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Volumn 178, Issue 1, 2007, Pages 111-121

Spleen tyrosine kinase (Syk), a novel target of curcumin, is required for B lymphoma growth

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; PROTEIN BAD; PROTEIN BCL XL; PROTEIN KINASE B; PROTEIN KINASE SYK; TURMERIC;

EID: 33845927271     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.1.111     Document Type: Article
Times cited : (71)

References (68)
  • 3
    • 0032124324 scopus 로고    scopus 로고
    • Curcumin blocks cyclosporine A-resistant CD28 co-stimulatory pathway of human T cell proliferation
    • Ranjan, D., T. D. Johnston, G. Wu, L. Elliott, S. Bondada, and M. Nagabhuskhan. 1998. Curcumin blocks cyclosporine A-resistant CD28 co-stimulatory pathway of human T cell proliferation. J. Surg. Res. 77: 174-178.
    • (1998) J. Surg. Res , vol.77 , pp. 174-178
    • Ranjan, D.1    Johnston, T.D.2    Wu, G.3    Elliott, L.4    Bondada, S.5    Nagabhuskhan, M.6
  • 4
    • 0029757364 scopus 로고    scopus 로고
    • Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines
    • Jiang, M. C., H. F. Yang-Yen, J. J. Yen, and J. K. Lin. 1996. Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines. Nutr. Cancer 26: 111-120.
    • (1996) Nutr. Cancer , vol.26 , pp. 111-120
    • Jiang, M.C.1    Yang-Yen, H.F.2    Yen, J.J.3    Lin, J.K.4
  • 5
    • 0029918159 scopus 로고    scopus 로고
    • Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and DMBA-DNA adduct formation by curcumin
    • Singletary, K., C. MacDonald, M. Wallig, and C. Fisher. 1996. Inhibition of 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary tumorigenesis and DMBA-DNA adduct formation by curcumin. Cancer Lett. 103: 137-141.
    • (1996) Cancer Lett , vol.103 , pp. 137-141
    • Singletary, K.1    MacDonald, C.2    Wallig, M.3    Fisher, C.4
  • 6
    • 23744510724 scopus 로고    scopus 로고
    • Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia
    • Osawa, T., and Y. Kato. 2005. Protective role of antioxidative food factors in oxidative stress caused by hyperglycemia. Ann. NY Acad. Sci. 1043: 440-451.
    • (2005) Ann. NY Acad. Sci , vol.1043 , pp. 440-451
    • Osawa, T.1    Kato, Y.2
  • 8
    • 0028073507 scopus 로고
    • Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice
    • Huang, M. T., Y. R. Lou, W. Ma, H. L. Newmark, K. R. Reuhl, and A. H. Conney. 1994. Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. Cancer Res. 54: 5841-5847.
    • (1994) Cancer Res , vol.54 , pp. 5841-5847
    • Huang, M.T.1    Lou, Y.R.2    Ma, W.3    Newmark, H.L.4    Reuhl, K.R.5    Conney, A.H.6
  • 9
    • 0042168966 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-κB activation through inhibition of IκBα kinase in human lung epithelial cells: Correlation with suppression of COX-2, MMP-9 and cyclin D1
    • Shishodia, S., P. Potdar, C. G. Gairola, and B. B. Aggarwal. 2003. Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-κB activation through inhibition of IκBα kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1. Carcinogenesis 24: 1269-1279.
    • (2003) Carcinogenesis , vol.24 , pp. 1269-1279
    • Shishodia, S.1    Potdar, P.2    Gairola, C.G.3    Aggarwal, B.B.4
  • 10
    • 1842579486 scopus 로고    scopus 로고
    • Nuclear factor-κB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis
    • Bharti, A. C., S. Shishodia, J. M. Reuben, D. Weber, R. Alexanian, S. Raj-Vadhan, Z. Estrov, M. Talpaz, and B. B. Aggarwal. 2004. Nuclear factor-κB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis. Blood 103: 3175-3184.
    • (2004) Blood , vol.103 , pp. 3175-3184
    • Bharti, A.C.1    Shishodia, S.2    Reuben, J.M.3    Weber, D.4    Alexanian, R.5    Raj-Vadhan, S.6    Estrov, Z.7    Talpaz, M.8    Aggarwal, B.B.9
  • 11
    • 0141955061 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells
    • Bharti, A. C., N. Donato, and B. B. Aggarwal. 2003. Curcumin (diferuloylmethane) inhibits constitutive and IL-6-inducible STAT3 phosphorylation in human multiple myeloma cells. J. Immunol. 171: 3863-3871.
    • (2003) J. Immunol , vol.171 , pp. 3863-3871
    • Bharti, A.C.1    Donato, N.2    Aggarwal, B.B.3
  • 13
    • 0032719741 scopus 로고    scopus 로고
    • Enhanced apoptosis mediates inhibition of EBV-transformed lymphoblastoid cell line proliferation by curcumin
    • Ranjan, D., T. D. Johnston, K. S. Reddy, G. Wu, S. Bondada, and C. Chen. 1999. Enhanced apoptosis mediates inhibition of EBV-transformed lymphoblastoid cell line proliferation by curcumin. J. Surg. Res. 87: 1-5.
    • (1999) J. Surg. Res , vol.87 , pp. 1-5
    • Ranjan, D.1    Johnston, T.D.2    Reddy, K.S.3    Wu, G.4    Bondada, S.5    Chen, C.6
  • 14
    • 0037902047 scopus 로고    scopus 로고
    • 4-Hydroxy-3-methoxybenzoic acid methyl ester: A curcumin derivative targets Akt/NF κB cell survival signaling pathway: potential for prostate cancer management
    • Kumar, A. P., G. E. Garcia, R. Ghosh, R. V. Rajnarayanan, W. L. Alworth, and T. J. Slaga. 2003. 4-Hydroxy-3-methoxybenzoic acid methyl ester: a curcumin derivative targets Akt/NF κB cell survival signaling pathway: potential for prostate cancer management. Neoplasia 5: 255-266.
    • (2003) Neoplasia , vol.5 , pp. 255-266
    • Kumar, A.P.1    Garcia, G.E.2    Ghosh, R.3    Rajnarayanan, R.V.4    Alworth, W.L.5    Slaga, T.J.6
  • 15
    • 13844273087 scopus 로고    scopus 로고
    • PI3K-Akt pathway: Its functions and alterations in human cancer
    • Osaki, M., M. Oshimura, and H. Ito. 2004. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 9: 667-676.
    • (2004) Apoptosis , vol.9 , pp. 667-676
    • Osaki, M.1    Oshimura, M.2    Ito, H.3
  • 17
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta, S. R., H. Dudek, X. Tao, S. Masters, H. Fu, Y. Gotoh, and M. E. Greenberg. 1997. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91: 231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 18
    • 0024602619 scopus 로고
    • Isolation and characterization of a B lymphocyte mutant with altered signal transduction through its antigen receptor
    • Monroe, J. G., V. L. Seyfert, C. S. Owen, and N. Sykes. 1989. Isolation and characterization of a B lymphocyte mutant with altered signal transduction through its antigen receptor. J. Exp. Med. 169: 1059.
    • (1989) J. Exp. Med , vol.169 , pp. 1059
    • Monroe, J.G.1    Seyfert, V.L.2    Owen, C.S.3    Sykes, N.4
  • 19
    • 0031415171 scopus 로고    scopus 로고
    • Activation of syk in an immature B cell line does not require lyn activity
    • Muthukkumar, S., C. Venkataraman, T. Woods, and S. Bondada. 1997. Activation of syk in an immature B cell line does not require lyn activity. Mol. Immunol. 34: 865-875.
    • (1997) Mol. Immunol , vol.34 , pp. 865-875
    • Muthukkumar, S.1    Venkataraman, C.2    Woods, T.3    Bondada, S.4
  • 22
    • 0033566911 scopus 로고    scopus 로고
    • The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase
    • Gold, M. R., M. P. Scheid, L. Santos, M. Dang-Lawson, R. A. Roth, L. Matsuuchi, V. Duronio, and D. L. Krebs. 1999. The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase. J. Immunol. 163: 1894-1905.
    • (1999) J. Immunol , vol.163 , pp. 1894-1905
    • Gold, M.R.1    Scheid, M.P.2    Santos, L.3    Dang-Lawson, M.4    Roth, R.A.5    Matsuuchi, L.6    Duronio, V.7    Krebs, D.L.8
  • 23
    • 0035891055 scopus 로고    scopus 로고
    • Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines
    • Mukhopadhyay, A., C. Bueso-Ramos, D. Chatterjee, P. Pantazis, and B. B. Aggarwal. 2001. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene 20: 7597-7609.
    • (2001) Oncogene , vol.20 , pp. 7597-7609
    • Mukhopadhyay, A.1    Bueso-Ramos, C.2    Chatterjee, D.3    Pantazis, P.4    Aggarwal, B.B.5
  • 24
    • 15044361086 scopus 로고    scopus 로고
    • Suppression of the nuclear factor-κB activation pathway by spice-derived phytochemicals: Reasoning for seasoning
    • Aggarwal, B. B., and S. Shishodia. 2004. Suppression of the nuclear factor-κB activation pathway by spice-derived phytochemicals: reasoning for seasoning. Ann. NY Acad. Sci. 1030: 434-441.
    • (2004) Ann. NY Acad. Sci , vol.1030 , pp. 434-441
    • Aggarwal, B.B.1    Shishodia, S.2
  • 26
    • 23744437996 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells
    • Gururajan, M., R. Chui, A. K. Karuppannan, J. Ke, C. D. Jennings, and S. Bondada. 2005. c-Jun N-terminal kinase (JNK) is required for survival and proliferation of B-lymphoma cells. Blood 106: 1382-1391.
    • (2005) Blood , vol.106 , pp. 1382-1391
    • Gururajan, M.1    Chui, R.2    Karuppannan, A.K.3    Ke, J.4    Jennings, C.D.5    Bondada, S.6
  • 27
    • 23444451602 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides stimulate cord blood mononuclear cells to produce immunoglobulins
    • Landers, C. D., and S. Bondada. 2005. CpG oligodeoxynucleotides stimulate cord blood mononuclear cells to produce immunoglobulins. Clin. Immunol. 116: 236-245.
    • (2005) Clin. Immunol , vol.116 , pp. 236-245
    • Landers, C.D.1    Bondada, S.2
  • 28
    • 0018861412 scopus 로고
    • Isolation of human T and B lymphocytes by E-rosette gradient centrifugation: Characterization of the isolated subpopulations
    • Madsen, M., H. E. Johnson, P. W. Hansen, and S. E. Christiansen. 1980. Isolation of human T and B lymphocytes by E-rosette gradient centrifugation: characterization of the isolated subpopulations. J. Immunol. Methods 33: 323-336.
    • (1980) J. Immunol. Methods , vol.33 , pp. 323-336
    • Madsen, M.1    Johnson, H.E.2    Hansen, P.W.3    Christiansen, S.E.4
  • 29
    • 1642499403 scopus 로고    scopus 로고
    • Suppression of PTEN expression by NF-κB prevents apoptosis
    • Vasudevan, K. M., S. Gurumurthy, and V. M. Rangnekar. 2004. Suppression of PTEN expression by NF-κB prevents apoptosis. Mol. Cell. Biol. 24: 1007-1021.
    • (2004) Mol. Cell. Biol , vol.24 , pp. 1007-1021
    • Vasudevan, K.M.1    Gurumurthy, S.2    Rangnekar, V.M.3
  • 30
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen, G. S., and V. M. Dixit. 1997. Caspases: intracellular signaling by proteolysis. Cell 91: 443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 31
    • 0029084999 scopus 로고
    • Modulation of anti-IgM-induced B cell apoptosis by bcl-xL and CD40: Dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction
    • Merino, R., D. A. M. Grillot, P. L. Simonian, S. Muthukkumar, W. C. Fanslow, S. Bondada, and G. Nunez. 1995. Modulation of anti-IgM-induced B cell apoptosis by bcl-xL and CD40: dissociation from cell cycle arrest and dependence on the avidity of the antibody-IgM receptor interaction. J. Immunol. 155: 3830-3838.
    • (1995) J. Immunol , vol.155 , pp. 3830-3838
    • Merino, R.1    Grillot, D.A.M.2    Simonian, P.L.3    Muthukkumar, S.4    Fanslow, W.C.5    Bondada, S.6    Nunez, G.7
  • 32
    • 0035827623 scopus 로고    scopus 로고
    • The adaptor protein BLNK is required for B cell antigen receptor-induced activation of nuclear factor-κB and cell cycle entry and survival of B lymphocytes
    • Tan, J. E.-L., S.-C. Wong, S. K.-E. Gan, S. Xu, and K.-P. Lam. 2001. The adaptor protein BLNK is required for B cell antigen receptor-induced activation of nuclear factor-κB and cell cycle entry and survival of B lymphocytes. J. Biol. Chem. 276: 20055-20063.
    • (2001) J. Biol. Chem , vol.276 , pp. 20055-20063
    • Tan, J.E.-L.1    Wong, S.-C.2    Gan, S.K.-E.3    Xu, S.4    Lam, K.-P.5
  • 33
    • 24044470630 scopus 로고    scopus 로고
    • Expression of constitutively active Akt/protein kinase B signals GLUT4 translocation in the absence of an intact actin cytoskeleton
    • Eyster, C. A., Q. S. Duggins, and A. L. Olson. 2005. Expression of constitutively active Akt/protein kinase B signals GLUT4 translocation in the absence of an intact actin cytoskeleton. J. Biol. Chem. 280: 17978-17985.
    • (2005) J. Biol. Chem , vol.280 , pp. 17978-17985
    • Eyster, C.A.1    Duggins, Q.S.2    Olson, A.L.3
  • 35
    • 1842581764 scopus 로고    scopus 로고
    • Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-κB proteins
    • Patra, A. K., S. Y. Na, and U. Bommhardt. 2004. Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-κB proteins. J. Immunol. 172: 4812-4820.
    • (2004) J. Immunol , vol.172 , pp. 4812-4820
    • Patra, A.K.1    Na, S.Y.2    Bommhardt, U.3
  • 36
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the Rictor-mTOR complex
    • Sarbassov, D. D., D. A. Guertin, S. M. Ali, and D. M. Sabatini. 2005. Phosphorylation and regulation of Akt/PKB by the Rictor-mTOR complex. Science 307: 1098-1101.
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 37
    • 0034613169 scopus 로고    scopus 로고
    • Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress
    • Ding, J., T. Takano, S. Gao, W. Han, C. Noda, S. Yanagi, and H. Yamamura. 2000. Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress. J. Biol. Chem. 275: 30873-30877.
    • (2000) J. Biol. Chem , vol.275 , pp. 30873-30877
    • Ding, J.1    Takano, T.2    Gao, S.3    Han, W.4    Noda, C.5    Yanagi, S.6    Yamamura, H.7
  • 38
    • 0032748581 scopus 로고    scopus 로고
    • Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt
    • Craxton, A., A. Jiang, T. Kurosaki, and E. A. Clark. 1999. Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt. J. Biol. Chem. 274: 30644-30650.
    • (1999) J. Biol. Chem , vol.274 , pp. 30644-30650
    • Craxton, A.1    Jiang, A.2    Kurosaki, T.3    Clark, E.A.4
  • 39
    • 0037018096 scopus 로고    scopus 로고
    • Essential immunoregulatory role for BCAP in B cell development and function
    • Yamazaki, T., K. Takeda, K. Gotoh, H. Takeshima, S. Akira, and T. Kurosaki. 2002. Essential immunoregulatory role for BCAP in B cell development and function. J. Exp. Med. 195: 535-545.
    • (2002) J. Exp. Med , vol.195 , pp. 535-545
    • Yamazaki, T.1    Takeda, K.2    Gotoh, K.3    Takeshima, H.4    Akira, S.5    Kurosaki, T.6
  • 40
    • 0034663163 scopus 로고    scopus 로고
    • SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization
    • Carver, D. J., M. J. Aman, and K. S. Ravichandran. 2000. SHIP inhibits Akt activation in B cells through regulation of Akt membrane localization. Blood 96: 1449-1456.
    • (2000) Blood , vol.96 , pp. 1449-1456
    • Carver, D.J.1    Aman, M.J.2    Ravichandran, K.S.3
  • 41
    • 0025873239 scopus 로고
    • B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase
    • Hutchcroft, J. E., M. L. Harrsion, and R. L. Geahlen. 1991. B lymphocyte activation is accompanied by phosphorylation of a 72-kDa protein-tyrosine kinase. J. Biol. Chem. 266: 14846-14849.
    • (1991) J. Biol. Chem , vol.266 , pp. 14846-14849
    • Hutchcroft, J.E.1    Harrsion, M.L.2    Geahlen, R.L.3
  • 42
    • 0032719863 scopus 로고    scopus 로고
    • Preclinical and phase I and II trials of rituximab
    • Maloney, D. G. 1999. Preclinical and phase I and II trials of rituximab. Semin. Oncol. 26: 74-78.
    • (1999) Semin. Oncol , vol.26 , pp. 74-78
    • Maloney, D.G.1
  • 45
    • 1342321750 scopus 로고    scopus 로고
    • PI 3-kinase, Akt and cell survival
    • Downward, J. 2004. PI 3-kinase, Akt and cell survival. Semin. Cell Dev. Biol. 15: 177-182.
    • (2004) Semin. Cell Dev. Biol , vol.15 , pp. 177-182
    • Downward, J.1
  • 46
    • 0033517190 scopus 로고    scopus 로고
    • NF-κB is a target of AKT in anti-apoptotic PDGF signalling
    • Romashkova, J. A., and S. S. Makarov. 1999. NF-κB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401: 86-90.
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 47
    • 0033517189 scopus 로고    scopus 로고
    • NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes, O. N., L. D. Mayo, J. A. Gustin, S. R. Pfeffer, L. M. Pfeffer, and D. B. Donner. 1999. NF-κB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401: 82-85.
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 48
    • 30044446136 scopus 로고    scopus 로고
    • Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation
    • Aggarwal, S., H. Ichikawa, Y. Takada, S. K. Sandur, S. Shishodia, and B. B. Aggarwal. 2006. Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of IκBα kinase and Akt activation. Mol. Pharmacol. 69: 195-206.
    • (2006) Mol. Pharmacol , vol.69 , pp. 195-206
    • Aggarwal, S.1    Ichikawa, H.2    Takada, Y.3    Sandur, S.K.4    Shishodia, S.5    Aggarwal, B.B.6
  • 50
    • 0031456145 scopus 로고    scopus 로고
    • Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool
    • Turner, M., A. Gulbranson-Judge, M. E. Quinn, A. E. Walters, I. C. MacLennan, and V. L. Tybulewicz. 1997. Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool. J. Exp. Med. 186: 2013-2021.
    • (1997) J. Exp. Med , vol.186 , pp. 2013-2021
    • Turner, M.1    Gulbranson-Judge, A.2    Quinn, M.E.3    Walters, A.E.4    MacLennan, I.C.5    Tybulewicz, V.L.6
  • 52
    • 12544249891 scopus 로고    scopus 로고
    • Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase
    • Moon, K. D., C. B. Post, D. L. Durden, Q. Zhou, P. De, M. L. Harrison, and R. L. Geahlen. 2005. Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase. J. Biol. Chem. 280: 1543-1551.
    • (2005) J. Biol. Chem , vol.280 , pp. 1543-1551
    • Moon, K.D.1    Post, C.B.2    Durden, D.L.3    Zhou, Q.4    De, P.5    Harrison, M.L.6    Geahlen, R.L.7
  • 53
    • 0037199989 scopus 로고    scopus 로고
    • Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines: A mechanism for negative signaling by the Lyn tyrosine kinase
    • Hong, J. J., T. M. Yankee, M. L. Harrison, and R. L. Geahlen. 2002. Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines: a mechanism for negative signaling by the Lyn tyrosine kinase. J. Biol. Chem. 277: 31703-31714.
    • (2002) J. Biol. Chem , vol.277 , pp. 31703-31714
    • Hong, J.J.1    Yankee, T.M.2    Harrison, M.L.3    Geahlen, R.L.4
  • 54
    • 0029589233 scopus 로고    scopus 로고
    • Singh, S., and B. B. Aggarwal. 1995. Activation of transcription factor NF-κB is suppressed by curcumin (diferuloylmethane). [Published erratum appears in 1995 J. Biol. Chem. 270: 30235.]
    • Singh, S., and B. B. Aggarwal. 1995. Activation of transcription factor NF-κB is suppressed by curcumin (diferuloylmethane). [Published erratum appears in 1995 J. Biol. Chem. 270: 30235.]
  • 55
    • 85039136500 scopus 로고    scopus 로고
    • J. Biol. Chem
    • J. Biol. Chem. 270: 24995-25000.
    • , vol.270 , pp. 24995-25000
  • 56
    • 0036019942 scopus 로고    scopus 로고
    • Role of protein-tyrosine kinase syk in oxidative stress signaling in B cells
    • Takano, T., K. Sada, and H. Yamamura. 2002. Role of protein-tyrosine kinase syk in oxidative stress signaling in B cells. Antioxid. Redox Signal. 4: 533-541.
    • (2002) Antioxid. Redox Signal , vol.4 , pp. 533-541
    • Takano, T.1    Sada, K.2    Yamamura, H.3
  • 57
    • 0034254421 scopus 로고    scopus 로고
    • B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase
    • Pogue, S. L., T. Kurosaki, J. Bolen, and R. Herbst. 2000. B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase. J. Immunol. 165: 1300-1306.
    • (2000) J. Immunol , vol.165 , pp. 1300-1306
    • Pogue, S.L.1    Kurosaki, T.2    Bolen, J.3    Herbst, R.4
  • 58
    • 3142665469 scopus 로고    scopus 로고
    • TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-κB activation, and apoptosis
    • Takada, Y., and B. B. Aggarwal. 2004. TNF activates Syk protein tyrosine kinase leading to TNF-induced MAPK activation, NF-κB activation, and apoptosis. J. Immunol. 173: 1066-1077.
    • (2004) J. Immunol , vol.173 , pp. 1066-1077
    • Takada, Y.1    Aggarwal, B.B.2
  • 59
    • 1642483742 scopus 로고    scopus 로고
    • 2-terminal kinase activation in human neutrophils: Role of phosphatidylinositol 3-kinase and Syk-mediated pathways
    • 2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-kinase and Syk-mediated pathways. J. Biol. Chem. 279: 10883-10891.
    • (2004) J. Biol. Chem , vol.279 , pp. 10883-10891
    • Arndt, P.G.1    Suzuki, N.2    Avdi, N.J.3    Malcolm, K.C.4    Worthen, G.S.5
  • 60
    • 0345016388 scopus 로고    scopus 로고
    • Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia
    • Kim, H. Y., E. J. Park, E. H. Joe, and I. Jou. 2003. Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J. Immunol. 171: 6072-6079.
    • (2003) J. Immunol , vol.171 , pp. 6072-6079
    • Kim, H.Y.1    Park, E.J.2    Joe, E.H.3    Jou, I.4
  • 61
    • 0344962391 scopus 로고    scopus 로고
    • Direct inhibitory effect of curcumin on Src and focal adhesion kinase activity
    • Leu, T. H., S. L. Su, Y. C. Chuang, and M. C. Maa. 2003. Direct inhibitory effect of curcumin on Src and focal adhesion kinase activity. Biochem. Pharmacol. 66: 2323-2331.
    • (2003) Biochem. Pharmacol , vol.66 , pp. 2323-2331
    • Leu, T.H.1    Su, S.L.2    Chuang, Y.C.3    Maa, M.C.4
  • 62
    • 28544449211 scopus 로고    scopus 로고
    • Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression
    • Wang, L., E. Devarajan, J. He, S. P. Reddy, and J. L. Dai. 2005. Transcription repressor activity of spleen tyrosine kinase mediates breast tumor suppression. Cancer Res. 65: 10289-10297.
    • (2005) Cancer Res , vol.65 , pp. 10289-10297
    • Wang, L.1    Devarajan, E.2    He, J.3    Reddy, S.P.4    Dai, J.L.5
  • 63
    • 18844372227 scopus 로고    scopus 로고
    • Syk tyrosine kinase expression during multistep mammary carcinogenesis
    • Gatalica, Z., and Z. Bing. 2005. Syk tyrosine kinase expression during multistep mammary carcinogenesis. Croat. Med. J. 46: 372-376.
    • (2005) Croat. Med. J , vol.46 , pp. 372-376
    • Gatalica, Z.1    Bing, Z.2
  • 64
    • 0037427571 scopus 로고    scopus 로고
    • Reduced expression of the Syk gene is correlated with poor prognosis in human breast cancer
    • Toyama, T., H. Iwase, H. Yamashita, Y. Hara, Y. Omoto, H. Sugiura, Z. Zhang, and Y. Fujii. 2003. Reduced expression of the Syk gene is correlated with poor prognosis in human breast cancer. Cancer Lett. 189: 97-102.
    • (2003) Cancer Lett , vol.189 , pp. 97-102
    • Toyama, T.1    Iwase, H.2    Yamashita, H.3    Hara, Y.4    Omoto, Y.5    Sugiura, H.6    Zhang, Z.7    Fujii, Y.8
  • 65
    • 0035879017 scopus 로고    scopus 로고
    • Hypermethylation leads to silencing of the SYK gene in human breast cancer
    • Yuan, Y., R. Mendez, A. Sahin, and J. L. Dai. 2001. Hypermethylation leads to silencing of the SYK gene in human breast cancer. Cancer Res. 61: 5558-5561.
    • (2001) Cancer Res , vol.61 , pp. 5558-5561
    • Yuan, Y.1    Mendez, R.2    Sahin, A.3    Dai, J.L.4
  • 66
  • 67
    • 2942582913 scopus 로고    scopus 로고
    • Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer
    • Kraus, M., M. B. Alimzhanov, N. Rajewsky, and K. Rajewsky. 2004. Survival of resting mature B lymphocytes depends on BCR signaling via the Igα/β heterodimer. Cell 117: 787.
    • (2004) Cell , vol.117 , pp. 787
    • Kraus, M.1    Alimzhanov, M.B.2    Rajewsky, N.3    Rajewsky, K.4
  • 68
    • 33646492861 scopus 로고    scopus 로고
    • Cutting edge: Constitutive B cell receptor signaling is critical for basal growth of B lymphoma
    • Gururajan, M., C. D. Jennings, and S. Bondada. 2006. Cutting edge: constitutive B cell receptor signaling is critical for basal growth of B lymphoma. J. Immunol. 176: 5715-5719.
    • (2006) J. Immunol , vol.176 , pp. 5715-5719
    • Gururajan, M.1    Jennings, C.D.2    Bondada, S.3


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