Insulin Sensitivity, Insulinemia, and Coronary Artery Disease: The Insulin Resistance Atherosclerosis Study

Diabetes Care

Volumn 27, Issue 3, 2004, Pages 781-787

  Rewers, Marian ^a   Zaccaro, Daniel ^b   D'Agostino Jr , Ralph ^b   Haffner, Steven ^c   Saad, Mohammed F ^d   Selby, Joe V ^e   Bergman, Richard ^f   Savage, Peter ^g  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^f DIVISION OF RESEARCH   (United States)

^g NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CIGARETTE SMOKING; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSLIPIDEMIA; FEMALE; GLUCOSE TOLERANCE TEST; HEART INFARCTION; HUMAN; HYPERTENSION; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INSULINEMIA; MAJOR CLINICAL STUDY; MALE; OBESITY; Q WAVE; RISK FACTOR; TRANSLUMINAL CORONARY ANGIOPLASTY;

ADULT; AGED; BLOOD GLUCOSE; CONTINENTAL POPULATION GROUPS; CORONARY DISEASE; ETHNIC GROUPS; FASTING; FEMALE; GLUCOSE INTOLERANCE; HUMANS; INSULIN; MALE; MIDDLE AGED; ODDS RATIO; RISK FACTORS; SMOKING; UNITED STATES;

EID: 1442275321     PISSN: 01495992     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.27.3.781     Document Type: Article

References (41)

1. Reaven GM: Role of insulin resistance in human disease. Diabetes 37:326-337, 1988
2. DeFronzo RA, Ferrannini E: Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease. Diabetes Care 14:173-194, 1991
3. Young MH, Jeng CY, Sheu WH, Shieh SM, Fuh MM, Chen YD, Reaven GM: Insulin resistance, glucose intolerance, hyperin-sulinemia and dyslipidemia in patients with angiographically demonstrated coronary artery disease. Am J Cardiol 72:458-460, 1993
4. Shinozaki K, Suzuki M, Ikebuchi M, Hara Y, Harano Y: Demonstration of insulin resistance in coronary artery disease documented with angiography. Diabetes Care 19:1-7, 1996
5. Bressler P, Bailey SR, Matsuda M, DeFronzo RA: Insulin resistance and coronary artery disease. Diabetologia 39:1345-1350, 1996
6. Welborn TA, Wearne K: Coronary heart disease incidence and cardiovascular mortality in Busselton with reference to glucose and insulin concentrations. Diabetes Care 2:154-160, 1979
7. Pyörälä M, Miettinen H, Laakso M, Pyörälä K: Hyperinsulinemia predicts coronary heart disease risk in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study. Circulation 98:398-404, 1998
8. Eschwege E, Ducimetiere P, Thibult N, Richard JL, Claude JR, Rosselin GE: Coronary heart disease mortality in relation with diabetes, blood glucose and plasma insulin levels: the Paris prospective study 10 years later. Horm Metab Res 15 (Suppl.):41-45, 1985
9. Yarnell JWG, Sweetnam PM, Marks V, Teale JD, Bolton CH: Insulin in ischaemic heart disease: are associations explained by triglyceride concentrations: the Caerpholly prospective study. Br Heart J 171:293-296, 1994
10. Perry IJ, Wannamethee SG, Whincup PH, Shaper AG, Walker MK, Alberti KGMM: Serum insulin and incident coronary heart disease in middle-aged British men. Am J Epidemiol 144:224-234, 1996
11. Després J-P, Lamarche B, Mauriège P, Cantin B, Dagenais GR, Moorjani S, Lupien PJ: Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 334:952-957, 1996
12. Folsom AR, Liao F, Szklo M, Smith R, Stevens J, Eckfeldt JH: A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes. Diabetes Care 20:935-942, 1997
13. Stout RW: Insulin and atheroma: 20-year perspective. Diabetes Care 13:631-655, 1990
14. Kahn SSE, Prigeon RL, McCulloch DK, Boyko EJ, Bergman RN, Schwartz MW, Neifing JL, Ward WK, Beard JC, Palmer JP, Porte D Jr: Quantification of the relationship between insulin sensitivity and β-cell function in human subjects: evidence for a hyperbolic function. Diabetes 42:1663-1672, 1993
15. Laakso M: How good a marker is insulin level for insulin resistance? Am J Epidemiol 137:959-965, 1993
16. Ludvik B, Nolan JJ, Baloga J, Sacks D, Olefsky J: Effect of obesity on insulin resistance in normal subjects and patients with NIDDM. Diabetes 44:1121-1125, 1995
17. Howard G, O'Leary DH, Zaccaro D, Haffner S, Rewers M, Hamman R, Selby JV, Saad MF, Savage PJ, Bergman R: Insulin sensitivity and atherosclerosis. Circulation 93:1809-1817, 1996
18. Watarai T, Yamasaki Y, Ikeda M, Kubota M, Kodama M, Tsujino T, Kishimoto M, Kawamori R, Hori M: Insulin resistance contributes to carotid arterial wall thickness in patients with non-insulin-dependent-diabetes mellitus. Endocr J 46:629-638, 1999
19. Wohlin M, Sundstrom J, Arnlov J, Andren B, Zethelius B, Lind L: Impaired insulin sensitivity is an independent predictor of common carotid intima-media thickness in a population sample of elderly men. Atherosclerosis 170:181-185, 2003
20. Wagenknecht LE, Mayer EJ, Rewers MR, Haffner S, Selby J, Borok GM, Henkin L, Howard G, Savage PJ, Saad MF, Bergman RN, Hamman R: The Insulin Resistance Atherosclerosis Study (IRAS): Objectives, design, and recruitment results. Ann Epidemiol 5:464-472, 1995
21. Stern MP, Rosenthal M, Haffner SM, Hazuda HP, Franco LJ: Sex differences in the effects of sociocultural status on diabetes and cardiovascular risk factors in Mexican Americans: the San Antonio Heart Study. Am J Epidemiol 120:834-851, 1984
22. Hamman RF, Marshall JA, Baxter J, Kahn LB, Mayer EJ, Orleans M, Murphy JR, Lezotte DC: Methods and prevalence of non-insulin dependent diabetes mellitus in a biethnic Colorado population: the San Luis Valley Diabetes Study. Am J Epidemiol 129:295-311, 1989
23. World Health Organization: Diabetes Mellitus: Report of a WHO Study Group. Geneva, World Health Org., 1985 (Tech. Rep. Ser., no. 727)
24. Herbert V, Lau K, Gottlieb C, Bleicher S: Coated charcoal immunoassay of insulin. J Endocrinol Metab 25:1375-1384, 1965
25. Bergman RN, Finegood DT, Ader M: Assessment of insulin sensitivity in vivo. Endocr Rev 6:45-86, 1985
26. Welch S, Gebhart SSP, Bergman RN, Phillips LS: Minimal model analysis of intravenous glucose tolerance derived insulin sensitivity in diabetic subjects. J Endocrinol Metab 71:1508-1518, 1990
27. Saad MF, Anderson RL, Laws A, Watanabe RM, Kades WW, Chen Y-DI, Sands RE, Pei D, Savage PJ, Bergman RN: A comparison between the minimal model and glucose clamp in the assessment of insulin sensitivity across the spectrum of glucose tolerance. Diabetes 43:1114-1121, 1994
28. The ARIC Investigators: The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. Am J Epidemiol 129:687-702, 1989
29. Prineas RJ, Crow RS, Blackburn H: The Minnesota Code: Manual of Electrographic Findings. Boston, John Wright-PGS, 1982
30. Wingard DL, Ferrara A, Barrett-Connor EL: Is insulin really a heart disease risk factor? Diabetes Care 18:1299-1304, 1995
31. Ferrannini E, Buzzigoli G, Bonadonna R, Giorco MA, Oleggini M, Graziadei L, Pedrinnelli R, Brandi L, Bevilacqua S: Insulin resistance in essential hypertension. N Engl J Med 317:350-357, 1987
32. Orchard TJ, Becker DJ, Bates M, Kuller LH, Drash AL: Plasma insulin and lipoprotein concentrations: an atherogenic association? Am J Epidemiol 118:326-337, 1983
33. Barrett-Connor E: Does hyperglycemia really cause coronary heart disease? Diabetes Care 20:1620-1623, 1997
34. Lehto S, Rönnemaa T, Haffner SM, Pyörälä K, Kallio V, Laakso M: Dyslipidemia and hyperglycemia predict coronary heart disease events in middle-aged patients with NIDDM. Diabetes 46:1354-1359, 1997
35. Wingard DL, Barrett-Connor E: Heart disease and diabetes. In Diabetes in America. Ed 2. Bethesda, MD, NIH, NIDDK, 1995, p. 429-548 (NIH publ. no. 95-1468)
36. King H, Rewers M, for WHO Ad Hoc Diabetes Reporting Group: Global estimates for prevalence of diabetes and impaired glucose tolerance in adults. Diabetes Care 16:157-177, 1993
37. I = 0) in diabetic and nondiabetic subjects in the insulin resistance atherosclerosis study: is it associated with components of the metabolic syndrome and nontraditional risk factors? Diabetes Care 26:2796-2803, 2003
38. Ni T-C, Ader M, Bergman RN: Reassessment of glucose effectiveness and insulin sensitivity from minimal model analysis: the effect of single compartment glucose distribution assumption. Diabetes 46:1813-1821, 1997
39. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner R: Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419, 1985
40. Van Cauter E, Polonsky KS, Scheen AJ: Roles of circadian rhythmicity and sleep in human glucose regulation. Endocr Rev 18:716-738, 1997
41. Olefsky JM, Reaven GM: Insulin and glucose responses to identical oral glucose tolerance test performed 48 hours apart. Diabetes 23:449-453, 1974