetes, neurodegeneration, cancer, and inflammation. Med. Res. Rev. 22 (2002) 373-384
    • (2002) Med. Res. Rev. , vol.22 , pp. 373-384
    • Martinez, A.1
  • 14
    • 0029776032 scopus 로고    scopus 로고
    • A molecular mechanism for the effect of lithium on development
    • Klein P.S., and Melton D.A. A molecular mechanism for the effect of lithium on development. Proc. Natl. Acad. Sci. U S A 93 (1996) 8455-8459
    • (1996) Proc. Natl. Acad. Sci. U S A , vol.93 , pp. 8455-8459
    • Klein, P.S.1    Melton, D.A.2
  • 15
    • 0030449964 scopus 로고    scopus 로고
    • Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
    • Stambolic V., et al. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells. Curr. Biol. 6 (1996) 1664-1668
    • (1996) Curr. Biol. , vol.6 , pp. 1664-1668
    • Stambolic, V.1
  • 16
    • 0042379932 scopus 로고    scopus 로고
    • Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes
    • Jope R.S. Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes. Trends Pharmacol. Sci. 24 (2003) 441-443
    • (2003) Trends Pharmacol. Sci. , vol.24 , pp. 441-443
    • Jope, R.S.1
  • 17
    • 0042357237 scopus 로고    scopus 로고
    • Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3
    • Zhang F., et al. Inhibitory phosphorylation of glycogen synthase kinase-3 (GSK-3) in response to lithium. Evidence for autoregulation of GSK-3. J. Biol. Chem. 278 (2003) 33067-33077
    • (2003) J. Biol. Chem. , vol.278 , pp. 33067-33077
    • Zhang, F.1
  • 18
    • 16844379913 scopus 로고    scopus 로고
    • Switching on a signaling pathway with an organoruthenium complex
    • Williams D.S., et al. Switching on a signaling pathway with an organoruthenium complex. Angew Chem. Int. Ed. Engl. 44 (2005) 1984-1987
    • (2005) Angew Chem. Int. Ed. Engl. , vol.44 , pp. 1984-1987
    • Williams, D.S.1
  • 19
    • 33646483645 scopus 로고    scopus 로고
    • Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease
    • Kozikowski A.P., et al. Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. Chem. Med. Chem. 1 (2006) 256-266
    • (2006) Chem. Med. Chem. , vol.1 , pp. 256-266
    • Kozikowski, A.P.1
  • 20
    • 0346875916 scopus 로고    scopus 로고
    • GSK-3-selective inhibitors derived from Tyrian purple indirubins
    • Meijer L., et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem. Biol. 10 (2003) 1255-1266
    • (2003) Chem. Biol. , vol.10 , pp. 1255-1266
    • Meijer, L.1
  • 21
    • 0042971809 scopus 로고    scopus 로고
    • Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3
    • Hongisto V., et al. Lithium blocks the c-Jun stress response and protects neurons via its action on glycogen synthase kinase 3. Mol. Cel. Biol. 23 (2003) 6027-6036
    • (2003) Mol. Cel. Biol. , vol.23 , pp. 6027-6036
    • Hongisto, V.1
  • 22
    • 0037339766 scopus 로고    scopus 로고
    • Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo
    • Ring D.B., et al. Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52 (2003) 588-595
    • (2003) Diabetes , vol.52 , pp. 588-595
    • Ring, D.B.1
  • 23
    • 21044449225 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo
    • Noble W., et al. Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo. Proc. Natl. Acad. Sci. U S A 102 (2005) 6990-6995
    • (2005) Proc. Natl. Acad. Sci. U S A , vol.102 , pp. 6990-6995
    • Noble, W.1
  • 24
    • 10644255687 scopus 로고    scopus 로고
    • AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
    • Gould T.D., et al. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. Int. J. Neuropsychopharmacol. 7 (2004) 387-390
    • (2004) Int. J. Neuropsychopharmacol. , vol.7 , pp. 387-390
    • Gould, T.D.1
  • 25
    • 0038811796 scopus 로고    scopus 로고
    • Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3
    • Plotkin B., et al. Insulin mimetic action of synthetic phosphorylated peptide inhibitors of glycogen synthase kinase-3. J. Pharmacol. Exp. Ther. 305 (2003) 974-980
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 974-980
    • Plotkin, B.1
  • 26
    • 0034969088 scopus 로고    scopus 로고
    • A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation
    • Frame S., et al. A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation. Mol. Cell 7 (2001) 1321-1327
    • (2001) Mol. Cell , vol.7 , pp. 1321-1327
    • Frame, S.1
  • 27
    • 0036909443 scopus 로고    scopus 로고
    • Regulation of Akt and glycogen synthase kinase-3beta phosphorylation by sodium valproate and lithium
    • De Sarno P., et al. Regulation of Akt and glycogen synthase kinase-3beta phosphorylation by sodium valproate and lithium. Neuropharmacology 43 (2002) 1158-1164
    • (2002) Neuropharmacology , vol.43 , pp. 1158-1164
    • De Sarno, P.1
  • 28
    • 33646922314 scopus 로고    scopus 로고
    • Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3
    • Engel T., et al. Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3. J. Neurosci. 26 (2006) 5083-5090
    • (2006) J. Neurosci. , vol.26 , pp. 5083-5090
    • Engel, T.1
  • 29
    • 0031567583 scopus 로고    scopus 로고
    • Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons
    • Munoz-Montano J.R., et al. Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons. FEBS Lett. 411 (1997) 183-188
    • (1997) FEBS Lett. , vol.411 , pp. 183-188
    • Munoz-Montano, J.R.1
  • 30
    • 13144265717 scopus 로고    scopus 로고
    • Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau
    • Takashima A., et al. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proc. Natl. Acad. Sci. U S A 95 (1998) 9637-9641
    • (1998) Proc. Natl. Acad. Sci. U S A , vol.95 , pp. 9637-9641
    • Takashima, A.1
  • 31
    • 0037145062 scopus 로고    scopus 로고
    • Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis
    • Kang D.E., et al. Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis. Cell 110 (2002) 751-762
    • (2002) Cell , vol.110 , pp. 751-762
    • Kang, D.E.1
  • 32
    • 0033781487 scopus 로고    scopus 로고
    • Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons
    • Forlenza O.V., et al. Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. J. Neural Transm. 107 (2000) 1201-1212
    • (2000) J. Neural Transm. , vol.107 , pp. 1201-1212
    • Forlenza, O.V.1
  • 33
    • 0036276050 scopus 로고    scopus 로고
    • Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease
    • Alvarez G., et al. Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. Bipolar Disord. 4 (2002) 153-165
    • (2002) Bipolar Disord. , vol.4 , pp. 153-165
    • Alvarez, G.1
  • 34
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G., et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J. Neurochem. 72 (1999) 879-882
    • (1999) J. Neurochem. , vol.72 , pp. 879-882
    • Chen, G.1
  • 35
    • 25844432119 scopus 로고    scopus 로고
    • Wnt signalling regulates adult hippocampal neurogenesis
    • Lie D.C., et al. Wnt signalling regulates adult hippocampal neurogenesis. Nature 437 (2005) 1370-1375
    • (2005) Nature , vol.437 , pp. 1370-1375
    • Lie, D.C.1
  • 36
    • 3342955475 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium
    • O'Brien W.T., et al. Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J. Neurosci. 24 (2004) 6791-6798
    • (2004) J. Neurosci. , vol.24 , pp. 6791-6798
    • O'Brien, W.T.1
  • 37
    • 1842787936 scopus 로고    scopus 로고
    • Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
    • Beaulieu J.M., et al. Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade. Proc. Natl. Acad. Sci. U S A 101 (2004) 5099-5104
    • (2004) Proc. Natl. Acad. Sci. U S A , vol.101 , pp. 5099-5104
    • Beaulieu, J.M.1
  • 38
    • 1842420631 scopus 로고    scopus 로고
    • Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus
    • Kaidanovich-Beilin O., et al. Rapid antidepressive-like activity of specific glycogen synthase kinase-3 inhibitor and its effect on beta-catenin in mouse hippocampus. Biol. Psychiatry 55 (2004) 781-784
    • (2004) Biol. Psychiatry , vol.55 , pp. 781-784
    • Kaidanovich-Beilin, O.1
  • 39
    • 0037220599 scopus 로고    scopus 로고
    • Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils
    • De Ferrari G.V., et al. Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils. Mol. Psychiatry 8 (2003) 195-208
    • (2003) Mol. Psychiatry , vol.8 , pp. 195-208
    • De Ferrari, G.V.1
  • 40
    • 0031809141 scopus 로고    scopus 로고
    • Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment
    • Cohen Y., et al. Cancer morbidity in psychiatric patients: influence of lithium carbonate treatment. Med. Oncol. 15 (1998) 32-36
    • (1998) Med. Oncol. , vol.15 , pp. 32-36
    • Cohen, Y.1


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