An active enzyme constructed from a 9-amino acid alphabet

Journal of Biological Chemistry

Volumn 280, Issue 45, 2005, Pages 37742-37746

  Walter, Kai U ^a   Vamvaca, Katherina ^a   Hilvert, Donald ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CATALYSTS; CELLS; CYTOLOGY; ENZYMES; MOLECULAR BIOLOGY;

AUXOTROPHIC CELLS; CHORISMATE MUTASE; COMBINATORIAL ENGINEERING; PROTEIN STRUCTURES;

ENZYME KINETICS;

AMINO ACID; CHORISMATE MUTASE;

AMINO ACID COMPOSITION; ARTICLE; CATALYST; COMBINATORIAL LIBRARY; ENZYME STRUCTURE; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN STABILITY; PROTEIN STRUCTURE;

AMINO ACID SEQUENCE; AMINO ACIDS; CHORISMATE MUTASE; ENZYME STABILITY; EVOLUTION, MOLECULAR; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PLIABILITY; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE;

EID: 27844496157     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M507210200     Document Type: Article

References (32)

1. Davis, B. K. (2002) Prog. Biophys. Mol. Biol. 79, 77-133
2. Regan, L., and DeGrado, W. F. (1988) Science 241, 976-978
3. Kamtekar, S., Schiffer, J. M., Xiong, H., Babik, J. M., and Hecht, M. H. (1993) Science 262, 1680-1685
4. Davidson, A. R., Lumb, K. J., and Sauer, R. T. (1995) Nat. Struct. Biol. 2, 856-863
5. Schafmeister, C. E., LaPorte, S. L., Miercke, L. J. W., and Stroud, R. M. (1997) Nat. Struct. Biol. 4, 1039-1046
6. Riddle, D. S., Santiago, J. V., Bray-Hall, S. T., Doshi, N., Grantcharova, V. P.,Yi, Q., and Baker, D. (1997) Nat Struct. Biol. 1, 805-809
7. Silverman, J. A., Balakrishnan, R., and Harbury, P. B. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 3092-3097
8. Akanuma, S., Kigawa, T., and Yokoyama, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13549-13553
9. Taylor, S. V., Walter, K. U., Kast, P., and Hilvert, D. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 10596-10601
10. Kast, P., Asif-Ullah, M., Jiang, N., and Hilvert, D. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5043-5048
11. MacBeath, G., and Kast, P. (1998) BioTechniques 24, 789-794
12. MacBeath, G., Kast, P., and Hilvert, D. (1998) Biochemistry 37, 10062-10073
13. Bartlett, P. A., and Johnson, C. R. (1985) J. Am. Chem. Soc. 107, 7792-7793
14. Vamvaca, K., Vögeli, B., Kast, P., Pervushin, K., and Hilvert, D. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 12860-12864
15. Lee, A. Y., Karplus, P. A., Ganem, B., and Clardy, J. (1995) J. Am. Chem. Soc. 117, 3627-3628
16. Firth, A E., and Patrick, W. M. (2005) Bioinformatics (Oxf.) 21, 3314-3315
17. Zhang, S., Kongsaeree, P., Clardy, J., Wilson, D. B., and Ganem, B. (1996) Bioorg. Med. Chem. 4, 1015-1020
18. Smith, D. L., Deng, Y., and Zhang, Z. (1997) J. Mass Spectrom. 32, 135-146
19. Stryer, L. (1968) Science 162, 526-533
20. Ptitsyn, O. B., Pain, R. H., Semisotnov, G. V., Zerovnik, E., and Razgulyaev, O. I. (1990) FEBS Lett. 262, 20-24
21. Betz, S. F., Raleigh, D. P., and DeGrado, W. F. (1993) Curr. Opin. Struct. Biol. 3, 601-610
22. MacBeath, G., Kast, P., and Hilvert, D. (1998) Science 279, 1958-1961
23. Creighton, T. E. (1993) Proteins: Structures and Molecular Properties, 2nd Ed., pp. 171-260, W. H. Freeman, New York
24. Wang, J., and Wang, W. (1999) Nat. Struct. Biol. 6, 1033-1038
25. Taylor, S. V., Kast, P., and Hilvert, D. (2001) Angew. Chem. Int. Ed. Engl. 40, 3311-3335
26. Chook, Y. M., Ke, H., and Lipscomb, W. N. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 8600-8603
27. Haynes, M. R., Stura, E. A., Hilvert, D., and Wilson, I. A. (1994) Science 263, 646-652
28. Dahiyat, B. I., and Mayo, S. L. (1997) Science 278, 82-87
29. Kuhlman, B., Dantas, G., Ireton, G. C., Varani, G., Stoddard, B. L., and Baker, D. (2003) Science 302, 1364-1368
30. Harbury, P. B., Plecs, J. J., Tidor, B., Alber, T., and Kim, P. S. (1998) Science 282, 1462-1467
31. Looger, L. L., Dwyer, M. A., Smith, J. J., and Hellinga, H. W. (2003) Nature 185-190
32. Dwyer, M. A., Looger, L. L., and Hellinga, H. W. (2004) Science 304, 1967-1971