-
1
-
-
0142026180
-
Context-dependent transcription: All politics is local
-
Alvarez M, Rhodes SJ, Bidwell JP (2003) Context-dependent transcription: all politics is local. Gene 313:43-57
-
(2003)
Gene
, vol.313
, pp. 43-57
-
-
Alvarez, M.1
Rhodes, S.J.2
Bidwell, J.P.3
-
3
-
-
31844449923
-
Gene network shaping of inherent noise spectra
-
Austin DW, Allen MS, McCollum JM, Dar RD, Wilgus JR, Sayler GS, Samatova NF, Cox CD, Simpson ML (2006) Gene network shaping of inherent noise spectra. Nature 439:608-611
-
(2006)
Nature
, vol.439
, pp. 608-611
-
-
Austin, D.W.1
Allen, M.S.2
McCollum, J.M.3
Dar, R.D.4
Wilgus, J.R.5
Sayler, G.S.6
Samatova, N.F.7
Cox, C.D.8
Simpson, M.L.9
-
4
-
-
6344238781
-
Synthetic biology: Starting from scratch
-
Ball P (2004) Synthetic biology: starting from scratch. Nature 431:624-626
-
(2004)
Nature
, vol.431
, pp. 624-626
-
-
Ball, P.1
-
5
-
-
12344295408
-
Synthetic biology for nanotechnology
-
Ball P (2005) Synthetic biology for nanotechnology. Nanotechnology 16:R1-R8
-
(2005)
Nanotechnology
, vol.16
-
-
Ball, P.1
-
6
-
-
17844374314
-
A synthetic multicellular system for programmed pattern formation
-
Basu S, Gerchman Y, Collins CH, Arnold FH, Weiss R (2005) A synthetic multicellular system for programmed pattern formation. Nature 434:1130-1134
-
(2005)
Nature
, vol.434
, pp. 1130-1134
-
-
Basu, S.1
Gerchman, Y.2
Collins, C.H.3
Arnold, F.H.4
Weiss, R.5
-
7
-
-
6944225455
-
Understanding nucleic acids using synthetic chemistry
-
Benner SA (2004) Understanding nucleic acids using synthetic chemistry. Acc Chem Res 37:784-797
-
(2004)
Acc Chem Res
, vol.37
, pp. 784-797
-
-
Benner, S.A.1
-
10
-
-
5044239903
-
A partnership between biology and engineering
-
Brent R (2004) A partnership between biology and engineering. Nat Biotechnol 22:1211-1214
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1211-1214
-
-
Brent, R.1
-
11
-
-
24644503579
-
The beta alpha beta alpha beta alpha elementary Supersecondary structure of the Rossmann fold from porcine lactate dehydrogenase exhibits characteristics of a molten globule
-
Coincon M, Heitz A, Chiche L, Derreumaux P (2005) The beta alpha beta alpha beta alpha elementary Supersecondary structure of the Rossmann fold from porcine lactate dehydrogenase exhibits characteristics of a molten globule. Proteins Struct Funct Bioinform 60:740-745
-
(2005)
Proteins Struct Funct Bioinform
, vol.60
, pp. 740-745
-
-
Coincon, M.1
Heitz, A.2
Chiche, L.3
Derreumaux, P.4
-
12
-
-
13244281560
-
Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor
-
Dattelbaum JD, Looger LL, Benson DE, Sali KM, Thompson RB, Hellinga HW (2005) Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor. Protein Sci 14:284-291
-
(2005)
Protein Sci
, vol.14
, pp. 284-291
-
-
Dattelbaum, J.D.1
Looger, L.L.2
Benson, D.E.3
Sali, K.M.4
Thompson, R.B.5
Hellinga, H.W.6
-
14
-
-
3042655537
-
Computational design of a biologically active enzyme
-
Dwyer MA, Looger LL, Hellinga HW (2004) Computational design of a biologically active enzyme. Science 304:1967-1971
-
(2004)
Science
, vol.304
, pp. 1967-1971
-
-
Dwyer, M.A.1
Looger, L.L.2
Hellinga, H.W.3
-
15
-
-
28544451327
-
Foundations for engineering biology
-
Endy D (2005) Foundations for engineering biology. Nature 438:449-453
-
(2005)
Nature
, vol.438
, pp. 449-453
-
-
Endy, D.1
-
16
-
-
0034625007
-
Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes
-
Endy D, You L, Yin J, Molineux IJ (2000) Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes. Proc Natl Acad Sci USA 97:5375-5380
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 5375-5380
-
-
Endy, D.1
You, L.2
Yin, J.3
Molineux, I.J.4
-
17
-
-
0346095503
-
Synthetic biology. Microbes made to order
-
Ferber D (2004) Synthetic biology. Microbes made to order. Science 303:158-161
-
(2004)
Science
, vol.303
, pp. 158-161
-
-
Ferber, D.1
-
20
-
-
31044439550
-
Essential genes of a minimal bacterium
-
Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA 3rd, Smith HO, Venter JC (2006) Essential genes of a minimal bacterium. Proc Natl Acad Sci USA 103:425-430
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 425-430
-
-
Glass, J.I.1
Assad-Garcia, N.2
Alperovich, N.3
Yooseph, S.4
Lewis, M.R.5
Maruf, M.6
Hutchison III, C.A.7
Smith, H.O.8
Venter, J.C.9
-
21
-
-
0025040232
-
De novo design, expression, and characterization of Felix: A four-helix bundle protein of native-like sequence
-
Hecht MH, Richardson JS, Richardson DC, Ogden RC (1990) De novo design, expression, and characterization of Felix: a four-helix bundle protein of native-like sequence. Science 249:884-891
-
(1990)
Science
, vol.249
, pp. 884-891
-
-
Hecht, M.H.1
Richardson, J.S.2
Richardson, D.C.3
Ogden, R.C.4
-
22
-
-
33645694379
-
A promiscuous glutathione transferase transformed into a selective thiolester hydrolase
-
Hederos S, Tegler L, Carlsson J, Persson B, Viljanen J, Broo KS (2006) A promiscuous glutathione transferase transformed into a selective thiolester hydrolase. Org Biomol Chem 4:90-97
-
(2006)
Org Biomol Chem
, vol.4
, pp. 90-97
-
-
Hederos, S.1
Tegler, L.2
Carlsson, J.3
Persson, B.4
Viljanen, J.5
Broo, K.S.6
-
23
-
-
21444454396
-
Synthetic biology offers alternative pathways to natural products
-
Herrera S (2005) Synthetic biology offers alternative pathways to natural products. Nat Biotechnol 23:270-271
-
(2005)
Nat Biotechnol
, vol.23
, pp. 270-271
-
-
Herrera, S.1
-
24
-
-
9344235017
-
Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels
-
Hocker B, Claren J, Sterner R (2004) Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels. Proc Natl Acad Sci USA 101:16448-16453
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16448-16453
-
-
Hocker, B.1
Claren, J.2
Sterner, R.3
-
25
-
-
0141483011
-
Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins
-
Howard PL, Chia MC, Del Rizzo S, Liu FF, Pawson T (2003) Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins. Proc Natl Acad Sci USA 100:11267-11272
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 11267-11272
-
-
Howard, P.L.1
Chia, M.C.2
Del Rizzo, S.3
Liu, F.F.4
Pawson, T.5
-
26
-
-
8144226497
-
Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster
-
Kodumal SJ, Patel KG, Reid R, Menzella HG, Welch M, Santi DV (2004) Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster. Proc Natl Acad Sci USA 101:15573-15578
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15573-15578
-
-
Kodumal, S.J.1
Patel, K.G.2
Reid, R.3
Menzella, H.G.4
Welch, M.5
Santi, D.V.6
-
27
-
-
0036228521
-
Engineering a reduced Escherichia coli genome
-
Kolisnychenko V, Plunkett G 3rd, Herring CD, Feher T, Posfai J, Blattner FR, Posfai G (2002) Engineering a reduced Escherichia coli genome. Genome Res 12:640-647
-
(2002)
Genome Res
, vol.12
, pp. 640-647
-
-
Kolisnychenko, V.1
Plunkett III, G.2
Herring, C.D.3
Feher, T.4
Posfai, J.5
Blattner, F.R.6
Posfai, G.7
-
28
-
-
2642670311
-
Design of a 20-amino acid, three-stranded beta-sheet protein
-
Kortemme T, Ramirez-Alvarado M, Serrano L (1998) Design of a 20-amino acid, three-stranded beta-sheet protein. Science 281:253-256
-
(1998)
Science
, vol.281
, pp. 253-256
-
-
Kortemme, T.1
Ramirez-Alvarado, M.2
Serrano, L.3
-
29
-
-
24044457608
-
Semi-synthetic mammalian gene regulatory networks
-
Kramer BP, Fischer M, Fussenegger M (2005) Semi-synthetic mammalian gene regulatory networks. Metab Eng 7:241-250
-
(2005)
Metab Eng
, vol.7
, pp. 241-250
-
-
Kramer, B.P.1
Fischer, M.2
Fussenegger, M.3
-
30
-
-
0345306764
-
Design of a novel globular protein fold with atomic-level accuracy
-
Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D (2003) Design of a novel globular protein fold with atomic-level accuracy. Science 302:1364-1368
-
(2003)
Science
, vol.302
, pp. 1364-1368
-
-
Kuhlman, B.1
Dantas, G.2
Ireton, G.C.3
Varani, G.4
Stoddard, B.L.5
Baker, D.6
-
31
-
-
1842484779
-
Designing materials for biology and medicine
-
Langer R, Tirrell DA (2004) Designing materials for biology and medicine. Nature 428:487-492
-
(2004)
Nature
, vol.428
, pp. 487-492
-
-
Langer, R.1
Tirrell, D.A.2
-
32
-
-
28544442417
-
Synthetic biology: Engineering Escherichia coli to see light
-
Levskaya A, Chevalier AA, Tabor JJ, Simpson ZB, Lavery LA, Levy M, Davidson EA, Scouras A, Ellington AD, Marcotte EM, Voigt CA (2005) Synthetic biology: engineering Escherichia coli to see light. Nature 438:441-442
-
(2005)
Nature
, vol.438
, pp. 441-442
-
-
Levskaya, A.1
Chevalier, A.A.2
Tabor, J.J.3
Simpson, Z.B.4
Lavery, L.A.5
Levy, M.6
Davidson, E.A.7
Scouras, A.8
Ellington, A.D.9
Marcotte, E.M.10
Voigt, C.A.11
-
33
-
-
0036468436
-
The modular logic of signaling proteins: Building allosteric switches from simple binding domains
-
Lim WA (2002) The modular logic of signaling proteins: building allosteric switches from simple binding domains. Curr Opin Struct Biol 12:61-68
-
(2002)
Curr Opin Struct Biol
, vol.12
, pp. 61-68
-
-
Lim, W.A.1
-
34
-
-
0034612192
-
Inaugural article: Retrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteins
-
Lombardi A, Summa CM, Geremia S, Randaccio L, Pavone V, DeGrado WF (2000) Inaugural article: retrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteins. Proc Natl Acad Sci USA 97:6298-6305
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6298-6305
-
-
Lombardi, A.1
Summa, C.M.2
Geremia, S.3
Randaccio, L.4
Pavone, V.5
DeGrado, W.F.6
-
35
-
-
19144366814
-
Metagenomics and industrial applications
-
Lorenz P, Eck J (2005) Metagenomics and industrial applications. Nat Rev Microbiol 3:510-516
-
(2005)
Nat Rev Microbiol
, vol.3
, pp. 510-516
-
-
Lorenz, P.1
Eck, J.2
-
36
-
-
31344455122
-
Approaches to semi-synthetic minimal cells: A review
-
Luisi PL, Ferri F, Stano P (2006) Approaches to semi-synthetic minimal cells: a review. Naturwissenschaften 93:1-13
-
(2006)
Naturwissenschaften
, vol.93
, pp. 1-13
-
-
Luisi, P.L.1
Ferri, F.2
Stano, P.3
-
37
-
-
23444461901
-
Advances in synthetic biology: On the path from prototypes to applications
-
McDaniel R, Weiss R (2005) Advances in synthetic biology: on the path from prototypes to applications. Curr Opin Biotechnol 16:476-483
-
(2005)
Curr Opin Biotechnol
, vol.16
, pp. 476-483
-
-
McDaniel, R.1
Weiss, R.2
-
38
-
-
29944438701
-
Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster
-
Menzella HG, Reisinger SJ, Welch M, Kealey JT, Kennedy J, Reid R, Tran CQ, Santi DV (2006) Redesign, synthesis and functional expression of the 6-deoxyerythronolide B polyketide synthase gene cluster. J Ind Microbiol Biotechnol 33:22-28
-
(2006)
J Ind Microbiol Biotechnol
, vol.33
, pp. 22-28
-
-
Menzella, H.G.1
Reisinger, S.J.2
Welch, M.3
Kealey, J.T.4
Kennedy, J.5
Reid, R.6
Tran, C.Q.7
Santi, D.V.8
-
39
-
-
16244402638
-
Advances in biocatalytic synthesis of pharmaceutical intermediates
-
Panke S, Wubbolts M (2005) Advances in biocatalytic synthesis of pharmaceutical intermediates. Curr Opin Chem Biol 9:188-194
-
(2005)
Curr Opin Chem Biol
, vol.9
, pp. 188-194
-
-
Panke, S.1
Wubbolts, M.2
-
41
-
-
31544477181
-
Design and evolution of new catalytic activity with an existing protein scaffold
-
Park HS, Nam SH, Lee JK, Yoon CN, Mannervik B, Benkovic SJ, Kim HS (2006) Design and evolution of new catalytic activity with an existing protein scaffold. Science 311:535-538
-
(2006)
Science
, vol.311
, pp. 535-538
-
-
Park, H.S.1
Nam, S.H.2
Lee, J.K.3
Yoon, C.N.4
Mannervik, B.5
Benkovic, S.J.6
Kim, H.S.7
-
42
-
-
14844321287
-
Synthetic modular systems - Reverse engineering of signal transduction
-
Pawson T, Linding R (2005) Synthetic modular systems - reverse engineering of signal transduction. FEBS Lett 579:1808-1814
-
(2005)
FEBS Lett
, vol.579
, pp. 1808-1814
-
-
Pawson, T.1
Linding, R.2
-
44
-
-
29344453148
-
Cellular logic with orthogonal ribosomes
-
Rackham O, Chin JW (2005) Cellular logic with orthogonal ribosomes. J Am Chem Soc 127:17584-17585
-
(2005)
J Am Chem Soc
, vol.127
, pp. 17584-17585
-
-
Rackham, O.1
Chin, J.W.2
-
46
-
-
0037447260
-
Frequency domain analysis of noise in autoregulated gene circuits
-
Simpson ML, Cox CD, Sayler GS (2003) Frequency domain analysis of noise in autoregulated gene circuits. Proc Natl Acad Sci USA 100:4551-4556
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 4551-4556
-
-
Simpson, M.L.1
Cox, C.D.2
Sayler, G.S.3
-
47
-
-
0347364647
-
Generating a synthetic genome by whole genome assembly: PhiX174 bacteriophage from synthetic oligonucleotides
-
Smith HO, Hutchison CA 3rd, Pfannkoch C, Venter JC (2003) Generating a synthetic genome by whole genome assembly: phiX174 bacteriophage from synthetic oligonucleotides. Proc Natl Acad Sci USA 100:15440-15445
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15440-15445
-
-
Smith, H.O.1
Hutchison III, C.A.2
Pfannkoch, C.3
Venter, J.C.4
-
48
-
-
28544440364
-
Reconstruction of genetic circuits
-
Sprinzak D, Elowitz MB (2005) Reconstruction of genetic circuits. Nature 438:443-448
-
(2005)
Nature
, vol.438
, pp. 443-448
-
-
Sprinzak, D.1
Elowitz, M.B.2
-
49
-
-
4544231739
-
Site-specific incorporation of unnatural amino acids into proteins
-
Stromgaard A, Jensen AA, Stromgaard K (2004) Site-specific incorporation of unnatural amino acids into proteins. Chembiochem 5:909-916
-
(2004)
Chembiochem
, vol.5
, pp. 909-916
-
-
Stromgaard, A.1
Jensen, A.A.2
Stromgaard, K.3
-
51
-
-
11144247743
-
Accurate multiplex gene synthesis from programmable DNA microchips
-
Tian J, Gong H, Sheng N, Zhou X, Gulari E, Gao X, Church G (2004) Accurate multiplex gene synthesis from programmable DNA microchips. Nature 432:1050-1054
-
(2004)
Nature
, vol.432
, pp. 1050-1054
-
-
Tian, J.1
Gong, H.2
Sheng, N.3
Zhou, X.4
Gulari, E.5
Gao, X.6
Church, G.7
-
52
-
-
27844496157
-
An active enzyme constructed from a 9-amino acid alphabet
-
Walter KU, Vamvaca K, Hilvert D (2005) An active enzyme constructed from a 9-amino acid alphabet. J Biol Chem 280:37742-37746
-
(2005)
J Biol Chem
, vol.280
, pp. 37742-37746
-
-
Walter, K.U.1
Vamvaca, K.2
Hilvert, D.3
-
54
-
-
27744485401
-
Adding amino acids to the genetic repertoire
-
Xie J, Schultz PG (2005) Adding amino acids to the genetic repertoire. Curr Opin Chem Biol 9:548-554
-
(2005)
Curr Opin Chem Biol
, vol.9
, pp. 548-554
-
-
Xie, J.1
Schultz, P.G.2
-
56
-
-
33645405075
-
Rational design of macrolides by virtual screening of combinatorial libraries generated through in silico manipulation of polyketide synthases
-
Zotchev SB, Stepanchikova AV, Sergeyko AP, Sobolev BN, Filimonov DA, Poroikov VV (2006) Rational design of macrolides by virtual screening of combinatorial libraries generated through in silico manipulation of polyketide synthases. J Med Chem 49:2077-2087
-
(2006)
J Med Chem
, vol.49
, pp. 2077-2087
-
-
Zotchev, S.B.1
Stepanchikova, A.V.2
Sergeyko, A.P.3
Sobolev, B.N.4
Filimonov, D.A.5
Poroikov, V.V.6
|