CCL1-CCR8 interactions: An axis mediating the recruitment of T cells and langerhans-type dendritic cells to sites of atopic skin inflammation

Journal of Immunology

Volumn 174, Issue 8, 2005, Pages 5082-5091

  Gombert, Michael ^a   Dieu Nosjean, Marie Caroline ^b   Winterberg, Franziska ^a   Bünemann, Erich ^a   Kubitza, Robert C ^a   Da Cunha, Ludivine ^b   Haahtela, Anna ^c   Lehtimäki, Sari ^d,e   Müller, Anja ^a   Rieker, Juliane ^a   Meller, Stephan ^a   Pivarcsi, Andor ^a   Koreck, Andrea ^f   Fridman, Wolf Herman ^b   Zentgraf, Hans Walter ^g   Pavenstädt, Hermann ^h   Amara, Ali ⁱ   Caux, Christophe ^j   Kemeny, Lajos ^f   Alenius, Harri ^d,e   Lauerma, Antti ^d,e   Ruzicka, Thomas ^a   Zlotnik, Albert ^k   Homey, Bernhard ^a   more..

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b INSERM   (France)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e FINNISH INSTITUTE OF OCCUPATIONAL HEALTH   (Finland)

^f UNIVERSITY OF SZEGED   (Hungary)

^g GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^h UNIVERSITY OF FREIBURG   (Germany)

ⁱ INSTITUT PASTEUR   (France)

^j MERCK RESEARCH LABORATORIES   (United States)

^k NEUROCRINE BIOSCIENCES INC   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGEN; CCL1 CHEMOKINE; CHEMOKINE; CHEMOKINE RECEPTOR CCR8; IMMUNOGLOBULIN E; UNCLASSIFIED DRUG;

ARTICLE; ATOPIC DERMATITIS; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS LINKING; DENDRITIC CELL; ENDOTHELIUM CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LANGERHANS CELL; MAST CELL; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PSORIASIS; SKIN; SKIN INFLAMMATION; SKIN LUPUS ERYTHEMATOSUS; T LYMPHOCYTE;

EID: 20144387167     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.8.5082     Document Type: Article

References (28)

1. Leung, D. Y., and T. Bieber. 2003. Atopic dermatitis. Lancet 361:151.
2. Simon, D., L. R. Braathen, and H. U. Simon. 2004. Eosinophils and atopic dermatitis. Allergy 59:561.
3. Novak, N., R. Valenta, B. Bohle, S. Laffer, J. Haberstok, S. Kraft, and T. Bieber. 2004. FcεRI engagement of Langerhans cell-like dendritic cells and inflammatory dendritic epidermal cell-like dendritic cells induces chemotactic signals and different T-cell phenotypes in vitro. J. Allergy Clin. Immunol. 113:949.
4. Zlotnik, A., and O. Yoshie. 2000. Chemokines: a new classification system and their role in immunity. Immunity 12:121.
5. Hanifin, J. M., and G. Rajka. 1980. Diagnostic criteria of atopic dermatitis. Acta Derm. Venereol. Suppl. (Stockh) 92:44.
6. Homey, B., W. Wang, H. Soto, M. E. Buchanan, A. Wiesenborn, D. Catron, A. Muller, T. K. McClanahan, M. C. Dieu-Nosjean, R. Orozco, T. Ruzicka, P. Lehmann, E. Oldham, and A. Zlotnik. 2000. Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). J. Immunol. 164:3465.
7. Homey, B., H. Alenius, A. Muller, H. Soto, E. P. Bowman, W. Yuan, L. McEvoy, A. I. Lauerma, T. Assmann, E. Bunemann, et al 2002. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 8:157.
8. Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 179:1109.
9. Geissmann, F., M. C. Dieu-Nosjean, C. Dezutter, J. Valladeau, S. Kayal, M. Leborgne, N. Brousse, S. Saeland, and J. Divoust. 2002. Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin. J. Exp. Med. 196:417.
10. Garrone, P., E. M. Neidhardt, E. Garcia, L. Galibert, C. van Kooten, and J. Banchereau. 1995. Fas ligation induces apoptosis of CD40-activated human B lymphocytes. J. Exp. Med. 182:1265.
11. Benyon, R. C., M. K. Church, L. S. Clegg, and S. T. Holgate. 1986. Dispersion and characterisation of mast cells from human skin. Int. Arch. Allergy Appl. Immunol. 79:332.
12. Dieu-Nosjean, M. C., C. Massacrier, B. Vanbervliet, W. H. Fridman, and C. Caux. 2001. IL-10 induces CCR6 expression during Langerhans cell development while IL-4 and IFN-γ suppress it. J. Immunol. 167:5594.
13. Dieu-Nosjean, M. C., C. Massacrier, B. Homey, B. Vanbervliet, J. J. Pin, A. Vicari, S. Lebecque, C. Dezutter-Dambuyant, D. Schmitt, A. Zlotnik, and C. Caux. 2000. Macrophage inflammatory protein 3α is expressed at inflamed epithelial surfaces and is the most potent chemokine known in attracting Langerhans cell precursors. J. Exp. Med. 192:705.
14. Homey, B., M. C. Dieu-Nosjean, A. Wiesenborn, C. Massacrier, J. J. Pin, E. Oldham, D. Catron, M. E. Buchanan, A. Muller, R. DeWaal Malefyt, et al. 2000. Up-regulation of macrophage inflammatory protein-3α/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immunol. 164:6621.
15. Vanbervliet, B., N. Bendriss-Vermare, C. Massacrier, B. Homey, O. De Bouteiller, F. Briere, G. Trinchieri, and C. Caux. 2003. The Inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12. J. Exp. Med. 198:823.
16. Luther, S. A., A. Bidgol, D. C. Hargreaves, A. Schmidt, Y. Xu, J. Paniyadi, M. Matloubian, and J. G. Cyster. 2002. Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J. Immunol. 169:424.
17. Homey, B., and E. Bunemann. 2004. Chemokirtes and inflammatory skin diseases. Ernst Schering Res. Found Workshop 45:69.
18. Naruse, K., M. Ueno, T. Satoh, H. Nomiyama, H. Tei, M. Takeda, D. H. Ledbetter, E. V. Coillie, G. Opdenakker, N. Gunge, et al. 1996. A YAC contig of the human CC chemokine genes clustered on chromosome 17q11.2. Genomics 34:236.
19. Luttichau, H. R., J. Stine, T. P. Boesen, A. H. Johnsen, D. Chantry, J. Gerstoft, and T. W. Schwartz. 2000. A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus Molluscum contagiosum. J. Exp. Med. 191:171.
20. Wollenberg, A., S. Wetzel, W. H. Burgdorf, and J. Haas. 2003. Viral infections in atopic dermatitis: pathogenic aspects and clinical management. J. Allergy Clin. Immunol. 112:667.
21. Kakinuma, T., K. Nakamura, M. Wakugawa, H. Mitsui, Y. Tada, H. Saeki, H. Torii, A. Asahina, N. Onai, K. Matsushima, and K. Tamaki. 2001. Thymus and activation-regulated chemokine in atopic dermatitis: serum thymus and activation-regulated chemokine level is closely related with disease activity. J. Allergy Clin. Immunol. 107:535.
22. Reiss, Y., A. E. Proudfoot, C. A. Power, J. J. Campbell, and E. C. Butcher. 2001. CC chemokine receptor (CCR)4 and the CCR10 ligand cutaneous T cell-attracting chemokine (CTACK) in lymphocyte trafficking to inflamed skin. J. Exp. Med. 194:1541.
23. Soler, D., T. L. Humphreys, S. M. Spinola, and J. J. Campbell. 2003. CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. Blood 101:1677.
24. Vestergaard, C., M. Deleuran, B. Cesser, and C. Gronhoj Larsen. 2003. Expression of the T-helper 2-specific chemokine receptor CCR4 on CCR10-positive lymphocytes in atopic dermatitis skin but not in psoriasis skin. Br. J. Dermatol. 149:457.
25. Zingoni, A., H. Soto, J. A. Hedrick, A. Stoppacciaro, C. T. Storlazzi, F. Sinigaglia, D. D'Ambrosio, A. O'Garra, D. Robinson, M. Rocchi, et al. 1998. The chemokine receptor CCR8 is preferentially expressed in Th2 but not Th1 cells. J. Immunol. 161:547.
26. Schaerli, P., L. Ebert, K. Willimann, A. Blaser, R. S. Roos, P. Loetscher, and B. Moser. 2004. A skin-selective homing mechanism for human immune surveillance T cells. J. Exp. Med. 199:1265.
27. Mahad, D., C. Trebst, S. M. Staugaitis, P. Kivisakk, B. Tucky, T. Wei, R. Horuk, and R. M. Ransohoff. 2004. Preliminary observations on CC chemokine receptor expression by mononuclear phagocytes in multiple sclerosis lesions: effect of lesion heterogeneity. Ernst Schering Res. Found Workshop 45:59.
28. Ruckes, T., D. Saul, J. Van Snick, O. Hermine, and R. Grassmann. 2001. Autocrine antiapoptotic stimulation of cultured adult T-cell leukemia cells by overexpression of the chemokine 1-309. Blood 98:1150.