Exploiting reaction intermediates of the ATPase reaction to elucidate the mechanism of transport by P-glycoprotein (ABCB1)

Journal of Biological Chemistry

Volumn 281, Issue 36, 2006, Pages 26501-26511

  Sauna, Zuben E ^a   Nandigama, Krishnamachary ^a   Ambudkar, Suresh V ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CHANGES; NUCLEOTIDES; P GLYCOPROTEIN; PHOTOAFFINITY;

BERYLLIUM COMPOUNDS; CONFORMATIONS; HYDROLYSIS; LIPIDS; MOLECULAR STRUCTURE; SUBSTRATES;

ADENOSINETRIPHOSPHATE;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; BERYLLIUM FLUORIDE; FLUORIDE; GLYCOPROTEIN P; MUTANT PROTEIN; NUCLEOTIDE; PYROPHOSPHATE; UNCLASSIFIED DRUG; VANADIC ACID;

ARTICLE; BINDING AFFINITY; BINDING SITE; CATALYSIS; CONFORMATIONAL TRANSITION; CROSS LINKING; ENZYME MECHANISM; ENZYME SUBSTRATE; HYDROLYSIS; HYPOTHESIS; KINETICS; LIPID BILAYER; PHOTOAFFINITY LABELING; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; AZIDES; CROSS-LINKING REAGENTS; HUMANS; MICE; MUTATION; NUCLEOTIDES; P-GLYCOPROTEIN; PHOSPHORUS RADIOISOTOPES; VANADATES;

EID: 33748747880     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601917200     Document Type: Article

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