The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein

British Journal of Pharmacology

Volumn 128, Issue 2, 1999, Pages 403-411

  Martin, Catherine ^a   Berridge, Georgina ^a   Mistry, Prakash ^c   Higgins, Christopher ^b   Charlton, Peter ^c   Callaghan, Richard ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c Cantab Pharmaceuticals Ltd   (United Kingdom)

Author keywords

Drug binding sites; High affinity reversal agent; Multidrug resistance; P glycoprotein

Indexed keywords

ANTHRANILIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC ALKALOID; GLYCOPROTEIN P; PACLITAXEL; TARIQUIDAR; UNCLASSIFIED DRUG; VINBLASTINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; DRUG PROTEIN BINDING; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL MEMBRANE; CHO CELLS; CRICETINAE; DRUG RESISTANCE, NEOPLASM; KINETICS; P-GLYCOPROTEINS; PACLITAXEL; PROTEIN BINDING; QUINOLINES; VINBLASTINE;

EID: 0032881342     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702807     Document Type: Article

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