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Volumn 4, Issue 5, 2000, Pages 561-580

New ABC transporters in multi-drug resistance

Author keywords

ABC transporters; drug resistance; MDR

Indexed keywords


EID: 33750430768     PISSN: 14728222     EISSN: 17447631     Source Type: Journal    
DOI: 10.1517/14728222.4.5.561     Document Type: Review
Times cited : (9)

References (133)
  • 1
    • 0015893137 scopus 로고
    • Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells
    • DANO K: Active outward transport of daunomycin in resistant Ehrlich ascites tumor cells. Biochim. Biophys. Acta (1973) 323:466-483.
    • (1973) Biochim. Biophys. Acta , vol.323 , pp. 466-483
    • Dano, K.1
  • 2
    • 0018770071 scopus 로고
    • Altered surface membrane glycoproteins in vinca alkaloid-resistant human leukemic lymphoblasts
    • BECK WT, MUELLER TJ, TANZER LR: Altered surface membrane glycoproteins in vinca alkaloid-resistant human leukemic lymphoblasts. Cancer Res. (1979) 39:2070-2076.
    • (1979) Cancer Res. , vol.39 , pp. 2070-2076
    • Beck, W.T.1    Mueller, T.J.2    Tanzer, L.R.3
  • 3
    • 0014767029 scopus 로고
    • Cellular resistance to actinomy-cin D in Chinese hamster cells in vitro: Cross-resistance, radioautographic and cytogenetic studies
    • BIEDLER JL RIEHM H: Cellular resistance to actinomy-cin D in Chinese hamster cells in vitro: cross-resistance, radioautographic and cytogenetic studies. Cancer Res. (1970) 30:1174-1184.
    • (1970) Cancer Res. , vol.30 , pp. 1174-1184
    • Biedler, J.L.1    Riehm, H.2
  • 4
    • 0020578356 scopus 로고
    • Cell surface P-glycoprotein associated with multidrugresistance in mammalian cell lines
    • KARTNER N, RIORDAN JR, LING V: Cell surface P-glycoprotein associated with multidrugresistance in mammalian cell lines. Science (1983) 221:1285-1288.
    • (1983) Science , vol.221 , pp. 1285-1288
    • Kartner, N.1    Riordan, J.R.2    Ling, V.3
  • 5
    • 0029954843 scopus 로고    scopus 로고
    • P-glycoprotein-a mediator of multidrug resistance in tumour cells
    • GERMANN UA: P-glycoprotein-a mediator of multidrug resistance in tumour cells. Eur. J. Cancer (1996) 32A:927-944.
    • (1996) Eur. J. Cancer , vol.32 A , pp. 927-944
    • Germann, U.A.1
  • 6
    • 0028914111 scopus 로고
    • Characterization and functional reconsti-tution of the multidrug transporter
    • SHAROM FJ: Characterization and functional reconsti-tution of the multidrug transporter. J. Bioenerg. Biomembr. (1995) 27:15-22.
    • (1995) J. Bioenerg. Biomembr. , vol.27 , pp. 15-22
    • Sharom, F.J.1
  • 7
    • 0019430432 scopus 로고
    • Overcoming of vincristine resistance in P388 leukemia in vivoand in vitro through enhancing cytotoxicity of vincristine and vinblastine by verapamil
    • TSURUO T, IIDA H, TSUKAGOSHI S etal: Overcoming of vincristine resistance in P388 leukemia in vivoand in vitro through enhancing cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res. (1981) 41:1967-1972.
    • (1981) Cancer Res. , vol.41 , pp. 1967-1972
    • Tsuruo, T.1    Iida, H.2    Tsukagoshi, S.3
  • 8
    • 0031764330 scopus 로고    scopus 로고
    • Clinical relevance of transmembrane drug efflux as a mechanism of multidrugresistance.J
    • BRADSHAW DM, ARCECI RJ: Clinical relevance of transmembrane drug efflux as a mechanism of multidrugresistance.J. Clin. Oncol. (1998) 16:3674-90.
    • (1998) Clin. Oncol. , vol.16 , pp. 3674-90
    • Bradshaw, D.M.1    Arceci, R.J.2
  • 9
    • 0030001001 scopus 로고    scopus 로고
    • Clinical trials of P-glycoprotein reversal in solid tumours
    • FERRY DR, TRAUNECKER H, KERR DJ: Clinical trials of P-glycoprotein reversal in solid tumours. Eur. J. Cancer (1996) 32A: 1070-81.
    • (1996) Eur. J. Cancer , vol.32 A , pp. 1070-81
    • Ferry, D.R.1    Traunecker, H.2    Kerr, D.J.3
  • 11
    • 0026621245 scopus 로고
    • ABC transporters: From microorganisms to man
    • HIGGINS CF: ABC transporters: from microorganisms to man. Ann. Rev. Cell. Biol. (1992) 8:67-113.
    • (1992) Ann. Rev. Cell. Biol. , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 12
    • 0029164287 scopus 로고
    • The ABC of channel regulation
    • HIGGINS CF: The ABC of channel regulation. Cell (1995) 82:693-696.
    • (1995) Cell , vol.82 , pp. 693-696
    • Higgins, C.F.1
  • 13
    • 0023991287 scopus 로고
    • A family of closely related ATP-binding subunits from prokaryotic and eukaryotic cells
    • HIGGINS CF, GALLAGHER MP, MIMMACK ML, PEARCE SR: A family of closely related ATP-binding subunits from prokaryotic and eukaryotic cells. Bioessays (1988) 8:111-116.
    • (1988) Bioessays , vol.8 , pp. 111-116
    • Higgins, C.F.1    Gallagher, M.P.2    Mimmack, M.L.3    Pearce, S.R.4
  • 15
    • 0029820166 scopus 로고    scopus 로고
    • Characterization of the human ABC superfamily: Isolation and mapping of 21 new genes using the expressed sequence tags database
    • ALLIKMETS R, GERRARD B, HUTCHINSON A, DEAN M: Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. Hum. Mol. Genet (1996) 5:1649-1655.
    • (1996) Hum. Mol. Genet , vol.5 , pp. 1649-1655
    • Allikmets, R.1    Gerrard, B.2    Hutchinson, A.3    Dean, M.4
  • 16
    • 0034652629 scopus 로고    scopus 로고
    • Identification of 18 mouse ABC genes and characterization of the ABC superfamily in mus musculus
    • SCHRIML LM, DEAN M: Identification of 18 mouse ABC genes and characterization of the ABC superfamily in mus musculus. Genomics (2000) 64:24-31.
    • (2000) Genomics , vol.64 , pp. 24-31
    • Schriml, L.M.1    Dean, M.2
  • 17
    • 0030738677 scopus 로고    scopus 로고
    • Multidrug resistance: Molecular mechanisms and clinical relevance
    • LING V: Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother. Pharmacol. (1997) 40(Suppl.):S3-S8.
    • (1997) Cancer Chemother. Pharmacol. , vol.40 , Issue.SUPPL.
    • Ling, V.1
  • 19
    • 0001223675 scopus 로고    scopus 로고
    • Future perspectives for the development of P-glycoprotein modulators
    • SANDOR V, FOJO T, BATES SE: Future perspectives for the development of P-glycoprotein modulators. Drug Resist. Updates (1998) 1:190-200.
    • (1998) Drug Resist. Updates , vol.1 , pp. 190-200
    • Sandor, V.1    Fojo, T.2    Bates, S.E.3
  • 20
    • 0029974821 scopus 로고    scopus 로고
    • Pharmacological considerations in the modulation of multidrug resistance
    • FISHER GA, LUM BL, HAUSDORFF J, SIKIC BI: Pharmacological considerations in the modulation of multidrug resistance. Eur. J. Cancer (1996) 32A:1082-1088.
    • (1996) Eur. J. Cancer , vol.32 A , pp. 1082-1088
    • Fisher, G.A.1    Lum, B.L.2    Hausdorff, J.3    Sikic, B.I.4
  • 21
    • 0030666026 scopus 로고    scopus 로고
    • A dose-finding and pharmacokinetic study of reversal of multidrug resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumors
    • GIACCONE G, LINN SC, WELINK J et al: A dose-finding and pharmacokinetic study of reversal of multidrug resistance with SDZ PSC 833 in combination with doxorubicin in patients with solid tumors. Clin. Cancer Res. (1997) 3:2005-2015.
    • (1997) Clin. Cancer Res. , vol.3 , pp. 2005-2015
    • Giaccone, G.1    Linn, S.C.2    Welink, J.3
  • 22
    • 0033993578 scopus 로고    scopus 로고
    • FEARS CA etal: Phase i study of paclitaxel in combination with a multidrug resistance modulator, PSC 833 (Valspodar), in refractory malignancies
    • FRACASSO PM, WESTERVELDT P, FEARS CA etal: Phase I study of paclitaxel in combination with a multidrug resistance modulator, PSC 833 (Valspodar), in refractory malignancies.J. Clin. Oncol. (2000) 18:1124.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1124
    • Fracasso, P.M.1    Westerveldt, P.2
  • 23
    • 18844482235 scopus 로고    scopus 로고
    • A Phase i study of induction chemotherapy for older patients with newly diagnosed acute myeloid leukemia (AML) using mitoxantrone, etoposide and the MDR modulator PSC 833: A Southwest Oncology Group study 9617
    • CHAUNCEYTR, RANKIN C, ANDERSON JE etal: A Phase I study of induction chemotherapy for older patients with newly diagnosed acute myeloid leukemia (AML) using mitoxantrone, etoposide and the MDR modulator PSC 833: a Southwest Oncology Group study 9617. Leuk. Res. (2000) 24:567-574.
    • (2000) Leuk. Res. , vol.24 , pp. 567-574
    • Chaunceytr Rankin, C.1    Anderson, J.E.2
  • 24
    • 0031686969 scopus 로고    scopus 로고
    • Phase i and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP
    • ROWINSKY EK, SMITH L, WANG YM et al: Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP. J. Clin. Oncol. (1998) 16:2964-2976.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2964-2976
    • Rowinsky, E.K.1    Smith, L.2    Wang, Y.M.3
  • 25
    • 0033390989 scopus 로고    scopus 로고
    • JEWELL RC etal: Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein
    • SPARREBOOM A, PLANTING AS, JEWELL RC etal: Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein. AntiCancer Drugs (1999) 10:719-728.
    • (1999) AntiCancer Drugs , vol.10 , pp. 719-728
    • Sparreboom, A.1    Planting, A.S.2
  • 26
    • 0032763895 scopus 로고    scopus 로고
    • Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities
    • DANTZIG AH, SHEPARD RL, LAW KL et al: Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities. J. Pharmacol. Exp. Ther. (1999) 290:854-862.
    • (1999) J. Pharmacol. Exp. Ther. , vol.290 , pp. 854-862
    • Dantzig, A.H.1    Shepard, R.L.2    Law, K.L.3
  • 27
    • 0032881342 scopus 로고    scopus 로고
    • The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein
    • MARTIN C, BERRIDGE G, MISTRY P et al: The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein. Br. J. Pharmacol. (1999) 128:403-411.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 403-411
    • Martin, C.1    Berridge, G.2    Mistry, P.3
  • 28
    • 80052078357 scopus 로고    scopus 로고
    • ROMANO SJ etal: Preclinical characterization and clinical safety/pharmacokinetics of OC144-093, a novel inhibitor of p-glycoprotein- mediated multidrug resistance
    • NEWMAN MJ, RODARTE JC, ROMANO SJ etal: Preclinical characterization and clinical safety/pharmacokinetics of OC144-093, a novel inhibitor of p-glycoprotein-mediated multidrug resistance. Proc. Amer Assoc. Cancer Res. (1999) 40.
    • (1999) Proc. Amer Assoc. Cancer Res. , vol.40
    • Newman, M.J.1    Rodarte, J.C.2
  • 29
    • 7844251179 scopus 로고    scopus 로고
    • Ventricular arrhythmia and Torsade de Pointe: Dose limiting toxicities of the MDR-modulator S9788 in a Phase i trial
    • STUPP R, BAUER J, PAGANI O et al.: Ventricular arrhythmia and Torsade de Pointe: dose limiting toxicities of the MDR-modulator S9788 in a Phase I trial. Ann. Oncol (1998) 9:1233-1242.
    • (1998) Ann. Oncol , vol.9 , pp. 1233-1242
    • Stupp, R.1    Bauer, J.2    Pagani, O.3
  • 30
    • 0034006531 scopus 로고    scopus 로고
    • The orally administered P-glycoprotein inhibitor R101933 does not alter the plasma pharmacokinetics of docetaxel
    • VAN ZUYLEN L, SPARREBOOM A, VAN DER GAAST A etal: The orally administered P-glycoprotein inhibitor R101933 does not alter the plasma pharmacokinetics of docetaxel. Clin. Cancer Res. (2000) 6:1365-1371.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1365-1371
    • Van Zuylen, L.1    Sparreboom, A.2    Van Der Gaast, A.3
  • 31
    • 0027095653 scopus 로고
    • Overex-pression of a transporter gene in a multidrug-resistant human lung cancer cell line
    • COLE SPC, BHARDWAJ G, GERLACH JH et al: Overex-pression of a transporter gene in a multidrug-resistant human lung cancer cell line. Science (1992) 258:1650-1654.
    • (1992) Science , vol.258 , pp. 1650-1654
    • Spc, C.1    Bhardwaj, G.2    Gerlach, J.H.3
  • 32
    • 0033610801 scopus 로고    scopus 로고
    • Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain
    • BAKOS E, EVERS R, SZAKACS G et al: Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain. J. Biol. Chem. (1998) 273:32167-32175.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32167-32175
    • Bakos, E.1    Evers, R.2    Szakacs, G.3
  • 33
    • 0030450845 scopus 로고    scopus 로고
    • Double knockout of the MRP gene leads to increased drug sensitivity invitro
    • LORICO A, RAPPA G, FLAVELL RA, SARTORELLI AC: Double knockout of the MRP gene leads to increased drug sensitivity invitro. CancerRes. (1996) 56:5351-5355.
    • (1996) CancerRes. , vol.56 , pp. 5351-5355
    • Lorico, A.1    Rappa, G.2    Flavell, R.A.3    Sartorelli, A.C.4
  • 34
    • 0028001416 scopus 로고
    • ATP-dependent transport of glutathion S-conjugates by multidrug resistance-associated protein
    • JEDLITSCHKY G, LEIER I, BUCHHOLZ U, CENTER M, KEPPLER D: ATP-dependent transport of glutathion S-conjugates by multidrug resistance-associated protein. Cancer Res. (1994) 54:4833-4836.
    • (1994) Cancer Res. , vol.54 , pp. 4833-4836
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Center, M.4    Keppler, D.5
  • 35
    • 0030063480 scopus 로고    scopus 로고
    • Transport of glutathione, glucuronate and sulfate conjugates by the MRP gene-encoded conjugate exportpump
    • JEDLITSCHKY G, LEIER I, BUCHHOLZ U etal: Transport of glutathione, glucuronate and sulfate conjugates by the MRP gene-encoded conjugate exportpump. Cancer Res. (1996) 56:988-994.
    • (1996) Cancer Res. , vol.56 , pp. 988-994
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3
  • 36
    • 0032946239 scopus 로고    scopus 로고
    • ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P
    • CHEN ZS, FURUKAWA T, SUMIZAWA T et al.: ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P. Mol. Pharmacol. (1999) 55:921-928.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 921-928
    • Chen, Z.S.1    Furukawa, T.2    Sumizawa, T.3
  • 37
    • 0033152212 scopus 로고    scopus 로고
    • KOOL M etal: Antifo-late resistance mediated by the multidrug resistance proteins MRP1 and MRP2
    • HOOIJBERG JH, BROXTERMAN HJ, KOOL M etal: Antifo-late resistance mediated by the multidrug resistance proteins MRP1 and MRP2. Cancer Res. (1999) 59:2532-2535.
    • (1999) Cancer Res. , vol.59 , pp. 2532-2535
    • Hooijberg, J.H.1    Broxterman, H.J.2
  • 38
    • 0032534064 scopus 로고    scopus 로고
    • Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): Evidence for cotransport with reduced glutathione
    • LOE DW, DEELEY RG, COLE SP: Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione. Cancer Res. (1998) 58:5130-5136.
    • (1998) Cancer Res. , vol.58 , pp. 5130-5136
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 39
  • 40
    • 0034674901 scopus 로고    scopus 로고
    • A family of drug transporters: The multidrug resistance-associated proteins
    • BORST P, EVERS R, KOOL M, WIJNHOLDS J: A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst. (2000) 92:1295-1302.
    • (2000) J. Natl. Cancer Inst. , vol.92 , pp. 1295-1302
    • Borst, P.1    Evers, R.2    Kool, M.3    Wijnholds, J.4
  • 41
    • 0030678131 scopus 로고    scopus 로고
    • Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins
    • RAPPA G, LORICO A, FLAVELL RA, SARTORELLI AC: Evidence that the multidrug resistance protein (MRP) functions as a co-transporter of glutathione and natural product toxins. CancerRes. (1997) 57:5232-5237.
    • (1997) CancerRes. , vol.57 , pp. 5232-5237
    • Rappa, G.1    Lorico, A.2    Flavell, R.A.3    Sartorelli, A.C.4
  • 42
    • 0028825399 scopus 로고
    • Absence of the MDR1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin and cyclosporin A.J
    • SCHINKEL AH, WAGENAAR E, VAN DEEMTER L, MOL CA, BORST P: Absence of the MDR1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin and cyclosporin A.J. Clin. Invest. (1995) 96:1698-1705.
    • (1995) Clin. Invest. , vol.96 , pp. 1698-1705
    • Schinkel, A.H.1    Wagenaar, E.2    Van Deemter, L.3    Mol, C.A.4    Borst, P.5
  • 43
    • 0000712439 scopus 로고
    • Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
    • CORDON-CARDO C, O'BRIEN JP, CASALS D et al.: Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc. Natl. Acad. Sci. USA (1989) 86:695-698.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 695-698
    • Cordon-Cardo, C.1    O'Brien, J.P.2    Casals, D.3
  • 44
    • 0030823912 scopus 로고    scopus 로고
    • P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain
    • BEAULIEU E, DEMEULE M, GHITESCU L, BELIVEAU R: P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain. Biochem. J. (1997) 326 (Pt 2): 539-44.
    • (1997) Biochem. J. , vol.326 , Issue.PART 2 , pp. 539-544
    • Beaulieu, E.1    Demeule, M.2    Ghitescu, L.3    Beliveau, R.4
  • 45
    • 0029981430 scopus 로고    scopus 로고
    • Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene
    • PAULUSMA CC, BOSMA PJ, ZAMAN GJR et al: Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. Science (1996) 271:1126-1128.
    • (1996) Science , vol.271 , pp. 1126-1128
    • Paulusma, C.C.1    Bosma, P.J.2    Gjr, Z.3
  • 46
    • 0033526176 scopus 로고    scopus 로고
    • P-Glycoprotein, a gatekeeper in the blood-brain barrier
    • SCHINKEL AH: P-Glycoprotein, a gatekeeper in the blood-brain barrier. Adv. Drug Deliv. Rev. (1999) 36:179-194.
    • (1999) Adv. Drug Deliv. Rev. , vol.36 , pp. 179-194
    • Schinkel, A.H.1
  • 47
    • 0032960014 scopus 로고    scopus 로고
    • Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline a peripherally acting analgaesic drug
    • JONKERJW, WAGENAAR E, VAN DEEMTER Let al: Role of blood-brain barrier P-glycoprotein in limiting brain accumulation and sedative side-effects of asimadoline, a peripherally acting analgaesic drug. Br J. Pharmacol (1999) 127:43-50.
    • (1999) Br J. Pharmacol , vol.127 , pp. 43-50
    • Jonker, J.W.1    Wagenaar, E.2    Van Deemter, L.3
  • 48
    • 20244386956 scopus 로고    scopus 로고
    • Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
    • WIJNHOLDS J, EVERS R, VAN LEUSDEN MR et al.: Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein. Nature Med. (1997) 3:1275-1279.
    • (1997) Nature Med. , vol.3 , pp. 1275-1279
    • Wijnholds, J.1    Evers, R.2    Van Leusden, M.R.3
  • 49
    • 0030665969 scopus 로고    scopus 로고
    • FINCH RA etal: Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
    • LORICO A, RAPPA G, FINCH RA etal: Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione. Cancer Res. (1997) 57:5238-5242.
    • (1997) Cancer Res. , vol.57 , pp. 5238-5242
    • Lorico, A.1    Rappa, G.2
  • 50
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT(MRP2), MRP3, MRP4 and MRP5, homologues of the multidrug resistance-associated protein gene in human cancer cell lines
    • KOOL M, DE HAAS M, SCHEFFER GL et al: Analysis of expression of cMOAT(MRP2), MRP3, MRP4 and MRP5, homologues of the multidrug resistance-associated protein gene in human cancer cell lines. Cancer Res. (1997) 57:3537-3547.
    • (1997) Cancer Res. , vol.57 , pp. 3537-3547
    • Kool, M.1    De Haas, M.2    Scheffer, G.L.3
  • 51
    • 0033020785 scopus 로고    scopus 로고
    • MOAT-E(ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
    • BELINSKY MG, KRUH GD: MOAT-E(ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver. Br J. Cancer (1999) 80:1342-1349.
    • (1999) Br J. Cancer , vol.80 , pp. 1342-1349
    • Belinsky, M.G.1    Kruh, G.D.2
  • 52
    • 0032545019 scopus 로고    scopus 로고
    • Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins
    • BELINSKY MG, BAIN LJ, BALSARA BB, TESTA JR, KRUH GD: Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins. J. Natl. Cancer Inst. (1998) 90:1735-1741.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 1735-1741
    • Belinsky, M.G.1    Bain, L.J.2    Balsara, B.B.3    Testa, J.R.4    Kruh, G.D.5
  • 53
    • 0040761368 scopus 로고    scopus 로고
    • CDNAcloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats
    • BUCHLER M, KONIG J, BROM M etal: cDNAcloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats. J. Biol. Chem. (1996) 271:15091-15098.
    • (1996) J. Biol. Chem. , vol.271 , pp. 15091-15098
    • Buchler, M.1    Konig, J.2    Brom, M.3
  • 54
    • 0033361943 scopus 로고    scopus 로고
    • Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome
    • TOH S, WADA M, UCHIUMI T etal: Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome. Am. J. Hum. Genet. (1999) 64:739-746.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 739-746
    • Toh, S.1    Wada, M.2    Uchiumi, T.3
  • 55
    • 0033032730 scopus 로고    scopus 로고
    • Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma
    • SCHAUB TP, KARTENBECK J, KONIG J et al.: Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma. J. Am. Soc. Nephrol. (1999) 10:1159-1169.
    • (1999) J. Am. Soc. Nephrol. , vol.10 , pp. 1159-1169
    • Schaub, T.P.1    Kartenbeck, J.2    Konig, J.3
  • 56
    • 0027960078 scopus 로고
    • Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells
    • COLE SPC, SPARKS KE, FRASER K et al.: Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells. Cancer Res. (1994) 54:5902-5910.
    • (1994) Cancer Res. , vol.54 , pp. 5902-5910
    • Spc, C.1    Sparks, K.E.2    Fraser, K.3
  • 57
    • 0031468814 scopus 로고    scopus 로고
    • A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells
    • KOIKE K, KAWABE T, TANAKA T et al.: A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells. Cancer Res. (1997) 57:5475-5479.
    • (1997) Cancer Res. , vol.57 , pp. 5475-5479
    • Koike, K.1    Kawabe, T.2    Tanaka, T.3
  • 58
    • 0345299165 scopus 로고    scopus 로고
    • Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells
    • CUI Y, KONIG J, BUCHHOLZ JK et al.: Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells. Mol. Pharmacol. (1999) 55:929-937.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 929-937
    • Cui, Y.1    Konig, J.2    Buchholz, J.K.3
  • 59
    • 0030753176 scopus 로고    scopus 로고
    • Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats
    • MASUDA M, I'IZUKA Y, YAMAZAKI Met al.: Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats. Cancer Res. (1997) 57:3506-3510.
    • (1997) Cancer Res. , vol.57 , pp. 3506-3510
    • Masuda, M.1    I'Izuka, Y.2    Yamazaki, M.3
  • 60
    • 9544233652 scopus 로고    scopus 로고
    • A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation
    • TANIGUCHI K, WADA M, KOHNO K et al.: A human canalicular multispecific organic anion transporter (cMOAT) gene is overexpressed in cisplatin-resistant human cancer cell lines with decreased drug accumulation. Cancer Res. (1996) 56:4124-4129.
    • (1996) Cancer Res. , vol.56 , pp. 4124-4129
    • Taniguchi, K.1    Wada, M.2    Kohno, K.3
  • 61
    • 0033407050 scopus 로고    scopus 로고
    • Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents
    • ZENG H, BAIN LJ, BELINSKY MG, KRUH GD: Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents. Cancer Res. (1999) 59:5964-5967.
    • (1999) Cancer Res. , vol.59 , pp. 5964-5967
    • Zeng, H.1    Bain, L.J.2    Belinsky, M.G.3    Kruh, G.D.4
  • 62
    • 13044294031 scopus 로고    scopus 로고
    • MRP3,an organic anion transporter able to transport anti-cancer drugs
    • KOOL M,VAN DER LINDENM,DE HAAS Met al.:MRP3,an organic anion transporter able to transport anti-cancer drugs. Proc. Natl. Acad. Sci. USA (1999) 96:6914-6919.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6914-6919
    • Kool, M.1    Van Der Lindenm2    De Haas, M.3
  • 63
    • 0033066688 scopus 로고    scopus 로고
    • MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte
    • ORTIZ DF, LI S, IYER R et al.: MRP3, a new ATP-binding cassette protein localized to the canalicular domain of the hepatocyte. Am. J. Physiol. (1999) 276:G1493-500.
    • (1999) Am. J. Physiol. , vol.276
    • Ortiz, D.F.1    S, L.I.2    Iyer, R.3
  • 64
    • 0032926354 scopus 로고    scopus 로고
    • Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane
    • KONIGJ,ROSTD, CUI Y, KEPPLERD: Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology (1999) 29:1156-1163.
    • (1999) Hepatology , vol.29 , pp. 1156-1163
    • Konigjrostd1    Cui, Y.2    Kepplerd3
  • 65
    • 0033551671 scopus 로고    scopus 로고
    • PABC11(alsoknownasMOAT-CandMRP5),amember of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells
    • MCALEER MA, BREEN MA, WHITE NL, MATTHEWS N: pABC11(alsoknownasMOAT- CandMRP5),amember of the ABC family of proteins, has anion transporter activity but does not confer multidrug resistance when overexpressed in human embryonic kidney 293 cells. J. Biol. Chem. (1999) 274:23541-23548.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23541-23548
    • McAleer, M.A.1    Breen, M.A.2    White, N.L.3    Matthews, N.4
  • 66
    • 0029022589 scopus 로고
    • Identification of a sister gene to P-glycoprotein
    • CHILDS S, YEH RL, GEORGES E, LING V: Identification of a sister gene to P-glycoprotein. Cancer Res. (1995) 55:2029-2034.
    • (1995) Cancer Res. , vol.55 , pp. 2029-2034
    • Childs, S.1    Yeh, R.L.2    Georges, E.3    Ling, V.4
  • 67
    • 0032540277 scopus 로고    scopus 로고
    • The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
    • GERLOFF T, STIEGER B, HAGENBUCH B et al.: The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J. Biol. Chem. (1998) 273:10046-10050.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10046-10050
    • Gerloff, T.1    Stieger, B.2    Hagenbuch, B.3
  • 68
    • 0032530533 scopus 로고    scopus 로고
    • Taxol resistance mediated by transfection of the liver-specific sister geneofP-glycoprotein
    • CHILDS S, YEH RL, HUI D, LING V: Taxol resistance mediated by transfection of the liver-specific sister geneofP-glycoprotein. Cancer Res.(1998) 58:4160-4167.
    • (1998) Cancer Res. , vol.58 , pp. 4160-4167
    • Childs, S.1    Yeh, R.L.2    Hui, D.3    Ling, V.4
  • 69
    • 0033989134 scopus 로고    scopus 로고
    • Cloning and expressionofmurine sisterofP-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein
    • LECUREUR V, SUN D, HARGROVE P et al.: Cloning and expressionofmurine sisterofP-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. Mol. Pharmacol. (2000) 57:24-35.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 24-35
    • Lecureur, V.1    Sun, D.2    Hargrove, P.3
  • 70
    • 0032054730 scopus 로고    scopus 로고
    • Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells
    • LAING NM, BELINSKY MG, KRUH GDetal.: Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells. Cancer Res. (1998) 58:1332-1337.
    • (1998) Cancer Res. , vol.58 , pp. 1332-1337
    • Laing, N.M.1    Belinsky, M.G.2    Kruh, G.D.3
  • 72
    • 0033569840 scopus 로고    scopus 로고
    • The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression
    • BERGER J, ALBET S, BENTEJAC M et al.: The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression. Eur. J. Biochem. (1999) 265:719-727.
    • (1999) Eur. J. Biochem. , vol.265 , pp. 719-727
    • Berger, J.1    Albet, S.2    Bentejac, M.3
  • 73
    • 0027532282 scopus 로고
    • Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters
    • MOSSER J, DOUAR AM, SARDE CO et al.: Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters. Nature (1993) 361:726-730.
    • (1993) Nature , vol.361 , pp. 726-730
    • Mosser, J.1    Douar, A.M.2    Sarde, C.O.3
  • 74
    • 0028962332 scopus 로고
    • Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts
    • CARTIER N, LOPEZ J, MOULLIER P et al.: Retroviral-mediated gene transfer corrects very-long-chain fatty acid metabolism in adrenoleukodystrophy fibroblasts. Proc. Natl. Acad. Sci. USA (1995) 92:1674-1678.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1674-1678
    • Cartier, N.1    Lopez, J.2    Moullier, P.3
  • 75
    • 0029087359 scopus 로고
    • Adreno-leukodystrophy: The restoration of peroxisomal beta-oxidation by transfection of normal cDNA
    • SHINNOH N, YAMADA T, YOSHIMURA T et al.: Adreno-leukodystrophy: the restoration of peroxisomal beta-oxidation by transfection of normal cDNA. Biochem. Biophys. Res. Commun. (1995) 210:830-836.
    • (1995) Biochem. Biophys. Res. Commun. , vol.210 , pp. 830-836
    • Shinnoh, N.1    Yamada, T.2    Yoshimura, T.3
  • 76
    • 0000470358 scopus 로고    scopus 로고
    • Homo-and heterodimerization of peroxisomal ATP-binding cassette half-transporters
    • LIU LX, JANVIER K, BERTEAUX-LECELLIER V et al.: Homo-and heterodimerization of peroxisomal ATP-binding cassette half-transporters. J. Biol. Chem. (1999) 274:32738-32743.
    • (1999) J. Biol. Chem. , vol.274 , pp. 32738-32743
    • Liu, L.X.1    Janvier, K.2    Berteaux-Lecellier, V.3
  • 77
    • 0032924991 scopus 로고    scopus 로고
    • Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): Implications for therapy
    • NETIK A, FORSS-PETTER S, HOLZINGER A et al.: Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy. Hum. Mol. Genet. (1999) 8:907-913.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 907-913
    • Netik, A.1    Forss-Petter, S.2    Holzinger, A.3
  • 78
    • 0032721515 scopus 로고    scopus 로고
    • Function of the transport complex TAP in cellular immune recognition
    • ABELE R, TAMPE R: Function of the transport complex TAP in cellular immune recognition. Biochim. Biophys. Acta (1999) 1461:405-419.
    • (1999) Biochim. Biophys. Acta , vol.1461 , pp. 405-419
    • Abele, R.1    Tampe, R.2
  • 79
    • 0026342850 scopus 로고
    • Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter
    • POWIS SJ, TOWNSEND AR, DEVERSON EV et al.: Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter. Nature (1991) 354:528-531.
    • (1991) Nature , vol.354 , pp. 528-531
    • Powis, S.J.1    Townsend, A.R.2    Deverson, E.V.3
  • 80
    • 0028147121 scopus 로고
    • Homozygous human TAP peptide transporter mutation inHLA class i deficiency
    • DE LA SALLEH,HANAU D, FRICKER Det al.: Homozygous human TAP peptide transporter mutation inHLA class I deficiency. Science (1994) 265 : 237-41.
    • (1994) Science , vol.265 , pp. 237-41
    • De La Salle, H.H.1    Anau, D.2    Fricker, D.3
  • 81
    • 0030841049 scopus 로고    scopus 로고
    • A case of primary immunodeficiency due to a defect of the major histocompatibility gene complex class i processing and presentation pathway
    • TEISSERENC H, SCHMITT W, BLAKE N et al.: A case of primary immunodeficiency due to a defect of the major histocompatibility gene complex class I processing and presentation pathway. Immunol. Lett. (1997) 57:183-187.
    • (1997) Immunol. Lett. , vol.57 , pp. 183-187
    • Teisserenc, H.1    Schmitt, W.2    Blake, N.3
  • 82
    • 0033105718 scopus 로고    scopus 로고
    • Splice acceptor site mutation of the transporter associated with antigen processing-1 gene in human bare lymphocyte syndrome
    • FURUKAWA H, MURATA S, YABE T et al.: Splice acceptor site mutation of the transporter associated with antigen processing-1 gene in human bare lymphocyte syndrome. J. Clin. Invest. (1999) 103:755-758.
    • (1999) J. Clin. Invest. , vol.103 , pp. 755-758
    • Furukawa, H.1    Murata, S.2    Yabe, T.3
  • 83
    • 0033104718 scopus 로고    scopus 로고
    • HLA class i deficiencies due to mutations in subunit 1 of the peptide transporter TAP1
    • DE LA SALLE H, ZIMMER J, FRICKER D et al.: HLA class I deficiencies due to mutations in subunit 1 of the peptide transporter TAP1. J. Clin. Invest. (1999) 103:R9-R13.
    • (1999) J. Clin. Invest. , vol.103
    • De La Salle, H.1    Zimmer, J.2    Fricker, D.3
  • 84
    • 0029789436 scopus 로고    scopus 로고
    • A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity
    • ARMANDOLA EA, MOMBURG F, NIJENHUIS M et al.: A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity. Eur. J. Immunol. (1996) 26:1748-1755.
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1748-1755
    • Armandola, E.A.1    Momburg, F.2    Nijenhuis, M.3
  • 85
    • 0030023563 scopus 로고    scopus 로고
    • Residues in TAP2 peptide transporters controlling substrate specificity
    • MOMBURG F, ARMANDOLA EA, POST M, HAMMERLING GJ: Residues in TAP2 peptide transporters controlling substrate specificity. J. Immunol. (1996) 156:1756-1763.
    • (1996) J. Immunol. , vol.156 , pp. 1756-1763
    • Momburg, F.1    Armandola, E.A.2    Post, M.3    Hammerling, G.J.4
  • 86
    • 0032920837 scopus 로고    scopus 로고
    • Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)
    • ALLIKMETS R, RASKIND WH, HUTCHINSON A et al.: Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A). Hum. Mol. Genet. (1999) 8:743-749.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 743-749
    • Allikmets, R.1    Raskind, W.H.2    Hutchinson, A.3
  • 87
    • 0032414310 scopus 로고    scopus 로고
    • Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p
    • CSERE P, LILL R, KISPAL G: Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p. FEBS Lett. (1998) 441:266-270.
    • (1998) FEBS Lett. , vol.441 , pp. 266-270
    • Csere, P.1    Lill, R.2    Kispal, G.3
  • 88
    • 0033534545 scopus 로고    scopus 로고
    • Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein
    • HOGUE DL, LIU L, LING V: Identification and characterization of a mammalian mitochondrial ATP-binding cassette membrane protein. J. Mol. Biol. (1999) 285:379-389.
    • (1999) J. Mol. Biol. , vol.285 , pp. 379-389
    • Hogue, D.L.1    Liu, L.2    Ling, V.3
  • 89
    • 0029890960 scopus 로고    scopus 로고
    • Cloning of the cDNA for a human homologue of the Drosophila whitegene and mapping to chromosome 21q22.3
    • CHEN H, ROSSIER C, LALIOTI MD et al.: Cloning of the cDNA for a human homologue of the Drosophila whitegene and mapping to chromosome 21q22.3. Am. J. Hum. Genet. (1996) 59:66-75.
    • (1996) Am. J. Hum. Genet. , vol.59 , pp. 66-75
    • Chen, H.1    Rossier, C.2    Lalioti, M.D.3
  • 90
    • 0031034963 scopus 로고    scopus 로고
    • Isolation and characterization of a mammalian homolog of the Drosophila white gene
    • CROOP JM, TILLER GE, FLETCHER JA et al.: Isolation and characterization of a mammalian homolog of the Drosophila white gene. Gene (1997) 185:77-85.
    • (1997) Gene , vol.185 , pp. 77-85
    • Croop, J.M.1    Tiller, G.E.2    Fletcher, J.A.3
  • 91
    • 0033066317 scopus 로고    scopus 로고
    • Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determineeyecoloura-tion
    • MACKENZIE SM, BROOKER MR, GILL TR et al.: Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determineeyecoloura- tion. Biochim. Biophys. Acta (1999) 1419:173-185.
    • (1999) Biochim. Biophys. Acta , vol.1419 , pp. 173-185
    • MacKenzie, S.M.1    Brooker, M.R.2    Gill, T.R.3
  • 92
    • 0028177555 scopus 로고
    • Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships
    • EWART GD, CANNELL D, COX GB, HOWELLS AJ: Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships. J. Biol. Chem. (1994) 269:10370-10377.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10370-10377
    • Ewart, G.D.1    Cannell, D.2    Cox, G.B.3    Howells, A.J.4
  • 93
    • 0034640288 scopus 로고    scopus 로고
    • Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcrip-tional role for specific oxysterols
    • VENKATESWARAN A, REPA JJ, LOBACCARO JM et al.: Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcrip-tional role for specific oxysterols. J. Biol. Chem. (2000) 275:14700-14707.
    • (2000) J. Biol. Chem. , vol.275 , pp. 14700-14707
    • Venkateswaran, A.1    Repa, J.J.2    Lobaccaro, J.M.3
  • 94
    • 0032404092 scopus 로고    scopus 로고
    • A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance
    • ALLIKMETS R, SCHRIML LM, HUTCHINSON A, ROMANO-SPICA V, DEAN M: A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res. (1998) 58:5337-5339.
    • (1998) Cancer Res. , vol.58 , pp. 5337-5339
    • Allikmets, R.1    Schriml, L.M.2    Hutchinson, A.3    Romano-Spica, V.4    Dean, M.5
  • 95
    • 13044249156 scopus 로고    scopus 로고
    • A multidrug resistance transporter from human MCF-7 breast cancer cells
    • DOYLE LA, YANG W, ABRUZZO LV et al.: A multidrug resistance transporter from human MCF-7 breast cancer cells. Proc. Natl. Acad. Sci. USA (1998) 95:15665-15670.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 15665-15670
    • Doyle, L.A.1    Yang, W.2    Abruzzo, L.V.3
  • 96
    • 0032895533 scopus 로고    scopus 로고
    • Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: Demonstration of homology to ABC transport genes
    • MIYAKE K, MICKLEY L, LITMAN T et al: Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes. Cancer Res. (1999) 59:8-13.
    • (1999) Cancer Res. , vol.59 , pp. 8-13
    • Miyake, K.1    Mickley, L.2    Litman, T.3
  • 97
    • 0344304478 scopus 로고    scopus 로고
    • Cloning and characterization of breast cancer resistance protein (BCRP), a novel ATP-binding cassette (ABC) transporter that may contribute to the multidrug-resistance phenotype of MCF-7/AdrVp breast cancer cells
    • DOYLE LA, YANG W, ABRUZZO LE et al: Cloning and characterization of breast cancer resistance protein (BCRP), a novel ATP-binding cassette (ABC) transporter that may contribute to the multidrug-resistance phenotype of MCF-7/AdrVp breast cancer cells. Proc. Amer. Assoc. Cancer Res. (1998) 39.
    • (1998) Proc. Amer. Assoc. Cancer Res. , vol.39
    • Doyle, L.A.1    Yang, W.2    Abruzzo, L.E.3
  • 98
    • 0025322402 scopus 로고
    • Charac terization of Adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein
    • CHEN Y-N, MICKLEY LA, SCHWARTZ AM et al.: Charac terization of Adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein. J. Biol. Chem. (1990) 265:10073-10080.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10073-10080
    • Chen, Y.-N.1    Mickley, L.A.2    Schwartz, A.M.3
  • 99
    • 0000776551 scopus 로고    scopus 로고
    • Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression
    • LEE JS, SCALA S, MATSUMOTO Y et al: Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression. J. Cell. Biochem. (1997) 65:513-526.
    • (1997) J. Cell. Biochem. , vol.65 , pp. 513-526
    • Lee, J.S.1    Scala, S.2    Matsumoto, Y.3
  • 100
    • 0029091756 scopus 로고
    • Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase i alterations
    • YANG C-HJ, HORTON JK, COWAN K, SCHNEIDER E: Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations. Cancer Res. (1995) 55:4004-4009.
    • (1995) Cancer Res. , vol.55 , pp. 4004-4009
    • Yang, C.-H.J.1    Horton, J.K.2    Cowan, K.3    Schneider, E.4
  • 101
    • 0025733402 scopus 로고
    • Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line
    • TAYLOR CW, DALTON WS, PARRISH PR et al: Different mechanisms of decreased drug accumulation in doxorubicin and mitoxantrone resistant variants of the MCF7 human breast cancer cell line. Br. J. Cancer (1991) 63:923-929.
    • (1991) Br. J. Cancer , vol.63 , pp. 923-929
    • Taylor, C.W.1    Dalton, W.S.2    Parrish, P.R.3
  • 102
    • 0026496549 scopus 로고
    • Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 human breast cancer cells
    • NAKAGAWA M, SCHNEIDER E, DIXON KH et al: Reduced intracellular drug accumulation in the absence of P-glycoprotein (mdr1) overexpression in mitoxantrone-resistant human MCF-7 human breast cancer cells. Cancer Res. (1992) 52:6175-6181.
    • (1992) Cancer Res. , vol.52 , pp. 6175-6181
    • Nakagawa, M.1    Schneider, E.2    Dixon, K.H.3
  • 103
    • 0023897681 scopus 로고
    • Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone
    • DALTON WS, CRESS AE, ALBERTS DS, TRENT JM: Cytogenetic and phenotypic analysis of a human colon carcinoma cell line resistant to mitoxantrone. Cancer Res. (1988) 48:1882-1888.
    • (1988) Cancer Res. , vol.48 , pp. 1882-1888
    • Dalton, W.S.1    Cress, A.E.2    Alberts, D.S.3    Trent, J.M.4
  • 104
    • 0032535004 scopus 로고    scopus 로고
    • Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C
    • RABINDRANS K, HE H, SINGH M etal: Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. (1998) 58:5850-5858.
    • (1998) Cancer Res. , vol.58 , pp. 5850-5858
    • Rabindrans, K.1    H, H.E.2    Singh, M.3
  • 105
    • 0033104367 scopus 로고    scopus 로고
    • Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line
    • HAZLEHURST LA, FOLEY NE, GLEASON-GUZMAN MC et al: Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line. Cancer Res. (1999) 59:1021-1028.
    • (1999) Cancer Res. , vol.59 , pp. 1021-1028
    • Hazlehurst, L.A.1    Foley, N.E.2    Gleason-Guzman, M.C.3
  • 106
    • 0025175599 scopus 로고
    • Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257
    • DIETEL M, ARPS H, LAGE H, NIENDORF A: Membrane vesicle formation due to acquired mitoxantrone resistance in human gastric carcinoma cell line EPG85-257. Cancer Res. (1990) 50:6100-6106.
    • (1990) Cancer Res. , vol.50 , pp. 6100-6106
    • Dietel, M.1    Arps, H.2    Lage, H.3    Niendorf, A.4
  • 107
    • 0030922194 scopus 로고    scopus 로고
    • Decreased drug accumulation in a mitoxantrone-resistant gastric carcinoma cell line in the absence of P-glycoprotein
    • KELLNER U, HUTCHINSON L, SEIDEL A etal: Decreased drug accumulation in a mitoxantrone-resistant gastric carcinoma cell line in the absence of P-glycoprotein. Int. J. Cancer (1997) 71:817-824.
    • (1997) Int. J. Cancer , vol.71 , pp. 817-824
    • Kellner, U.1    Hutchinson, L.2    Seidel, A.3
  • 108
    • 0033518874 scopus 로고    scopus 로고
    • Atypical multidrug resistance: Breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines
    • Phenotype
    • ROSS DD, YANG W, ABRUZZO LV et al: Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines. J. Natl. Cancer Inst (1999) 91:429-433. Phenotype
    • (1999) J. Natl. Cancer Inst , vol.91 , pp. 429-433
    • Ross, D.D.1    Yang, W.2    Abruzzo, L.V.3
  • 109
    • 0031961234 scopus 로고    scopus 로고
    • Reduced cellular accumulation of topotecan: A novel mechanism of resistance in a human ovarian cancer cell line
    • MA J, MALIEPAARD M, NOOTER K et al: Reduced cellular accumulation of topotecan: a novel mechanism of resistance in a human ovarian cancer cell line. Br. J. Cancer (1998) 77:1645-1652.
    • (1998) Br. J. Cancer , vol.77 , pp. 1645-1652
    • Ma, J.1    Maliepaard, M.2    Nooter, K.3
  • 110
    • 0033568540 scopus 로고    scopus 로고
    • Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line
    • MALIEPAARD M, VAN GASTELEN MA, DE JONG LA et al: Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line. Cancer Res. (1999) 59:4559-4563.
    • (1999) Cancer Res. , vol.59 , pp. 4559-4563
    • Maliepaard, M.1    Van Gastelen, M.A.2    De Jong, L.A.3
  • 111
    • 0033199027 scopus 로고    scopus 로고
    • The mouse Bcrp1/Mxr/Abcp gene: Amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin
    • ALLEN JD, BRINKHUIS RF, WIJNHOLDS J, SCHINKEL AH: The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin. Cancer Res. (1999) 59:4237-4241.
    • (1999) Cancer Res. , vol.59 , pp. 4237-4241
    • Allen, J.D.1    Brinkhuis, R.F.2    Wijnholds, J.3    Schinkel, A.H.4
  • 112
    • 0034081847 scopus 로고    scopus 로고
    • The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter MXR (ABCG2)
    • LITMAN T, BRANGI M, HUDSON E et al: The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2).J. Cell Sci. (2000) 113:2011-2021.
    • (2000) J. Cell Sci. , vol.113 , pp. 2011-2021
    • Litman, T.1    Brangi, M.2    Hudson, E.3
  • 113
    • 0033429542 scopus 로고    scopus 로고
    • Camptothecin resistance: Role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR) and potential for glucuronidation in MXR-expressingcells
    • BRANGI M, LITMAN T, CIOTTI M et al: Camptothecin resistance: role of the ATP-binding cassette (ABC), mitoxantrone-resistance half-transporter (MXR) and potential for glucuronidation in MXR-expressingcells. Cancer Res. (1999) 59:5938-5946.
    • (1999) Cancer Res. , vol.59 , pp. 5938-5946
    • Brangi, M.1    Litman, T.2    Ciotti, M.3
  • 114
    • 0029091756 scopus 로고
    • Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase i alterations
    • YANG CJ, HORTON JK, COWAN KH, SCHNEIDER E: Cross-resistance to camptothecin analogues in a mitoxantrone-resistant human breast carcinoma cell line is not due to DNA topoisomerase I alterations. Cancer Res. (1995) 55:4004-4009.
    • (1995) Cancer Res. , vol.55 , pp. 4004-4009
    • Yang, C.J.1    Horton, J.K.2    Cowan, K.H.3    Schneider, E.4
  • 115
    • 0033966957 scopus 로고    scopus 로고
    • Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
    • RABINDRAN SK, ROSS DD, DOYLE LA, YANG W, GREENBERGER LM: Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. (2000) 60:47-50.
    • (2000) Cancer Res. , vol.60 , pp. 47-50
    • Rabindran, S.K.1    Ross, D.D.2    Doyle, L.A.3    Yang, W.4    Greenberger, L.M.5
  • 116
    • 0033990247 scopus 로고    scopus 로고
    • Amplification of 4q21-q22 and the MXR gene in independently derived mitoxantrone-resistant cell lines
    • KNUTSEN T, RAO VK, RIED T et al: Amplification of 4q21-q22 and the MXR gene in independently derived mitoxantrone-resistant cell lines. Genes Chromosomes Cancer (2000) 27:110-116.
    • (2000) Genes Chromosomes Cancer , vol.27 , pp. 110-116
    • Knutsen, T.1    Rao, V.K.2    Ried, T.3
  • 118
    • 0034728768 scopus 로고    scopus 로고
    • The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane
    • ROCCHI E, KHODJAKOV A, VOLK EL et al: The product of the ABC half-transporter gene ABCG2 (BCRP/MXR/ABCP) is expressed in the plasma membrane. Biochem. Biophys. Res. Commun. (2000) 271:42-46.
    • (2000) Biochem. Biophys. Res. Commun. , vol.271 , pp. 42-46
    • Rocchi, E.1    Khodjakov, A.2    Volk, E.L.3
  • 119
    • 18744421466 scopus 로고    scopus 로고
    • Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone-and topotecan-resistant cell lines
    • SCHEFFER GL, MAILEPAARD M., PIJNENBORG ACLM et al: Breast cancer resistance protein is localized at the plasma membrane in mitoxantrone-and topotecan-resistant cell lines. Cancer Res. (2000) 60:2589-2593.
    • (2000) Cancer Res. , vol.60 , pp. 2589-2593
    • Scheffer, G.L.1    Mailepaard, M.2    Pijnenborg, A.C.L.M.3
  • 120
    • 0032695270 scopus 로고    scopus 로고
    • Reversal of resistance by GF120918 in cell lines expressingthe ABC half-transporter MXR
    • DE BRUIN M, MIYAKE K, LITMAN T, ROBEY R, BATES SE: Reversal of resistance by GF120918 in cell lines expressingthe ABC half-transporter, MXR. Cancer Lett. (1999) 146:117-126.
    • (1999) Cancer Lett. , vol.146 , pp. 117-126
    • De Bruin, M.1    Miyake, K.2    Litman, T.3    Robey, R.4    Bates, S.E.5
  • 121
    • 0000786777 scopus 로고    scopus 로고
    • Breast cancer resistance protein (BCRP) associated drug export and p53 inactivation impact flavopiridol (FLA) antitumor activity
    • SCHELGEL S, KLIMECKI W, LIST AF: Breast cancer resistance protein (BCRP) associated drug export and p53 inactivation impact flavopiridol (FLA) antitumor activity. Proc. Amer. Assoc. Cancer Res. (1999) 40.
    • (1999) Proc. Amer. Assoc. Cancer Res. , pp. 40
    • Schelgel, S.1    Klimecki, W.2    List, A.F.3
  • 122
    • 0032322691 scopus 로고    scopus 로고
    • ABC transporters involved in transport of eye pigment precursors in Drosophila melanogaster
    • Ambudkar S, Gottesman MM (Eds.) Academic Press, San Diego, USA
    • EWART GD, HOWELLS AJ: ABC transporters involved in transport of eye pigment precursors in Drosophila melanogaster. In: Methods in Enzymology (Volume 292). Ambudkar S, Gottesman MM (Eds.) Academic Press, San Diego, USA (1998):213-224.
    • (1998) Methods in Enzymology , vol.292 , pp. 213-224
    • Ewart, G.D.1    Howells, A.J.2
  • 123
    • 0029969114 scopus 로고    scopus 로고
    • A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters
    • SHANI N, VALLE D: A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. Proc. Natl. Acad. Sci. USA (1996) 93:11901-11906.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11901-11906
    • Shani, N.1    Valle, D.2
  • 124
    • 0034009217 scopus 로고    scopus 로고
    • Novel mechanisms of drug resistance in leukemia
    • ROSS DD: Novel mechanisms of drug resistance in leukemia. Leukemia (2000) 14:467-473.
    • (2000) Leukemia , vol.14 , pp. 467-473
    • Ross, D.D.1
  • 125
    • 0030069314 scopus 로고    scopus 로고
    • Sequential emergence of MRP-and MDR1-gene over-expression as well as MDR1-gene translocation in homoharringtonine-selected K562 human leukemia cell lines
    • ZHOU DC, RAMOND S, VIGUIE F et al: Sequential emergence of MRP-and MDR1-gene over-expression as well as MDR1-gene translocation in homoharringtonine-selected K562 human leukemia cell lines. Int. J. Cancer (1996) 65:365-371.
    • (1996) Int. J. Cancer , vol.65 , pp. 365-371
    • Zhou, D.C.1    Ramond, S.2    Viguie, F.3
  • 126
    • 0030694313 scopus 로고    scopus 로고
    • Cellular adaptation to drug exposure: Evolution of the drug-resistant phenotype
    • MATSUMOTO Y, TAKANO H, FOJO T: Cellular adaptation to drug exposure: evolution of the drug-resistant phenotype. Cancer Res. (1997) 57:5086-5092.
    • (1997) Cancer Res. , vol.57 , pp. 5086-5092
    • Matsumoto, Y.1    Takano, H.2    Fojo, T.3
  • 127
    • 0030991321 scopus 로고    scopus 로고
    • Detection of in vivo p-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi
    • CHEN CC, MEADOWS B, REGIS J et al: Detection of in vivo p-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi. Clin Cancer Res. (1997) 4:545-552.
    • (1997) Clin Cancer Res. , vol.4 , pp. 545-552
    • Chen, C.C.1    Meadows, B.2    Regis, J.3
  • 128
    • 0032586895 scopus 로고    scopus 로고
    • 99mTc-Sestamibi scanning with SDZ PSC 833 as a functional detection method for resistance modulation in patients with solid tumours
    • BAKKER M, VAN DER GRAAF WT, PIERS DA et al: 99mTc-Sestamibi scanning with SDZ PSC 833 as a functional detection method for resistance modulation in patients with solid tumours. AntiCancer Res. (1999) 19:2349-2353.
    • (1999) AntiCancer Res. , vol.19 , pp. 2349-2353
    • Bakker, M.1    Van Der Graaf, W.T.2    Piers, D.A.3
  • 129
    • 0030921241 scopus 로고    scopus 로고
    • Modulation of the multidrug resistance p-glycoprotein: Detection with technetium-99m-sestamibi in vivo
    • LUKERG D, FACASSO PM, DOBKINJ, PIWNICA-WORMSD: Modulation of the multidrug resistance p-glycoprotein: detection with technetium-99m-sestamibi in vivo. J. Nucl. Med. (1997) 38:369-372.
    • (1997) J. Nucl. Med. , vol.38 , pp. 369-372
    • Lukerg, D.1    Facasso, P.M.2    Dobkin, J.3    Piwnica-Wormsd4
  • 130
    • 0034257083 scopus 로고    scopus 로고
    • Effects of MDR1 and MDR3 P-glycoproteins MRP1 and BCRP/MXR/ABCP on the transport of (99m)Tc-tetrofosmin
    • CHEN WS, LUKER KE, DAHLHEIMER JL et al: Effects of MDR1 and MDR3 P-glycoproteins, MRP1 and BCRP/MXR/ABCP on the transport of (99m)Tc-tetrofosmin. Biochem. Pharmacol (2000) 60:413-426.
    • (2000) Biochem. Pharmacol , vol.60 , pp. 413-426
    • Chen, W.S.1    Luker, K.E.2    Dahlheimer, J.L.3
  • 131
    • 0030041652 scopus 로고    scopus 로고
    • Flow cytometric assay of modulation of P-glycoprotein function in whole blood by the multidrug resistance inhibitor GG918
    • WITHERSPOON SM, EMERSON DL, KERR BM et al: Flow cytometric assay of modulation of P-glycoprotein function in whole blood by the multidrug resistance inhibitor GG918. Clin Cancer Res. (1996) 2:7-12.
    • (1996) Clin Cancer Res. , vol.2 , pp. 7-12
    • Witherspoon, S.M.1    Emerson, D.L.2    Kerr, B.M.3
  • 132
    • 0032960840 scopus 로고    scopus 로고
    • Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833
    • ROBEY R, BAKKE S, STEIN W et al: Efflux of rhodamine from CD56+ cells as a surrogate marker for reversal of P-glycoprotein-mediated drug efflux by PSC 833. Blood (1999) 93:306-314.
    • (1999) Blood , vol.93 , pp. 306-314
    • Robey, R.1    Bakke, S.2    Stein, W.3
  • 133
    • 0028030228 scopus 로고
    • Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute Drug Screen
    • LEE JS, PAULL K, ALVAREZ M et al.: Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute Drug Screen. Mol. Pharmacol. (1994) 46:627-638.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 627-638
    • Lee, J.S.1    Paull, K.2    Alvarez, M.3


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