The functional γ-secretase inhibitor prevents production of amyloid β 1-34 in human and murine cell lines

Neuroscience Letters

Volumn 315, Issue 3, 2001, Pages 145-148

  Vandermeeren, Marc ^a   Geraerts, Martine ^a   Pype, Stefan ^a   Dillen, Lieve ^a   Van Hove, Carl ^a   Mercken, Marc ^a  

^a JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

secretase; Alzheimer's disease; Amyloid; Amyloid peptides; BACE 1; Mass spectrometry

Indexed keywords

AMYLOID BETA PROTEIN; ASPARAGINE; BETA SECRETASE; BRAIN PROTEIN; ENZYME INHIBITOR; GAMMA SECRETASE INHIBITOR; GLUTAMINE; LEUCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; INCUBATION TIME; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CELL LINE; CULTURE MEDIA; ENDOPEPTIDASES; ENZYME INHIBITORS; HUMANS; MICE; PEPTIDE FRAGMENTS; PROTEIN ISOFORMS; SOLUBILITY; TRANSFECTION;

EID: 0035960535     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)02369-2     Document Type: Article

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