Distinct functions of IRF-3 and IRF-7 in IFN-alpha gene regulation and control of anti-tumor activity in primary macrophages

Biochemical Pharmacology

Volumn 72, Issue 11, 2006, Pages 1469-1476

  Solis, Mayra ^a   Goubau, Delphine ^a   Romieu Mourez, Raphaëlle ^a   Genin, Pierre ^b   Civas, Ahmet ^b   Hiscott, John ^a  

^a MCGILL UNIVERSITY   (Canada)

^b CNRS   (France)

Author keywords

Anti tumor activity; IRF 3; IRF 7; Macrophages; Type I IFN

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; INTERFERON REGULATORY FACTOR 7; RECOMBINANT ALPHA INTERFERON; RECOMBINANT CYTOKINE; RECOMBINANT INTERFERON REGULATORY FACTOR 3; RECOMBINANT INTERFERON REGULATORY FACTOR 7; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; APOPTOSIS; ARTICLE; CELL KILLING; CELL PROLIFERATION; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; MACROPHAGE; MACROPHAGE ACTIVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; TUMOR CELL; VIRUS REPLICATION;

ANIMALS; ANTINEOPLASTIC AGENTS; CYTOTOXICITY, IMMUNOLOGIC; GENE EXPRESSION REGULATION, VIRAL; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON REGULATORY FACTOR-7; INTERFERON-ALPHA; MACROPHAGES; MICE; TRANSDUCTION, GENETIC;

EID: 33750527563     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2006.06.002     Document Type: Article

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