Estrogens in the causation of breast, endometrial and ovarian cancers - Evidence and hypotheses from epidemiological findings

Journal of Steroid Biochemistry and Molecular Biology

Volumn 74, Issue 5, 2000, Pages 357-364

  Persson, Ingemar ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Breast cancer; Endometrial cancer; Estrogen; Ovarian cancer

Indexed keywords

CLOMIFENE; ESTROGEN; GESTAGEN; ORAL CONTRACEPTIVE AGENT; PROGESTERONE; TAMOXIFEN;

BREAST CARCINOGENESIS; BREAST CARCINOMA; CANCER PREVENTION; CANCER RISK; CANCER SUSCEPTIBILITY; CONFERENCE PAPER; ENDOMETRIUM CARCINOMA; ESTROGEN THERAPY; HORMONAL CARCINOGENESIS; HUMAN; NONHUMAN; ORAL CONTRACEPTION; OVARY CARCINOMA; PREGNANCY; RISK FACTOR;

AGE FACTORS; ALCOHOL DRINKING; ANTHROPOMETRY; BREAST NEOPLASMS; CONTRACEPTIVES, ORAL, COMBINED; DIET; ENDOMETRIAL NEOPLASMS; ESTROGENS; EXERCISE; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HORMONE REPLACEMENT THERAPY; HUMANS; MALE; MENARCHE; MENOPAUSE; OVARIAN NEOPLASMS; REPRODUCTION; RISK FACTORS; SEX FACTORS; SMOKING;

ANIMALIA;

EID: 0034735873     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00113-8     Document Type: Conference Paper

References (67)

1. Cancer incidence in five continents
2. Cancer: Causes, occurrence and control
3. Trends in cancer incidence and mortality
4. Epidemiology of breast cancer
5. Comparative epidemiology of cancers of the colon; rectum; prostate and breast in Shanghai; China versus the United States
6. A review of the epidemiology of human breast cancer
7. Steroid hormones and risk of breast cancer
8. Hypothesis: Does breast cancer originate in utero?
9. The aetiology and pathogenesis of human breast cancer
10. Towards an understanding of breast cancer etiology
11. Evidence of prenatal influences on breast cancer risk
12. Perinatal factors and risk of breast cancer
13. Birthweight as a risk factor for breast cancer
14. Perinatal characteristics and adult mammographic patterns
15. 'Hormonal' risk factors; 'breast tissue age' and the age-incidence of breast cancer
16. Transient increase in the risk of breast cancer after giving birth
17. Body size in different periods of life and breast cancer risk in post-menopausal women
18. Alcohol; height; and adiposity in relation to estrogen and prolactin levels in postmenopausal women
19. Determinants of age at menarche as early life predictors of breast cancer risk
20. Does physical activity reduce risk of estrogen-dependent cancer in women?
21. Diet; body size; and breast cancer
22. Relationship between estrogen levels; use of hormone replacement therapy; and breast cancer
23. Breast cancer and hormonal contraceptives: Collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies
24. Breast cancer and hormone replacement therapy: Collaborative reanalysis of data from 51 epidemiological studies of 52 705 women with breast cancer and 108 411 women without breast cancer
25. The role of reproductive factors and use of oral contraceptives in the aetiology of breast cancer in women aged 50 to 74 years
26. Progesterone and estrogen receptors and mammary neoplasia in the Iowa Women's Health Study: How many kinds of breast cancer are there?
27. Mammographic features and breast cancer risk: Effects with time; age; and menopause status
28. Breast augmentation: A risk factor for breast cancer?
29. Breast cancer incidence subsequent to surgical reduction of the female breast
30. Growth and development of the human infant breast
31. A maternal diet high in n-6 polyunsaturated fats alters mammary gland development; puberty onset; and breast cancer risk among female rat offspring
32. Influence of age and parity on the development of the human breast
33. Estrogenic regulation of growth and polypeptide growth factor secretion in human breast carcinoma
34. Molecular mechanisms of estrogen carcinogenesis
35. Epidemiology of cancer: Global patterns and trends
36. Endometrial carcinoma: Two diseases?
37. Hormone replacement therapy and endometrial cancer risk: A meta-analysis
38. Trends in endometrial cancer incidence and mortality in Sweden; 1960-1984
39. Chemotherapy of breast cancer. A general overview
40. Nutrition; hormones; and breast cancer: Is insulin the missing link?
41. Past and present physical activity and endometrial cancer risk
42. Endometrial cancer
43. Tamoxifen for early breast cancer: An overview of the randomised trials
44. Granulosa-cell and theca-cell tumors. The clinical picture and long-term outcome for the Radiumhemmet series
45. Risk factors and hormone levels in patients with serous and endometrioid uterine carcinomas
46. Some hormones; Postmenopausal hormone therapy and hormonal contraception
47. Use of oral contraceptives and endometrial cancer risk
48. Risk of endometrial cancer in relation to use of oestrogen combined with cyclic progestagen therapy in postmenopausal women
49. Estrogen-progestin replacement therapy and endometrial cancer
50. Estimates of the worldwide mortality from eighteen major cancers in 1985. Implications for prevention and projections of future burden
51. Incessant ovulation - A factor in ovarian neoplasia?
52. Letter: The etiology and prevention of ovarian cancer
53. Epidemiologic evidence for uterine growth factors in the pathogenesis of ovarian cancer
54. Parity; age at first childbirth; and risk of ovarian cancer
55. Hormonal etiology of epithelial ovarian cancer; with a hypothesis concerning the role of androgens and progesterone
56. Hormonal aspects of epithelial ovarian cancer: Review of epidemiological evidence
57. Infertility; fertility drugs; and invasive ovarian cancer: A case-control study
58. A quantitative assessment of oral contraceptive use and risk of ovarian cancer
59. Hormone replacement therapy and the risk of epithelial ovarian carcinoma: A meta-analysis
60. Estrogen replacement therapy and risk of epithelial ovarian cancer
61. Estrogen replacement therapy and fatal ovarian cancer
62. Characteristics relating to ovarian cancer risk: Collaborative analysis of 12 US case-control studies. IV. The pathogenesis of epithelial ovarian cancer
63. Ovarian tumors in a cohort of infertile women
64. Breast and ovarian cancer incidence after infertility and in vitro fertilisation
65. Parity; contraception; infertility; and the risk of epithelial ovarian cancer
66. Effect of progestin on the ovarian epithelium of macaques: Cancer prevention through apoptosis?