Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma

Journal of Experimental Medicine

Volumn 191, Issue 3, 2000, Pages 445-453

  Yang, Tong Yuan ^a   Chen, Shu Cheng ^a   Leach, Michael W ^a   Manfra, Denise ^a   Homey, Bernhard ^a   Wiekowski, Maria ^a   Sullivan, Lee ^a   Jenh, Chung Her ^a   Narula, Satwant K ^a   Chensue, Stephen W ^b   Lira, Sergio A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Angiogenesis; Animal model; ORF74; VEGF; Viral pathogenesis

Indexed keywords

CD34 ANTIGEN; CHEMOKINE RECEPTOR; G PROTEIN COUPLED RECEPTOR; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BONE MARROW TRANSPLANTATION; DISEASE ASSOCIATION; HUMAN HERPESVIRUS 8; IMMUNOHISTOCHEMISTRY; KAPOSI SARCOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; VIRUS PATHOGENESIS;

ANIMALS; ANTIGENS, CD2; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; HEART NEOPLASMS; HEMATOPOIETIC STEM CELLS; HERPESVIRUS 8, HUMAN; LYMPHOKINES; MICE; MICE, TRANSGENIC; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, CHEMOKINE; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SARCOMA, KAPOSI; SKIN NEOPLASMS; TUMOR VIRUS INFECTIONS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS; VIRAL PROTEINS;

EID: 0034614888     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.3.445     Document Type: Article

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