Analysis of allosteric signal transduction mechanisms in an engineered fluorescent maltose biosensor

Protein Science

Volumn 14, Issue 2, 2005, Pages 284-291

  Dattelbaum, Jonathan D ^a   Logger, Loren L ^a   Benson, David E ^b   Sali, Kevin M ^a   Thompson, Richard B ^c   Hellinga, Homme W ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Allosteric mechanism; Biosensors; Fluorescence; Maltose binding protein; Periplasmic binding proteins; Protein design

Indexed keywords

BINDING PROTEIN; MALTOSE; MALTOSE BINDING PROTEIN; PERIPLASMIC BINDING PROTEIN;

ALLOSTERISM; ARTICLE; BIOSENSOR; CRYSTAL STRUCTURE; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; HYDROGEN BOND; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; BIOSENSING TECHNIQUES; CARRIER PROTEINS; CYSTEINE; ESCHERICHIA COLI; GENES, REPORTER; HISTIDINE; LIGANDS; MALTOSE; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SIGNAL TRANSDUCTION; SOFTWARE; SPECTROMETRY, FLUORESCENCE;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 13244281560     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1110/ps.041146005     Document Type: Article

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