Subclinical inflammation is strongly related to insulin resistance but not to impaired insulin secretion in a high risk population for diabetes

Metabolism: Clinical and Experimental

Volumn 51, Issue 6, 2002, Pages 743-749

  Temelkova Kurktschiev, T ^a,b   Siegert, G ^a,b   Bergmann, S ^a,b   Henkel, E ^a,b   Koehler, C ^a,b   Jaross W ^a,b   Hanefeld, M ^a,b  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTILIPEMIC AGENT; C REACTIVE PROTEIN; FATTY ACID; FIBRINOGEN; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LIPID; PROINSULIN; TRIACYLGLYCEROL;

ADULT; AGE; AGED; AGGLUTINATION TEST; ARTICLE; ATHEROSCLEROSIS; BLOOD CLOTTING; BODY MASS; CARDIOVASCULAR DISEASE; CORRELATION ANALYSIS; DIABETES MELLITUS; DYSLIPOPROTEINEMIA; FAMILY HISTORY; FEMALE; FOLLOW UP; GENDER; GLUCOSE BLOOD LEVEL; HIGH RISK POPULATION; HOMEOSTASIS; HUMAN; HYPERLIPOPROTEINEMIA; IMPAIRED GLUCOSE TOLERANCE; INFLAMMATION; INSULIN RELEASE; INSULIN RESISTANCE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; MULTIVARIATE ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PHYSICAL ACTIVITY; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SMOKING;

EID: 0036278738     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2002.32804     Document Type: Article

References (37)

1. Das metabolische syndrom
2. Hyperinsulinaemia: The key feature of a cardiovascular and metabolic syndrome
3. Risk factor clustering in the insulin resistance syndrome: The Strong Heart Study
4. Cardiovascular morbidity and mortality associated with the metabolic syndrome
5. The metabolic syndrome in the West Bank population: An urban-rural comparison
6. Fibrinogen, viscosity, and white blood cell count are major risk factor for ischemic heart disease: The Caerphilly and Speedwell Collaborative Heart Disease Studies
7. White blood cell count and cardiovascular disease: Insights from the Framingham Study
8. Production of C-reactive protein and risk of coronary events in stable and unstable angina
9. Relationship of C-reactive protein to risk of cardiovascular disease in the elderly: Results from the Cardiovascular Health Study and the Rural Health Promotion Project
10. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
11. Lipoprotein-associated phospholipase A2 as an independent predictor of coronary heart disease
12. Inflammation in cardiovascular disease: Cart, horse, or both?
13. Atherosclerosis: An inflammatory disease
14. Association of coronary plaque rupture and atherosclerotic inflammation
15. Pathogenesis of atherosclerosis: A possible relation to infection
16. Chronic infections and the risk of carotid atherosclerosis: Prospective results from a large population study
17. Inflammation is associated with carotid atherosclerosis in dialysis patients. Creed Investigators. Cardiovascular Risk Extended Evaluation in Dialysis Patients
18. Chronic subclinical inflammation as part of the insulin resistance syndrome. The Insulin Resistance Atherosclerosis Study (IRAS)
19. Association between C-reactive protein and features of the metabolic syndrome
20. The white blood cell count: Its relationship to plasma insulin and other cardiovascular risk factors in healthy male individuals
21. C-reactive protein in healthy subjects: Association with obesity, insulin resistance, and endothelial dysfunction: A potent role for cytokines originating from adipose tissue?
22. Chronic activation of the innate immune system may underlie the metabolic syndrome
23. Fibrinogen, other putative markers of inflammation, and weight gain in middle-aged adults - The ARIC study. Atherosclerosis Risk in Communities
24. Addressing the insulin secretion defect. A logical first-line approach
25. Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity
26. Relationship between fasting plasma glucose, atherosclerosis risk factors and carotid intima media thickness in nondiabetic individuals
27. Increased intimal-medial thickness in newly detected type 2 diabetes
28. Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering
29. Effect of statin therapy on C-reactive protein levels: The Pravastatin Inflammation/CRP Evaluation (PRINCE): A randomised trial and cohort study
30. Similar effects of atorvastatin, simvastatin and pravastatin on thrombogenic and inflammatory parameters in patients with hypercholesterolemia
31. The homeostasis model in the San Antonio Heart Study
32. C-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: Results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984-1992
33. C-reactive protein and its relation to cardiovascular risk factors: A population based cross sectional study
34. Is type II diabetes mellitus a disease of the innate immune system?
35. Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha in vivo
36. Evidence for a link between adipose tissue interleukin-6-content and serum C-reactive protein concentrations in obese subjects
37. Tumor necrosis factor alpha: A key component of the obesity-diabetes link