Arachidonic acid as a bioactive molecule

Journal of Clinical Investigation

Volumn 107, Issue 11, 2001, Pages 1339-1345

  Brash, A R ^a  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; ALBUMIN; ARACHIDONIC ACID; BINDING PROTEIN; CANNABINOID RECEPTOR; CARRIER PROTEIN; CYTOCHROME P450; G PROTEIN COUPLED RECEPTOR; LINOLEIC ACID; LIPOXYGENASE; OLEIC ACID; OXYGEN; OXYGENASE; PROSTAGLANDIN SYNTHASE; PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; REVIEW;

EID: 0034983085     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI13210     Document Type: Review

References (46)

1. Effect of solvent polarity on the activity of soybean lipoxygenase isozymes
2. Nature of rate-limiting steps in the soybean lipoxygenase-1 reaction
3. Structure and lipid binding properties of serum albumin
4. Cellular uptake and intracellular trafficking of long chain fatty acids
5. Mechanisms of cellular uptake of long chain free fatty acids
6. Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm
7. Fatty acid transport: Difficult or easy?
8. Thermodynamics of fatty acid transfer
9. Lipid phase fatty acid flip-flop, is it fast enough for cellular transport?
10. Long-chain fatty acid transport in bacteria and yeast. Paradigms for defining the mechanism underlying this protein-mediated process
11. Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4)
12. Membrane glycoprotein CD36: A review of its roles in adherence, signal transduction, and transfusion medicine
13. 3T3 fibroblasts transfected with a cDNA for mitochondrial aspartate aminotransferase express plasma membrane fatty acid-binding protein and saturable fatty acid uptake
14. 18O buffers
15. Preferential utilization of endogenous arachidonate by cyclo-oxygenase in incubations of human platelets
16. Cell biology of the 5-lipoxygenase pathway
17. Characteristics of the formation of the platelet lipoxygenase product from endogenous arachidonic acid
18. Preparation of labeled molecules by exchange with oxygen-18 water
19. Testing models of fatty acid transfer and lipid synthesis in spinach leaf using in vivo oxygen-18 labeling
20. Arachidonate release and phosphatidic acid turnover in stimulated human platelets
21. 2α in epidermis of psoriasis
22. Control of arachidonate levels within inflammatory cells
23. Arachidonic acid induces an increase in the cytosolic calcium concentration in single pancreatic islet beta cells
24. Essentiality of fatty acids
25. Unorthodox routes to prostanoid formation: New twists in cyclooxygenase-initiated pathways
26. Peroxisome proliferator-activated receptors: Three isotypes for a multitude of functions
27. Ligand selectivity of the peroxisome proliferator-activated receptor alpha
28. NADPH oxidase: An update
29. cis-Polyunsaturated fatty acids induce high levels of superoxide production by human neutrophils
30. Essential requirement of cytosolic phospholipase A2 for activation of the phagocyte NADPH oxidase
31. The arachidonate-activatable, NADPH oxidase-associated H+ channel is contained within the multi-membrane-spanning N-terminal region of gp91-phox
32. Evidence that the product of the human X-linked CGD gene, gp91-phox, is a voltage-gated H(+) pathway
33. 2 for activation of the H(+) channel in phagocyte-like cells
34. Arachidonic acid and phosphorylation synergistically induce a conformational change of p47phox to activate the phagocyte NADPH oxidase
35. Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K(+) channel
36. Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty, acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors
37. I(ARC), a novel arachidonate-regulated, noncapacitative Ca(2+) entry channel
38. Arachidonic acid blocks gap junctions between retinal horizontal cells
39. Arachidonic acid stimulates a novel cocaine-sensitive cation conductance associated with the human dopamine transporter
40. Cytoplasmic unsaturated free fatty acids inhibit ATP-dependent gating of the G protein-gated K(+) channel
41. Effect of n-3 and n-6 fatty acids on proliferation and differentiation of promyelocytic leukemic HL-60 cells
42. Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis
43. Identification of arachidonic acid as a mediator of sphingomyelin hydrolysis in response to tumor necrosis factor alpha
44. Relationship between arachidonate-phospholipid remodeling and apoptosis
45. Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells
46. Intracellular unesterified arachidonic acid signals apoptosis