Negative Feedback Regulation Ensures the One Receptor-One Olfactory Neuron Rule in Mouse

Science

Volumn 302, Issue 5653, 2003, Pages 2088-2094

  Serizawa, Shou ^a,b   Miyamichi, Kazunari ^a   Nakatani, Hiroko ^a   Suzuki, Misao ^c   Saito, Michiko ^d   Yoshihara, Yoshihiro ^d   Sakano, Hitoshi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c KUMAMOTO UNIVERSITY   (Japan)

^d RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; FEEDBACK; GENES; MUTAGENESIS;

FEEDBACK REGULATIONS; OLFACTORY SENSORY NEURONS;

NEUROLOGY;

DNA;

DNA; GENETICS; OLFACTION;

ARTICLE; FRAMESHIFT MUTATION; GENE CLUSTER; GENE EXPRESSION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OLFACTORY NERVOUS SYSTEM; OLFACTORY RECEPTOR; PRIORITY JOURNAL; PSEUDOGENE; RECEPTOR GENE; SENSORY RECEPTOR; TRANSGENE; TRANSGENIC MOUSE;

ALLELES; ANIMALS; AXONS; CHROMOSOMES, ARTIFICIAL, YEAST; CONSERVED SEQUENCE; FEEDBACK, BIOCHEMICAL; FRAMESHIFT MUTATION; GENE EXPRESSION REGULATION; GENE SILENCING; IN SITU HYBRIDIZATION; LOCUS CONTROL REGION; MICE; MICE, TRANSGENIC; MULTIGENE FAMILY; OLFACTORY BULB; OLFACTORY RECEPTOR NEURONS; PROMOTER REGIONS (GENETICS); PSEUDOGENES; RECEPTORS, ODORANT; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSGENES;

MUS MUSCULUS;

EID: 0346362447     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1089122     Document Type: Article

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30. Supported by the PRESTO and CREST programs of Japan Science and Technology Corporation and by grants from the Ministry of Education, Culture and Science of Japan. We thank R. Mitsumori, H. Kato, and H. Kimura for expert technical assistance and A. J. Otsuka and H. Sakano for critical reading of the manuscript.