Molecular determinants of ligand selectivity in a vertebrate odorant receptor

Journal of Neuroscience

Volumn 24, Issue 45, 2004, Pages 10128-10137

  Luu, Percy ^a,d   Acher, Francine ^b   Bertrand, Hugues Olivier ^c   Fan, Jiahong ^a,e   Ngai, John ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Accelrys SARL   (France)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Cytokinetics Inc   (United States)

Author keywords

G protein coupled receptor; Ligand binding; Odorant receptor; Olfaction; Olfactory; Signal transduction

Indexed keywords

AMINO ACID; G PROTEIN COUPLED RECEPTOR; LIGAND; METHIONINE;

AMINO ACID SUBSTITUTION; ARTICLE; CHEMICAL STRUCTURE; GOLDFISH; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; ZEBRA FISH;

AMINO ACIDS; ANIMALS; ARGININE; BINDING SITES; CALCIUM; CELL LINE; DNA, COMPLEMENTARY; GENE LIBRARY; GLYCINE; GOLDFISH; HUMANS; KIDNEY; LIGANDS; MODELS, MOLECULAR; MONTE CARLO METHOD; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ODORANT; RECOMBINANT FUSION PROTEINS; SPECIES SPECIFICITY; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; ZEBRAFISH PROTEINS;

EID: 8544260348     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3117-04.2004     Document Type: Article

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