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Volumn 14, Issue 6, 2005, Pages 333-349

Etiology and pathogenesis of the metabolic syndrome;Ätiologie und pathogenese des metabolischen syndroms

Author keywords

Dyslipidemia; Insulin resistance; Metabolic syndrome; Type 2 diabetes mellitus; Visceral obesity

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 33751583974     PISSN: 09420037     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (3)

References (129)
  • 2
    • 33747525791 scopus 로고    scopus 로고
    • Das metabolische syndrom: Wurzeln, mythen und fakten
    • Hanefeld M, Leonhardt W (ed). Gustav Fischer Verlag, Jena Stuttgart
    • Hanefeld M: Das Metabolische Syndrom: Wurzeln, Mythen und Fakten. In: Hanefeld M, Leonhardt W (ed): Das Metabolische Syndrom. Gustav Fischer Verlag, Jena Stuttgart (1996) 15-26
    • (1996) Das Metabolische Syndrom , pp. 15-26
    • Hanefeld, M.1
  • 4
    • 0000730344 scopus 로고    scopus 로고
    • Executive summary. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Heart, Lung and Blood Institute, 2001 May. 28. Third report of the National Cholesterol Education Program (NCEP)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Executive summary. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Heart, Lung and Blood Institute, 2001 May. 28. Third report of the National Cholesterol Education Program (NCEP). JAMA 285 (2001) 2486-97
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 6
    • 84910110212 scopus 로고    scopus 로고
    • The insulin resistance syndrome: Impact on lipoprotein metabolism and atherothrombosis
    • Ginsberg H N, Huang L S: The insulin resistance syndrome: impact on lipoprotein metabolism and atherothrombosis. J Cardiovasc Risk 7 (2000) 325-331
    • (2000) J Cardiovasc Risk , vol.7 , pp. 325-331
    • Ginsberg, H.N.1    Huang, L.S.2
  • 7
    • 0042178310 scopus 로고    scopus 로고
    • Influence of plasma free fatty acids on lipoprotein synthesis and diabetic dyslipidemia
    • Julius U: influence of plasma free fatty acids on lipoprotein synthesis and diabetic dyslipidemia. Exp Clin Endocrinol Diabetes 111 (2003) 246-250
    • (2003) Exp Clin Endocrinol Diabetes , vol.111 , pp. 246-250
    • Julius, U.1
  • 8
    • 0032787481 scopus 로고    scopus 로고
    • Very low density lipoprotein overproduction is maximally expressed in early insulin resistant states
    • Pietzsch J, Julius U, Kirch C, Fischer S, Hanefeld M: Very low density lipoprotein overproduction is maximally expressed in early insulin resistant states. Ann NY Acad Sci 892 (1999) 319-322
    • (1999) Ann NY Acad Sci , vol.892 , pp. 319-322
    • Pietzsch, J.1    Julius, U.2    Kirch, C.3    Fischer, S.4    Hanefeld, M.5
  • 9
    • 0042122304 scopus 로고    scopus 로고
    • A paradox resolved: The postprandial model of insulin resistance explains why gynoid adiposity appears to be protective
    • McCarty M F: A paradox resolved: the postprandial model of insulin resistance explains why gynoid adiposity appears to be protective. Med Hypotheses 61 (2003) 173-6
    • (2003) Med Hypotheses , vol.61 , pp. 173-176
    • McCarty, M.F.1
  • 12
    • 0002260213 scopus 로고
    • Obesity, insulin resistance and diabetes
    • Alberti KGM M, Krall L P (ed). Elsevier Science Publishers
    • Björntorp P: Obesity, insulin resistance and diabetes. In: Alberti KGM M, Krall L P (ed): The Diabetes Annual/6. Elsevier Science Publishers (1991) 347-370
    • (1991) The Diabetes Annual/6 , pp. 347-370
    • Björntorp, P.1
  • 13
    • 0842333077 scopus 로고    scopus 로고
    • The 1st world congress on the insulin resistance syndrome
    • Bloomgarden Z T: The 1st world congress on the insulin resistance syndrome. Diabetes Care 27 (2004) 602-609
    • (2004) Diabetes Care , vol.27 , pp. 602-609
    • Bloomgarden, Z.T.1
  • 15
    • 1842534924 scopus 로고    scopus 로고
    • Nutrient-induced insulin resistance in human skeletal muscle
    • Krebs M, Roden M: Nutrient-induced insulin resistance in human skeletal muscle. Curr Med Chem 11 (2004) 901-908
    • (2004) Curr Med Chem , vol.11 , pp. 901-908
    • Krebs, M.1    Roden, M.2
  • 17
    • 0036294713 scopus 로고    scopus 로고
    • SREBP-1: Gene regulatory key to syndrome X?
    • Muller-Wieland D, Kotzka J: SREBP-1: gene regulatory key to syndrome X?. Ann N Y Acad Sci 967 (2002) 19-27
    • (2002) Ann N Y Acad Sci , vol.967 , pp. 19-27
    • Muller-Wieland, D.1    Kotzka, J.2
  • 18
    • 4444320032 scopus 로고    scopus 로고
    • Features of the metabolic syndrome are associated with objectively measured physical activity and fitness in Danish children
    • Brage S, Wedderkopp N, Ekelund U, Franks P W, Wareham N J, Andersen L B, Froberg K: Features of the metabolic syndrome are associated with objectively measured physical activity and fitness in Danish children. Diabetes Care 27 (2004) 2141-48
    • (2004) Diabetes Care , vol.27 , pp. 2141-2148
    • Brage, S.1    Wedderkopp, N.2    Ekelund, U.3    Franks, P.W.4    Wareham, N.J.5    Andersen, L.B.6    Froberg, K.7
  • 19
    • 0036726374 scopus 로고    scopus 로고
    • Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome
    • Laaksonen D E, Lakka H M, Salonen J T, Niskanen L K, Rauramaa R, Lakka T A: Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome. Diabetes Care 25 (2002) 1612-18
    • (2002) Diabetes Care , vol.25 , pp. 1612-1618
    • Laaksonen, D.E.1    Lakka, H.M.2    Salonen, J.T.3    Niskanen, L.K.4    Rauramaa, R.5    Lakka, T.A.6
  • 20
    • 18144363180 scopus 로고    scopus 로고
    • Physical activity energy expenditure predicts progression toward the metabolic syndrome independently of aerobic fitness in middle-aged healthy Caucasians
    • Ekelund U, Brage S, Franks P W, Hennings S, Emms S, Wareham N J: Physical activity energy expenditure predicts progression toward the metabolic syndrome independently of aerobic fitness in middle-aged healthy Caucasians. Diabetes Care 28 (2005) 1195-1200
    • (2005) Diabetes Care , vol.28 , pp. 1195-1200
    • Ekelund, U.1    Brage, S.2    Franks, P.W.3    Hennings, S.4    Emms, S.5    Wareham, N.J.6
  • 22
    • 4644243396 scopus 로고    scopus 로고
    • Serum ferritin and risk of the metabolic syndrome in U.S. adults
    • Jehn M, Clark J M, Guallar E: Serum ferritin and risk of the metabolic syndrome in U.S. adults. Diabetes Care 27 (2004) 2422-8
    • (2004) Diabetes Care , vol.27 , pp. 2422-2428
    • Jehn, M.1    Clark, J.M.2    Guallar, E.3
  • 23
    • 1442348814 scopus 로고    scopus 로고
    • Insulin resistance and cardiovascular disease risk factors in children of parents with the insulin resistance (metabolic) syndrome
    • Pankow J S, Jacobs D R, Steinberger J, Moran A, Sinaiko A R: Insulin resistance and cardiovascular disease risk factors in children of parents with the insulin resistance (metabolic) syndrome. Diabetes Care 27 (2004) 775-780
    • (2004) Diabetes Care , vol.27 , pp. 775-780
    • Pankow, J.S.1    Jacobs, D.R.2    Steinberger, J.3    Moran, A.4    Sinaiko, A.R.5
  • 24
    • 14644415925 scopus 로고    scopus 로고
    • A prospective study on the prevalence of metabolic syndrome among healthy french families: Two cardiovascular risk factors (HDL cholesterol and tumor necrosis factor-alpha) are revealed in the offspring of parents with metabolic syndrome
    • Maumus S, Marie B, Siest G, Visvikis-Siest S: A prospective study on the prevalence of metabolic syndrome among healthy french families: two cardiovascular risk factors (HDL cholesterol and tumor necrosis factor-alpha) are revealed in the offspring of parents with metabolic syndrome. Diabetes Care 28 (2005) 675-82
    • (2005) Diabetes Care , vol.28 , pp. 675-682
    • Maumus, S.1    Marie, B.2    Siest, G.3    Visvikis-Siest, S.4
  • 28
    • 0036303247 scopus 로고    scopus 로고
    • The effects of the Pro12Ala polymorphism of the peroxisome prolife-ratror-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth
    • Eriksson J, Lindi V, Uusitupa M, Forsen. TJ, Laakso M, Osmond C, Barker D: The effects of the Pro12Ala polymorphism of the peroxisome prolife-ratror-activated receptor-gamma2 gene on insulin sensitivity and insulin metabolism interact with size at birth. Diabetes 51 (2002) 2321-2324
    • (2002) Diabetes , vol.51 , pp. 2321-2324
    • Eriksson, J.1    Lindi, V.2    Uusitupa, M.3    Forsen, T.J.4    Laakso, M.5    Osmond, C.6    Barker, D.7
  • 29
    • 0038327855 scopus 로고    scopus 로고
    • Metabolic syndrome; multiple candidate genes, multiple environmental factors: Multiple syndromes?
    • Nestel P J: Metabolic syndrome; multiple candidate genes, multiple environmental factors: multiple syndromes?. Int J Clin Practice 134 (Suppl) (2003) 3-9
    • (2003) Int J Clin Practice , vol.134 , Issue.SUPPL. , pp. 3-9
    • Nestel, P.J.1
  • 30
  • 31
    • 9444285816 scopus 로고    scopus 로고
    • Dylipidemia and the metabolic syndrome
    • Bloomgarden Z T: Dylipidemia and the metabolic syndrome. Diabetes Care 27 (2004) 3009-16
    • (2004) Diabetes Care , vol.27 , pp. 3009-3016
    • Bloomgarden, Z.T.1
  • 32
    • 0037219294 scopus 로고    scopus 로고
    • The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to infra-abdominal fat
    • Nieves D J, Cnop M, Retzlaff B, Walden C E, Brunzell J D, Knopp R H, Kahn S E: The atherogenic lipoprotein profile associated with obesity and insulin resistance is largely attributable to infra-abdominal fat. Diabetes 52 (2003) 172-79
    • (2003) Diabetes , vol.52 , pp. 172-179
    • Nieves, D.J.1    Cnop, M.2    Retzlaff, B.3    Walden, C.E.4    Brunzell, J.D.5    Knopp, R.H.6    Kahn, S.E.7
  • 33
    • 1842558695 scopus 로고    scopus 로고
    • Associations between the fatty acid content of triglyceride, visceral adipose tissue accumulation, and components of the insulin resistance syndrome
    • Tremblay A J, Despres J P, Piche M E, Nadeau A, Bergeron J, Almeras N, Tremblay A, Lemieux S: Associations between the fatty acid content of triglyceride, visceral adipose tissue accumulation, and components of the insulin resistance syndrome. Metabolism 53 (2004) 310-317
    • (2004) Metabolism , vol.53 , pp. 310-317
    • Tremblay, A.J.1    Despres, J.P.2    Piche, M.E.3    Nadeau, A.4    Bergeron, J.5    Almeras, N.6    Tremblay, A.7    Lemieux, S.8
  • 34
    • 0023695231 scopus 로고
    • Abdominal obesity and the development of non-insulin-dependent diabetes mellitus
    • Björntorp P: Abdominal obesity and the development of non-insulin-dependent diabetes mellitus. Diabetes Metab Rev 4 (1988) 615-622
    • (1988) Diabetes Metab Rev , vol.4 , pp. 615-622
    • Björntorp, P.1
  • 35
    • 1642415851 scopus 로고    scopus 로고
    • Waist circumference and not body mass index explains obesity-related health risk
    • Janssen I, Katzmarzyk P T, Ross R: Waist circumference and not body mass index explains obesity-related health risk. Am J Clin Nutr 79 (2004) 347-349
    • (2004) Am J Clin Nutr , vol.79 , pp. 347-349
    • Janssen, I.1    Katzmarzyk, P.T.2    Ross, R.3
  • 37
    • 7444240186 scopus 로고    scopus 로고
    • Risk factores for the metabolic syndrome - The Coronary Artery Risk Development in Young Adults (CARDIA) study, 1985-2001
    • Carnethon M R, Loria C M, Hill J O, Sidney S, Savage PJ, Liu K: Risk factores for the metabolic syndrome - The Coronary Artery Risk Development in Young Adults (CARDIA) study, 1985-2001. Diabetes Care 27 (2004) 2707-15
    • (2004) Diabetes Care , vol.27 , pp. 2707-2715
    • Carnethon, M.R.1    Loria, C.M.2    Hill, J.O.3    Sidney, S.4    Savage, P.J.5    Liu, K.6
  • 38
    • 9444263082 scopus 로고    scopus 로고
    • Alcohol consumption and the prevalence of the metabolic syndrome in the U.S. - A cross-sectional analysis of dat from the Third National Health and Nutrition Examination Survey
    • Freiberg M S, Cabral H J, Heeren T C, Vasan R S, Ellison R C: Alcohol consumption and the prevalence of the metabolic syndrome in the U.S. - A cross-sectional analysis of dat from the Third National Health and Nutrition Examination Survey. Diabetes Care 27 (2004) 2954-59
    • (2004) Diabetes Care , vol.27 , pp. 2954-2959
    • Freiberg, M.S.1    Cabral, H.J.2    Heeren, T.C.3    Vasan, R.S.4    Ellison, R.C.5
  • 39
    • 7444253874 scopus 로고    scopus 로고
    • Glycemic index and dietary fiber and the risk of type 2 diabetes
    • Hodge A M, English D R, O'Dea K, Giles G G: Glycemic index and dietary fiber and the risk of type 2 diabetes. Diabetes Care 27 (2004) 2701-6
    • (2004) Diabetes Care , vol.27 , pp. 2701-2706
    • Hodge, A.M.1    English, D.R.2    O'Dea, K.3    Giles, G.G.4
  • 40
    • 0042665536 scopus 로고    scopus 로고
    • Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study
    • Sattar N, Gaw A, Scherbakova O, Ford I, O'Reilly D, Haffner S, Isles C, Macfarlane P, Packard C, Cobbe S, Shepherd: Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation 108 (2003) 414-419
    • (2003) Circulation , vol.108 , pp. 414-419
    • Sattar, N.1    Gaw, A.2    Scherbakova, O.3    Ford, I.4    O'Reilly, D.5    Haffner, S.6    Isles, C.7    Macfarlane, P.8    Packard, C.9    Cobbe, S.10    Shepherd11
  • 43
    • 4444376099 scopus 로고    scopus 로고
    • Cardiovascular disease risk factors predict the development of type 2 diabetes: The insulin resistance atherosclerosis study
    • D'Agostino Jr. R B, Hamman R F, Karter A J, Mykkanen L, Wagenknecht L E, Haffner S M: Cardiovascular disease risk factors predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes Care 27 (2004) 2234-40
    • (2004) Diabetes Care , vol.27 , pp. 2234-2240
    • D'Agostino Jr., R.B.1    Hamman, R.F.2    Karter, A.J.3    Mykkanen, L.4    Wagenknecht, L.E.5    Haffner, S.M.6
  • 44
    • 2942517498 scopus 로고    scopus 로고
    • Increased levels of triglycerides, BMI and blood pressure and low physical activity increase the risk of diabetes in Swedish women. A prospective 18-year follow-up of the BEDA study
    • Dotevall A, Johansson S, Wilhelmsen L, Rosengren A: Increased levels of triglycerides, BMI and blood pressure and low physical activity increase the risk of diabetes in Swedish women. A prospective 18-year follow-up of the BEDA study. Diabet Med 21 (2004) 615-22
    • (2004) Diabet Med , vol.21 , pp. 615-622
    • Dotevall, A.1    Johansson, S.2    Wilhelmsen, L.3    Rosengren, A.4
  • 45
    • 0242300702 scopus 로고    scopus 로고
    • The metabolic syndrome as predictor of type 2 diabetes - The San Antonio Heart Study
    • Lorenzo C, Okoloise M, Williams K, Stern M P, Haffner S M: The metabolic syndrome as predictor of type 2 diabetes - The San Antonio Heart Study. Diabetes Care 26 (2003) 3153-59
    • (2003) Diabetes Care , vol.26 , pp. 3153-3159
    • Lorenzo, C.1    Okoloise, M.2    Williams, K.3    Stern, M.P.4    Haffner, S.M.5
  • 46
    • 7444269499 scopus 로고    scopus 로고
    • Does the metabolic syndrome improve identification of individuals at risk of type 2 diabetes and/or cardiovascular disease?
    • Stern M P, Williams K, González-Villalpando C, Hunt K J, Haffner S M: Does the metabolic syndrome improve identification of individuals at risk of type 2 diabetes and/or cardiovascular disease?. Diabetes Care 27 (2004) 2676-81
    • (2004) Diabetes Care , vol.2 , Issue.27 , pp. 2676-2681
    • Stern, M.P.1    Williams, K.2    González-Villalpando, C.3    Hunt, K.J.4    Haffner, S.M.5
  • 48
    • 0032786131 scopus 로고    scopus 로고
    • Metabolic basis of low high density lipoprotein in subjects with impaired glucose tolerance
    • Pietzsch J, Julius U, Hanefeld M: Metabolic basis of low high density lipoprotein in subjects with impaired glucose tolerance. Ann NY Acad Sci 892 (1999) 323-326
    • (1999) Ann NY Acad Sci , vol.892 , pp. 323-326
    • Pietzsch, J.1    Julius, U.2    Hanefeld, M.3
  • 49
    • 84860056029 scopus 로고    scopus 로고
    • Intravasaler lipidtransfer bei gestörter glukosetoleranz (IGT): Beitrag zur rolle des cholesteroiester-transferproteins (CETP)
    • Heinle H, Schulte H, Hahmann H (ed). Deutsche Gesellschaft für Arterioskleroseforschung, Tübingen
    • Julius U, Kirschner E, Pietzsch J: Intravasaler Lipidtransfer bei gestörter Glukosetoleranz (IGT): Beitrag zur Rolle des Cholesteroiester- Transferproteins (CETP). In: Heinle H, Schulte H, Hahmann H (ed): Besondere Aspekte der cerebrovaskulären und peripheren Arteriosklerose. Deutsche Gesellschaft für Arterioskleroseforschung, Tübingen (2004) 50-54
    • (2004) Besondere Aspekte der Cerebrovaskulären und Peripheren Arteriosklerose , pp. 50-54
    • Julius, U.1    Kirschner, E.2    Pietzsch, J.3
  • 50
    • 1842527452 scopus 로고    scopus 로고
    • The metabolic syndrome, circulating oxidized LDL, and risk of myocardial infarction in well-functioning elderly people in the health, aging, and body composition cohort
    • Holvoet P, Kritchevsky S B, Tracy R P, Mertens A, Rubin S M, Butler J, Goodpaster B, Harris T B: The metabolic syndrome, circulating oxidized LDL, and risk of myocardial infarction in well-functioning elderly people in the health, aging, and body composition cohort. Diabetes 53 (2004) 1068-1073
    • (2004) Diabetes , vol.53 , pp. 1068-1073
    • Holvoet, P.1    Kritchevsky, S.B.2    Tracy, R.P.3    Mertens, A.4    Rubin, S.M.5    Butler, J.6    Goodpaster, B.7    Harris, T.B.8
  • 51
    • 4944232643 scopus 로고    scopus 로고
    • Oxidized LDL and coronary heart disease
    • Holvoet P: Oxidized LDL and coronary heart disease. Acta Cardiol 59 (2004) 479-84
    • (2004) Acta Cardiol , vol.59 , pp. 479-484
    • Holvoet, P.1
  • 53
    • 0037407403 scopus 로고    scopus 로고
    • NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Third National Health and Nutrition Examination Survey (NHANES III); National Cholesterol Education Program (NCEP)
    • Alexander C M, Landsman P B, Teutsch S M, Haffner S M: NCEP-defined metabolic syndrome, diabetes, and prevalence of coronary heart disease among NHANES III participants age 50 years and older. Third National Health and Nutrition Examination Survey (NHANES III); National Cholesterol Education Program (NCEP). Diabetes 52 (2003) 1210-14
    • (2003) Diabetes , vol.52 , pp. 1210-1214
    • Alexander, C.M.1    Landsman, P.B.2    Teutsch, S.M.3    Haffner, S.M.4
  • 54
    • 14644425258 scopus 로고    scopus 로고
    • Cardiovascular disease in U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive protein
    • Malik S, Wong N D, Franklin S, Pio J, Fairchild C, Chen R: Cardiovascular disease in U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive protein. Diabetes Care 28 (2005) 690-3
    • (2005) Diabetes Care , vol.28 , pp. 690-693
    • Malik, S.1    Wong, N.D.2    Franklin, S.3    Pio, J.4    Fairchild, C.5    Chen, R.6
  • 56
    • 1442275321 scopus 로고    scopus 로고
    • Insulin sensitivity, insulinemia, and coronary artery disease - The Insulin Resistance Atherosclerosis Study
    • for the Insulin Resistance Atherosclerosis Study Investigators
    • Rewers M, Zaccaro D, D'Agostino R, Haffner S, Saad M F, Selby J V, Bergman R, Savage P, for the Insulin Resistance Atherosclerosis Study Investigators: Insulin sensitivity, insulinemia, and coronary artery disease - The Insulin Resistance Atherosclerosis Study. Diabetes Care 27 (2004) 781-787
    • (2004) Diabetes Care , vol.27 , pp. 781-787
    • Rewers, M.1    Zaccaro, D.2    D'Agostino, R.3    Haffner, S.4    Saad, M.F.5    Selby, J.V.6    Bergman, R.7    Savage, P.8
  • 57
    • 0347716449 scopus 로고    scopus 로고
    • Association of the Metabolic Syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey
    • Ninomiya J K, L'Italien G, Criqui M, Whyte J, Gamst A, Chen R: Association of the Metabolic Syndrome with history of myocardial infarction and stroke in the Third National Health and Nutrition Examination Survey. Circulation 109 (2004) 42-46
    • (2004) Circulation , vol.109 , pp. 42-46
    • Ninomiya, J.K.1    L'Italien, G.2    Criqui, M.3    Whyte, J.4    Gamst, A.5    Chen, R.6
  • 59
  • 60
    • 1242291791 scopus 로고    scopus 로고
    • Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: A report rom the Women's Ischemia Syndrome Evaluation (WISE) study
    • Kip K E, Marroquin O C, Kelley D E, Johnson B D, Kelsey S F, Shaw L J, Rogers W J, Reis S E: Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report rom the Women's Ischemia Syndrome Evaluation (WISE) study. Circulation 109 (2004) 706-13
    • (2004) Circulation , vol.109 , pp. 706-713
    • Kip, K.E.1    Marroquin, O.C.2    Kelley, D.E.3    Johnson, B.D.4    Kelsey, S.F.5    Shaw, L.J.6    Rogers, W.J.7    Reis, S.E.8
  • 63
    • 0036838542 scopus 로고    scopus 로고
    • Leukocyte count and fibrinogen are associated with carotid and femoral intima-media thickness in a risk population for diabetes
    • Temelkova-Kurktschiev T, Koehler C, Henkel I, Hanefeld M: Leukocyte count and fibrinogen are associated with carotid and femoral intima-media thickness in a risk population for diabetes. Cardiorasc Res 56 (2002) 277-83
    • (2002) Cardiorasc Res , vol.56 , pp. 277-283
    • Temelkova-Kurktschiev, T.1    Koehler, C.2    Henkel, I.3    Hanefeld, M.4
  • 66
    • 0037834899 scopus 로고    scopus 로고
    • The metabolic syndrome and C-reactive protein, fibrinogen, and leukocyte count: Findings from the Third National Health and Nutrition Examination Survey
    • Ford ES: The metabolic syndrome and C-reactive protein, fibrinogen, and leukocyte count: findings from the Third National Health and Nutrition Examination Survey. Atherosclerosis 168 (2003) 351-8
    • (2003) Atherosclerosis , vol.168 , pp. 351-358
    • Ford, E.S.1
  • 67
    • 9444246403 scopus 로고    scopus 로고
    • Association between inflammation and insulin resistance in U.S. nondiabetic adults - Results from the Third National Health and Nutrition Examination Survey
    • Chen J, Wildman R P, Hamm L L, Muntner P, Reynolds K, Whelton P K, He J: Association between inflammation and insulin resistance in U.S. nondiabetic adults - Results from the Third National Health and Nutrition Examination Survey. Diabetes Care 27 (2004) 2960-68
    • (2004) Diabetes Care , vol.27 , pp. 2960-2968
    • Chen, J.1    Wildman, R.P.2    Hamm, L.L.3    Muntner, P.4    Reynolds, K.5    Whelton, P.K.6    He, J.7
  • 68
    • 0038691972 scopus 로고    scopus 로고
    • Atherosclerosis Risk in Communities Study. Low-grade systemic inflammation and the development of type 2 diabetes: The atherosclerosis risk in communities study
    • Atherosclerosis Risk in Communities Study
    • Duncan B B, Schmidt M I, Pankow J S, Ballanryne C, Couper D, Vigo A, Hoogeveen R, Folsom A, Heiss G, Atherosclerosis Risk in Communities Study: Atherosclerosis Risk in Communities Study. Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes 52 (2003) 1799-1805
    • (2003) Diabetes , vol.52 , pp. 1799-1805
    • Duncan, B.B.1    Schmidt, M.I.2    Pankow, J.S.3    Ballanryne, C.4    Couper, D.5    Vigo, A.6    Hoogeveen, R.7    Folsom, A.8    Heiss, G.9
  • 69
    • 0036278738 scopus 로고    scopus 로고
    • Subclinical inflammation is strongly related to insulin resistance but not to impaired insulin secretion in a high risk population for diabetes
    • Temelkova-Kurktschiev T, Siegert G, Bergmann S, Henkel K, Kochler C, Jaross W, Hanefeld M: Subclinical inflammation is strongly related to insulin resistance but not to impaired insulin secretion in a high risk population for diabetes. Metabolism 51 (2002) 743-9.
    • (2002) Metabolism , vol.51 , pp. 743-749
    • Temelkova-Kurktschiev, T.1    Siegert, G.2    Bergmann, S.3    Henkel, K.4    Kochler, C.5    Jaross, W.6    Hanefeld, M.7
  • 70
    • 0034704893 scopus 로고    scopus 로고
    • C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker P M, Hennekens C H, Buring J E. Rifai N: C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342 (2000) 836-42
    • (2000) N Engl J Med , vol.342 , pp. 836-842
    • Ridker, P.M.1    Hennekens, C.H.2    Buring, J.E.3    Rifai, N.4
  • 71
    • 1442301080 scopus 로고    scopus 로고
    • Inflammatory markers and risk of developing type 2 diabetes in women
    • Hu F B, Meigs J B, Li T Y, Ritai N, Manson J E: Inflammatory markers and risk of developing type 2 diabetes in women. Diabetes 53 (2004) 693-700
    • (2004) Diabetes , vol.53 , pp. 693-700
    • Hu, F.B.1    Meigs, J.B.2    Li, T.Y.3    Ritai, N.4    Manson, J.E.5
  • 72
    • 0042594649 scopus 로고    scopus 로고
    • C-reactive protein and glycemic control in adults with diabetes
    • King D E, Mainous A G 3, Thomas A, Pearson W: C-reactive protein and glycemic control in adults with diabetes. Diabetes Care 26 (2003) 1535-2539
    • (2003) Diabetes Care , vol.26 , pp. 1535-2539
    • King, D.E.1    Mainous III, A.G.2    Thomas, A.3    Pearson, W.4
  • 79
    • 2942698938 scopus 로고    scopus 로고
    • A novel pathway to rhe manifestations of metabolic syndrome
    • Sonnenberg G E, Krakower G R, Kissebah A H A novel pathway to rhe manifestations of metabolic syndrome. Obes Res 12 (2004) 180-186
    • (2004) Obes Res , vol.12 , pp. 180-186
    • Sonnenberg, G.E.1    Krakower, G.R.2    Kissebah, A.H.3
  • 83
    • 0030680265 scopus 로고    scopus 로고
    • Insulin resistance, hyperinsulinemia, and blood pressure: Role of age and obesity: European Group for the Study of Insulin Resistance (EGIR)
    • Ferrannini E, Natali A, Capaldo B, Lehtovirta M, Jacob S, Yki-Jarvinen H: Insulin resistance, hyperinsulinemia, and blood pressure: role of age and obesity: European Group for the Study of Insulin Resistance (EGIR). Hypertension 30 (1997) 1144-1149
    • (1997) Hypertension , vol.30 , pp. 1144-1149
    • Ferrannini, E.1    Natali, A.2    Capaldo, B.3    Lehtovirta, M.4    Jacob, S.5    Yki-Jarvinen, H.6
  • 84
    • 0026021161 scopus 로고
    • Insulin resistance: A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease
    • DeFronzo R A, Ferrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diabetes Care 14 (1991) 173-194
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.A.1    Ferrannini, E.2
  • 87
    • 3042528755 scopus 로고    scopus 로고
    • Is there a rationale for angiotensin blockade in the management of obesity hypertension?
    • Sharma A M: Is there a rationale for angiotensin blockade in the management of obesity hypertension?. Hypertension 44 (2004) 12-9
    • (2004) Hypertension , vol.44 , pp. 12-19
    • Sharma, A.M.1
  • 88
    • 11244311897 scopus 로고    scopus 로고
    • Fat cells may be the obesity-hypertension link: Human adipogenic factors stimulate aldosterone secretion from adrenocortical cells
    • Ehrhart-Bornstein M, Arakelyan K, Krug A W, Scherbaum W A, Bornstein S R: Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. Endocr Res 30 (2004) 865-70
    • (2004) Endocr Res , vol.30 , pp. 865-870
    • Ehrhart-Bornstein, M.1    Arakelyan, K.2    Krug, A.W.3    Scherbaum, W.A.4    Bornstein, S.R.5
  • 89
    • 0014393929 scopus 로고
    • Bedeutung der hypertonie in der pathogenese des diabetes mellitus
    • Dieterle P, Bottermann P, Schwarz K: Bedeutung der Hypertonie in der Pathogenese des Diabetes mellitus. Verh Dtsch Ges Inn Med 74 (1968) 434-7
    • (1968) Verh Dtsch Ges Inn Med , vol.74 , pp. 434-437
    • Dieterle, P.1    Bottermann, P.2    Schwarz, K.3
  • 90
    • 0043166523 scopus 로고    scopus 로고
    • Relationship of metabolic syndrome and fibrinolytic dysfunction to cardiovascular disease
    • Study of Health Assessment and Risk in Ethnic Groups, Study of Health Assessment and Risk Evaluation in Aboriginal Peoples Investigators
    • Anand S S, Yi Q, Gerstein H, Lonn E, Jacobs R, Vuksan V, Teo K, Davis B, Montague P, Yusuf S, Study of Health Assessment and Risk in Ethnic Groups, Study of Health Assessment and Risk Evaluation in Aboriginal Peoples Investigators: Relationship of metabolic syndrome and fibrinolytic dysfunction to cardiovascular disease. Circulation 108 (2003) 420-425
    • (2003) Circulation , vol.108 , pp. 420-425
    • Anand, S.S.1    Yi, Q.2    Gerstein, H.3    Lonn, E.4    Jacobs, R.5    Vuksan, V.6    Teo, K.7    Davis, B.8    Montague, P.9    Yusuf, S.10
  • 91
    • 0035038163 scopus 로고    scopus 로고
    • Obesity is independently associated with coronary endothelial dysfunction in patients with normal or mildly diseased coronary arteries
    • Al Suwaidi J, Higano S, Holmes D J, Lennon R, Lerman A: Obesity is independently associated with coronary endothelial dysfunction in patients with normal or mildly diseased coronary arteries. J Am Coll Cardiol 37 (2001) 1523-1528
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1523-1528
    • Al Suwaidi, J.1    Higano, S.2    Holmes, D.J.3    Lennon, R.4    Lerman, A.5
  • 92
    • 0029977757 scopus 로고    scopus 로고
    • Obesity/insulin resistance is associated with endothelial dysfunction: Implications for the syndrome of insulin resistance
    • Steinberg H O, Chaker H, Learning R, Johnson A, Brechtel G, Baron A D: Obesity/insulin resistance is associated with endothelial dysfunction: implications for the syndrome of insulin resistance. J Clin Invest 97 (1996) 2601-2610
    • (1996) J Clin Invest , vol.97 , pp. 2601-2610
    • Steinberg, H.O.1    Chaker, H.2    Learning, R.3    Johnson, A.4    Brechtel, G.5    Baron, A.D.6
  • 96
    • 17844363297 scopus 로고    scopus 로고
    • The contribution of viscera adipose tissue to splanchnic cortisol production in healthy humans
    • Andrew R, Westerbacka J, Wahren J, Yki-Järvinen H, Walker B R: The contribution of viscera adipose tissue to splanchnic cortisol production in healthy humans. Diabetes 54 (2005) 1364-1370
    • (2005) Diabetes , vol.54 , pp. 1364-1370
    • Andrew, R.1    Westerbacka, J.2    Wahren, J.3    Yki-Järvinen, H.4    Walker, B.R.5
  • 101
    • 1842538111 scopus 로고    scopus 로고
    • Association of bioavailable, free, and total testosterone with insulin resistance: Influence of sex hormone-binding globulin and body fat
    • Tsai E C, Matsumoto A M, Fujimoto W Y, Boyko E J: Association of bioavailable, free, and total testosterone with insulin resistance: influence of sex hormone-binding globulin and body fat. Diabetes Care 27 (2004) 861-8
    • (2004) Diabetes Care , vol.27 , pp. 861-868
    • Tsai, E.C.1    Matsumoto, A.M.2    Fujimoto, W.Y.3    Boyko, E.J.4
  • 103
    • 1842479594 scopus 로고    scopus 로고
    • Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women
    • Lee C C, Kasa-Vubu J Z, Supiano M A: Androgenicity and obesity are independently associated with insulin sensitivity in postmenopausal women. Metabolism 53 (2004) 507-12
    • (2004) Metabolism , vol.53 , pp. 507-512
    • Lee, C.C.1    Kasa-Vubu, J.Z.2    Supiano, M.A.3
  • 104
    • 0038021584 scopus 로고    scopus 로고
    • Association of endogenous sex hormones and insulin resistance among postmenopausal women: Results from the Postmenopausal Estrogen/Progestin Intervention Trial
    • Kalish G M, Barrert-Connor E, Laughlin G A, Gulanski B I: Association of endogenous sex hormones and insulin resistance among postmenopausal women: results from the Postmenopausal Estrogen/Progestin Intervention Trial. J Clin Endocrinol Metab 88 (2003) 1646-52
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1646-1652
    • Kalish, G.M.1    Barrert-Connor, E.2    Laughlin, G.A.3    Gulanski, B.I.4
  • 105
    • 4544388002 scopus 로고    scopus 로고
    • Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: The atherosclerosis risk in communities study
    • Golden S H, Ding J, Szklo M, Schmidt M I, Duncan B B, Dobs A: Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities study. Am J Epidemiol 160 (2004) 540-8
    • (2004) Am J Epidemiol , vol.160 , pp. 540-548
    • Golden, S.H.1    Ding, J.2    Szklo, M.3    Schmidt, M.I.4    Duncan, B.B.5    Dobs, A.6
  • 106
    • 17844367331 scopus 로고    scopus 로고
    • Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome
    • Apridonidze T, Essah P A, Iuorno M J, Nestler J E: Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome. J Clin Endocrinol Metab 90 (2005) 1929-35
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1929-1935
    • Apridonidze, T.1    Essah, P.A.2    Iuorno, M.J.3    Nestler, J.E.4
  • 107
    • 0027971625 scopus 로고
    • Evidence for a defect in insulin metabolism in hyperandrogenic women with polycystic ovarian syndrome
    • Buffington C K, Kitabchi A E: Evidence for a defect in insulin metabolism in hyperandrogenic women with polycystic ovarian syndrome. Metabolism 43 (1994) 1367-72.
    • (1994) Metabolism , vol.43 , pp. 1367-1372
    • Buffington, C.K.1    Kitabchi, A.E.2
  • 108
    • 84860048266 scopus 로고    scopus 로고
    • Gestörte hàmostase bei diabetes mellitus und metabolischem syndrom: Einfluβ faktoren und potentielle therapieinterventionen
    • Hanefeld M, Leonhardt W (ed). Gustav Fischer Verlag, Jena Stuttgart
    • Schernthaner G: Gestörte Hàmostase bei Diabetes mellitus und Metabolischem Syndrom: Einfluβ faktoren und potentielle Therapieinterventionen. In: Hanefeld M, Leonhardt W (ed): Das Metabolische Syndrom - ein integriertes Konzept zur Diagnostik und Therapie eines Clusters von Zivilisationskrankheiten. Gustav Fischer Verlag, Jena Stuttgart (1996) 138-161
    • (1996) Das Metabolische Syndrom - Ein Integriertes Konzept zur Diagnostik und Therapie Eines Clusters von Zivilisationskrankheiten , pp. 138-161
    • Schernthaner, G.1
  • 109
    • 20444388705 scopus 로고    scopus 로고
    • The metabolic syndrome and insulin resistance: Relationship to haemostatic and inflammatory markers in older nondiabetic men
    • Wannamethee S G, Lowe GDO, Shaper A G, Rumlev A, Lennon L, Whincup P H: The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older nondiabetic men. Atherosclerosis 181 (2005) 101-8
    • (2005) Atherosclerosis , vol.181 , pp. 101-108
    • Wannamethee, S.G.1    Lowe, G.D.O.2    Shaper, A.G.3    Rumlev, A.4    Lennon, L.5    Whincup, P.H.6
  • 110
    • 12244256099 scopus 로고    scopus 로고
    • Hemostatic risk factors and insulin sensitivity, regional body fat distribution, and the metabolic syndrome
    • Godsland I F, Crook D, Proudler A J, Stevenson J C: Hemostatic risk factors and insulin sensitivity, regional body fat distribution, and the metabolic syndrome. J Clin Endocrinol Metab 90 (2005) 190-7
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 190-197
    • Godsland, I.F.1    Crook, D.2    Proudler, A.J.3    Stevenson, J.C.4
  • 111
    • 8844247151 scopus 로고    scopus 로고
    • The plasminogen activator system in young and lean women with polycystic ovary syndrome
    • Tarkun I, Canturk Z, Arslan B C, Turernen E, Tarkun P: The plasminogen activator system in young and lean women with polycystic ovary syndrome. Endocr. J 51 (2004) 467-72
    • (2004) Endocr J , vol.51 , pp. 467-472
    • Tarkun, I.1    Canturk, Z.2    Arslan, B.C.3    Turernen, E.4    Tarkun, P.5
  • 112
    • 1842610934 scopus 로고    scopus 로고
    • Hypofiberinolysis in the insulin resistance syndrome: Implication in cardiovascular diseases
    • Mavri A, Alessi MC, Julian-Vague I: Hypofiberinolysis in the insulin resistance syndrome: implication in cardiovascular diseases. J Intern Med 255 (2004) 448-56.
    • (2004) J Intern Med , vol.255 , pp. 448-456
    • Mavri, A.1    Alessi, M.C.2    Julian-Vague, I.3
  • 113
    • 2442580978 scopus 로고    scopus 로고
    • Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome
    • Coughlin S R, Mawdsley L, Mugarza J A, Calverley P M, Wilding J P: Obstructive sleep apnoea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J 25 (2004) 735-741
    • (2004) Eur Heart J , vol.25 , pp. 735-741
    • Coughlin, S.R.1    Mawdsley, L.2    Mugarza, J.A.3    Calverley, P.M.4    Wilding, J.P.5
  • 115
  • 117
    • 0031937519 scopus 로고    scopus 로고
    • Analysis of the relationship between fasting serum uric acid and the insulin sensitivity index in a population-based sample of 380 young healthy Caucasians
    • Clausen J O, Borch-Johnsen K, Ibsen H, Pedersen O: Analysis of the relationship between fasting serum uric acid and the insulin sensitivity index in a population-based sample of 380 young healthy Caucasians. Eur J Endocrinol 138 (1998) 63-9.
    • (1998) Eur J Endocrinol , vol.138 , pp. 63-69
    • Clausen, J.O.1    Borch-Johnsen, K.2    Ibsen, H.3    Pedersen, O.4
  • 118
    • 0012505966 scopus 로고    scopus 로고
    • Relationship of uric acid concentration to cardiovascular risk factors in young men. Role of obesity and central fat distribution. The Verona Young Men Atherosclerosis Risk Factors Study
    • Bonora E, Targher G, Zenere M B, Saggiani F, Cacciatori V, Tosi F, Travia D, Zenti M G, Branzi P, Santi L, Muggeo M: Relationship of uric acid concentration to cardiovascular risk factors in young men. Role of obesity and central fat distribution. The Verona Young Men Atherosclerosis Risk Factors Study. Int J Obes Relat Metab Disord 20 (1996) 975-80
    • (1996) Int J Obes Relat Metab Disord , vol.20 , pp. 975-980
    • Bonora, E.1    Targher, G.2    Zenere, M.B.3    Saggiani, F.4    Cacciatori, V.5    Tosi, F.6    Travia, D.7    Zenti, M.G.8    Branzi, P.9    Santi, L.10    Muggeo, M.11
  • 119
    • 0029887286 scopus 로고    scopus 로고
    • Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population
    • Atherosclerosis Risk in Communities Study Investigators
    • Schmidt M I, Watson R L, Duncan B B, Metcalf P, Brancati F L, Sharrett A R, Davis C E, Heiss G: Clustering of dyslipidemia, hyperuricemia, diabetes, and hypertension and its association with fasting insulin and central and overall obesity in a general population. Atherosclerosis Risk in Communities Study Investigators. Metabolism 45 (1996) 699-706.
    • (1996) Metabolism , vol.45 , pp. 699-706
    • Schmidt, M.I.1    Watson, R.L.2    Duncan, B.B.3    Metcalf, P.4    Brancati, F.L.5    Sharrett, A.R.6    Davis, C.E.7    Heiss, G.8
  • 123
    • 0347513369 scopus 로고    scopus 로고
    • Serum uric acid levels in obese children and adolescents: Linkage to testosterone levels and pre-metabolic syndrome
    • Denzer C, Muche R, Mayer H, Heinze E, Debatin K M, Wabitsch M: Serum uric acid levels in obese children and adolescents: linkage to testosterone levels and pre-metabolic syndrome. J Pediatr Endocrinol Metab 16 (2003) 1225-32
    • (2003) J Pediatr Endocrinol Metab , vol.16 , pp. 1225-1232
    • Denzer, C.1    Muche, R.2    Mayer, H.3    Heinze, E.4    Debatin, K.M.5    Wabitsch, M.6
  • 124
    • 0344033658 scopus 로고    scopus 로고
    • Risk factors for progression to incident hyperinsulinemia: The Atherosclerosis Risk in Communities Study, 1987-1998
    • Carnethon M R, Fortmann S P, Palaniappan L, Duncan B B, Schmidt M I, Chambless L E: Risk factors for progression to incident hyperinsulinemia: the Atherosclerosis Risk in Communities Study, 1987-1998. Am J Epidemiol 158 (2003) 1058-67
    • (2003) Am J Epidemiol , vol.158 , pp. 1058-1067
    • Carnethon, M.R.1    Fortmann, S.P.2    Palaniappan, L.3    Duncan, B.B.4    Schmidt, M.I.5    Chambless, L.E.6
  • 126
  • 127
    • 0026325211 scopus 로고
    • Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration
    • Facchini F, Chen Y D, Hollenbeck C B, Reaven G M: Relationship between resistance to insulin-mediated glucose uptake, urinary uric acid clearance, and plasma uric acid concentration. JAMA 266 (1991) 3008-11
    • (1991) JAMA , vol.266 , pp. 3008-3011
    • Facchini, F.1    Chen, Y.D.2    Hollenbeck, C.B.3    Reaven, G.M.4
  • 128
    • 0242300697 scopus 로고    scopus 로고
    • The coming of age of the metabolic syndrome
    • Alexander C M: The coming of age of the metabolic syndrome. Diabetes Care 26 (2003) 3180-81
    • (2003) Diabetes Care , vol.26 , pp. 3180-3181
    • Alexander, C.M.1
  • 129
    • 0001491077 scopus 로고    scopus 로고
    • Das metabolische syndrom im wandel: Historische perspektive und epidemiologische dimension
    • Hanefeld M, Julius U (ed). Urban & Fischer, München Jena
    • Hanefeld M, Köhler C: Das Metabolische Syndrom im Wandel: Historische Perspektive und epidemiologische Dimension. In: Hanefeld M, Julius U (ed): Das Metabolische Syndrom 2000 - eine postprandiale Krankheit?. Urban & Fischer, München Jena (2001) 15-24
    • (2001) Das Metabolische Syndrom 2000 - Eine Postprandiale Krankheit? , pp. 15-24
    • Hanefeld, M.1    Köhler, C.2


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