Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo

Journal of Neuroscience Research

Volumn 84, Issue 8, 2006, Pages 1871-1878

  Madani, Rime ^a   Poirier, Raphael ^a   Wolfer, David P ^a   Welzl, Hans ^a   Groscurth, Peter ^a   Lipp, Hans Peter ^a   Lu, Bao ^b   El Mouedden, Mohammed ^c   Mercken, Marc ^c   Nitsch, Roger M ^a   Mohajeri, M Hasan ^a,d  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c CNS Pain and Alzheimer   (Belgium)

^d Division of Psychiatry Research   (Switzerland)

Author keywords

A clearance; Alzheimer's disease; Behavior; Neurodegeneration; Therapy

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; MEMBRANE METALLOENDOPEPTIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AVERSION; BEHAVIOR DISORDER; BRAIN CELL; CHEMICAL ANALYSIS; CLINICAL FEATURE; CONTROLLED STUDY; FOOD AVERSION; IN VIVO STUDY; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY;

AGE FACTORS; AMYLOID; ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BRAIN; CONDITIONING, OPERANT; ENZYME-LINKED IMMUNOSORBENT ASSAY; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; NEPRILYSIN; WATER DEPRIVATION;

EID: 33845450353     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21074     Document Type: Article

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