Sympathetic neural activation in visceral obesity

Circulation

Volumn 106, Issue 20, 2002, Pages 2533-2536

  Alvarez, Guy E ^a   Beske, Stacy D ^a   Ballard, Tasha P ^a   Davy, Kevin P ^a  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Blood pressure; Nervous system, autonomic; Obesity

Indexed keywords

ADIPOSE TISSUE; ADULT; ARTICLE; BODY COMPOSITION; CARDIOVASCULAR RISK; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DUAL ENERGY X RAY ABSORPTIOMETRY; HUMAN; MALE; NERVE CONDUCTION; NEUROGRAPHY; OBESITY; PRIORITY JOURNAL; SITTING; SUBCUTANEOUS FAT; SYMPATHETIC NERVE;

ABDOMINAL CAVITY; ADIPOSE TISSUE; ADOLESCENT; ADULT; ANTHROPOMETRY; BAROREFLEX; BODY COMPOSITION; HUMANS; MALE; MUSCLE, SKELETAL; OBESITY; SYMPATHETIC NERVOUS SYSTEM;

EID: 0037069321     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000041244.79165.25     Document Type: Article

References (20)

1. Eckel R. Obesity and heart disease: A statement for healthcare professionals from the Nutrition Committee, American Heart Association. Circulation. 1997;96:3248-3250.
2. Flegal KM, Carroll MD, Kuczmarski RJ, et al. Overweight and obesity in the United States: Prevalence and trends, 1960-1994. Int J Obes Relat Metab Disord. 1998;22:39-47.
3. Despres JP, Lemieux I, Prud'homme D. Treatment of obesity: Need to focus on high risk abdominally obese patients. Brit Med J. 2001;322:716-720.
4. Reaven G. Role of insulin resistance in human disease. Diabetes. 1988; 607:1595-1607.
5. Grassi G, Seravalle G, Cattaneo B, et al. Sympathetic activation in obese normotensive subjects. Hypertension. 1995;25:560-563.
6. Grassi G, Seravalle G, Colombo M, et al. Body weight reduction, sympathetic nerve traffic, and arterial baroreflex in obese normotensive humans. Circulation. 1998;97:2037-2042.
7. Grassi G, Seravalle G, Dell'Oro R, et al. Participation of the hypothalamus-hypophysis axis in the sympathetic activation of human obesity. Hypertension. 2001;38:1316-1320.
8. Scherrer U, Randin D, Tappy L, et al. Body fat and sympathetic nerve activity in healthy subjects. Circulation. 1994;89:2634-2640.
9. Spraul M, Ravussin E, Fontvieille A, et al. Reduced sympathetic nervous activity: A potential mechanism predisposing to body weight gain. J Clin Invest. 1993;92:1730-1735.
10. Beske SD, Alvarez GE, Ballard TP, et al. Reduced cardiovagal baroreflex gain in visceral obesity: Implications for the metabolic syndrome. Am J Physiol. 2002;282:H630-H635.
11. Davy KP, Seals DR, Tanaka H. Augmented cardiopulmonary and intergrative baroreflexes but attenuated peripheral vasoconstriction with age. Hypertension. 1998;32:298-304.
12. Wallin BG, Fagius J. Peripheral sympathetic neural activity in conscious humans. Ann Rev Physiol. 1988;50:565-576.
13. Ebert TJ, Cowley AW Jr. Baroreflex modulation of sympathetic outflow during physiological increases of vasopressin in humans. Am J Physiol. 1992;262:H1372-H1378.
14. Halliwill JR. Segregated signal averaging of sympathetic baroreflex responses in humans. J Appl Physiol. 2000;88:767-73.
15. Bjorntorp P, Rosmond R. Neuroendocrine abnormalities in visceral obesity. Int J Obes Relat Metab Disord. 2000;24(suppl 2):S80-S85.
16. Jones PP, Davy KP, Alexander S, et al. Age-related increase in muscle sympathetic nerve activity is associated with abdominal adiposity. Am J Physiol. 1997;272:E976-E980.
17. Jones PP, Davy KP, Seals DR. Relations of total and abdominal adiposity to muscle sympathetic nerve activity in healthy older males. Int J Obes Relat Metab Disord. 1997;21:1053-1057.
18. Reaven G. Metabolic syndrome: Pathophysiology and implications for management of cardiovascular disease. Circulation. 2002;106:286-288.
19. Esler M. Sympathetic nervous system: Contribution to hypertension and related cardiovascular disease. J Cardiovasc Pharmacol. 1995;26:S24-S28.
20. Narkiewicz K, van de Borne PJ, Cooley RL, et al. Sympathetic activity in obese subjects with and without obstructive sleep apnea. Circulation. 1998;98:772-776.