Olfactory neurons expressing identified receptor genes project to subsets of glomeruli within the antennal lobe of Drosophila melanogaster

Journal of Neurobiology

Volumn 54, Issue 4, 2003, Pages 577-592

  Bhalerao, Sheetal ^a   Sen, Anindya ^a   Stocker, Reinhard ^b   Rodrigues, Veronica ^a,c  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^b UNIVERSITY OF FRIBOURG   (Switzerland)

^c TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Antennal lobe; Drosophila; Glomeruli; Odorant receptors; Olfactory sense organs

Indexed keywords

GREEN FLUORESCENT PROTEIN;

ANIMAL CELL; ARTICLE; BRAIN; CELL FUNCTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; GLOMERULUS; INNERVATION; NERVE CELL; NONHUMAN; OLFACTORY BULB; OLFACTORY DISCRIMINATION; OLFACTORY SYSTEM; PRIORITY JOURNAL; RECEPTOR GENE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ARTIFICIAL GENE FUSION; BRAIN; DROSOPHILA MELANOGASTER; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MULTIGENE FAMILY; OLFACTORY BULB; OLFACTORY PATHWAYS; OLFACTORY RECEPTOR NEURONS; PROMOTER REGIONS (GENETICS); R-SNARE PROTEINS; RECEPTORS, ODORANT; SENSE ORGANS;

EID: 0037370677     PISSN: 00223034     EISSN: None     Source Type: Journal    
DOI: 10.1002/neu.10175     Document Type: Article

References (41)

1. Belluscio L, Koentges G, Axel R, Dulac C. 1999. A map of pheromone receptor activation in the mammalian brain. Cell 97:209-220.
2. Bozza T, Feinstein P, Zheng C, Mombaerts P. 2002. Odorant receptor expression defines functional units in the mouse olfactory system. J Neurosci 22:3033-3043.
3. Brand AH, Perrimon N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415
4. Buck LB. 1996. Information coding in the vertebrate olfactory system. Ann Rev Neurosci 19:517-544.
5. Clyne PJ, Warr CG, Freeman MR, Lessing D, Kim J, Carlson JR. 1999. A novel family of divergent seven transmembrane proteins: candidate odorant receptors in Drosophila. Neuron 22:327-338.
6. de Bruyne M, Foster K, Carlson JR. 2001. Odor coding in the Drosophila antenna. Neuron 30:537-552.
7. Elmore T, Smith DP. 2001. Putative Drosophila odor receptor OR43b localizes to dendrites of olfactory neurons. Insect Biochem Mol Biol 31:791-798.
8. Galizia CG, Kuttner A, Joerges J, Menzel R. 2000. Odour representation in the honeybee olfactory glomeruli show slow temporal dynamics: an optical recording study using a voltage-sensitive dye. J Insect Physiol 46:877-886.
9. Galizia CG, Menzel R. 2001. The role of glomeruli in the neural representation of odours: results from optical recording studies. J Insect Physiol 47:115-129.
10. Galizia CG, Sachse S, Rappert A, Menzel R. 1999. The glomerular code for odor representation is species specific in the honeybee Apis mellifera. Nat Neurosci 5:473-478.
11. Gao Q, Chess A. 1999. Identification of candidate Drosophila olfactory receptors from genomic DNA sequence. Genomics 15:31-39.
12. Gao Q, Yuan B, Chess A. 2000. Convergent projections of Drosophila olfactory neurons to specific glomeruli in the antennal lobe. Nat Neurosci 3:780-785.
13. Gupta BP, Flores GV, Banerjee U, Rodrigues V. 1998. Prepatteming an epidermal field: Drosophila Lozenge, a member of the AML-1/Runt family of transcription factors, specifies olfactory sense organ type in a dose-dependent manner. Dev Biol 203:400-411.
14. Hansson BS, Ljungberg H, Hallberg E, Loftstedt C. 1992. Functional specialization of olfactory glomeruli in a moth. Science 29:1313-1315.
15. Jefferies GSXE, Marin EC, Stocker RF, Luo L. 2001. Target neuron prespecification in the olfactory map of Drosophila. Nature 414:204-208.
16. Jefferies GSXE, Marin EC, Watts R, Luo L. 2002. Development of neuronal connectivity in Drosophila antennal lobes and mushroom bodies. Curr Opin Neurobiol 12:80-86.
17. Jhaveri D, Rodrigues V. 2002. Sensory neurons of the Atonal lineage pioneer the formation of glomeruli within the adult Drosophila olfactory lobe. Development 129:1251-1260.
18. Jhaveri D, Sen A, Rodrigues V. 2000. Mechanisms underlying olfactory neuronal connectivity in Drosophila - the Atonal lineage organizes the periphery while sensory neurons and glia pattern the olfactory lobe. Dev Biol 226:73-87.
19. Laissue PP, Reiter C, Hiesinger PR, Halter S, Fischbach KF, Stocker RF. 1999. Three-dimensional reconstruction of the antennal lobe in Drosophila melanogaster. J Comp Neurol 22:543-552.
20. Malnic B, Hirono J, Sato T, Buck LB. 1999. Combinatorial receptor codes for odors. Cell 96:713-723.
21. Marin EC, Jeffereris GSXE, Komiyama T, Zhu H, Luo L. 2002. Representation of the glomerular olfactory map in the Drosophila brain. Cell 109:243-255.
22. Mombaerts P, Wang F, Dulac C, Chao SK, Nemes A, Mendelsohn M, Edmondson J, Axel R. 1996. Visualizing an olfactory sensory map. Cell 87:675-686.
23. Ressler KJ, Sullivan SL, Buck LB. 1994. Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb. Cell 79:1245-1255.
24. Rodrigues V. 1988. Spatial coding of olfactory information in the antennal lobe of Drosophila melanogaster. Brain Res 453:299-307.
25. Rodriguez I, Feinstein P, Mombaerts P. 1999. Variable pattern of axonal projections of sensory neurons in the mouse vomeronasal system. Cell 97:199-208.
26. Shanbhag SR, Müller B, Steinbrecht RA. 1999. Atlas of olfactory organs of Drosophila melanogaster. 1. Types, external organization, innervation and distribution of olfactory sensilla. Int J Insect Morphol Embryol 28:377-397.
27. Shymala BV, Chopra A. 1999. Drosophila melanogaster chemosensory and muscle development: identification and properties of a novel allele of scalloped and a new locus SG18.1, in a Ga14 enhancer trap screen. J Genet 78:87-97.
28. Stocker RF. 1994. The organization of the chemosensory system in Drosophila melanogaster: a review. Cell Tissue Res 275:3-26.
29. Stocker RF. 2001. Drosophila as a focus in olfactory research: Mapping of olfactory sensilla by fine structure, odor specificity, odorant receptor expression and central connectivity. Microcopy Res Tech 55:284-296.
30. Stocker RF, Lienhard MC, Borst A, Fischbach KF. 1990. Neuronal architecture of the antennal lobe in Drosophila melanogaster. Cell Tissue Res 262:9-34.
31. Stocker RF, Rodrigues V. 1999. Olfactory neurogenetics. In: Hansson BS, editor. Insect Olfaction. New York: Springer, p 283-314.
32. Stoertkuhl KF, Kettler R. 2001. Functional analysis of an olfactory receptor in Drosophila melanogaster. Proc Natl Acad Sci USA 98:9381-9385.
33. Treloar HB, Feinstein P, Mombaerts P, Greer CA. 2002. Specificity of glomerular targeting by olfactory sensory axon. J Neurosci 22:2469-2477.
34. Vassalli A, Rothman A, Feinstein P, Zapotocky M, Mombaerts P. 2002. Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb. Neuron 35:681-696.
35. Vassar R, Chao SK, Sitcheran R, Nunez JM, Vosshall LB, Axel R. 1994. Topographic organization of sensory projections to the olfactory bulb. Cell 74:309-318.
36. Vosshall LB. 2000. Olfaction in Drosophila. Curr Opin Neurobiol 10:498-503.
37. Vosshall LB, Amrein H, Morozov PS, Rzhetsky A, Axel R. 1999. A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96:725-736.
38. Vosshall LB, Wong AM, Axel R. 2000. An olfactory sensory map in the fly brain. Cell 102:147-159.
39. Wang F, Nemes A, Mendelsohn M, Axel R. 1998. Odorant receptors govem the formation of a precise topographic map. Cell 93:47-60.
40. Wetzel CH, Behrendt HJ, Gisselmann G, Stoertkuhl KF, Hovemann B, Hatt H. 2001. Functional expression and characterization of a Drosophila odorant receptor in a heterologous cell system. Proc Natl Acad Sci USA 98:9377-9380.
41. Wong AM, Wang JW, Axel R. 2002. Spatial representation of the glomerular map in the Drosophila protocerebrum. Cell 109:229-241.