Role of protein-tyrosine kinase Syk in oxidative stress signaling in B cells

Antioxidants and Redox Signaling

Volumn 4, Issue 3, 2002, Pages 533-541

  Takano, Tomoko ^a   Sada, Kiyonao ^a   Yamamura, Hirohei ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; AKT1 PROTEIN, HUMAN; CALCIUM; ENZYME PRECURSOR; LYN PROTEIN-TYROSINE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE LYN; PROTEIN KINASE SYK; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; B LYMPHOCYTE ACTIVATION; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL FATE; CELL FUNCTION; CELL SURVIVAL; ENZYME ACTIVATION; GENE DISRUPTION; MEDIATOR RELEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; B LYMPHOCYTE; CELL CYCLE; HUMAN; METABOLISM; PHYSIOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; B-LYMPHOCYTES; CALCIUM; CELL CYCLE; ENZYME PRECURSORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 0036019942     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/15230860260196335     Document Type: Review

References (79)

1. Epidermal growth factor (EGF)-induced generation of hydrogen peroxide: Role in EGF receptor-mediated tyrosine phosphorylation
2. Functions of lipid rafts in biological membranes
3. Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase
4. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
5. Regulation of cell death protease caspase-9 by phosphorylation
6. Participation of reactive oxygen species in the lysophosphatidic acid-stimulated mitogen-activated protein kinase kinase activation pathway
7. Syk tyrosine kipase required for mouse viability and B-cell development
8. The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells
9. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
10. Distinctive functions of Syk N-terminal and C-terminal SH2 domains in the signaling cascade elicited by oxidative stress in B cells
11. Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress
12. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
13. The generation of oxygen radicals: A positive signal for lymphocyte activation
14. BLNK: A central linker protein in B cell activation
15. Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide
16. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
17. 2: Role in cell survival following oxidant injury
18. Oxygen toxicity, oxygen radicals, transition metals and disease
19. Role of free radicals and catalytic metal ions in human disease: An overview
20. Role of BLNK in oxidative stress signaling in B cells
21. 2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor
22. Syk is required for p38 activation and G2/M arrest in B cells exposed to oxidative stress
23. SAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosis
24. 2-induced activation of SAPK/JNK but not for that of p38 and ERK in Chinese hamster V79 cells
25. 2 and Racl-JNK in B cells
26. 2-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells
27. Induction of NF-κB by the Akt/PKB kinase
28. Activation of protein kinase B (Akt/RAC-protein kinase) by cellular stress and its association with heat shock protein Hsp 27
29. 2 generation in 3T3 L1-cells
30. Characterisation of calcium signalling in DT40 chicken B cells
31. Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress
32. Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
33. p21ras as a common signaling target of reactive free radicals and cellular redox stress
34. Bcl-2 does not protect Burkitt's lymphoma cells from oxidant-induced cell death
35. Oxidative stress inhibits apoptosis in human lymphoma cells
36. Cytochrome c and dATP- dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
37. Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
38. Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes
39. Hydrogen peroxide as a potent activator of T lymphocyte functions
40. i in induction of c-fos, c-jun, and c-myc mRNA in rat PTE after oxidative stress
41. The insulin-like effect of hydrogen peroxide on pathways of lipid synthesis in rat adipocytes
42. Human fibroblasts release reactive oxygen species in response to interleukin-1 or tumour necrosis factor-alpha
43. 2 and antioxidants have opposite effects on activation of NF-κB and AP-1 in intact cells: AP-1 as secondary antioxidant responsive factor
44. Role of Syk protein kinase in stress-induced signaling in B cells
45. Redox regulation of cellular activation
46. Redox-linked signal transduction pathways for protein tyrosine kinase activation
47. Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic cells
48. Effect of in vitro generation of oxygen free radicals on T cell function in young and old rats
49. lyn regulates calcium mobilization in chicken B cell oxidant stress signaling
50. Syk-dependent and -independent signaling cascades in B cells elicited by osmotic and oxidative stress
51. Differential regulation of oxidative and osmotic stress induced Syk activation by both autophosphorylation and SH2 domains
52. Regulation of oxidative stress-induced calcium release by phosphatidylinositol 3-kinase and Bruton's tyrosine kinase in B cells
53. Production of hydrogen peroxide by murine epidermal keratinocytes following treatment with the tumor promoter 12-O-tetradecanoylphorbol-13-acetate
54. Mitogen-activated protein kinase pathways
55. Structure and function of Syk protein-tyrosine kinase
56. fyn tyrosine kinases in human lymphocytes
57. 2+ signals
58. 2-induced T cell signal transduction
59. Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosis
60. 2 for platelet-derived growth factor signal transduction
61. Oxidative stress triggers tyrosine phosphorylation in B cells through a redox- and inflammatory cytokine-sensitive mechanism
62. 2+ mobilization through distinct pathways
63. 2 activation in surface immunoglobulin M-induced B cell apoptosis
64. Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest
65. Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis
66. The role of reactive oxygen species in triggering proliferation and IL-2 secretion in T cells
67. 2-generating NADH oxidase in human lung fibroblasts by transforming growth factor β1
68. Purification of a 72-kDa protein-tyrosine kinase from rat liver and its identification as Syk: Involvement of Syk in signaling events of hepatocytes
69. Syk protein-tyrosine kinase is involved in neuron-like differentiation of embryonal carcinoma P19 cells
70. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk
71. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
72. G(s)alpha repression of adipogenesis via Syk
73. The cellular response to oxidative stress: Influence of mitogen-activated protein kinase signalling pathways on cell survival
74. Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast
75. Oxygen free radical generation and regulation of proliferative activity of human mononuclear cells responding to different mitogens
76. Opposing effects of ERK and JNK-p38 MAP kinase on apoptosis
77. Protein-tyrosine kinase Syk expressed in human nasal fibroblasts and its effect on RANTES production
78. SYK expressed in hematopoietic cells
79. Syk expression in endothelial cells and their morphologic defects in embryonic Syk-deficient mice