-
1
-
-
9844229164
-
-
Technology Foresight London: HMSO
-
Technology foresight panel on health and life sciences. Progress through partnership Technology Foresight 4. London: HMSO, 1995:20-2.
-
(1995)
Progress Through Partnership
, vol.4
, pp. 20-22
-
-
-
3
-
-
0030038104
-
Replicative senescence: Implications for in vitro aging and tumor supression
-
Smith JR, Periera-Smith OM. Replicative senescence: implications for in vitro aging and tumor supression. Science 1996;273:63-7.
-
(1996)
Science
, vol.273
, pp. 63-67
-
-
Smith, J.R.1
Periera-Smith, O.M.2
-
4
-
-
0022330944
-
Genetics and ageing: The Werner syndrome as a segmental progeroid syndrome
-
Martin GM. Genetics and ageing: the Werner syndrome as a segmental progeroid syndrome. Adv Exp Biol Med 1985; 190:161-71.
-
(1985)
Adv Exp Biol Med
, vol.190
, pp. 161-171
-
-
Martin, G.M.1
-
5
-
-
0030447280
-
Human senescence
-
Kirkwood TBL. Human senescence. Bioessays 1996;18: 1009-16.
-
(1996)
Bioessays
, vol.18
, pp. 1009-1016
-
-
Kirkwood, T.B.L.1
-
6
-
-
0026484585
-
High blood pressure: Hunting the genes
-
Leckie BJ. High blood pressure: hunting the genes. Bioessays 1993;14:37-41.
-
(1993)
Bioessays
, vol.14
, pp. 37-41
-
-
Leckie, B.J.1
-
7
-
-
85012145261
-
Artificial activation of the growth in vitro of connective tissue
-
Carrel A. Artificial activation of the growth in vitro of connective tissue. J Exp Med 1913;16:14-19.
-
(1913)
J Exp Med
, vol.16
, pp. 14-19
-
-
Carrel, A.1
-
8
-
-
0344622606
-
The serial cultivation of human diploid fibroblast cell strains
-
Hayflick L, Moorehead PS. The serial cultivation of human diploid fibroblast cell strains. Exp Cell Res 1961;25:585-621.
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorehead, P.S.2
-
9
-
-
50549218525
-
The limited in vitro life-span of human diploid cell strains
-
Hayflick L. The limited in vitro life-span of human diploid cell strains. Exp Cell Res 1965;37:614-36.
-
(1965)
Exp Cell Res
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
10
-
-
0018634891
-
The cell biology of aging
-
Hayflick L. The cell biology of aging. J Invest Dermatol 1979;73:8-14.
-
(1979)
J Invest Dermatol
, vol.73
, pp. 8-14
-
-
Hayflick, L.1
-
11
-
-
0014816132
-
Replicative lifespan of cultivated human cells. Effects of donor's age, tissue and genotype
-
Martin GM, Sprague CA, Epstein CJ. Replicative lifespan of cultivated human cells. Effects of donor's age, tissue and genotype. Lab Invest 1970;23:86-92.
-
(1970)
Lab Invest
, vol.23
, pp. 86-92
-
-
Martin, G.M.1
Sprague, C.A.2
Epstein, C.J.3
-
12
-
-
0001068487
-
The relationship between in vitro cellular aging and in vivo human age
-
Schneider HL, Mitsui Y. The relationship between in vitro cellular aging and in vivo human age. Proc Natl Acad Sci 1976;73:3584-8.
-
(1976)
Proc Natl Acad Sci
, vol.73
, pp. 3584-3588
-
-
Schneider, H.L.1
Mitsui, Y.2
-
14
-
-
0023599999
-
The in vitro replicative potential and cellular morphology of human lens epithelial cells derived from different aged donors
-
Lipman RD, Taylor A. The in vitro replicative potential and cellular morphology of human lens epithelial cells derived from different aged donors. Curr Eye Res 1987;6:1453-7.
-
(1987)
Curr Eye Res
, vol.6
, pp. 1453-1457
-
-
Lipman, R.D.1
Taylor, A.2
-
15
-
-
0030988166
-
Matrix stimulates the proliferation of human corneal endothelial cells in culture
-
Blake DA, Yu H, Young DL, Caldwell DR. Matrix stimulates the proliferation of human corneal endothelial cells in culture. Invest Ophthmol Vis Sci 1997;38:1119-29.
-
(1997)
Invest Ophthmol Vis Sci
, vol.38
, pp. 1119-1129
-
-
Blake, D.A.1
Yu, H.2
Young, D.L.3
Caldwell, D.R.4
-
16
-
-
0024342791
-
Human T lymphocytes posess a limited in vitro lifespan
-
Perillo NL, Walford RL, Newman MA, Euros, RB. Human T lymphocytes posess a limited in vitro lifespan. Exp Gerontol 1987;24:177-8.
-
(1987)
Exp Gerontol
, vol.24
, pp. 177-178
-
-
Perillo, N.L.1
Walford, R.L.2
Newman, M.A.3
Euros, R.B.4
-
17
-
-
0020573584
-
Relationship between actinic damage and chronologic aging in keratinocyte cultures in human skin
-
Gilchrest BA. Relationship between actinic damage and chronologic aging in keratinocyte cultures in human skin. J Invest Dermatol 1983;81:184S-9S.
-
(1983)
J Invest Dermatol
, vol.81
-
-
Gilchrest, B.A.1
-
18
-
-
0000299214
-
Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo
-
Rohme D. Evidence for a relationship between longevity of mammalian species and life spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc Natl Acad Sci 1981;78: 5009-13.
-
(1981)
Proc Natl Acad Sci
, vol.78
, pp. 5009-5013
-
-
Rohme, D.1
-
19
-
-
0031037294
-
Long-term calorie restriction delays age-related decline in proliferation capacity of murine lens epithelial cells in vitro and in vivo
-
Li Y, Yan Q, Wolf NS. Long-term calorie restriction delays age-related decline in proliferation capacity of murine lens epithelial cells in vitro and in vivo. Invest Ophthmol Vis Sci 1997;38:100-8.
-
(1997)
Invest Ophthmol Vis Sci
, vol.38
, pp. 100-108
-
-
Li, Y.1
Yan, Q.2
Wolf, N.S.3
-
20
-
-
0027057374
-
Arteriosclerosis: Impairment of cellular interactions in the arterial wall
-
Van Hinsburgh VWM. Arteriosclerosis: impairment of cellular interactions in the arterial wall. Ann NY Acad Sci 1992;673:321-30.
-
(1992)
Ann NY Acad Sci
, vol.673
, pp. 321-330
-
-
Van Hinsburgh, V.W.M.1
-
22
-
-
0029164707
-
Cataloging altered gene expression in young and senescent cells using enhanced differential display
-
Linskens MHK, Feng J, Andrews WH, Enlow BE, Shahin MS, Tonkin LA, et al. Cataloging altered gene expression in young and senescent cells using enhanced differential display. Nucleic Acid Res 1995;23:3244-51.
-
(1995)
Nucleic Acid Res
, vol.23
, pp. 3244-3251
-
-
Linskens, M.H.K.1
Feng, J.2
Andrews, W.H.3
Enlow, B.E.4
Shahin, M.S.5
Tonkin, L.A.6
-
24
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri G, Lee X, Basile G, Acosta M, Scott G, Roskelly C, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci 1995; 92:9362-7.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 9362-9367
-
-
Dimri, G.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelly, C.6
-
25
-
-
0013918813
-
The division cycle and RNA synthesis in diploid human cells at different passage levels in vitro
-
Maciera-Coelho A, Ponten J, Philipson L. The division cycle and RNA synthesis in diploid human cells at different passage levels in vitro. Exp Cell Res 1966;42:673-684.
-
(1966)
Exp Cell Res
, vol.42
, pp. 673-684
-
-
Maciera-Coelho, A.1
Ponten, J.2
Philipson, L.3
-
26
-
-
0015580671
-
Cellular senescence and DNA synthesis
-
Cristofalo VJ, Scharf BB. Cellular senescence and DNA synthesis. Exp Cell Res 1973;76:419-27.
-
(1973)
Exp Cell Res
, vol.76
, pp. 419-427
-
-
Cristofalo, V.J.1
Scharf, B.B.2
-
27
-
-
0018890645
-
Intraclonal variation in proliferative potential of human diploid fibroblasts: Stochastic mechanism for cellular ageing
-
Smith JR, Whitney RG. Intraclonal variation in proliferative potential of human diploid fibroblasts: stochastic mechanism for cellular ageing. Science 1980;207:82-4.
-
(1980)
Science
, vol.207
, pp. 82-84
-
-
Smith, J.R.1
Whitney, R.G.2
-
28
-
-
0021058256
-
A quantitative analysis of the ageing of human glial cells in culture
-
Ponten J, Stein WD, Shall S. A quantitative analysis of the ageing of human glial cells in culture. J Cell Physiol 1983;117:342-52.
-
(1983)
J Cell Physiol
, vol.117
, pp. 342-352
-
-
Ponten, J.1
Stein, W.D.2
Shall, S.3
-
29
-
-
0018377134
-
A mortalisation theory for the control of cell proliferation and for the origin of immortal cell lines
-
Shall S, Stein WD. A mortalisation theory for the control of cell proliferation and for the origin of immortal cell lines. J Theoret Biol 1979;76:219-31.
-
(1979)
J Theoret Biol
, vol.76
, pp. 219-231
-
-
Shall, S.1
Stein, W.D.2
-
30
-
-
0001173605
-
Mortalisation or reproductive sterility of animal cells in culture
-
Potten CS, ed. Oxford: Oxford University Press
-
Shall S. Mortalisation or reproductive sterility of animal cells in culture. In: Potten CS, ed. Perspectives on mammalian cell death. Oxford: Oxford University Press, 1987:184-201.
-
(1987)
Perspectives on Mammalian Cell Death
, pp. 184-201
-
-
Shall, S.1
-
31
-
-
0015811623
-
Attempted hydridisations with senescent human nbroblasts
-
Littlefield JW. Attempted hydridisations with senescent human nbroblasts. J Cell Physiol 1973;82:129-32.
-
(1973)
J Cell Physiol
, vol.82
, pp. 129-132
-
-
Littlefield, J.W.1
-
32
-
-
0000547195
-
Aging at the cellular level: The human fibroblast-like cell model
-
Schneider EL, Rowe JW, eds. San Diego: Academic Press Inc
-
Norwood TH, Smith JR, Stein GH. Aging at the cellular level: the human fibroblast-like cell model. In: Schneider EL, Rowe JW, eds. Handbook of the biology of aging. San Diego: Academic Press Inc, 1990:131-54.
-
(1990)
Handbook of the Biology of Aging
, pp. 131-154
-
-
Norwood, T.H.1
Smith, J.R.2
Stein, G.H.3
-
33
-
-
0025217463
-
Genetic and molecular studies of cellular immortalisation
-
Smith JR, Periera-Smith OM. Genetic and molecular studies of cellular immortalisation. Adv Cancer Res 1990;54:63-77.
-
(1990)
Adv Cancer Res
, vol.54
, pp. 63-77
-
-
Smith, J.R.1
Periera-Smith, O.M.2
-
34
-
-
0028342664
-
Cloning of senescent cell derived inhibitors of DNA synthesis using an expression screen
-
Noda A, Ning Y, Venable SF, Periera-Smith OM, Smith JR. Cloning of senescent cell derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 1994;211:90-8.
-
(1994)
Exp Cell Res
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Periera-Smith, O.M.4
Smith, J.R.5
-
35
-
-
0029317383
-
1 arrest in senescent human fibroblasts
-
1 arrest in senescent human fibroblasts. Bioessays 1995;17:537-43.
-
(1995)
Bioessays
, vol.17
, pp. 537-543
-
-
Stein, G.H.1
Dulic, V.2
-
36
-
-
0030964277
-
The biology of replicative senescence
-
Campisi J. The biology of replicative senescence. Eur J Cancer 1997;33:703-10.
-
(1997)
Eur J Cancer
, vol.33
, pp. 703-710
-
-
Campisi, J.1
-
37
-
-
0031127177
-
Cyclins, cyclin dependent kinases and differentiation
-
Gao CY, Zelenka PS. Cyclins, cyclin dependent kinases and differentiation. Bioessays 1997;19:207-315.
-
(1997)
Bioessays
, vol.19
, pp. 207-315
-
-
Gao, C.Y.1
Zelenka, P.S.2
-
38
-
-
0001214436
-
Distinction between differentiation and senescence and the abscence of increased apoptosis in human keratinocytes undergoing cellular ageing in vitro
-
Norsgaard H, Clark BFC, Rattan SIS. Distinction between differentiation and senescence and the abscence of increased apoptosis in human keratinocytes undergoing cellular ageing in vitro. Exp Gerontol 1996;31:655-68.
-
(1996)
Exp Gerontol
, vol.31
, pp. 655-668
-
-
Norsgaard, H.1
Clark, B.F.C.2
Rattan, S.I.S.3
-
39
-
-
0003893135
-
-
Oxford: Oxford University Press
-
Kipling D. The telomere. Oxford: Oxford University Press, 1995.
-
(1995)
The Telomere
-
-
Kipling, D.1
-
40
-
-
0002309826
-
Telomere dynamics and genome instability in human cancer
-
Blackburn EH, Greider CW, eds. New York: Cold Spring Harbor Press
-
de Lange T. Telomere dynamics and genome instability in human cancer. In: Blackburn EH, Greider CW, eds. Telomeres New York: Cold Spring Harbor Press, 1995:265-93.
-
(1995)
Telomeres
, pp. 265-293
-
-
De Lange, T.1
-
42
-
-
0025279931
-
Telomeres shorten during ageing of human fibroblasts
-
Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990;345:458-60.
-
(1990)
Nature
, vol.345
, pp. 458-460
-
-
Harley, C.B.1
Futcher, A.B.2
Greider, C.W.3
-
43
-
-
0030006735
-
In situ analysis of changes in telomere size during replicative aging and cell transformation
-
Henderson S, Allsopp R, Spector D, Wang SS, Harley C. In situ analysis of changes in telomere size during replicative aging and cell transformation. J Cell Biol 1996;134:1-12.
-
(1996)
J Cell Biol
, vol.134
, pp. 1-12
-
-
Henderson, S.1
Allsopp, R.2
Spector, D.3
Wang, S.S.4
Harley, C.5
-
44
-
-
0030447657
-
The Saccharomyces CDC13 protein is a single-stranded TG telomeric DNA-binding protein in vitro that affects telomere behavior in vivo
-
Lin JJ, Zakian VA. The Saccharomyces CDC13 protein is a single-stranded TG telomeric DNA-binding protein in vitro that affects telomere behavior in vivo. Proc Natl Acad Sci USA 1996;93:13760-5.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13760-13765
-
-
Lin, J.J.1
Zakian, V.A.2
-
45
-
-
0025143252
-
Telomere reduction in human colorectal carcinoma and with ageing
-
Hastie ND, Dempster M, Dunlop MG, Thompson AM, Green DK, Allshire RC. Telomere reduction in human colorectal carcinoma and with ageing. Nature 1990;346: 866-8.
-
(1990)
Nature
, vol.346
, pp. 866-868
-
-
Hastie, N.D.1
Dempster, M.2
Dunlop, M.G.3
Thompson, A.M.4
Green, D.K.5
Allshire, R.C.6
-
46
-
-
0026452286
-
Loss of transcription factor AP1 DNA binding activity during lymphocyte aging in vivo
-
Sikora E, Kaminska B, Radziszewska E, Kaczmarek L. Loss of transcription factor AP1 DNA binding activity during lymphocyte aging in vivo. FEBS Lett 1992;312:179-82.
-
(1992)
FEBS Lett
, vol.312
, pp. 179-182
-
-
Sikora, E.1
Kaminska, B.2
Radziszewska, E.3
Kaczmarek, L.4
-
47
-
-
0025052004
-
Repression of c-fos and an altered genetic programme in senescent human fibroblasts
-
Sheshadri T, Campisi J. Repression of c-fos and an altered genetic programme in senescent human fibroblasts. Science 1990;247:205-9.
-
(1990)
Science
, vol.247
, pp. 205-209
-
-
Sheshadri, T.1
Campisi, J.2
-
49
-
-
4243305752
-
Senescence and immortalisation of human cells
-
Studzinski, GP, ed. Oxford: IRL Press
-
Hubbard K, Ozer HL. Senescence and immortalisation of human cells. In: Studzinski, GP, ed. Cell growth and apoptosis: a practical approach. Oxford: IRL Press, 1995: 229-49.
-
(1995)
Cell Growth and Apoptosis: A Practical Approach
, pp. 229-249
-
-
Hubbard, K.1
Ozer, H.L.2
-
50
-
-
0025130530
-
Senescent human diploid fibroblasts are able to support DNA synthesis and to express markers associated with proliferation
-
Kill IR, Shall S. Senescent human diploid fibroblasts are able to support DNA synthesis and to express markers associated with proliferation. J Cell Sci 1990;97:473-8.
-
(1990)
J Cell Sci
, vol.97
, pp. 473-478
-
-
Kill, I.R.1
Shall, S.2
-
51
-
-
0027300829
-
In vitro aging in T lymphocyte cultures: Analysis of DNA content and cell size
-
Perillo NL, Naeim F, Walford RL, Effros RB. In vitro aging in T lymphocyte cultures: analysis of DNA content and cell size. Exp Cell Res 1993;207:131-5.
-
(1993)
Exp Cell Res
, vol.207
, pp. 131-135
-
-
Perillo, N.L.1
Naeim, F.2
Walford, R.L.3
Effros, R.B.4
-
52
-
-
0024398094
-
Collagenase production by early and late passage cultures of human fibroblasts
-
Millis AJT, Sottile J, Hoyle M, Mann DM, Diemer V. Collagenase production by early and late passage cultures of human fibroblasts. Exp Gerontol 1989;24:559-75.
-
(1989)
Exp Gerontol
, vol.24
, pp. 559-575
-
-
Millis, A.J.T.1
Sottile, J.2
Hoyle, M.3
Mann, D.M.4
Diemer, V.5
-
53
-
-
0028338836
-
Expression of 72Kd gelatinase and TIMP2 in early and late passage human fibroblasts
-
Zeng G, Millis AJ. Expression of 72Kd gelatinase and TIMP2 in early and late passage human fibroblasts. Exp Cell Res 1994;213:148-55.
-
(1994)
Exp Cell Res
, vol.213
, pp. 148-155
-
-
Zeng, G.1
Millis, A.J.2
-
54
-
-
0029962187
-
Altered expression of plasminogen activator and plasminogen act ivator inhibitor during cellular senescence
-
West MD, Shay JW, Wright WE, Linskens MHK. Altered expression of plasminogen activator and plasminogen act ivator inhibitor during cellular senescence. Exp Gerontol 1996;31:175-93.
-
(1996)
Exp Gerontol
, vol.31
, pp. 175-193
-
-
West, M.D.1
Shay, J.W.2
Wright, W.E.3
Linskens, M.H.K.4
-
55
-
-
0029562453
-
Role of ceramide in cell senescence
-
Venable ME, Lee JY, Smyth MJ, Bielawska A, Obeid LM. Role of ceramide in cell senescence. J Biol Chem 1995;270: 30701-8.
-
(1995)
J Biol Chem
, vol.270
, pp. 30701-30708
-
-
Venable, M.E.1
Lee, J.Y.2
Smyth, M.J.3
Bielawska, A.4
Obeid, L.M.5
-
56
-
-
0027295499
-
Failure of senescent human fibroblasts to express the insulin-like growth factor 1 gene
-
Ferber A, Chang CD, Sell C, Ptasznik A, Cristofalo VJ, Hubbard K, et al. Failure of senescent human fibroblasts to express the insulin-like growth factor 1 gene. J Biol Chem 1993;268:17883-8.
-
(1993)
J Biol Chem
, vol.268
, pp. 17883-17888
-
-
Ferber, A.1
Chang, C.D.2
Sell, C.3
Ptasznik, A.4
Cristofalo, V.J.5
Hubbard, K.6
-
57
-
-
0028214727
-
Supression of calcium dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein
-
Liu S, Thweatt R, Lumpkin CK, Goldstein S. Supression of calcium dependent membrane currents in human fibroblasts by replicative senescence and forced expression of a gene sequence encoding a putative calcium-binding protein. Proc Natl Acad Sci USA 1994;91:2186-90.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2186-2190
-
-
Liu, S.1
Thweatt, R.2
Lumpkin, C.K.3
Goldstein, S.4
-
58
-
-
0030042853
-
Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts
-
Zeng G, Millis AJT. Differential regulation of collagenase and stromelysin mRNA in late passage cultures of human fibroblasts. Exp Cell Res 1996;222:150-6.
-
(1996)
Exp Cell Res
, vol.222
, pp. 150-156
-
-
Zeng, G.1
Millis, A.J.T.2
-
59
-
-
0026753051
-
Cloning and expressionof SAG: A novel marker of cellular senescence
-
Wistrom C, Villeponteau B. Cloning and expressionof SAG: a novel marker of cellular senescence. Exp Cell Res 1992;199:355-62.
-
(1992)
Exp Cell Res
, vol.199
, pp. 355-362
-
-
Wistrom, C.1
Villeponteau, B.2
-
60
-
-
0029116174
-
Elevated expression of mitochondrial cytochrome b and NADH dehydrogenase subunit 4/4L in senescent human cells
-
Kodama S, Yamada H, Annab L, Barrett JC. Elevated expression of mitochondrial cytochrome b and NADH dehydrogenase subunit 4/4L in senescent human cells. Exp Cell Res 1995;219:82-6.
-
(1995)
Exp Cell Res
, vol.219
, pp. 82-86
-
-
Kodama, S.1
Yamada, H.2
Annab, L.3
Barrett, J.C.4
-
61
-
-
0021783284
-
Progeria: A model disease for the study of accelerated ageing
-
Brown WT, Zebrower M, Kieras F. Progeria: a model disease for the study of accelerated ageing. Basic Life Sci 1984;35:375-96.
-
(1984)
Basic Life Sci
, vol.35
, pp. 375-396
-
-
Brown, W.T.1
Zebrower, M.2
Kieras, F.3
-
62
-
-
0028156003
-
Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes
-
Weirich-Schwaiger H, Weirich HG, Gruber B, Schweiger, M, Hirsch-Kaufmann M. Correlation between senescence and DNA repair in cells from young and old individuals and in premature aging syndromes. Mutat Res 1994;31:37-48.
-
(1994)
Mutat Res
, vol.31
, pp. 37-48
-
-
Weirich-Schwaiger, H.1
Weirich, H.G.2
Gruber, B.3
Schweiger, M.4
Hirsch-Kaufmann, M.5
-
63
-
-
0021171248
-
Werner's syndrome: An under-diagnosed condition resembling premature aging
-
Tollefsbul TO, Cohen HJ. Werner's syndrome: An under-diagnosed condition resembling premature aging. Age 1984;7:75-88.
-
(1984)
Age
, vol.7
, pp. 75-88
-
-
Tollefsbul, T.O.1
Cohen, H.J.2
-
64
-
-
0027377887
-
Werner's syndrome: A review of the clinical and pathological features and pathogenesis
-
Herd RM, Faragher RGA, Shall S, Hunter JAA. Werner's syndrome: a review of the clinical and pathological features and pathogenesis. Eur J Dermatol 1993;3:425-32.
-
(1993)
Eur J Dermatol
, vol.3
, pp. 425-432
-
-
Herd, R.M.1
Faragher, R.G.A.2
Shall, S.3
Hunter, J.A.A.4
-
65
-
-
0019444282
-
Systematic growth studies, cocultivation and cell hybridisation studies of Werner syndrome cultured skin fibroblasts
-
Salk D, Bryant E, Au K, Hoehn H, Martin GM. Systematic growth studies, cocultivation and cell hybridisation studies of Werner syndrome cultured skin fibroblasts. Hum Genet 1981;58:310-16.
-
(1981)
Hum Genet
, vol.58
, pp. 310-316
-
-
Salk, D.1
Bryant, E.2
Au, K.3
Hoehn, H.4
Martin, G.M.5
-
66
-
-
0027144126
-
Is the Werner's syndrome gene a "clock" gene which counts cell division?
-
Faragher RGA, Kill IR, Tannock TCA, Hunter JAA, Shall S. Is the Werner's syndrome gene a "clock" gene which counts cell division? Proc Natl Acad Sci 1993;90:12030-34.
-
(1993)
Proc Natl Acad Sci
, vol.90
, pp. 12030-12034
-
-
Faragher, R.G.A.1
Kill, I.R.2
Tannock, T.C.A.3
Hunter, J.A.A.4
Shall, S.5
-
67
-
-
0028295472
-
The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture
-
Kill IR, Faragher RGA, Lawrence K, Shall S. The expression of proliferation-dependent antigens during the lifespan of normal and progeroid human fibroblasts in culture. J Cell Sci 1994;107:571-9.
-
(1994)
J Cell Sci
, vol.107
, pp. 571-579
-
-
Kill, I.R.1
Faragher, R.G.A.2
Lawrence, K.3
Shall, S.4
-
68
-
-
0025169778
-
Increased frequency of 6-thioguanine resistant peripheral blood lymphocytes in Werner syndrome patients
-
Fukuchi K, Tanaka K, Kumahara Y, Maramo K, Pride M, Martin GM, et al. Increased frequency of 6-thioguanine resistant peripheral blood lymphocytes in Werner syndrome patients. Hum Genet 1990;84:249-52.
-
(1990)
Hum Genet
, vol.84
, pp. 249-252
-
-
Fukuchi, K.1
Tanaka, K.2
Kumahara, Y.3
Maramo, K.4
Pride, M.5
Martin, G.M.6
-
69
-
-
0024465870
-
Mutator phenotype of Werner syndrome is characterised by extensive deletions
-
Fukuchi K, Martin GM, Monnat RJ. Mutator phenotype of Werner syndrome is characterised by extensive deletions. Proc Natl Acad Sci USA 1989;86:5893-7.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5893-5897
-
-
Fukuchi, K.1
Martin, G.M.2
Monnat, R.J.3
-
70
-
-
0026502062
-
Genetic linkage of Werner's syndrome to five markers on chromosome 8
-
Goto M, Rubenstein M, Weber J, Woods K, Drayna D. Genetic linkage of Werner's syndrome to five markers on chromosome 8. Nature 1992;355:735-7.
-
(1992)
Nature
, vol.355
, pp. 735-737
-
-
Goto, M.1
Rubenstein, M.2
Weber, J.3
Woods, K.4
Drayna, D.5
-
71
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu CE, Oshima J, Ying-Hui F, Wijsman EM, Hisami F, Alisch R, et al. Positional cloning of the Werner's syndrome gene. Science 1996;272:258-62.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.E.1
Oshima, J.2
Ying-Hui, F.3
Wijsman, E.M.4
Hisami, F.5
Alisch, R.6
-
72
-
-
16944366241
-
Mutations in the consensus helicase domains of the Werner syndrome gene
-
Yu CE, Oshima J, Wijsman EM, Nakura J, Aliki T, Piussan C, et al. Mutations in the consensus helicase domains of the Werner syndrome gene. Am J Hum Genet 1997;60:330-41.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 330-341
-
-
Yu, C.E.1
Oshima, J.2
Wijsman, E.M.3
Nakura, J.4
Aliki, T.5
Piussan, C.6
-
73
-
-
0029922445
-
Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts
-
Lecka-Czernik B, Moerman EJ, Jones RA, Goldstein S. Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts. Exp Gerontol 1996;31:159-74.
-
(1996)
Exp Gerontol
, vol.31
, pp. 159-174
-
-
Lecka-Czernik, B.1
Moerman, E.J.2
Jones, R.A.3
Goldstein, S.4
-
74
-
-
0025866760
-
Diverse gene sequences are overexpressed in Werner syndrome fibroblasts undergoing premature replicative senescence
-
Murano S, Thweatt R, Schmookler-Reis RJ, Jones RA, Moerman EJ, Goldstein S. Diverse gene sequences are overexpressed in Werner syndrome fibroblasts undergoing premature replicative senescence. Mol Cell Biol 1991;11: 3905-14.
-
(1991)
Mol Cell Biol
, vol.11
, pp. 3905-3914
-
-
Murano, S.1
Thweatt, R.2
Schmookler-Reis, R.J.3
Jones, R.A.4
Moerman, E.J.5
Goldstein, S.6
-
75
-
-
0027621137
-
Werner syndrome and biological ageing: A molecular genetic hypothesis
-
Thweatt R, Goldstein S. Werner syndrome and biological ageing: a molecular genetic hypothesis. Bioessays 1993;15: 421-6.
-
(1993)
Bioessays
, vol.15
, pp. 421-426
-
-
Thweatt, R.1
Goldstein, S.2
-
76
-
-
0031585872
-
Cycling Werner's syndrome fibroblasts display calcium dependent potassium currents
-
Faragher RGA, Hardy S, Dropcova S, Allen MC. Cycling Werner's syndrome fibroblasts display calcium dependent potassium currents. Exp Cell Res 1997;231:119-22.
-
(1997)
Exp Cell Res
, vol.231
, pp. 119-122
-
-
Faragher, R.G.A.1
Hardy, S.2
Dropcova, S.3
Allen, M.C.4
-
78
-
-
0028898823
-
Regulation of c-fos in senescing Werner syndrome fibroblasts differs from that seen in senescing fibroblasts from normal donors
-
Oshima J, Campisi J, Tannock CA, Martin GM. Regulation of c-fos in senescing Werner syndrome fibroblasts differs from that seen in senescing fibroblasts from normal donors. J Cell Physiol 1995;162:277-83.
-
(1995)
J Cell Physiol
, vol.162
, pp. 277-283
-
-
Oshima, J.1
Campisi, J.2
Tannock, C.A.3
Martin, G.M.4
-
79
-
-
0011555560
-
Correlation between deoxyribonucleic acid excision repair and life-span in a number of mammalian species
-
Hart RW, Setow RB. Correlation between deoxyribonucleic acid excision repair and life-span in a number of mammalian species. Proc Natl Acad Sci USA 1974;71:2169-73.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 2169-2173
-
-
Hart, R.W.1
Setow, R.B.2
-
80
-
-
0018195078
-
Normal level of unscheduled DNA synthesis in Werner's syndrome fibroblasts in culture
-
Higashikawa T, Fujiwara Y. Normal level of unscheduled DNA synthesis in Werner's syndrome fibroblasts in culture. Exp Cell Res 1978;113:438-41.
-
(1978)
Exp Cell Res
, vol.113
, pp. 438-441
-
-
Higashikawa, T.1
Fujiwara, Y.2
-
81
-
-
0023712434
-
Spontaneous and induced chromosomal instability in Werner's syndrome
-
Gebhart E, Baur R, Raub U, Schinzel M, Ruprecht KW, Jonas JB. Spontaneous and induced chromosomal instability in Werner's syndrome. Hum Genet 1988;80:135-9.
-
(1988)
Hum Genet
, vol.80
, pp. 135-139
-
-
Gebhart, E.1
Baur, R.2
Raub, U.3
Schinzel, M.4
Ruprecht, K.W.5
Jonas, J.B.6
-
82
-
-
0029944713
-
DNA repair fine structure in Werner's syndrome cell lines
-
Webb DK, Evans MK, Bohr VA. DNA repair fine structure in Werner's syndrome cell lines. Exp Cell Res 1996;224: 272-8.
-
(1996)
Exp Cell Res
, vol.224
, pp. 272-278
-
-
Webb, D.K.1
Evans, M.K.2
Bohr, V.A.3
-
83
-
-
0025159160
-
Immune function, mutant frequency and cancer risk in the DNA repair defective genodermatoses xeroderma pigmentosum, cockaynes syndrome and trichthiodystrophy
-
Norris PG, Limb A, Hamblm AS, Lehmann AR, Arlett CF, Cole J, et al. Immune function, mutant frequency and cancer risk in the DNA repair defective genodermatoses xeroderma pigmentosum, cockaynes syndrome and trichthiodystrophy. J Invest Dermatol 1990;94:94-9.
-
(1990)
J Invest Dermatol
, vol.94
, pp. 94-99
-
-
Norris, P.G.1
Limb, A.2
Hamblm, A.S.3
Lehmann, A.R.4
Arlett, C.F.5
Cole, J.6
-
84
-
-
0030476278
-
Werner's syndrome: Entering the helicase era
-
Epstein CJ, Motulsky AG. Werner's syndrome: entering the helicase era. Biocssays 1996;18:1025-7.
-
(1996)
Biocssays
, vol.18
, pp. 1025-1027
-
-
Epstein, C.J.1
Motulsky, A.G.2
-
85
-
-
0020066520
-
Failure of RNA synthesis to recover after UV irradiation: An early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum
-
Mayne LV, Lehmann AR. Failure of RNA synthesis to recover after UV irradiation: an early defect in cells from individuals with Cockayne's syndrome and xeroderma pigmentosum. Cancer Res 1982;42:1473-8.
-
(1982)
Cancer Res
, vol.42
, pp. 1473-1478
-
-
Mayne, L.V.1
Lehmann, A.R.2
-
86
-
-
0026545430
-
Xeroderma pigmentosum and Cockayne syndrome: Overlapping clinical and biochemical phenotypes
-
Greenhaw GA, Hebert A, Duke-Woodside ME, Butler IJ, Hecht JT, Cleaver JE, et al. Xeroderma pigmentosum and Cockayne syndrome: overlapping clinical and biochemical phenotypes. Am J Hum Genet 1992;50:677-89.
-
(1992)
Am J Hum Genet
, vol.50
, pp. 677-689
-
-
Greenhaw, G.A.1
Hebert, A.2
Duke-Woodside, M.E.3
Butler, I.J.4
Hecht, J.T.5
Cleaver, J.E.6
-
87
-
-
0025852337
-
Bloom syndrome and Ataxia telangiectasia
-
Llerena JC, Murer-Orlando. Bloom syndrome and Ataxia telangiectasia. Semin Hematol 1991;28:95-103.
-
(1991)
Semin Hematol
, vol.28
, pp. 95-103
-
-
Llerena, J.C.1
Murer-Orlando2
-
88
-
-
0026460896
-
Telomere length predicts replicative capacity of human fibroblasts
-
Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, et al. Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 1992;89:10114-18.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10114-10118
-
-
Allsopp, R.C.1
Vaziri, H.2
Patterson, C.3
Goldstein, S.4
Younglai, E.V.5
Futcher, A.B.6
-
89
-
-
0029145379
-
Evidence for a critical telomere length in senescent human fibroblasts
-
Allsopp RC, Harley CB. Evidence for a critical telomere length in senescent human fibroblasts. Exp Cell Res 1995;219:130-6.
-
(1995)
Exp Cell Res
, vol.219
, pp. 130-136
-
-
Allsopp, R.C.1
Harley, C.B.2
-
90
-
-
0029156035
-
Telomere shortening is associated with cell division in vitro and in vivo
-
Allsopp RC, Chang E, Kashefi-Aazam M, Rogaev EI, Piatyszek MA, Shay JW, et al. Telomere shortening is associated with cell division in vitro and in vivo. Exp Cell Res 1995;220:194-200.
-
(1995)
Exp Cell Res
, vol.220
, pp. 194-200
-
-
Allsopp, R.C.1
Chang, E.2
Kashefi-Aazam, M.3
Rogaev, E.I.4
Piatyszek, M.A.5
Shay, J.W.6
-
91
-
-
0030944985
-
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
-
Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997;88:593-602.
-
(1997)
Cell
, vol.88
, pp. 593-602
-
-
Serrano, M.1
Lin, A.W.2
McCurrach, M.E.3
Beach, D.4
Lowe, S.W.5
-
92
-
-
0029971241
-
Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells
-
Schulz VP, Zakian VA, Ogburn CE, McKay J, Jarzebowicz AA, Edland SD, et al. Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells. Hum Genet 1996;97:750-4.
-
(1996)
Hum Genet
, vol.97
, pp. 750-754
-
-
Schulz, V.P.1
Zakian, V.A.2
Ogburn, C.E.3
McKay, J.4
Jarzebowicz, A.A.5
Edland, S.D.6
-
93
-
-
0029681361
-
Accelerated telomere shortening in ataxia telangiectasia
-
Metcalfe JA, Parkhill J, Campbell L, Stacey M, Biggs P, Byrd PJ, et al. Accelerated telomere shortening in ataxia telangiectasia. Nature Genet 1996;13:350-3.
-
(1996)
Nature Genet
, vol.13
, pp. 350-353
-
-
Metcalfe, J.A.1
Parkhill, J.2
Campbell, L.3
Stacey, M.4
Biggs, P.5
Byrd, P.J.6
-
94
-
-
0029778901
-
Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent
-
Ogryzku W, Hirai TH, Russanova VR, Barbie DA, Howard BH. Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. Mol Cell Biol 1996;16:5210-18.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5210-5218
-
-
Ogryzku, W.1
Hirai, T.H.2
Russanova, V.R.3
Barbie, D.A.4
Howard, B.H.5
-
96
-
-
0028822203
-
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint
-
Garvik B, Carson M, Hartwell L. Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint. Mol Cell Biol 1995;15:6128-38.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6128-6138
-
-
Garvik, B.1
Carson, M.2
Hartwell, L.3
-
97
-
-
0031029001
-
Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13
-
Grandin N, Reed SI, Charbonneau M. Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13. Genes Der 1997;11: 512-27.
-
(1997)
Genes der
, vol.11
, pp. 512-527
-
-
Grandin, N.1
Reed, S.I.2
Charbonneau, M.3
-
98
-
-
0029845892
-
Cdc13p: A single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance
-
Nugent CI, Hughes TR, Lue NF, Lundblad V. Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance. Science 1996;274:249-52.
-
(1996)
Science
, vol.274
, pp. 249-252
-
-
Nugent, C.I.1
Hughes, T.R.2
Lue, N.F.3
Lundblad, V.4
-
99
-
-
0028882869
-
Yeast checkpoint genes in DNA damage processing: Implications for repair and arrest
-
Lydall D, Weinert T. Yeast checkpoint genes in DNA damage processing: implications for repair and arrest. Science 1995;270:1488-91.
-
(1995)
Science
, vol.270
, pp. 1488-1491
-
-
Lydall, D.1
Weinert, T.2
-
100
-
-
0031000884
-
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
-
Makarov VL, Hirose Y, Langmore JP. Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell 1997;88: 657-66.
-
(1997)
Cell
, vol.88
, pp. 657-666
-
-
Makarov, V.L.1
Hirose, Y.2
Langmore, J.P.3
-
101
-
-
0029127226
-
Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: A model for senescence?
-
von Zglinicki T, Saretzki G, Döcke W, Lotze C. Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp Cell Res 1995;220: 186-93.
-
(1995)
Exp Cell Res
, vol.220
, pp. 186-193
-
-
Von Zglinicki, T.1
Saretzki, G.2
Döcke, W.3
Lotze, C.4
|