메뉴 건너뛰기




Volumn 99, Issue 3, 2006, Pages 323-331

An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in post-menopausal breast cancer survivors

Author keywords

African American; Breast cancer; IRS 1; Polymorphism; Sex hormones

Indexed keywords

C PEPTIDE; ESTRADIOL; ESTRONE; INSULIN RECEPTOR SUBSTRATE 1; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; SOMATOMEDIN C; STEROID HORMONE; TAMOXIFEN; TESTOSTERONE;

EID: 33748375345     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-006-9211-2     Document Type: Article
Times cited : (5)

References (67)
  • 1
    • 0034735873 scopus 로고    scopus 로고
    • Estrogens in the causation of breast, endometrial and ovaria0n cancers - Evidence and hypotheses from epidemiological findings
    • Persson I (2000) Estrogens in the causation of breast, endometrial and ovaria0n cancers - evidence and hypotheses from epidemiological findings. J Steroid Biochem Mol Biol 74(5):357-364
    • (2000) J Steroid Biochem Mol Biol , vol.74 , Issue.5 , pp. 357-364
    • Persson, I.1
  • 2
    • 0029766568 scopus 로고    scopus 로고
    • Influence of plasma estrogen levels on the length of the disease-free interval in postmenopausal women with breast cancer
    • Lonning PE, Helle SI, Johannessen DC, Ekse D, Adlercreutz H (1996) Influence of plasma estrogen levels on the length of the disease-free interval in postmenopausal women with breast cancer. Breast Cancer Res Treat 39(3):335-341
    • (1996) Breast Cancer Res Treat , vol.39 , Issue.3 , pp. 335-341
    • Lonning, P.E.1    Helle, S.I.2    Johannessen, D.C.3    Ekse, D.4    Adlercreutz, H.5
  • 3
    • 0026557343 scopus 로고
    • 133 Randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women
    • Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy, Early Breast Cancer Trialists' Collaborative Group
    • Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy (1992) 133 randomised trials involving 31,000 recurrences and 24,000 deaths among 75,000 women. Early Breast Cancer Trialists' Collaborative Group. Lancet 339(8784):1-15
    • (1992) Lancet , vol.339 , Issue.8784 , pp. 1-15
  • 4
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group
    • Tamoxifen for early breast cancer: an overview of the randomised trials (1998) Early Breast Cancer Trialists' Collaborative Group. Lancet 351(9114):1451-1467
    • (1998) Lancet , vol.351 , Issue.9114 , pp. 1451-1467
  • 5
    • 0142181118 scopus 로고    scopus 로고
    • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: Results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses
    • Baum M, Buzdar A, Cuzick J, Forbes J, Houghton J, Howell A, Sahmoud T (2003) Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update analyses. Cancer 98(9):1802-1810
    • (2003) Cancer , vol.98 , Issue.9 , pp. 1802-1810
    • Baum, M.1    Buzdar, A.2    Cuzick, J.3    Forbes, J.4    Houghton, J.5    Howell, A.6    Sahmoud, T.7
  • 7
    • 0037937417 scopus 로고    scopus 로고
    • Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells
    • Hamelers IH, Steenbergh PH (2003) Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells. Endocr Relat Cancer 10(2):331-345
    • (2003) Endocr Relat Cancer , vol.10 , Issue.2 , pp. 331-345
    • Hamelers, I.H.1    Steenbergh, P.H.2
  • 8
    • 0027942034 scopus 로고
    • The insulin-like growth factor system as a target in breast cancer
    • Yee D (1994) The insulin-like growth factor system as a target in breast cancer. Breast Cancer Res Treat 32(1):85-95
    • (1994) Breast Cancer Res Treat , vol.32 , Issue.1 , pp. 85-95
    • Yee, D.1
  • 9
    • 0031964011 scopus 로고    scopus 로고
    • IGF system components as prognostic markers in breast cancer
    • Lee AV, Hilsenbeck SG, Yee D (1998) IGF system components as prognostic markers in breast cancer. Breast Cancer Res Treat 47(3):295-302
    • (1998) Breast Cancer Res Treat , vol.47 , Issue.3 , pp. 295-302
    • Lee, A.V.1    Hilsenbeck, S.G.2    Yee, D.3
  • 11
    • 0033305004 scopus 로고    scopus 로고
    • Enhancement of insulin-like growth factor signaling in human breast cancer: Estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo
    • Lee AV, Jackson JG, Gooch JL, Hilsenbeck SG, Coronado-Heinsohn E, Osborne CK, Yee D (1999) Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol Endocrinol 13(5):787-796
    • (1999) Mol Endocrinol , vol.13 , Issue.5 , pp. 787-796
    • Lee, A.V.1    Jackson, J.G.2    Gooch, J.L.3    Hilsenbeck, S.G.4    Coronado-Heinsohn, E.5    Osborne, C.K.6    Yee, D.7
  • 13
    • 0032230366 scopus 로고    scopus 로고
    • Extinction of Insulin-like growth factor-i mitogenic signaling by antiestrogen-stimulated Fas-associated protein tyrosine phosphatase-1 in human breast cancer cells
    • Freiss G, Puech C, Vignon F (1998) Extinction of Insulin-like growth factor-i mitogenic signaling by antiestrogen-stimulated Fas-associated protein tyrosine phosphatase-1 in human breast cancer cells. Mol Endocrinol 12(4):568-579
    • (1998) Mol Endocrinol , vol.12 , Issue.4 , pp. 568-579
    • Freiss, G.1    Puech, C.2    Vignon, F.3
  • 14
    • 0025635904 scopus 로고
    • Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells
    • Stewart A, Johnson M, May F, Westley B (1990) Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells. J Biol Chem 265(34):21172-21178
    • (1990) J Biol Chem , vol.265 , Issue.34 , pp. 21172-21178
    • Stewart, A.1    Johnson, M.2    May, F.3    Westley, B.4
  • 15
    • 0030458110 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780
    • Huynh H, Nickerson T, Pollak M, Yang X (1996) Regulation of insulin-like growth factor I receptor expression by the pure antiestrogen ICI 182780. Clin Cancer Res 2(12):2037-2042
    • (1996) Clin Cancer Res , vol.2 , Issue.12 , pp. 2037-2042
    • Huynh, H.1    Nickerson, T.2    Pollak, M.3    Yang, X.4
  • 16
    • 0034724886 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line
    • Molloy CA, May FEB, Westley BR (2000) Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line. J Biol Chem 275(17):12565-12571
    • (2000) J Biol Chem , vol.275 , Issue.17 , pp. 12565-12571
    • Molloy, C.A.1    May, F.E.B.2    Westley, B.R.3
  • 17
    • 0033843445 scopus 로고    scopus 로고
    • Insulin-like growth factor binding proteins (IGFBPs) in breast cancer
    • Perks C, Holly J (2000) Insulin-like growth factor binding proteins (IGFBPs) in breast cancer. J Mammary Gland Biol Neoplasia 5(1):75-84
    • (2000) J Mammary Gland Biol Neoplasia , vol.5 , Issue.1 , pp. 75-84
    • Perks, C.1    Holly, J.2
  • 18
    • 0035971181 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha. A new model for anti-estrogen resistance
    • Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H (2001) Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha. A new model for anti-estrogen resistance. J Biol Chem 276(13):9817-9824
    • (2001) J Biol Chem , vol.276 , Issue.13 , pp. 9817-9824
    • Campbell, R.A.1    Bhat-Nakshatri, P.2    Patel, N.M.3    Constantinidou, D.4    Ali, S.5    Nakshatri, H.6
  • 19
    • 0032814142 scopus 로고    scopus 로고
    • Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha
    • Endoh H, Maruyama K, Masuhiro Y, Kobayashi Y, Goto M, Tai H, Yanagisawa J, Metzger D, Hashimoto S, Kato S (1999) Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha. Mol Cell Biol 19(8):5363-5372
    • (1999) Mol Cell Biol , vol.19 , Issue.8 , pp. 5363-5372
    • Endoh, H.1    Maruyama, K.2    Masuhiro, Y.3    Kobayashi, Y.4    Goto, M.5    Tai, H.6    Yanagisawa, J.7    Metzger, D.8    Hashimoto, S.9    Kato, S.10
  • 21
    • 0030666921 scopus 로고    scopus 로고
    • Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase
    • Dufourny B, Alblas J, van Teeffelen HAAM, van Schaik FMA, van der Burg B, Steenbergh PH, Sussenbach JS (1997) Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase. J Biol Chem 272(49):31163-31171
    • (1997) J Biol Chem , vol.272 , Issue.49 , pp. 31163-31171
    • Dufourny, B.1    Alblas, J.2    Van Teeffelen, H.A.A.M.3    Van Schaik, F.M.A.4    Van Der Burg, B.5    Steenbergh, P.H.6    Sussenbach, J.S.7
  • 22
    • 0036514258 scopus 로고    scopus 로고
    • The Gly972Arg polymorphism in insulin receptor substrate-1 is associated with decreased birth weight in a population-based sample of Brazilian newborns
    • Bezerra RMN, de Castro V, Sales T, Passini R Jr, Marba STM, Saad STO, Saad MJA (2002) The Gly972Arg polymorphism in insulin receptor substrate-1 is associated with decreased birth weight in a population-based sample of Brazilian newborns. Diabetes Care 25(3):550-553
    • (2002) Diabetes Care , vol.25 , Issue.3 , pp. 550-553
    • Bezerra, R.M.N.1    De Castro, V.2    Sales, T.3    Passini Jr., R.4    Marba, S.T.M.5    Saad, S.T.O.6    Saad, M.J.A.7
  • 23
    • 0032540288 scopus 로고    scopus 로고
    • Insulin receptor substrate-1 is the predominant signaling molecule activated by insulin-like growth factor-I, insulin, and interleukin-4 in estrogen receptor-positive human breast cancer cells
    • Jackson JG, White MF, Yee D (1998) Insulin receptor substrate-1 is the predominant signaling molecule activated by insulin-like growth factor-I, insulin, and interleukin-4 in estrogen receptor-positive human breast cancer cells. J Biol Chem 273(16):9994-10003
    • (1998) J Biol Chem , vol.273 , Issue.16 , pp. 9994-10003
    • Jackson, J.G.1    White, M.F.2    Yee, D.3
  • 24
    • 0034810894 scopus 로고    scopus 로고
    • Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
    • Sesti G, Federici M, Hribal ML, Lauro D, Sbraccia P, Lauro R (2001) Defects of the insulin receptor substrate (IRS) system in human metabolic disorders. Faseb J 15(12):2099-2111
    • (2001) Faseb J , vol.15 , Issue.12 , pp. 2099-2111
    • Sesti, G.1    Federici, M.2    Hribal, M.L.3    Lauro, D.4    Sbraccia, P.5    Lauro, R.6
  • 25
    • 0029893417 scopus 로고    scopus 로고
    • A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies
    • Almind K, Inoue G, Pedersen O, Kahn CR (1996) A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies. J Clin Invest 97(11):2569-2575
    • (1996) J Clin Invest , vol.97 , Issue.11 , pp. 2569-2575
    • Almind, K.1    Inoue, G.2    Pedersen, O.3    Kahn, C.R.4
  • 28
    • 0027367546 scopus 로고
    • Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus
    • Almind K, Bjorbaek C, Vestergaard H, Hansen T, Echwald S, Pedersen O (1993) Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus. Lancet 342(8875):828-832
    • (1993) Lancet , vol.342 , Issue.8875 , pp. 828-832
    • Almind, K.1    Bjorbaek, C.2    Vestergaard, H.3    Hansen, T.4    Echwald, S.5    Pedersen, O.6
  • 29
    • 0042572474 scopus 로고    scopus 로고
    • Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: A meta-analysis of 27 studies
    • Jellema A, Zeegers MP, Feskens EJ, Dagnelie PC, Mensink RP (2003) Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies. Diabetologia 46(7):990-995
    • (2003) Diabetologia , vol.46 , Issue.7 , pp. 990-995
    • Jellema, A.1    Zeegers, M.P.2    Feskens, E.J.3    Dagnelie, P.C.4    Mensink, R.P.5
  • 31
    • 0345505293 scopus 로고    scopus 로고
    • Intima media thickness of carotid arteries is reduced in heterozygous carriers of the Gly972Arg variant in the insulin receptor substrate-1 gene
    • Holzl B, Iglseder B, Stadlmayr A, Hedegger M, More E, Reiter R, Sandhofer F, Paulweber B (2003) Intima media thickness of carotid arteries is reduced in heterozygous carriers of the Gly972Arg variant in the insulin receptor substrate-1 gene. Eur J Clin Invest 33(2):110-116
    • (2003) Eur J Clin Invest , vol.33 , Issue.2 , pp. 110-116
    • Holzl, B.1    Iglseder, B.2    Stadlmayr, A.3    Hedegger, M.4    More, E.5    Reiter, R.6    Sandhofer, F.7    Paulweber, B.8
  • 32
    • 0032587076 scopus 로고    scopus 로고
    • The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells
    • Porzio O, Federici M, Hribal ML, Lauro D, Accili D, Lauro R, Borboni P, Sesti G (1999) The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells. J Clin Invest 104(3):357-364
    • (1999) J Clin Invest , vol.104 , Issue.3 , pp. 357-364
    • Porzio, O.1    Federici, M.2    Hribal, M.L.3    Lauro, D.4    Accili, D.5    Lauro, R.6    Borboni, P.7    Sesti, G.8
  • 34
    • 0036143753 scopus 로고    scopus 로고
    • IRS-1 Gly971Arg variant is not a new risk factor for coronary artery disease in the Taiwanese population
    • Tsai C-T, Hwang J-J, Lai L-P, Chiang F-T, Tseng Y-Z (2002) IRS-1 Gly971Arg variant is not a new risk factor for coronary artery disease in the Taiwanese population. Arterioscler Thromb Vasc Biol 22(1):194
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , Issue.1 , pp. 194
    • Tsai, C.-T.1    Hwang, J.-J.2    Lai, L.-P.3    Chiang, F.-T.4    Tseng, Y.-Z.5
  • 35
    • 0020417830 scopus 로고
    • Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature
    • Sodergard R, Backstrom T, Shanbhag V, Carstensen H (1982) Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature. J Steroid Biochem 16(6):801-810
    • (1982) J Steroid Biochem , vol.16 , Issue.6 , pp. 801-810
    • Sodergard, R.1    Backstrom, T.2    Shanbhag, V.3    Carstensen, H.4
  • 38
    • 0033006003 scopus 로고    scopus 로고
    • Allelic discrimination using fluorogenic probes and the 5′; nuclease assay
    • Livak KJ (1999) Allelic discrimination using fluorogenic probes and the 5′; nuclease assay. Genet Anal 14(5-6):143-149
    • (1999) Genet Anal , vol.14 , Issue.5-6 , pp. 143-149
    • Livak, K.J.1
  • 39
    • 0037048695 scopus 로고    scopus 로고
    • Prevalence and trends in overweight among US children and adolescents, 1999-2000
    • Ogden CL, Flegal KM, Carroll MD, Johnson CL (2002) Prevalence and trends in overweight among US children and adolescents, 1999-2000. JAMA 288(14):1728-1732
    • (2002) JAMA , vol.288 , Issue.14 , pp. 1728-1732
    • Ogden, C.L.1    Flegal, K.M.2    Carroll, M.D.3    Johnson, C.L.4
  • 40
    • 0035461406 scopus 로고    scopus 로고
    • Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome
    • El Mkadem SA, Lautier C, Macari F, Molinari N, Lefebvre P, Renard E, Gris JC, Cros G, Daures JP, Bringer J, et al (2001) Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome. Diabetes 50(9):2164-2168
    • (2001) Diabetes , vol.50 , Issue.9 , pp. 2164-2168
    • El Mkadem, S.A.1    Lautier, C.2    Macari, F.3    Molinari, N.4    Lefebvre, P.5    Renard, E.6    Gris, J.C.7    Cros, G.8    Daures, J.P.9    Bringer, J.10
  • 42
    • 0037370703 scopus 로고    scopus 로고
    • Socioeconomic status and breast carcinoma survival in four racial/ethnic groups: A population-based study
    • O'Malley CD, Le GM, Glaser SL, Shema SJ, West DW (2003) Socioeconomic status and breast carcinoma survival in four racial/ethnic groups: a population-based study. Cancer 97(5):1303-1311
    • (2003) Cancer , vol.97 , Issue.5 , pp. 1303-1311
    • O'Malley, C.D.1    Le, G.M.2    Glaser, S.L.3    Shema, S.J.4    West, D.W.5
  • 43
    • 0030059963 scopus 로고    scopus 로고
    • Racial differences in survival of female breast cancer in the Detroit metropolitan area
    • Simon MS, Severson RK (1996) Racial differences in survival of female breast cancer in the Detroit metropolitan area. Cancer 77(2):308-314
    • (1996) Cancer , vol.77 , Issue.2 , pp. 308-314
    • Simon, M.S.1    Severson, R.K.2
  • 44
    • 0021924754 scopus 로고
    • Race-related differences in breast cancer patients. Results of the 1982 national survey of breast cancer by the American College of Surgeons
    • Natarajan N, Nemoto T, Mettlin C, Murphy GP (1985) Race-related differences in breast cancer patients. Results of the 1982 national survey of breast cancer by the American College of Surgeons. Cancer 56(7):1704-1709
    • (1985) Cancer , vol.56 , Issue.7 , pp. 1704-1709
    • Natarajan, N.1    Nemoto, T.2    Mettlin, C.3    Murphy, G.P.4
  • 45
    • 0042061003 scopus 로고    scopus 로고
    • Influences of ethnicity, treatment, and comorbidity on breast cancer survival in Hawaii
    • Maskarinec G, Pagano IS, Yamashiro G, Issell BF (2003) Influences of ethnicity, treatment, and comorbidity on breast cancer survival in Hawaii. J Clin Epidemiol 56(7):678-685
    • (2003) J Clin Epidemiol , vol.56 , Issue.7 , pp. 678-685
    • Maskarinec, G.1    Pagano, I.S.2    Yamashiro, G.3    Issell, B.F.4
  • 46
    • 0037346703 scopus 로고    scopus 로고
    • Racial differences in genetic factors associated with breast cancer
    • Ademuyiwa FO, Olopade OI (2003) Racial differences in genetic factors associated with breast cancer. Cancer Metastasis Rev 22(1):47-53
    • (2003) Cancer Metastasis Rev , vol.22 , Issue.1 , pp. 47-53
    • Ademuyiwa, F.O.1    Olopade, O.I.2
  • 48
  • 49
    • 0029857775 scopus 로고    scopus 로고
    • UKPDS 19: Heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations
    • Zhang Y, Wat N, Stratton IM, Warren-Perry MG, Orho M, Groop L, Turner RC (1996) UKPDS 19: heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations. Diabetologia 39(12):1505-1511
    • (1996) Diabetologia , vol.39 , Issue.12 , pp. 1505-1511
    • Zhang, Y.1    Wat, N.2    Stratton, I.M.3    Warren-Perry, M.G.4    Orho, M.5    Groop, L.6    Turner, R.C.7
  • 51
    • 0034671645 scopus 로고    scopus 로고
    • Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo
    • Previs SF, Withers DJ, Ren J-M, White MF, Shulman GI (2000) Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo. J Biol Chem 275(50):38990-38994
    • (2000) J Biol Chem , vol.275 , Issue.50 , pp. 38990-38994
    • Previs, S.F.1    Withers, D.J.2    Ren, J.-M.3    White, M.F.4    Shulman, G.I.5
  • 53
    • 0032587076 scopus 로고    scopus 로고
    • The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic {beta} cells
    • Porzio O, Federici M, Hribal ML, Lauro D, Accili D, Lauro R, Borboni P, Sesti G (1999) The Gly972→Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic {beta} cells. J Clin Invest 104(3):357-364
    • (1999) J Clin Invest , vol.104 , Issue.3 , pp. 357-364
    • Porzio, O.1    Federici, M.2    Hribal, M.L.3    Lauro, D.4    Accili, D.5    Lauro, R.6    Borboni, P.7    Sesti, G.8
  • 54
    • 0036270579 scopus 로고    scopus 로고
    • Upper abdominal obesity, insulin resistance and breast cancer risk
    • Stoll BA (2002) Upper abdominal obesity, insulin resistance and breast cancer risk. Int J Obes Relat Metab Disord 26(6):747-753
    • (2002) Int J Obes Relat Metab Disord , vol.26 , Issue.6 , pp. 747-753
    • Stoll, B.A.1
  • 55
    • 0030734929 scopus 로고    scopus 로고
    • Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus
    • Imai Y, Philippe N, Sesti G, Accili D, Taylor SI (1997) Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 82(12):4201-4207
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.12 , pp. 4201-4207
    • Imai, Y.1    Philippe, N.2    Sesti, G.3    Accili, D.4    Taylor, S.I.5
  • 57
    • 0027422281 scopus 로고
    • Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families
    • Hager J, Zouali H, Velho G, Froguel P (1993) Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families. Lancet 342(8884):1430
    • (1993) Lancet , vol.342 , Issue.8884 , pp. 1430
    • Hager, J.1    Zouali, H.2    Velho, G.3    Froguel, P.4
  • 58
    • 0027994029 scopus 로고
    • Insulin receptor substrate-1 variants in non-insulin-dependent diabetes
    • Laakso M, Malkki M, Kekalainen P, Kuusisto J, Deeb SS (1994) Insulin receptor substrate-1 variants in non-insulin-dependent diabetes. J Clin Invest 94(3):1141-1146
    • (1994) J Clin Invest , vol.94 , Issue.3 , pp. 1141-1146
    • Laakso, M.1    Malkki, M.2    Kekalainen, P.3    Kuusisto, J.4    Deeb, S.S.5
  • 59
    • 0029666050 scopus 로고    scopus 로고
    • No association between the Gly971Arg variant of the insulin receptor substrate 1 gene and NIDDM in the Taiwanese population
    • Chuang LM, Lai CS, Yeh JI, Wu HP, Tai TY, Lin BJ (1996) No association between the Gly971Arg variant of the insulin receptor substrate 1 gene and NIDDM in the Taiwanese population. Diabetes Care 19(5):446-449
    • (1996) Diabetes Care , vol.19 , Issue.5 , pp. 446-449
    • Chuang, L.M.1    Lai, C.S.2    Yeh, J.I.3    Wu, H.P.4    Tai, T.Y.5    Lin, B.J.6
  • 61
    • 0029968888 scopus 로고    scopus 로고
    • Relationship between insulin sensitivity and insulin receptor substrate-1 mutations in non-diabetic relatives of NIDDM families
    • Armstrong M, Haldane F, Avery PJ, Mitcheson J, Stewart MW, Turnbull DM, Walker M (1996) Relationship between insulin sensitivity and insulin receptor substrate-1 mutations in non-diabetic relatives of NIDDM families. Diabet Med 13(4):341-345
    • (1996) Diabet Med , vol.13 , Issue.4 , pp. 341-345
    • Armstrong, M.1    Haldane, F.2    Avery, P.J.3    Mitcheson, J.4    Stewart, M.W.5    Turnbull, D.M.6    Walker, M.7
  • 62
    • 9244256729 scopus 로고    scopus 로고
    • Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: Identification of five novel polymorphisms
    • Ura S, Araki E, Kishikawa H, Shirotani T, Todaka M, Isami S, Shimoda S, Yoshimura R, Matsuda K, Motoyoshi S, et al (1996) Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms. Diabetologia 39(5):600-608
    • (1996) Diabetologia , vol.39 , Issue.5 , pp. 600-608
    • Ura, S.1    Araki, E.2    Kishikawa, H.3    Shirotani, T.4    Todaka, M.5    Isami, S.6    Shimoda, S.7    Yoshimura, R.8    Matsuda, K.9    Motoyoshi, S.10
  • 63
    • 0032878846 scopus 로고    scopus 로고
    • Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes
    • Koch M, Rett K, Volk A, Maerker E, Haist K, Deninger M, Renn W, Haring HU (1999) Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes. Exp Clin Endocrinol Diabetes 107(5):318-322
    • (1999) Exp Clin Endocrinol Diabetes , vol.107 , Issue.5 , pp. 318-322
    • Koch, M.1    Rett, K.2    Volk, A.3    Maerker, E.4    Haist, K.5    Deninger, M.6    Renn, W.7    Haring, H.U.8
  • 64
    • 0036828097 scopus 로고    scopus 로고
    • Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: Therapeutic implications
    • Chang Q, Li Y, White MF, Fletcher JA, Xiao S (2002) Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: therapeutic implications. Cancer Res 62(21):6035-6038
    • (2002) Cancer Res , vol.62 , Issue.21 , pp. 6035-6038
    • Chang, Q.1    Li, Y.2    White, M.F.3    Fletcher, J.A.4    Xiao, S.5
  • 65
    • 0037508559 scopus 로고    scopus 로고
    • Developmental and hormonal signals dramatically alter the localization and abundance of insulin receptor substrate proteins in the mammary gland
    • Lee AV, Zhang P, Ivanova M, Bonnette S, Oesterreich S, Rosen JM, Grimm S, Hovey RC, Vonderhaar BK, Kahn CR, et al (2003) Developmental and hormonal signals dramatically alter the localization and abundance of insulin receptor substrate proteins in the mammary gland. Endocrinology 144(6):2683-2694
    • (2003) Endocrinology , vol.144 , Issue.6 , pp. 2683-2694
    • Lee, A.V.1    Zhang, P.2    Ivanova, M.3    Bonnette, S.4    Oesterreich, S.5    Rosen, J.M.6    Grimm, S.7    Hovey, R.C.8    Vonderhaar, B.K.9    Kahn, C.R.10
  • 67
    • 0034967344 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: New insights into their synergistic effects
    • Dupont J, Le Roith D (2001) Insulin-like growth factor 1 and oestradiol promote cell proliferation of MCF-7 breast cancer cells: new insights into their synergistic effects. Mol Pathol 54(3):149-15
    • (2001) Mol Pathol , vol.54 , Issue.3 , pp. 149-215
    • Dupont, J.1    Le Roith, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.