Mitochondrial ATP synthase: Crystal structure of the catalytic F 1 unit in a vanadate-induced transition-like state and implications for mechanism

Journal of Biological Chemistry

Volumn 281, Issue 19, 2006, Pages 13777-13783

  Chen, Chen ^a   Saxena, Ajay K ^b,c   Simcoke, William N ^b,d   Garboczi, David N ^b   Pedersen, Peter L ^a   Ko, Young H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c JAWAHARLAL NEHRU UNIVERSITY   (India)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; CRYSTAL STRUCTURE; DEHYDRATION; PHOSPHATES; PHYSIOLOGICAL MODELS; SUBSTRATES;

ACTIVE SITE REGIONS; MECHANICAL ENERGIES; MITOCHONDRIA; STRUCTURAL MODELS;

ADENOSINETRIPHOSPHATE;

ADENOSINE DIPHOSPHATE; ALANINE; MAGNESIUM CHLORIDE; MITOCHONDRIAL ENZYME; PHOSPHATE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; VANADIC ACID;

ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROPHOBICITY; MALE; NONHUMAN; NUCLEOTIDE BINDING SITE; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; RAT;

ADENOSINE DIPHOSPHATE; ANIMALS; BINDING SITES; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; MAGNESIUM; MALE; MITOCHONDRIA, LIVER; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RATS; RATS, SPRAGUE-DAWLEY; STRUCTURE-ACTIVITY RELATIONSHIP; VANADATES;

EID: 33744949740     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513369200     Document Type: Article

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