The molecular receptive range of an olfactory receptor in vivo (Drosophila melanogaster Or22a)

Journal of Neurobiology

Volumn 66, Issue 14, 2006, Pages 1544-1563

  Pelz, Daniela ^a   Roeske, Tina ^a   Syed, Zainulabeuddin ^a,c   De Bruyne, Marien ^a,d   Galizia, C Giovanni ^a,b  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Calcium imaging; In vivo recording; Molecular response profile; Olfaction; Receptor neurons

Indexed keywords

CALCIUM; G PROTEIN COUPLED RECEPTOR; HEXANOIC ACID; HEXANOIC ACID ETHYL ESTER; INSECT PROTEIN; METHYL HEXANOATE; PROTEIN OR22A; UNCLASSIFIED DRUG;

ANTENNA; ANTENNAL LOBE; ARTICLE; CALCIUM TRANSPORT; CELL STIMULATION; CONCENTRATION RESPONSE; DROSOPHILA MELANOGASTER; EVOKED SOMATOSENSORY RESPONSE; GLOMERULAR STRUCTURE; IN VIVO STUDY; INSECT; MOLECULAR RECEPTIVE RANGE; NERVE CONDUCTION; NEUROBIOLOGY; NONHUMAN; ODOR; OLFACTORY BULB; OLFACTORY NUCLEUS; OLFACTORY RECEPTOR; OLFACTORY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RECEPTOR SENSITIVITY; SENSORY NERVE CELL; SMELLING; VERTEBRATE;

ANIMALS; CALCIUM; DIAGNOSTIC IMAGING; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GREEN FLUORESCENT PROTEINS; MEMBRANE POTENTIALS; ODORS; OLFACTORY PATHWAYS; OLFACTORY RECEPTOR NEURONS; PATCH-CLAMP TECHNIQUES; PROMOTER REGIONS (GENETICS); RECEPTORS, ODORANT; SENSE ORGANS;

EID: 33845787441     PISSN: 00223034     EISSN: 10974695     Source Type: Journal    
DOI: 10.1002/neu.20333     Document Type: Article

References (66)

1. Araneda RC, Kini AD, Firestein S. 2000. The molecular receptive range of an odorant receptor. Nat Neurosci 3:1248-1255.
2. Aroniadou-Anderjaska V, Zhou FM, Priest CA, Ennis M, Shipley MT. 2000. Tonic and synaptically evoked presynaptic inhibition of sensory input to the rat olfactory bulb via GABA(B) heteroreceptors. J Neurophysiol 84:1194-1203.
3. Aubert C, Bourger N. 2004. Investigation of volatiles in Charentais cantaloupe melons (Cucumis melo var cantalupensis). Characterization of aroma constituents in some cultivars. J Agric Food Chem 52:4522-4528.
4. Benton R, Sachse S, Michnick SW, Vosshall LB. 2006. Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol 4:e20.
5. Bhalerao S, Sen A, Stocker R, Rodrigues V. 2003. Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster. J Neurobiol 54:577-592.
6. Bozza T, Feinstein P, Zheng C, Mombaerts P. 2002. Odorant receptor expression defines functional units in the mouse olfactory system. J Neurosci 22:3033-3043.
7. Buck L, Axel R. 1991. A novel multigene family may encode odorant receptors: A molecular basis for odor recognition. Cell 65:175-187.
8. Clyne PJ, Warr CG, Freeman MR, Lessing D, Kim J, Carlson JR. 1999. A novel family of divergent seven-transmembrane proteins: Candidate odorant receptors in Drosophila. Neuron 22:327-338.
9. Cometto-Muniz JE, Cain WS, Abraham MH. 2003. Quantification of chemical vapors in chemosensory research. Chem Senses 28:467-477.
10. Costa T, Cotecchia S. 2005. Historical review: Negative efficacy and the constitutive activity of G-protein-coupled receptors. Trends Pharmacol Sci 26:618-624.
11. Couto A, Alenius M, Dickson BJ. 2005. Molecular, anatomical, and functional organization of the Drosophila olfactory system. Curr Biol 15:1535-1547.
12. de Bruyne M, Clyne PJ, Carlson JR. 1999. Odor coding in a model olfactory organ: The Drosophila maxillary palp. J Neurosci 19:4520-4532.
13. de Bruyne M, Foster K, Carlson JR. 2001. Odor coding in the Drosophila antenna. Neuron 30:537-552.
14. Dobritsa AA, van der Goesvan Naters W, Warr CG, Steinbrecht RA, Carlson JR. 2003. Integrating the molecular and cellular basis of odor coding in the Drosophila antenna. Neuron 37:827-841.
15. Ennis M, Zhou FM, Ciombor KJ, Aroniadou-Anderjaska V, Hayar A, Borrelli E, Zimmer LA, et al. 2001. Dopamine D2 receptor-mediated presynaptic inhibition of olfactory nerve terminals. J Neurophysiol 86:2986-2997.
16. Estes PS, Roos J, van der Bliek A, Kelly RB, Krishnan KS, Ramaswami M. 1996. Traffic of dynamin within individual Drosophila synaptic boutons relative to compartment-specific markers. J Neurosci 16:5443-5456.
17. Fiala A, Spall T, Diegelmann S, Eisermann B, Sachse S, Devaud JM, Buchner E, et al. 2002. Genetically expressed cameleon in Drosophila melanogaster is used to visualize olfactory information in projection neurons. Curr Biol 12:1877-1884.
18. Fishilevich E, Vosshall LB. 2005. Genetic and functional subdivision of the Drosophila antennal lobe. Curr Biol 15:1548-1553.
19. Gao Q, Chess A. 1999. Identification of candidate Drosophila olfactory receptors from genomic DNA sequence. Genomics 60:31-39.
20. Grosmaitre X, Vassalli A, Mombaerts P, Shepherd GM, Ma M. 2006. Odorant responses of olfactory sensory neurons expressing the odorant receptor MOR23: A patch clamp analysis in gene-targeted mice. Proc Natl Acad Sci USA 103:1970-1975.
21. Hallem EA, Carlson JR. 2006. Coding of odors by a receptor repertoire. Cell 125:143-160.
22. Hallem EA, Ho MG, Carlson JR. 2004. The molecular basis of odor coding in the Drosophila antenna. Cell 117:965-979.
23. Hildebrand JG, Shepherd GM. 1997. Mechanisms of olfactory discrimination: Converging evidence for common principles across phyla. Annu Rev Neurosci 20:595-631.
24. Höger U, Torkkeli PH, French AS. 2005. Calcium concentration changes during sensory transduction in spider mechanoreceptor neurons. Eur J Neurosci 22:3171-3178.
25. Jordan MJ, Goodner KL, Shaw PE. 2002. Characterization of the aromatic profile in aqueous essence and fruit juice of yellow passion fruit (Passiflora edulis Sims F. Flavicarpa degner) by GC-MS and GC/O. J Agric Food Chem 50:1523-1528.
26. Jordan MJ, Margaria CA, Shaw PE, Goodner KL. 2003. Volatile components and aroma active compounds in aqueous essence and fresh pink guava fruit puree (Psidium guajava L.) by GC-MS and multidimensional GC/GC-O. J Agric Food Chem 51:1421-1426.
27. Jordan MJ, Shaw PE, Goodner KL. 2001a. Volatile components in aqueous essence and fresh fruit of Cucumis melo cv. Athena (muskmelon) by GC-MS and GC-O. J Agric Food Chem 49:5929-5933.
28. Jordan MJ, Tandon K, Shaw PE, Goodner KL. 2001b. Aromatic profile of aqueous banana essence and banana fruit by gas chromatography-mass spectrometry (GC-MS) and gas chromatography-olfactometry (GC-O). J Agric Food Chem 49:4813-4817.
29. Katada S, Hirokawa T, Oka Y, Suwa M, Touhara K. 2005. Structural basis for a broad but selective ligand spectrum of a mouse olfactory receptor: Mapping the odorant-binding site. J Neurosci 25:1806-1815.
30. Laissue PP, Reiter C, Hiesinger PR, Halter S, Fischbach KF, Stocker RF. 1999. Three-dimensional reconstruction of the antennal lobe in Drosophila melanogaster. J Comp Neurol 405:543-552.
31. Larsson MC, Domingos AI, Jones WD, Chiappe ME, Amrein H, Vosshall LB. 2004. Or83b encodes a broadly expressed odorant receptor essential for Drosophila olfaction. Neuron 43:703-714.
32. Lewcock JW, Reed RR. 2004. A feedback mechanism regulates monoallelic odorant receptor expression. Proc Natl Acad Sci USA 101:1069-1074.
33. Loughrin JH, Kasperbauer MJ. 2002. Aroma of fresh strawberries is enhanced by ripening over red versus black mulch. J Agric Food Chem 50:161-165.
34. Luu P, Acher F, Bertrand HO, Fan J, Ngai J. 2004. Molecular determinants of ligand selectivity in a vertebrate odorant receptor. J Neurosci 24:10128-10137.
35. Malnic B, Hirono J, Sato T, Buck LB. 1999. Combinatorial receptor codes for odors. Cell 96:713-723.
36. Matthews HR, Reisert J. 2003. Calcium, the two-faced messenger of olfactory transduction and adaptation. Curr Opin Neurobiol 13:469-475.
37. Meister M, Bonhoeffer T. 2001. Tuning and topography in an odor map on the rat olfactory bulb. J Neurosci 21:1351-1360.
38. 2+ measurements using improved cameleons. Proc Natl Acad Sci USA 96:2135-2140.
39. Mombaerts P, Wang F, Dulac C, Chao SK, Nemes A, Mendelsohn M, Edmondson J, et al. 1996. Visualizing an olfactory sensory map. Cell 87:675-686.
40. Mori K, Shepherd GM. 1994. Emerging principles of molecular signal processing by mitral/tufted cells in the olfactory bulb. Semin Cell Biol 5:65-74.
41. Motulsky H, Christopoulos A. 2004. Fitting Models to Biological Data Using Linear and Nonlinear Regression. Oxford: Oxford University Press, 351p.
42. Neuhaus EM, Gisselmann G, Zhang W, Dooley R, Stortkuhl K, Hatt H. 2005. Odorant receptor heterodimerization in the olfactory system of Drosophila melanogaster. Nat Neurosci 8:15-17.
43. Pino JA, Mesa J, Munoz Y, Marti MP, Marbot R. 2005. Volatile components from mango (Mangifera indica L.) cultivars. J Agric Food Chem 53:2213-2223.
44. Pophof B. 2004. Pheromone-binding proteins contribute to the activation of olfactory receptor neurons in the silkmoths antheraea polyphemus and Bombyx mori. Chem Senses 29:117-125.
45. Reiff DF, Hiring A, Guerrero G, Isacoff EY, Joesch M, Nakai J, Borst A. 2005. In vivo performance of genetically encoded indicators of neural activity in flies. J Neurosci 25: 4766-4778.
46. 2+ concentration in salamander olfactory receptor cells. J Physiol 535:637-645.
47. Ressler KJ, Sullivan SL, Buck LB. 1994. Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79:1245-1255.
48. Sachse S, Galizia CG. 2003. The coding of odour-intensity in the honeybee antennal lobe: Local computation optimizes odour representation. Eur J Neurosci 18:2119-2132.
49. Serizawa S, Miyamichi K, Nakatani H, Suzuki M, Saito M, Yoshihara Y, Sakano H. 2003. Negative feedback regulation ensures the one receptor-one olfactory neuron rule in mouse. Science 302:2088-2094.
50. Shirokova E, Schmiedeberg K, Bedner P, Niessen H, Willecke K, Raguse JD, Meyerhof W, et al. 2005. Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants. J Biol Chem 280:11807-11815.
51. Spehr M, Gisselmann G, Poplawski A, Riffell JA, Wetzel CH, Zimmer RK, Hatt H. 2003. Identification of a testicular odorant receptor mediating human sperm chemotaxis. Science 299:2054-2058.
52. Stengl M. 1994. Inositol-trisphosphate-dependent calcium currents precede cation currents in insect olfactory receptor neurons in vitro. J Comp Physiol [A] 174:187-194.
53. Stensmyr MC, Giordano E, Balloi A, Angioy AM, Hansson BS. 2003. Novel natural ligands for Drosophila olfactory receptor neurones. J Exp Biol 206:715-724.
54. Stocker RF. 1994. The organization of the chemosensory system in Drosophila melanogaster. A review. Cell Tissue Res 275:3-26.
55. Stocker RF. 2001. Drosophila as a focus in olfactory research: Mapping of olfactory sensilla by fine structure, odor specificity, odorant receptor expression, and central connectivity. Microsc Res Tech 55:284-296.
56. Stocker RF, Lienhard MC, Borst A, Fischbach KF. 1990. Neuronal architecture of the antennal lobe in Drosophila melanogaster. Cell Tissue Res 262:9-34.
57. Takeuchi H, Kurahashi T. 2005. Mechanism of signal amplification in the olfactory sensory cilia. J Neurosci 25:11084-11091.
58. Vassar R, Chao SK, Sitcheran R, Nuñez JM, Vosshall LB, Axel R. 1994. Topographic organization of sensory projections to the olfactory bulb. Cell 79:981-991.
59. Vosshall LB, Amrein H, Morozov PS, Rzhetsky A, Axel R. 1999. A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96:725-736.
60. Vosshall LB, Wong AM, Axel R. 2000. An olfactory sensory map in the fly brain. Cell 102:147-159.
61. Wachowiak M, Cohen LB. 1998. Presynaptic afferent inhibition of lobster olfactory receptor cells: Reduced action-potential propagation into axon terminals. J Neurophysiol 80:1011-1015.
62. Wachowiak M, Cohen LB. 1999. Presynaptic inhibition of primary olfactory afferents mediated by different mechanisms in lobster and turtle. J Neurosci 19:8808-8817.
63. Wachowiak M, Cohen LB. 2001. Representation of odorants by receptor neuron input to the mouse olfactory bulb. Neuron 32:723-735.
64. Wachowiak M, McGann JP, Heyward PM, Shao Z, Puche AC, Shipley MT. 2005. Inhibition of olfactory receptor neuron input to olfactory bulb glomeruli mediated by suppression of presynaptic calcium influx. J Neurophysiol 94:2700-2712.
65. Wilson RI, Turner GC, Laurent G. 2004. Transformation of olfactory representations in the Drosophila antennal lobe. Science 303:366-370.
66. Xu P, Atkinson R, Jones DN, Smith DP. 2005. Drosophila OBP LUSH is required for activity of pheromone-sensitive neurons. Neuron 45:193-200.