The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle

Journal of Biological Chemistry

Volumn 278, Issue 7, 2003, Pages 5179-5187

  Blanpain, Cédric ^a   Doranz, Benjamin J ^b   Bondue, Antoine ^a   Govaerts, Cédric ^a   De Leener, Anne ^a   Vassart, Gilbert ^a   Doms, Robert W ^b   Proudfoot, Amanda ^c   Parmentier, Marc ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c SERONO PHARMACEUTICAL RES INSTITUTE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; VIRUSES;

CHEMOKINES;

PROTEINS;

CHEMOKINE; CHEMOKINE RECEPTOR CCR5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MEMBRANE PROTEIN; RANTES; TRANSMEMBRANE HELIX BUNDLE; UNCLASSIFIED DRUG; MACROPHAGE INFLAMMATORY PROTEIN 1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHIMERA; CONTROLLED STUDY; HUMAN IMMUNODEFICIENCY VIRUS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL MEMBRANE; CHEMISTRY; CHO CELL; GENETICS; HAMSTER; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CHO CELLS; CRICETINAE; HUMANS; MACROPHAGE INFLAMMATORY PROTEIN-1; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RANTES; RECEPTORS, CCR5; SIGNAL TRANSDUCTION;

EID: 0037799237     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205684200     Document Type: Article

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