Effect of Moderate Alcohol Consumption on Adiponectin, Tumor Necrosis Factor-α, and Insulin Sensitivity

Diabetes Care

Volumn 27, Issue 1, 2004, Pages 184-189

  Sierksma, Aafje ^a,b   Patel, Hamina ^c   Ouchi, Noriyuki ^d   Kihara, Shinji ^d   Funahashi, Tohru ^d   Heine, Robert J ^e   Grobbee, Diederick E ^b   Kluft, Cornelis ^a   Hendriks, Henk F J ^a  

^a TNO   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c Clinical Studies Department   (United Kingdom)

^d OSAKA UNIVERSITY   (Japan)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ALCOHOL; C PEPTIDE; CHOLESTEROL; CYTOKINE; FATTY ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TAP WATER; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ADULT; ALCOHOL CONSUMPTION; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIABETES MELLITUS; DIET RESTRICTION; GLUCOSE BLOOD LEVEL; HUMAN; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; WHISKEY;

ADIPONECTIN; AGED; ALCOHOL DRINKING; BODY MASS INDEX; BODY WEIGHT; CROSS-OVER STUDIES; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPERINSULINISM; INSULIN; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; PROTEINS; REGRESSION ANALYSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 1042303477     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.27.1.184     Document Type: Article

References (43)

1. Razay G, Heaton KW: Alcohol consumption and its relation to cardiovascular risk factors in British women. BMJ 304:80-83, 1992
2. Mayer EJ, Newman B, Quesenberry CP, Friedman GD, Selby JV: Alcohol consumption and insulin concentrations: role of insulin in associations of alcohol intake with high-density lipoprotein cholesterol and triglycerides. Circulation 88:2190-2197, 1993
3. Facchini F, Chen YD, Reaven GM: Light-to-moderate alcohol intake is associated with enhanced insulin sensitivity. Diabetes Care 17:115-119, 1994
4. Kiechl S, Willeit J, Poewe W, Egger G, Oberhollenzer F, Muggeo M, Bonora E: Insulin sensitivity and regular alcohol consumption: large, prospective, cross sectional population study (Bruneck Study). BMJ 313:1040-1044, 1996
5. Lazarus R, Sparrow D, Weiss ST: Alcohol intake and insulin levels: the Normative Aging Study. Am J Epidemiol 145:909-916, 1997
6. Flanagan DEH, Moore VM, Godsland IF, Cockington RA, Robinson JS, Phillips DI: Alcohol consumption and insulin resistance in young adults. Eur J Clin Invest 30:297-301, 2000
7. Goude D, Fagerberg B, Hulthe J: Alcohol consumption, the metabolic syndrome and insulin resistance in 58-year-old clinically healthy men (AIR study). Clin Sci 102:345-352, 2002
8. Perry IJ, Wannamethee SG, Walker MK, Thomson AG, Whincup PH, Shaper AG: Prospective study of risk factors for development of non-insulin dependent diabetes in middle aged British men. BMJ 310:560-564, 1995
9. Rimm EB, Chan J, Stampfer MJ, Colditz GA, Willett WC: Prospective study of cigarette smoking, alcohol use, and the risk of diabetes in men. BMJ 310:555-559, 1995
10. Ajani UA, Hennekens CH, Spelsberg A, Manson JE: Alcohol consumption and risk of type 2 diabetes mellitus among US male physicians. Arch Intern Med 160:1025-1030, 2000
11. Wei M, Gibbons LW, Mitchell TL, Kampert JB, Blair SN: Alcohol intake and incidence of type 2 diabetes in men. Diabetes Care 23:18-22, 2000
12. Conigrave KM, Hu BF, Camargo CA, Stampfer MJ, Willet WC, Rimm EB: A prospective study of drinking patterns in relation to risk of type 2 diabetes among men. Diabetes 50:2390-2395, 2001
13. De Vegt F, Dekker JM, Groeneveld WJ, Nijpels G, Stehouwer CD, Bouter LM, Heine RJ: Moderate alcohol consumption is associated with lower risk for incident diabetes and mortality: the Hoom Study. Diabetes Res Clin Pract 57:53-60, 2002
14. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni A: Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86:1930-1935, 2001
15. Hotta K, Funahashi T, Bodkin NL, Ortmeyer HK, Arita Y, Hansen BC, Matsuzawa Y: Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50:1126-1133, 2001
16. Cnop M, Havel PJ, Utzschneider KM, Carr DB, Sinha MK, Boyko EJ, Retzlaff BM, Knopp RH, Brunzell JD, Kahn SE: Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex. Diabetologia 46:459-469, 2003
17. Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, Hotta K, Nishida M, Takahashi M, Nakamura T, Yamashita S, Funahashi F, Matsuzawa Y: Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 100:2473-2476, 1999
18. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Himomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y: Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257:79-83, 1999
19. Hotta K, Funahashi T, Arita Y, Takahsashi Y, Matsuda M, Okamoto Y, Iwahashi H, Kuriyama H, Ouchi N, Maeda K, Nishida M, Kihara S, Sakayi N, Nakajima T, Hasegawa K, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Hanafusa T, Matsuzawa Y: Plasma concentrations of a novel adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 20:1595-1599, 2000.
20. Stefan N, Vozarova B, Funahashi T, Matsuzawa Y, Weyer C, Lindsay RS, Youngren JF, Havel PJ, Pratley RE, Bogardus C, Tataranni PA: Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosin phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes 50:1884-1888, 2002
21. Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM: TNF-α inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A 91:4854-4858, 1994
22. Hotamisligil GS, Shargill NS, Spiegelman BM: Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 259:87-91, 1993
23. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM: Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance. J Clin Invest 95:2409-2415, 1995
24. Yokota T, Oritani K, Takahashi I, Ishikawa J, Matsuyama T, Ouchi N, Kihara S, Funahashi T, Tenner AJ, Tomiyama Y, Matsuzawa Y: Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood 96:1723-1732, 2000
25. Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, Hotta K, Nishida M, Takahashi M, Muraguchi M, Ohmoto Y, Nakamura T, Yamashita S, Funahashi T, Matsuzawa Y: Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-κB signaling through a cAMP-dependent pathway. Circulation 102:1296-1301, 2000
26. Kopelman PG: Obesity as a medical problem. Nature 404:635-643, 2000
27. DeFronzo RA, Tobin JD, Andres R: Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 237:E214-E223, 1979
28. Shapiro L, Scherer PE: The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr Biol 12:335-338, 1998
29. Statnick MA, Beavers LS, Conner LJ, Corominola H, Johnson D, Hammond CD, Rafaeloff-Phail R, Seng T, Suter TM, Sluka JP, Ravussin E, Gadski RA, Caro JF: Decreased expression of apM1 in omental and subcutaneous adipose tissue of humans with type 2 diabetes. Int J Reprod Diabetes Res 1:51-58, 2000
30. Yang W, Lee W, Funahashi T, Tanaka S, Matsuzawa Y, Chao C, Chen C, Tai T, Chuang L: Weight reduction increases plasma levels of an adipose-derived antiinflammatory protein, adiponectin. J Clin Endocrinol Metab 86:3815-3819, 2001
31. Hulver MW, Zheng D, Tanner CJ, Houmard JA, Kraus WE, Slentz CA, Sinha MK, Pories WJ, MacDonald KG, Dohm GL: Adiponectin is not altered with exercise training despite enhanced insulin action. Am J Physiol Endocrinol Metab 283: E861-E865, 2002
32. Maeda N, Takahashi M, Funahashi T, Kihara S, Nishizawa H, Kishida K, Nagaretani H, Matsuda M, Komuro R, Ouchi N, Kuriyama H, Hotta K, Nakamura T, Shimomura I, Matsuzawa Y: PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 50:2094-2099, 2001
33. Yang W, Jeng C, Wu T, Tanaka S, Funahashi T, Matsuzawa Y, Wang J, Chen C, Tai T, Chuang L: Synthetic peroxisome proliferator-activated receptor γ agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 25:376-380, 2002
34. Hirose H, Kawai T, Yamamoto Y, Taniyama M, Tomita M, Matsubara K, Okazaki Y, Ishii T, Oguma Y, Takei I, Saruta T: Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes. Metabolism 51:314-317, 2002
35. Yu JG, Javorshi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM: The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 51:2968-2974, 2002
36. Davies MJ, Baer DJ, Judd JT, Brown ED, Campbell WS, Taylor PR: Effects of moderate alcohol intake on fasting insulin and glucose concentrations and insulin sensitivity in postmenopausal women: a randomized controlled trail. JAMA 287:2559-2562, 2002
37. Cordain L, Melby CL, Hamamoto AE, O'Neill DS, Cornier M-A, Barakat HA, Israel RG, Hill JO: Influence of moderate alcohol chronic wine consumption on insulin sensitivity and other correlates of syndrome X in moderately obese women. Metabolism 49:1473-1478, 2000
38. Flanagan DEH, Pratt E, Murphy J, Vaile JC, Petley GW, Godsland IF, Kerr D: Alcohol consumption alters insulin secretion and cardiac autonomic activity. Eur J Clin Invest 32:187-192, 2002
39. Havel PJ: Control of energy homeostasis and insulin action by adipocyte hormones: leptin, acylation stimulating protein, and adiponectin. Curr Opin Lipidol 13:51-59, 2002
40. Ravussin E, Smith SR: Increased fat intake, impaired fat oxidation, and failure of fat cell proliferation result in ectopic fat storage, insulin resistance, and type 2 diabetes mellitus. Ann N Y Acad Sci 967:363-378, 2002
41. Funahashi T, Nakamura T, Shimomura I, Maeda K, Kuriyama H, Takahashi M, Arita Y, Kihara S, Matsuzawa Y: Role of adipocytokines on the pathogenesis of atherosclerosis in visceral obesity. Intern Med 38:202-206, 1999
42. Tschritter O, Fritsche A, Thamer C, Haap M, Shirkavand F, Rahe S, Staiger H, Maerker E, Haring H, Stumvoll M: Plasma adiponectin concentrations predict insulin sensitivity of both glucose and lipid metabolism. Diabetes 52:239-243, 2003
43. Furuhashi M, Ura N, Higashiura K, Murakami H, Tanaka M, Moniwa N, Yoshida D, Shimamoto K: Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension. Hypertension 42:76-81, 2003