Platelet-mediated regulation of immunity;Płytki krwi jako regulatory procesów odpornos̈ciowych

Postepy Higieny i Medycyny Doswiadczalnej

Volumn 60, Issue , 2006, Pages 265-277

  Wazna, Ewa ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Immunity; Inflammatory; Neoplastic disease; Platelet derived microvesicles (PMV); Platelet microparticles (PMP); Platelets

Indexed keywords

MEMBRANE PROTEIN; P SELECTIN LIGAND PROTEIN; P-SELECTIN LIGAND PROTEIN; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL; APOPTOSIS; ATHEROSCLEROSIS; BLOOD; HEMATOPOIESIS; HUMAN; IMMUNOLOGY; INFLAMMATION; METABOLISM; METASTASIS; NEOPLASM; REVIEW; THROMBOCYTE; VASCULAR ENDOTHELIUM;

ANIMALS; APOPTOSIS; ATHEROSCLEROSIS; BLOOD PLATELETS; ENDOTHELIUM, VASCULAR; ENGLISH ABSTRACT; HEMATOPOIESIS; HUMANS; INFLAMMATION; MEMBRANE GLYCOPROTEINS; NEOPLASM METASTASIS; NEOPLASMS; TOLL-LIKE RECEPTORS;

EID: 33846117676     PISSN: 00325449     EISSN: 17322693     Source Type: Journal    
DOI: None     Document Type: Review

References (147)

1. Abreu M.T., Thomas L.S., Arnold E.T., Lukasek K., Michelsen K.S., Arditi M.: TLR signaling at the intestinal epithelial interface. J. Endotoxin. Res., 2003; 9: 322-330
2. Amirkhosravi A., Alexander M., May K., Francis D.A., Warnes G., Biggerstaff J., Francis J.L.: The importance of platelets in the expression of monocyte tissue factor antigen measured by a new whole blood flow cytometric assay. Thromb. Haemost., 1996; 75: 87-95
3. Andonegui G., Kerfoot S.M., McNagny K., Ebbert K.V., Patel K.D., Kubes P.: Platelets express functional Toll-like receptor-4. Blood, 2005; 106: 2417-2423
4. Baj-Krzyworzeka M., Majka M., Pratico D., Ratajczak J., Vilaire G., Kijowski J., Reca R., Janowska-Wieczorek A., Ratajczak M.Z.: Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells. Exp. Hematol., 2002; 30: 450-459
5. Bakewell S.J., Nestor P., Prasad S., Tomasson M.H., Dowland N., Mehrotra M., Scarborough R., Kanter J., Abe K., Phillips D., Weilbaecher K.N.: Platelet and osteoclast beta3 integrins are critical for bone metastasis. Proc. Natl. Acad. Sci. USA, 2003; 100: 14205-14210
6. Bargatze R.F., Kurk S., Butcher E.C., Jutila M.A.: Neutrophils roll on adherent neutrophils bound to cytokine-induced endothelial cells via L-selectin on the rolling cells. J. Exp. Med., 1994; 180: 1785-1792
7. Barry O.P., FitzGerald G.A.: Mechanisms of cellular activation by platelet microparticles. Thromb. Haemost., 1999; 82: 794-800
8. Barry O.P., Kazanietz M.G., Pratico D., FitzGerald G.A.: Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathway. J. Biol. Chem., 1999; 274: 7545-7556
9. Barry O.P., Pratico D., Lawson J.A., FitzGerald G.A.: Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles. J. Clin. Invest., 1997; 99: 2118-2127
10. Barry O.P., Pratico D., Savani R.C., FitzGerald G.A.: Modulation of monocyte-endothelial cell interactions by platelet microparticles. J. Clin. Invest., 1998; 102: 136-144
11. Beaudoin A.R., Grondin G.: Shedding of vesicular material from the cell surface of eukaryotic cell: different cellular phenomena. Biochim. Biophys. Acta, 1991; 1071: 203-219
12. Berndt M.C., Shen Y., Dopheide S.M., Gardiner E.E., Andrews R.K.: The vascular biology of the glycoprotein Ib-IX-V complex. Thromb. Haemost., 2001; 86: 178-188
13. Bode A.P., Hickerson D.H.: Characterization and quantitation by flow cytometry of membranous microparticles formed during activation of platelet suspensions with ionophore or thrombin. Platelets, 2000; 11: 259-271
14. Brash A.R.: Arachidonic acid as a bioactive molecule. J. Clin. Invest., 2001; 107: 1339-1345
15. Brinckerhoff C.E., Matrisian L.M.: Matrix metalloproteinases: A tail of a frog that became a prince. Nat. Rev. Mol. Cell. Biol., 2002; 3: 207-214
16. Brooks P.C., Clark R.A., Cheresh D.A.: Requirement of vascular integrin alpha v beta 3 for angiogenesis. Science, 1994; 264: 569-571
17. Camera M., Frigerio M., Toschi V., Brambilla M., Rossi F., Cottell D.C., Maderna P., Parolari A., Bonzi R., De Vincenti O., Tremoli E.: Platelet activation induces cell-surface immunoreactive tissue factor expression, which is modulated differently by antiplatelet drugs. Arterioscler. Thromb. Vasc. Biol., 2003; 23: 1690-1696
18. Camerer E., Kolsto A.B., Prydz H.: Cell biology of tissue factor, the principal initiator of blood coagulation. Thromb. Res., 1996; 81: 1-41
19. Carty E., MacEy M., Rampton D.S.: Inhibition of platelet activation by 5-aminosalicylic acid in inflammatory bowel disease. Aliment. Pharmacol. Ther., 2000; 14: 1169-1179
20. Celi A., Pellegrini G., Lorenzet R., De Blasi A., Ready N., Furie B.C., Furie B.: P-selectin induces the expression of tissue factor on monocytes. Proc. Natl. Acad. Sci. USA, 1994; 91: 8767-8771
21. Chew D.P., Bhatt D.L., Sapp S., Topol E.J.: Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: A meta-analysis of phase III multicenter randomized trials. Circulation, 2001; 103: 201-206
22. Chuang T., Ulevitch R.J.: Identification of hTLR10: A novel human Toll-like receptor preferentially expressed in immune cells. Biochim. Biophys. Acta., 2001; 1518: 157-161
23. Cognasse F., Hamzeh H., Chavarin P., Acquart S., Genin C., Garraud O.: Evidence of Toll-like receptor molecules on human platelets. Immunol. Cell. Biol., 2005; 83: 196-198
24. Coleman R.E.: Future directions in the treatment and prevention of bone metastases. Am. J. Clin. Oncol., 2002; 25(Suppl.1): S32-S38
25. Collins C.E., Cahill M.R., Newland A.C., Rampton D.S.: Platelets circulate in an activated state in inflammatory bowel disease. Gastroenterology, 1994; 106: 840-845
26. Combes V., Simon A.C., Grau G.E., Arnoux D., Camoin L., Sabatier F., Mutin M., Sanmarco M., Sampol J., Dignat-George F.: In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant. J. Clin. Invest., 1999;104: 93-102
27. Dainiak N.: Surface membrane-associated regulation of cell assembly, differentiation, and growth. Blood, 1991; 78: 264-276
28. Denzer K., Kleijmeer M.J., Heijnen H.F., Stoorvogel W., Geuze H.J.: Exosome: from internal vesicle of the multivesicular body to intercellular signaling device. J. Cell. Sci., 2000; 19: 3365-3374
29. Egeblad M., Werb Z.: New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer., 2002; 2: 161-174
30. Elzey B.D., Grant J.F., Sinn H.W., Nieswandt B., Waldschmidt T.J., Ratliff T.L.: Cooperation between platelet-derived CD154 and CD4+ T cells for enhanced germinal center formation. J. Leukoc. Biol., 2005; 78: 80-84
31. Elzey B.D., Tian J., Jensen R.J., Swanson A.K., Lees J.R., Lentz S.R., Stein C.S., Nieswandt B., Wang Y., Davidson B.L., Ratliff T.L.: Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments. Immunity, 2003; 19: 9-19
32. English D., Garcia J.G., Brindley D.N.: Platelet-released phospholipids link haemostasis and angiogenesis. Cardiovasc. Res., 2001; 49: 588-599
33. English D., Welch Z., Kovala A.T., Harvey K., Volpert O.V., Brindley D.N., Garcia J.G.: Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between hemostasis and angiogenesis. FASEB J., 2000; 14: 2255-2265
34. Escola J.M., Kleijmeer M.J., Stoorvogel W., Griffith J.M., Yoshie O., Geuze H.J.: Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes. J. Biol. Chem., 1998; 273: 20121-20127
35. Esmon C.T.: Inflammation and thrombosis. J. Thromb. Haemost., 2003; 1: 1343-1348
36. Evangelista V., Manarini S., Sideri R., Rotondo S., Martelli N., Piccoli A., Totani L., Piccardoni P., Vestweber D., de Gaetano G., Cerletti C.: Platelet/polymorphonuclear leukocyte interaction: P-selectin triggers protein-tyrosine phosphorylation-dependent CD11b/CD18 adhesion: role of PSGL-1 as a signaling molecule. Blood, 1999; 93: 876-885
37. Evangelista V., Rajtar G., de Gaetano G., White J.G., Cerletti C.: Platelet activation by fMLP-stimulated polymorphonuclear leukocytes: The activity of cathepsin G is not prevented by antiproteinases. Blood, 1991; 77: 2379-2388
38. Feng X., Novack D.V., Faccio R., Ory D.S., Aya K., Boyer M.I., McHugh K.P., Ross F.P., Teitelbaum S.L.: A Glanzmann's mutation in beta 3 integrin specifically impairs osteoclast function. J. Clin. Invest., 2001; 107: 1137-1144
39. Francis J.L., Amirkhosravi A.: Effect of antihemostatic agents on experimental tumor dissemination. Semin. Thromb. Hemost., 2002; 28: 29-38
40. Forlow S.B., McEver R.P., Nollert M.U.: Leukocyte-leukocyte interactions mediated by platelet microparticles under flow. Blood, 2000; 95: 1317-1323
41. Furie B., Furie B.C.: P-selectin induction of tissue factor biosynthesis and expression. Haemostasis, 1996; 26(Suppl.1): 60-65
42. Furie B., Furie B.C.: The molecular basis of platelet and endothelial cell interaction with neutrophils and monocytes: role of P-selectin and the P-selectin ligand, PSGL-1. Thromb. Haemost., 1995; 74: 224-227
43. Furman M.I., Barnard M.R., Krueger L.A., Fox M.L., Shilale E.A., Lessard D.M., Marchese P., Frelinger A.L. III, Michelson A.D.: Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction. J. Am. Coll. Cardiol., 2001; 38: 1002-1006
44. Furman M.I., Benoit S.E., Barnard M.R., Valeri C.R., Borbone M.L., Becker R.C., Hechtman H.B., Michelson A.D.: Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J. Am. Coll. Cardiol., 1998; 31: 352-358
45. Gawaz M., Fateh-Moghadam S., Pilz G., Gurland H.J., Werdan K.: Platelet activation and interaction with leucocytes in patients with sepsis or multiple organ failure. Eur. J. Clin. Invest., 1995; 25: 843-851
46. Gawaz M.P., Mujais S.K., Schmidt B., Gurland H.J.: Platelet-leukocyte aggregation during hemodialysis. Kidney Int., 1994; 46: 489-495
47. Geng J.G., Moore K.L., Johnson A.E., McEver R.P.: Neutrophil recognition requires a Ca(2+)-induced conformational change in the lectin domain of GMP-140. J. Biol. Chem., 1991; 266: 22313-22318
48. George J.N., Thoi L.L., McManus L.M., Reimann T.A.: Isolation of human platelet membrane microparticles from plasma and serum. Blood, 1982; 60: 834-840
49. Ginestra A., Miceli D., Dolo V., Romano F.M., Vittorelli M.L.: Membrane vesicles in ovarian cancer fluids: A new potential marker. Anticancer Res., 1999; 19: 3439-3445
50. Harries A.D., Fitzsimons.E, Fifield R., Dew M.J., Rhoades J.: Platelet count: A simple measure of activity in Crohn's disease. Br. Med. J., 1983; 286: 1476
51. Heijnen H.F., Schiel A.E., Fijnheer R., Geuze H.J., Sixma J.J.: Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules. Blood,1999; 94: 3791-3799
52. Hodivala-Dilke K.M., McHugh K.P., Tsakiris D.A., Rayburn H., Crowley D., Ullman-Cullere M., Ross F.P., Coller B.S., Teitelbaum S., Hynes R.O.: Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J. Clin. Invest., 1999;103: 229-238
53. Honn K.V., Tang D.G., Chen Y.Q.: Platelets and cancer metastasis: more than an epiphenomenon. Semin. Thromb. Hemost., 1992; 18: 392-415
54. Hood J.D., Cheresh D.: A role of integrins in cell invasion and migration. Nat. Rev. Cancer, 2002; 2: 91-100
55. Hornef M.W., Normark B.H., Vandewalle A., Normark S.: Intracellular recognition of lipopolysaccharide by toll-like receptor 4 in intestinal epithelial cells. J. Exp. Med., 2003; 198: 1225-1235
56. Hrachovinova I., Cambien B., Hafezi-Moghadam A., Kappelmayer J., Camphausen R.T., Widom A., Xia L., Kazazian H.H. Jr, Schaub R.G., McEver R.P., Wagner D.D.: Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A. Nat. Med., 2003; 9: 1020-1025
57. Hugel B., Socie G., Vu T., Toti F., Gluckman E., Freyssinet J.M., Scrobohaci M.L.: Elevated levels of circulating procoagulant microparticles in patients with paroxysmal nocturnal hemoglobinuria and aplastic anemia. Blood. 1999; 93: 3451-3456
58. Hughes M., Hayward C.P., Warkentin T.E., Horsewood P., Chorneyko K.A., Kelton J.G.: Morphological analysis of microparticle generation in heparin-induced thrombocytopenia. Blood, 2000; 96: 188-194
59. Hynes R.O.: Integrins: bidirectional, allosteric signaling machines. Cell, 2002; 110: 673-687
60. Iannacone M., Sitia G., Isogawa M., Marchese P., Castro M.G., Lowenstein P.R., Chisari F.V., Ruggeri Z.M., Guidotti L.G.: Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nat. Med., 2005; 11: 1167-1169
61. Imler J.L., Hoffmann J.A.: Toll receptors in innate immunity. Trends Cell. Biol., 2001; 11: 304-311
62. Irving P.M., Macey M.G., Shah U., Webb L., Langmead L., Rampton D.S.: Formation of platelet-leukocyte aggregates in inflammatory bowel disease. Inflamm. Bowel Dis., 2004; 10: 361-372
63. Janowska-Wieczorek A., Majka M., Kijowski J., Baj-Krzyworzeka M., Reca R., Turner A.R., Ratajczak J., Emerson S.G., Kowalska M.A., Ratajczak M.Z.: Platelet-derived microparticles bind to hematopoietic stem/progenitor cells and enhance their engraftment. Blood, 2001; 98: 3143-3149
64. Janowska-Wieczorek A., Wysoczynski M., Kijowski J., Marquez-Curtis L., Machalinski B., Ratajczak J., Ratajczak MZ.: Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer. Int. J. Cancer., 2005; 113: 752-760
65. Jaremo P., Sandberg-Gertzen H.: Platelet density and size in inflammatory bowel disease. Thromb. Haemost., 1996; 75: 560-561
66. Jimenez J.J., Jy W., Mauro L.M., Horstman L.L., Ahn Y.S.: Elevated endothelial microparticles in thrombotic thrombocytopenic purpura: findings from brain and renal microvascular cell culture and patients with active disease. Br. J. Haematol., 2001;112: 81-90
67. Joseph J.E., Harrison P., Mackie I.J., Isenberg D.A., Machin S.J.: Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis. Br. J. Haematol., 2001; 115: 451-459
68. Jungi T.W., Spycher M.O., Nydegger U.E., Barandun S.: Platelet-leukocyte interaction: selective binding of thrombin-stimulated platelets to human monocytes, polymorphonuclear leukocytes, and related cell lines. Blood, 1986; 67: 629-636
69. Kaplar M., Kappelmayer J., Kiss A., Szabo K., Udvardy M.: Increased leukocyte-platelet adhesion in chronic myeloproliferative disorders with high platelet counts. Platelets, 2000; 11: 183-184
70. Kapsoritakis A.N., Koukourakis M.I., Sfiridaki A., Potamianos S.P., Kosmadaki M.G., Koutroubakis I.E., Kouroumalis E.A.: Mean platelet volume: A useful marker of inflammatory bowel disease activity. Am. J. Gastroenterol., 2001; 96: 776-781
71. Karpatkin S., Pearlstein E., Ambrogio C., Coller B.S.: Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo. J. Clin. Invest., 1988; 81: 1012-1019
72. Koga H., Sugiyama S., Kugiyama K., Watanabe K., Fukushima H., Tanaka T., Sakamoto T., Yoshimura M., Jinnouchi H., Ogawa H.: Elevated levels of VE-cadherin-positive endothelial microparticles in patients with type 2 diabetes mellitus and coronary artery disease. J. Am. Coll. Cardiol., 2005; 45: 1622-1630
73. Kuijper P.H., Gallardo Tores H.I., Lammers J.W., Sixma J.J., Koenderman L., Zwaginga J.J.: Platelet associated fibrinogen and ICAM-2 induce firm adhesion of neutrophils under flow conditions. Thromb. Haemost., 1998; 804: 443-448
74. Kurose I., Granger D.N., Evans D.J. Jr, Evans D.G., Graham D.Y., Miyasaka M., Anderson D.C., Wolf R.E., Cepinskas G., Kvietys P.R.: Helicobacter pylori-induced microvascular protein leakage in rats: role of neutrophils, mast cells, and platelets. Gastroenterology, 1994; 107: 70-79
75. Kurose I., Pothoulakis C., LaMont J.T., Anderson D.C., Paulson J.C., Miyasaka M., Wolf R., Granger D.N.: Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine. J. Clin. Invest.,1994; 94: 1919-1926
76. Leatham E.W., Bath P.M., Tooze J.A., Camm A.J.: Increased monocyte tissue factor expression in coronary disease. Br. Heart J. 1995; 73: 10-13
77. Lehr H.A., Weyrich A.S., Saetzler R.K., Jurek A., Arfors K.E., Zimmerman G.A., Prescott S.M., McIntyre T.M.: Vitamin C blocks inflammatory platelet-activating factor mimetics created by cigarette smoking. J. Clin. Invest.,1997; 99: 2358-2364
78. Li N., Goodall A.H., Hjemdahl P.: A sensitive flow cytometric assay for circulating platelet-leucocyte aggregates. Br. J. Haematol., 1997; 99: 808-816
79. Li N., Goodall A.H., Hjemdahl P.: Efficient flow cytometric assay for platelet-leukocyte aggregates in whole blood using fluorescence signal triggering. Cytometry, 1999; 35: 154-161
80. Li N., Wallen N.H., Hjemdahl P.: Evidence for prothrombotic effects of exercise and limited protection by aspirin. Circulation, 1999; 100: 1374-1379
81. Lindmark E., Tenno T., Siegbahn A.: Role of platelet P-selectin and CD40 ligand in the induction of monocytic tissue factor expression. Arterioscler Thromb Vasc Biol., 2000; 20: 2322-2328
82. Lösche W., Scholz T., Temmler U., Oberle V., Claus R.A.: Platelet-derived microvesicles transfer tissue factor to monocytes but not to neutrophils. Platelets, 2004; 15: 109-115
83. Macey M., Azam U., McCarthy D., Webb L., Chapman E.S., Okrongly D., Zelmanovic D., Newland A.: Evaluation of the anticoagulants EDTA and citrate, theophylline, adenosine, and dipyridamole (CTAD) for assessing platelet activation on the ADVIA 120 hematology system. Clin. Chem., 2002; 48: 891-899
84. Maugeri N., Evangelista V., Celardo A., Dell'Elba G., Martelli N., Piccardoni P., de Gaetano G., Cerletti C.: Polymorphonuclear leukocyte-platelet interaction: role of P-selectin in thromboxane B2 and leukotriene C4 cooperative synthesis. Thromb. Haemost., 1994; 72: 450-456
85. McCarty O.J., Mousa S.A., Bray P.F., Konstantopoulos K.: Immobilized platelets support human colon carcinoma cell tethering, rolling, and firm adhesion under dynamic flow conditions. Blood, 2000; 96: 1789-1797
86. McHugh K.P., Hodivala-Dilke K., Zheng M.H., Namba N., Lam J., Novack D., Feng X., Ross F.P., Hynes R.O., Teitelbaum S.L.: Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. J. Clin. Invest., 2000; 105: 433-440
87. Mesri M., Altieri D.C.: Leukocyte microparticles stimulate endothelial cell cytokine release and tissue factor induction in a JNK1 signaling pathway. J. Biol. Chem., 1999; 274: 23111-23118
88. Michelson A.D., Furman M.I.: Laboratory markers of platelet activation and their clinical significance. Curr. Opin. Hematol., 1999; 6: 342-348
89. Mickelson J.K., Lakkis N.M., Villarreal-Levy G., Hughes B.J., Smith C.W.: Leukocyte activation with platelet adhesion after coronary angioplasty: A mechanism for recurrent disease? J. Am. Coll. Cardiol., 1996; 28: 345-353
90. Miyamoto S., Kowalska M.A., Marcinkiewicz C., Marcinkiewicz M.M., Mosser D., Edmunds L.H. Jr., Niewiarowski S.: Interaction of leukocytes with platelet microparticles derived from outdated platelet concentrates. Thromb. Haemost., 1998; 80: 982-988
91. Miyamoto S., Marcinkiewicz C., Edmunds L.H. Jr., Niewiarowski S.: Measurement of platelet microparticles during cardiopulmonary bypass by means of captured ELISA for GPIIb/IIIa. Thromb. Haemost., 1998; 80: 225-230
92. Montrucchio G., Bosco O., Del Sorbo L., Fascio Pecetto P., Lupia E., GoffiA., Omede P., Emanuelli G., Camussi G.: Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole blood. Thromb. Haemost., 2003; 90: 872-881
93. Morales-Ruiz M., Lee M.J., Zollner S., Gratton J.P., Scotland R., Shiojima I., Walsh K., Hla T., Sessa W.C.: Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Gi protein/phosphoinositide 3-kinase pathway in endothelial cells. J. Biol. Chem., 2001; 276: 19672-19677
94. Morowitz D.A., Allen L.W., Kirsner J.B.: Thrombocytosis in chronic inflammatory bowel disease. Ann. Intern. Med., 1968; 68: 1013-1110
95. Muzio M., Bosisio D., Polentarutti N., D'Amico G., Stoppacciaro A., Mancinelli R., van't Veer C., Penton-Rol G., Ruco L.P., Allavena P., Mantovani A.: Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J. Immunol., 2000; 164: 5998-6021
96. Nash G.F., Turner L.F., Scully M.F., Kakkar A.K.: Platelets and cancer. Lancet Oncol., 2002; 3: 425-430
97. Nawrocki B., Polette M., Marchand V., Monteau M., Gillery P., Tournier J.M., Birembaut P.: Expression of matrix metalloproteinases and their inhibitors in human bronchopulmonary carcinomas: quantificative and morphological analyses. Int. J. Cancer., 1997; 72: 556-564
98. Neumann F.J., Marx N., Gawaz M., Brand K., Ott I., Rokitta C., Sticherling C., Meinl C., May A., Schomig A.: Induction of cytokine expression in leukocytes by binding of thrombin-stimulated platelets. Circulation, 1997; 95: 2387-2394
99. Nieuwland R., Berckmans R.J., McGregor S., Boing A.N., Romijn F.P., Westendorp R.G., Hack C.E., Sturk A.: Cellular origin and procoagulant properties of microparticles in meningococcal sepsis. Blood, 2000; 95: 930-935
100. Osterud B., Rao L.V., Olsen J.O.: Induction of tissue factor expression in whole blood: lack of evidence for the presence of tissue factor expression in granulocytes. Thromb. Haemost., 2000; 83: 861-867
101. Ott I., Neumann F.J., Gawaz M., Schmitt M., Schomig A.: Increased neutrophil-platelet adhesion in patients with unstable angina. Circulation, 1996; 94: 1239-1246
102. Page C.P.: Platelets as inflammatory cells. Immunopharmacology, 1989; 17: 51-59
103. Palecanda A., Walcheck B., Bishop D.K., Jutila M.A.: Rapid activation-independent shedding of leukocyte L-selectin induced by cross-linking of the surface antigen. Eur. J. Immunol., 1992; 22: 1279-1286
104. Pearlstein E., Ambrogio C., Karpatkin S.: Effect of antiplatelet antibody on the development of pulmonary metastases following injection of CT26 colon adenocarcinoma, Lewis lung carcinoma, and B16 amelanotic melanoma tumor cells into mice. Cancer Res., 1984; 44: 3884-3887
105. Peters M.J., Dixon G., Kotowicz K.T., Hatch D.J., Heyderman R.S., Klein N.J.: Circulating platelet-neutrophil complexes represent a subpopulation of activated neutrophils primed for adhesion, phagocytosis and intracellular killing. Br. J. Haematol., 1999; 106: 391-399
106. Peters M.J., Heyderman R.S., Hatch D.J., Klein N.J.: Investigation of platelet-neutrophil interactions in whole blood by flow cytometry. J. Immunol. Methods, 1997; 209: 125-135
107. Pivarcsi A., Bodai L., Rethi B., Kenderessy-Szabo A., Koreck A., Szell M., Beer Z., Bata-Csorgoo Z., Magocsi M., Rajnavolgyi E., Dobozy A., Kemeny L.: Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int. Immunol., 2003; 15: 721-730
108. Renshaw B.R., Fanslow W.C. III, Armitage R.J., Campbell K.A.,Liggitt D., Wright B., Davison B.L., Maliszewski C.R.: Humoral immune responses in CD40 ligand-deficient mice. J. Exp. Med., 1994; 180: 1889-1900
109. Rinder C.S., Bonan J.L., Rinder H.M., Mathew J., Hines R., Smith B.R.: Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood, 1992; 79: 1201-1205
110. Rinder H.M., Bonan L., Rinder C.S., Ault K.A., Smith B.R.: Dynamics of leukocyte-platelet adhesion in whole blood. Blood, 1991; 78: 1730-1737
111. Rinder H.M., Tracey J.L., Rinder C.S., Leitenberg D., Smith B.R.: Neutrophil but not monocyte activation inhibits P-selectin-mediated platelet adhesion. Thromb. Haemost., 1994; 72: 750-756
112. Rozmyslowicz T., Majka M., Kijowski J., Gaulton G.N., Ratajczak M.Z.: A new role of platelet-and megakaryocyte-derived microparticles (MP) in HIV infection. Blood, 2001; 98: 786a
113. Rozmyslowicz T., Majka M., Kijowski J., Murphy S.L., Conover D.O., Poncz M., Ratajczak J., Gaulton G.N., Ratajczak M.Z.: Plateletand megakaryocyte-derived microparticles transfer CXCR4 receptor to CXCR4-null cells and make them susceptible to infection by X4-HIV. AIDS, 2003; 17: 33-42
114. Sabatier F., Roux V., Anfosso F., Camoin L., Sampol J., Dignat-George F.: Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activity. Blood, 2002; 99: 3962-3970
115. Sabroe I., Jones E.C., Usher L.R., Whyte M.K., Dower S.K.: Tolllike receptor (TLR)2 and TLR4 in human peripheral blood granulocytes: A critical role for monocytes in leukocyte lipopolysaccharide responses. J. Immunol., 2002; 168: 4701-4710
116. Salaj P., Marinov I., Markova M., Pohlreich D., Cetkovsky P., Hrachovinova I.: Thrombelastography monitoring of platelet substitution therapy and rFVIIa administration in haemato-oncological patients with severe thrombocytopenia. Prague Med. Rep., 2004; 105: 311-317
117. Sarma J., Laan C.A., Alam S., Jha A., Fox K.A., Dransfield I.: Increased platelet binding to circulating monocytes in acute coronary syndromes. Circulation, 2002; 105: 2166-2171
118. Scholz T., Temmler U., Krause S., Heptinstall S., Losche W.: Transfer of tissue factor from platelets to monocytes: role of platelet-derived microvesicles and CD62P. Thromb. Haemost., 2002; 88: 1033-1038
119. Seiki M.: Membrane-type 1matrix metalloproteinase: A key enzyme for tumor invasion. Cancer Lett., 2003; 194: 1-11
120. Siddiqui F.A., Desai H., Amirkhosravi A., Amaya M., Francis J.L.: The presence and release of tissue factor from human platelets. Platelets. 2002; 13: 247-253
121. Solum N.O.: Procoagulant expression in platelets and defects leading to clinical disorders.Arterioscler. Thromb. Vasc. Biol., 1999; 19: 2841-2846
122. Spangenberg P., Redlich H., Bergmann I., Losche W., Gotzrath M., Kehrel B.: The platelet glycoprotein IIb/IIIa complex is involved in the adhesion of activated platelets to leukocytes. Thromb. Haemost., 1993; 70: 514-521
123. Suefuji H., Ogawa H, Yasue H., Kaikita K., Soejima H., Motoyama T., Mizuno Y., Oshima S., Saito T., Tsuji I., Kumeda K., Kamikubo Y., Nakamura S.: Increased plasma tissue factor levels in acute myocardial infarction. Am. Heart J., 1997; 134: 253-259
124. Surette M.E., Fonteh A.N., Bernatchez C., Chilton F.H.: Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells. Carcinogenesis, 1999; 20: 757-763
125. Takeda K., Kaisho T., Akira S.: Toll-like receptors. Annu. Rev. Immunol., 2003; 21: 335-376
126. Tan K.T, Lip G.Y.: The potential role of platelet microparticles in atherosclerosis. Thromb. Haemost., 2005; 94: 488-492
127. Taucher S., Salat A., Gnant M., Kwasny W., Mlineritsch B., Menzel R.C., Schmid M., Smola M.G., Stierer M., Tausch C., Galid A., Steger G., Jakesz R., Austrian Breast and Colorectal Cancer Study Group: Impact of pretreatment thrombocytosis on survival in primary breast cancer. Thromb. Haemost., 2003; 89: 1098-1106
128. Tavener S.A., Long E.M., Robbins S.M., McRae K.M., Van Remmen H., Kubes P.: Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. Circ. Res., 2004; 95: 700-707
129. Thomas G., Skrinska V.A., Lucas F.V.: The influence of glutathione and other thiols on human platelet aggregation. Thromb. Res., 1986; 44: 859-866
130. Tokuraku M., Sato H., Murakami S., Okada Y., Watanabe Y., Seiki M.: Activation of the precursor of gelatinase A/72 kDa type IV collagenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase (MT-MMP) and with lymph node metastasis. Int. J. Cancer., 1995; 64: 355-359
131. Tsuji T., Nagata K., Koike J., Todoroki N., Irimura T.: Induction of superoxide anion production from monocytes an neutrophils by activated platelets through the P-selectin-sialyl Lewis X interaction. J. Leukoc. Biol., 1994; 56: 583-587
132. Underhill D.M.: Toll-like receptors: networking for success. Eur. J. Immunol., 2003; 33: 1767-1675
133. Vickers J., Russwurm S., Dohrn B., Portele T., Spangenberg P., Reinhart K., Losche W.: Monocyte tissue factor (CD142) and Mac-1 (CD11b) are increased in septic patients. Thromb. Haemost., 1998; 79: 1219-1220
134. Vidal C., Spaulding C., Picard F., Schaison F., Melle J., Weber S., Fontenay-Roupie M.: Flow cytometry detection of platelet procoagulation activity and microparticles in patients with unstable angina treated by percutaneous coronary angioplasty and stent implantation. Thromb. Haemost., 2001; 86: 784-790
135. Visintin A., Mazzoni A., Spitzer J.H., Wyllie D.H., Dower S.K., Segal D.M.: Regulation of Toll-like receptors in human monocytes and dendritic cells. J. Immunol., 2001; 166: 249-255
136. Wakefield A.J., Sawyerr A.M., Dhillon A.P., Pittilo R.M., Rowles P.M., Lewis A.A., Pounder R.E.: Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction. Lancet, 1989; 2: 1057-1062
137. Werner N., Wassmann S., Ahlers P., Kosiol S., Nickenig G.: Circulating CD31+/annexin V+ apoptotic microparticles correlate with coronary endothelial function in patients with coronary artery disease. Arterioscler. Thromb. Vasc. Biol.,2006; 26: 112-116
138. Weyrich A.S., Elstad M.R., McEver R.P., McIntyre T.M., Moore K.L., Morrissey J.H., Prescott S.M., Zimmerman G.A.: Activated platelets signal chemokine synthesis by human monocytes. J. Clin. Invest., 1996; 97: 1525-1534
139. Williams J.R., Leaver H.A., Ironside J.W., Miller E.P., Whittle I.R., Gregor A.: Apoptosis in human primary brain tumours: actions of arachidonic acid. Prostaglandins Leukot. Essent. Fatty Acids, 1998; 58: 193-200
140. Wright S.D., Ramos RA., Tobias P.S., Ulevitch R.J., Mathison J.C.: CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science, 1990; 249: 1431-1433
141. Wu D., Huang C.K., Jiang H.: Roles of phospholipid signaling in chemoattractant-induced responses. J. Cell. Sci., 2000; 113: 2935-2940
142. Zhang D., Zhang G., Hayden M.S., Greenblatt M.B., Bussey C., Flavell R.A., Ghosh S.: A toll-like receptor that prevents infection by uropathogenic bacteria. Science, 2004; 303: 1522-1526
143. Zhang Y., Chirmule N., Gao G.P., Qian R., Croyle M., Joshi B., Tazelaar J., Wilson J.M.: Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. Mol. Ther., 2001; 3: 697-707
144. Zhao L., Bath P.M., Fox S., May J., Judge H., Losche W., Heptinstall S.: The effects of GPIIb-IIIa antagonists and a combination of three other antiplatelet agents on platelet-leukocyte interactions. Curr. Med. Res. Opin., 2003; 19: 178-186
145. Zhao L., Bath P.M., May J., Losche W., Heptinstall S.: P-selectin, tissue factor and CD40 ligand expression on platelet-leucocyte conjugates in the presence of a GPIIb/IIIa antagonist. Platelets, 2003; 14: 473-480
146. Zillmann A., Luther T., Muller I., Kotzsch M., Spannagl M., Kauke T., Oelschlagel U., Zahler S., Engelmann B.: Platelet-associated tissue factor contributes to the collagen-triggered activation of blood coagulation. Biochem. Biophys. Res. Commun., 2001; 281: 603-609
147. Zucker S., Pei D., Cao J., Lopez-Otin C.: Membrane type-matrix metalloproteinases (MT-MMP). Curr. Top. Dev. Biol., 2003; 54: 1-74