Structure/function relationships of CCR8 agonists and antagonists: Amino-terminal extension of CCL1 by a single amino acid generates a partial agonist

Journal of Biological Chemistry

Volumn 281, Issue 48, 2006, Pages 36652-36661

  Fox, James M ^a   Najarro, Pilar ^b   Smith, Geoffrey L ^b   Struyf, Sofie ^c   Proost, Paul ^c   Pease, James E ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGONISTS; IMMUNE SYSTEM; VIRAL CHEMOKINE;

BIOASSAY; CELL MEMBRANES; IMMUNOLOGY; PROTEINS;

AMINO ACIDS;

ASPARTIC ACID; BETA ARRESTIN 1; BETA ARRESTIN 2; CARBON TETRACHLORIDE; CHEMOKINE; CHEMOKINE CCL1; CHEMOKINE RECEPTOR CCR8; CHEMOKINE RECEPTOR CCR8 AGONIST; CHEMOKINE RECEPTOR CCR8 ANTAGONIST; GLUTAMINE; SODIUM PROTON EXCHANGE PROTEIN 2; THYMUS AND ACTIVATION REGULATED CHEMOKINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; T LYMPHOCYTE;

ASPARTIC ACID; BINDING SITES; CALCIUM; CHEMOKINES, CC; CHEMOTAXIS; GLUTAMIC ACID; LIGANDS; MACROPHAGE INFLAMMATORY PROTEIN-1; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CHEMOKINE; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33846019263     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M605584200     Document Type: Article

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