Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

Cancer Cell

Volumn 1, Issue 1, 2002, Pages 63-74

  Higuchi, Masakazu ^a   O'Brien, Darin ^a   Kumaravelu, Parasakthy ^a   Lenny, Noel ^a   Yeoh, Eng Juh ^a   Downing, James R ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; TRANSCRIPTION FACTOR RUNX1; AML1 ETO FUSION PROTEIN, HUMAN; AML1-ETO FUSION PROTEIN, HUMAN; CELL CYCLE PROTEIN; CRE RECOMBINASE; CYTOKINE; DNA BINDING PROTEIN; INTEGRASE; ONCOPROTEIN; PRIMER DNA; RUNX1 PROTEIN, HUMAN; RUNX1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; VIRUS PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; ALLELE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CHROMOSOME TRANSLOCATION; GENE EXPRESSION; GENE MUTATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LETHALITY; MOUSE; MOUSE STRAIN; MYELOID PROGENITOR CELL; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ACUTE DISEASE; ANIMAL; C57BL MOUSE; CELL DIVISION; CHEMISTRY; CHROMOSOME 21; CHROMOSOME 8; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE TRANSLOCATION; GENETICS; HUMAN; METABOLISM; MOUSE MUTANT; MUTATION; MYELOID LEUKEMIA; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

MURINAE;

ACUTE DISEASE; ANIMALS; CELL CYCLE PROTEINS; CELL DIVISION; CHROMOSOMES, HUMAN, PAIR 21; CHROMOSOMES, HUMAN, PAIR 8; CORE BINDING FACTOR ALPHA 2 SUBUNIT; CYTOKINES; DISEASE MODELS, ANIMAL; DNA PRIMERS; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTEGRASES; LEUKEMIA, MYELOID; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; MUTATION; ONCOGENE PROTEINS, FUSION; PROTO-ONCOGENE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC; VIRAL PROTEINS;

EID: 0036463950     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00016-8     Document Type: Article

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