Senescent terminal weight loss in the male F344 rat

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 284, Issue 2 53-2, 2003, Pages

  Black Jr , Bill J ^a   McMahan, C Alex ^a   Masoro, Edward J ^b   Ikeno, Yuji ^b,c   Katz, Michael S ^a,c  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Caloric restriction; Food intake; Hypothalamic function

Indexed keywords

ADOLESCENT; AGED; ANIMAL EXPERIMENT; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; FOOD INTAKE; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENESCENCE; WEIGHT REDUCTION;

EID: 0037304202     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00640.2001     Document Type: Article

References (33)

1. Beckman KB and Ames BN. Mitochondrial aging: open questions. Ann NY Acad Sci 854: 118-127, 1998.
2. Bertrand HA, Lynd FT, Masoro EJ, and Yu BP. Changes in adipose mass and cellularity through the adult life of rats fed ad libitum or a life-prolonging restricted diet. J Gerontol 35: 827-835, 1980.
3. Blanton CA, Horwitz BA, Blevins JE, Hamilton JS, Hernandez EJ, and McDonald RB. Reduced feeding response to neuropeptide Y in senescent Fischer 344 rats. Am J Physiol Regul Integr Comp Physiol 280: R1052-R1060, 2001.
4. Blanton CA, Horwitz BA, and McDonald RB. Neurochemical alterations during age-related anorexia. Proc Soc Exp Biol Med 221: 153-165, 1999.
5. Blanton CA, Horwitz BA, Murtagh-Mark C, Gietzen DW, Griffey SM, and McDonald RB. Meal patterns associated with the age-related decrease in food intake in the Fischer 344 rat. Am J Physiol Regul Integr Comp Physiol 275: R1494-R1502, 1998.
6. Buck M, Zhang L, Halasz NA, Hunter T, and Chojkier M. Nuclear export of phosphorylated C/EBPβ mediates the inhibition of albumin expression by TNF-α. EMBO J 20: 6712-6723, 2001.
7. Chapman IM, MacIntosh CG, Morley JE, and Horowitz M. The anorexia of ageing. Biogerontology 3: 67-71, 2001.
8. Clarkston WK, Pantano MM, Morley JE, Horowitz M, Littlefield JM, and Burton FR. Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults. Am J Physiol Regul Integr Comp Physiol 272: R243-R248, 1997.
9. Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, and Friedman JM. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science 297: 240-243, 2002.
10. Cupples WA. Regulation of body weight. Am J Physiol Regul Integr Comp Physiol 282: R1264-R1266, 2002.
11. Fried LP and Walston J. Frailty and failure to thrive. In: Principles of Geriatric Medicine and Gerontology (3rd ed.), edited by Hazzard WR, Blass JP, Ettinger WH, Halter JB, and Ouslander JG. New York: McGraw-Hill, 1999, p. 1387-1402.
12. Gross AJ and Clark VA. Survival Distributions: Reliability Applications in the Biomedical Sciences. New York: Wiley, 1975.
13. Harper EJ. Changing perspectives on aging and energy requirements: aging and digestive function in humans, dogs and cats. J Nutr 128: 2632S-2635S, 1998.
14. Holt PR. The gastrointestinal tract. In: Handbook of Physiology. Aging. Bethesda, MD: Am. Physiol. Soc., 1995, sect. 11, chapt. 20, p. 505-554.
15. Lecker SH, Solomon V, Mitch WE, and Goldberg AL. Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease states. J Nutr 129: 227S-237S, 1999.
16. Maeda H, Gleiser CA, Masoro EJ, Murata I, McMahan CA, and Yu BP. Nutritional influences on aging of Fischer 344 rats. II. Pathology. J Gerontol 40: 671-688, 1985.
17. Masoro EJ. Dietary restriction: an experimental approach to the study of the biology of aging. In: Handbook of the Biology of Aging (5th ed), edited by Masoro EJ and Austad SN. San Diego, CA: Academic, 2001, p. 396-420.
18. Masoro EJ, Iwasaki K, Gleiser CA, McMahan CA, Seo EJ, and Yu BP. Dietary modulation of the progression of nephropathy in aging rats: an evaluation of the importance of protein. Am J Clin Nutr 49: 1217-1227, 1989.
19. McCarter RJ and Palmer J. Energy metabolism and aging: a lifelong study of Fischer 344 rats. Am J Physiol Endocrinol Metab 263: E448-E452, 1992.
20. McDonald RB, Florez-Duquet M, Murtagh-Mark C, and Horwitz BA. Relationship between cold-induced thermoregulation and spontaneous rapid body weight loss of aging F344 rats. Am J Physiol Regul Integr Comp Physiol 271: R1115-R1122, 1996.
21. McDonald RB, Hoban-Higgins TM, Ruhe RC, Fuller CA, and Horwitz BA. Alterations in endogenous circadian rhythm of core temperature in senescent Fischer 344 rats. Am J Physiol Regul Integr Comp Physiol 276: R824-R830, 1999.
22. Morley JE. Neuropeptide regulation of appetite and weight. Endocr Rev 8: 256-287. 1987.
23. Sarkisian CA and Lachs MS. "Failure to thrive" in older adults. Ann Intern Med 124: 1072-1078, 1996.
24. Shimokawa I, Higami Y, Hubbard GB, McMahan CA, Masoro EJ, and Yu BP. Diet and the suitability of the male Fischer 344 rat as a model for aging research. J Gerontol 48: B27-B32, 1993.
25. Silver AJ, Flood J, and Morley JE. Effect of gastrointestinal peptides on ingestion in young and old mice. Peptides 9: 221-226, 1988.
26. Snedecor GW and Cochran WG. Statistical Methods. Ames, IA: Iowa State University Press, 1967.
27. Turturro A, Witt WW, Lewis S, Hass BS, Lipman RD, and Hart RW. Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program. J Gerontol A Biol Sci Med Sci 54: B492-B501, 1999.
28. Wallace JI and Schwartz RS. Involuntary weight loss in elderly outpatients. Clin Geriatr Med 13: 717-735, 1997.
29. Winer BJ. Statistical Principles in Experimental Design. New York: McGraw-Hill, 1971.
30. Wolden-Hanson T, Mitton DR, McCants RL, Yellon SM, Wilkinson CW, Matsumoto AM, and Rasmussen DD. Daily melatonin administration to middle-aged male rats suppresses body weight, intra-abdominal adiposity, and plasma leptin and insulin independent of food intake and total body fat. Endocrinology 141: 487-497, 2000.
31. Yeh SS and Schuster MW. Geriatric cachexia: the role of cytokines. Am J Clin Nutr 70: 183-197, 1999.
32. Yu BP, Masoro EJ, and McMahan CA. Nutritional influences on aging of Fischer 344 rats. I. Physical, metabolic, and longevity characteristics. J Gerontol 40: 657-670, 1985.
33. Yu BP, Masoro EJ, Murata I, Bertrand HA, and Lynd FT. Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: longevity, growth, lean body mass, and disease. J Gerontol 37: 130-141, 1982.