-
1
-
-
27144488229
-
Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma
-
Achanta G., Sasaki R., Feng L., Carew J.S., Lu W., Pelicano H., Keating M.J., and Huang P. 2005. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J. 24: 3482.
-
(2005)
EMBO J.
, vol.24
, pp. 3482
-
-
Achanta, G.1
Sasaki, R.2
Feng, L.3
Carew, J.S.4
Lu, W.5
Pelicano, H.6
Keating, M.J.7
Huang, P.8
-
2
-
-
0030925951
-
Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis
-
Alonso A., Martin P., Albarran C., Aquilera B., Garcia O., Guzman A., Oliva H., and Sancho M. 1997. Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis. Electrophoresis 18: 682.
-
(1997)
Electrophoresis
, vol.18
, pp. 682
-
-
Alonso, A.1
Martin, P.2
Albarran, C.3
Aquilera, B.4
Garcia, O.5
Guzman, A.6
Oliva, H.7
Sancho, M.8
-
3
-
-
0032443803
-
The akt kinase: Molecular determinants of oncogenicity
-
Aoki M., Batista O., Bellacosa A., Tsichlis P., and Vogt P.K. 1998. The akt kinase: Molecular determinants of oncogenicity. Proc. Natl. Acad. Sci. 95: 14950.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 14950
-
-
Aoki, M.1
Batista, O.2
Bellacosa, A.3
Tsichlis, P.4
Vogt, P.K.5
-
4
-
-
0034964421
-
Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma
-
Astuti D., Latif F., Dallol A., Dahia P.L., Douglas F., George E., Skoldberg F., Husebye E.S., Eng C., and Maher E.R. 2001. Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Am. J. Hum. Genet. 69: 49.
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 49
-
-
Astuti, D.1
Latif, F.2
Dallol, A.3
Dahia, P.L.4
Douglas, F.5
George, E.6
Skoldberg, F.7
Husebye, E.S.8
Eng, C.9
Maher, E.R.10
-
5
-
-
0034602950
-
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
-
Baysal B.E., Ferrell R.E., Willett-Brozick J.E., Lawrence E.C., Myssiorek D., Bosch A., van der Mey A., Taschner P.E., Rubinstein W.S., Myers E.N., Richard C.W., Cornelisse C.J., Devilee P., and Devlin B. 2000. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science 287: 848.
-
(2000)
Science
, vol.287
, pp. 848
-
-
Baysal, B.E.1
Ferrell, R.E.2
Willett-Brozick, J.E.3
Lawrence, E.C.4
Myssiorek, D.5
Bosch, A.6
Van Der Mey, A.7
Taschner, P.E.8
Rubinstein, W.S.9
Myers, E.N.10
Richard, C.W.11
Cornelisse, C.J.12
Devilee, P.13
Devlin, B.14
-
6
-
-
0026095665
-
A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region
-
Bellacosa A., Testa J.R., Staal S.P., and Tsichlis P.N. 1991. A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region. Science 254: 274.
-
(1991)
Science
, vol.254
, pp. 274
-
-
Bellacosa, A.1
Testa, J.R.2
Staal, S.P.3
Tsichlis, P.N.4
-
7
-
-
0029019959
-
Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients
-
Bianchi M.S., Bianchi N.O., and Bailliet G. 1995. Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients. Cytogenet. Cell Genet. 71: 99.
-
(1995)
Cytogenet. Cell Genet.
, vol.71
, pp. 99
-
-
Bianchi, M.S.1
Bianchi, N.O.2
Bailliet, G.3
-
8
-
-
10644290828
-
On the InterAktion between hexokinase and the mitochondrion
-
Birnbaum M.J. 2004. On the InterAktion between hexokinase and the mitochondrion. Dev. Cell 7: 781.
-
(2004)
Dev. Cell
, vol.7
, pp. 781
-
-
Birnbaum, M.J.1
-
9
-
-
0029159804
-
Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency
-
Bourgeron T., Rustin P., Chretien D., Birch-Machin M., Bourgeois M., Viegas-Pequignot E., Munnich A., and Rotig A. 1995. Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency. Nat. Genet. 11: 144.
-
(1995)
Nat. Genet.
, vol.11
, pp. 144
-
-
Bourgeron, T.1
Rustin, P.2
Chretien, D.3
Birch-Machin, M.4
Bourgeois, M.5
Viegas-Pequignot, E.6
Munnich, A.7
Rotig, A.8
-
11
-
-
2342565881
-
Advances in protein kinase B signalling: AKTion on multiple fronts
-
Brazil D.P., Yang Z.Z., and Hemmings B.A. 2004. Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem. Sci. 29: 233.
-
(2004)
Trends Biochem. Sci.
, vol.29
, pp. 233
-
-
Brazil, D.P.1
Yang, Z.Z.2
Hemmings, B.A.3
-
12
-
-
0027230737
-
A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies
-
Brockington M., Sweeney M.G., Hammans S.R., Morgan-Hughes J.A., and Harding A.E. 1993. A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies. Nat. Genet. 4: 67.
-
(1993)
Nat. Genet.
, vol.4
, pp. 67
-
-
Brockington, M.1
Sweeney, M.G.2
Hammans, S.R.3
Morgan-Hughes, J.A.4
Harding, A.E.5
-
13
-
-
0042575733
-
High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase
-
Bustamante E. and Pedersen P.L. 1977. High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase. Proc. Natl. Acad. Sci. 74: 3735.
-
(1977)
Proc. Natl. Acad. Sci.
, vol.74
, pp. 3735
-
-
Bustamante, E.1
Pedersen, P.L.2
-
14
-
-
0033805327
-
Separation of cytochrome c-dependent caspase activation from thiol-disulfide redox change in cells lacking mitochondrial DNA
-
Cai J., Wallace D.C., Zhivotovsky B., and Jones D.P. 2000. Separation of cytochrome c-dependent caspase activation from thiol-disulfide redox change in cells lacking mitochondrial DNA. Free Radic. Biol. Med. 29: 334.
-
(2000)
Free Radic. Biol. Med.
, vol.29
, pp. 334
-
-
Cai, J.1
Wallace, D.C.2
Zhivotovsky, B.3
Jones, D.P.4
-
15
-
-
0023163377
-
Mitochondrial DNA and human evolution
-
Cann R.L., Stoneking M., and Wilson A.C. 1987. Mitochondrial DNA and human evolution. Nature 325: 31.
-
(1987)
Nature
, vol.325
, pp. 31
-
-
Cann, R.L.1
Stoneking, M.2
Wilson, A.C.3
-
16
-
-
24744442376
-
Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women
-
Canter J.A., Kallianpur A.R., Parl F.F., and Millikan R.C. 2005. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res. 65: 8028.
-
(2005)
Cancer Res.
, vol.65
, pp. 8028
-
-
Canter, J.A.1
Kallianpur, A.R.2
Parl, F.F.3
Millikan, R.C.4
-
17
-
-
0141703199
-
Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis
-
Chen J.Z., Gokden N., Greene G.F., Green B., and Kadlubar F.F. 2003. Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis. Carcinogenesis 24: 1481.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1481
-
-
Chen, J.Z.1
Gokden, N.2
Greene, G.F.3
Green, B.4
Kadlubar, F.F.5
-
18
-
-
0037112431
-
Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection
-
Chen J.Z., Gokden N., Greene G.F., Mukunyadzi P., and Kadlubar F.F. 2002. Extensive somatic mitochondrial mutations in primary prostate cancer using laser capture microdissection. Cancer Res. 62: 6470.
-
(2002)
Cancer Res.
, vol.62
, pp. 6470
-
-
Chen, J.Z.1
Gokden, N.2
Greene, G.F.3
Mukunyadzi, P.4
Kadlubar, F.F.5
-
19
-
-
0037180245
-
Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: Is there a common mechanism?
-
Chinnery P.F., Samuels D.C., Elson J., and Turnbull D.M. 2002. Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: Is there a common mechanism? Lancet 360: 1323.
-
(2002)
Lancet
, vol.360
, pp. 1323
-
-
Chinnery, P.F.1
Samuels, D.C.2
Elson, J.3
Turnbull, D.M.4
-
20
-
-
0014965217
-
Homology and structural relationships between the dimeric and monomeric circular forms of mitochondrial DNA from human leukemic leukocytes
-
Clayton D.A., Davis R.W., and Vinograd J. 1970. Homology and structural relationships between the dimeric and monomeric circular forms of mitochondrial DNA from human leukemic leukocytes. J. Mol. Biol. 47: 137.
-
(1970)
J. Mol. Biol.
, vol.47
, pp. 137
-
-
Clayton, D.A.1
Davis, R.W.2
Vinograd, J.3
-
23
-
-
0039250954
-
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
-
Fliss M.S., Usadel H., Caballero O.L., Wu L., Buta M.R., Eleff S.M., Jen J., and Sidransky D. 2000. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287: 2017.
-
(2000)
Science
, vol.287
, pp. 2017
-
-
Fliss, M.S.1
Usadel, H.2
Caballero, O.L.3
Wu, L.4
Buta, M.R.5
Eleff, S.M.6
Jen, J.7
Sidransky, D.8
-
24
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby R.A. and Gillies R.J. 2004. Why do cancers have high aerobic glycolysis? Nat. Rev. Cancer 4: 891.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 891
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
25
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio M., Migliaccio E., Orsini F., Paolucci D., Moroni M., Contursi C., Pelliccia G., Luzi L., Minucci S., Marcaccio M., Pinton P., Rizzuto R., Bernardi P., Paolucci F., and Pelicci P.G. 2005. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell 122: 221.
-
(2005)
Cell
, vol.122
, pp. 221
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
26
-
-
0022729121
-
Increased levels of mitochondrial gene expression in rat fibroblast cells immortalized or transformed by viral and cellular oncogenes
-
Glaichenhaus N., Leopold P., and Cuzin F. 1986. Increased levels of mitochondrial gene expression in rat fibroblast cells immortalized or transformed by viral and cellular oncogenes. EMBO J. 5: 1261.
-
(1986)
EMBO J.
, vol.5
, pp. 1261
-
-
Glaichenhaus, N.1
Leopold, P.2
Cuzin, F.3
-
27
-
-
0038012340
-
Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression
-
Goel A., Mathupala S.P., and Pedersen P.L. 2003. Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression. J. Biol. Chem. 278: 15333.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15333
-
-
Goel, A.1
Mathupala, S.P.2
Pedersen, P.L.3
-
28
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
Gottlob K., Majewski N., Kennedy S., Kandel E., Robey R.B., and Hay N. 2001. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 15: 1406.
-
(2001)
Genes Dev.
, vol.15
, pp. 1406
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
Kandel, E.4
Robey, R.B.5
Hay, N.6
-
29
-
-
0032729633
-
Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability
-
Habano W., Sugai T., Yoshida T., and Nakamura S. 1999. Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability. Int. J. Cancer 83: 625.
-
(1999)
Int. J. Cancer
, vol.83
, pp. 625
-
-
Habano, W.1
Sugai, T.2
Yoshida, T.3
Nakamura, S.4
-
30
-
-
0023099924
-
Genetic differences in effects of food restriction on aging in mice
-
Harrison D.E. and Archer J.R. 1987. Genetic differences in effects of food restriction on aging in mice. J. Nutr. 117: 376.
-
(1987)
J. Nutr.
, vol.117
, pp. 376
-
-
Harrison, D.E.1
Archer, J.R.2
-
31
-
-
12444342982
-
Mitochondrial proteome: Altered cytochrome c oxidase subunit levels in prostate cancer
-
Herrmann P.C., Gillespie J.W., Charboneau L., Bichsel V.E., Paweletz C.P., Calvert V.S., Kohn E.C., Emmert-Buck M.R., Liotta L.A., and Petricoin E.F., III. 2003. Mitochondrial proteome: altered cytochrome c oxidase subunit levels in prostate cancer. Proteomics 3: 1801.
-
(2003)
Proteomics
, vol.3
, pp. 1801
-
-
Herrmann, P.C.1
Gillespie, J.W.2
Charboneau, L.3
Bichsel, V.E.4
Paweletz, C.P.5
Calvert, V.S.6
Kohn, E.C.7
Emmert-Buck, M.R.8
Liotta, L.A.9
Petricoin III, E.F.10
-
32
-
-
0023883150
-
Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies
-
Holt I.J., Harding A.E., and Morgan-Hughes J.A. 1988. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 331: 717.
-
(1988)
Nature
, vol.331
, pp. 717
-
-
Holt, I.J.1
Harding, A.E.2
Morgan-Hughes, J.A.3
-
34
-
-
0030030467
-
Novel mitochondrial DNA deletion found in a renal cell carcinoma
-
Horton T.M., Petros J.A., Heddi A., Shoffner J., Kaufman A.E., Graham S.D., Jr., Gramlich T., and Wallace D.C. 1996. Novel mitochondrial DNA deletion found in a renal cell carcinoma. Genes Chromosomes Cancer 15: 95.
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 95
-
-
Horton, T.M.1
Petros, J.A.2
Heddi, A.3
Shoffner, J.4
Kaufman, A.E.5
Graham Jr., S.D.6
Gramlich, T.7
Wallace, D.C.8
-
35
-
-
0032514466
-
A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes
-
Ishii N., Fujii M., Hartman P.S., Tsuda M., Yasuda K., Senoo-Matsuda N., Yanase S., Ayusawa D., and Suzuki K. 1998. A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes. Nature 394: 694.
-
(1998)
Nature
, vol.394
, pp. 694
-
-
Ishii, N.1
Fujii, M.2
Hartman, P.S.3
Tsuda, M.4
Yasuda, K.5
Senoo-Matsuda, N.6
Yanase, S.7
Ayusawa, D.8
Suzuki, K.9
-
36
-
-
17944367327
-
Mitochondrial mutations in early stage prostate cancer and bodily fluids
-
Jeronimo C., Nomoto S., Caballero O.L., Usadel H., Henrique R., Varzim G., Oliveira J., Lopes C., Fliss M.S., and Sidransky D. 2001. Mitochondrial mutations in early stage prostate cancer and bodily fluids. Oncogene 20: 5195.
-
(2001)
Oncogene
, vol.20
, pp. 5195
-
-
Jeronimo, C.1
Nomoto, S.2
Caballero, O.L.3
Usadel, H.4
Henrique, R.5
Varzim, G.6
Oliveira, J.7
Lopes, C.8
Fliss, M.S.9
Sidransky, D.10
-
37
-
-
0020959568
-
Radiation of human mitochondria DNA types analyzed by restriction endonuclease cleavage patterns
-
Johnson M.J., Wallace D.C., Ferris S.D., Rattazzi M.C., and Cavalli-Sforza L.L. 1983. Radiation of human mitochondria DNA types analyzed by restriction endonuclease cleavage patterns. J. Mol. Evol. 19: 255.
-
(1983)
J. Mol. Evol.
, vol.19
, pp. 255
-
-
Johnson, M.J.1
Wallace, D.C.2
Ferris, S.D.3
Rattazzi, M.C.4
Cavalli-Sforza, L.L.5
-
38
-
-
0034866372
-
Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1
-
Kelley M.R. and Parsons S.H. 2001. Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1. Antioxid. Redox Signal. 3: 671.
-
(2001)
Antioxid. Redox Signal.
, vol.3
, pp. 671
-
-
Kelley, M.R.1
Parsons, S.H.2
-
39
-
-
0035925906
-
A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations
-
Khogali S.S., Mayosi B.M., Beattie J.M., McKenna W.J., Watkins H., and Poulton J. 2001. A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations. Lancet 357: 1265.
-
(2001)
Lancet
, vol.357
, pp. 1265
-
-
Khogali, S.S.1
Mayosi, B.M.2
Beattie, J.M.3
McKenna, W.J.4
Watkins, H.5
Poulton, J.6
-
40
-
-
0035882532
-
High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples
-
Kirches E., Krause G., Warich-Kirches M., Weis S., Schneider T., Meyer-Puttlitz B., Mawrin C., and Dietzmann K. 2001. High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples. Int. J. Cancer 93: 534.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 534
-
-
Kirches, E.1
Krause, G.2
Warich-Kirches, M.3
Weis, S.4
Schneider, T.5
Meyer-Puttlitz, B.6
Mawrin, C.7
Dietzmann, K.8
-
41
-
-
0842307483
-
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
-
Kokoszka J.E., Waymire K.G., Levy S.E., Sligh J.E., Cai J., Jones D.P., MacGregor G.R., and Wallace D.C. 2004. The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427: 461.
-
(2004)
Nature
, vol.427
, pp. 461
-
-
Kokoszka, J.E.1
Waymire, K.G.2
Levy, S.E.3
Sligh, J.E.4
Cai, J.5
Jones, D.P.6
MacGregor, G.R.7
Wallace, D.C.8
-
42
-
-
4444245853
-
Mitochondrial proteome: Cancer-altered metabolism associated with cytochrome c oxidase subunit level variation
-
Krieg R.C., Knuechel R., Schiffmann E., Liotta L.A., Petricoin E.F., III, and Herrmann P.C. 2004. Mitochondrial proteome: Cancer-altered metabolism associated with cytochrome c oxidase subunit level variation. Proteomics 4: 2789.
-
(2004)
Proteomics
, vol.4
, pp. 2789
-
-
Krieg, R.C.1
Knuechel, R.2
Schiffmann, E.3
Liotta, L.A.4
Petricoin III, E.F.5
Herrmann, P.C.6
-
43
-
-
22344456832
-
Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
-
Kujoth G.C., Hiona A., Pugh T.D., Someya S., Panzer K., Wohlgemuth S.E., Hofer T., Seo A.Y., Sullivan R., Jobling W.A., Morrow J.D., Van Remmen H., Sedivy J.M., Yamasoba T., Tanokura M., Weindruch R., Leeuwenburgh C., and Prolla T.A. 2005. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 309: 481.
-
(2005)
Science
, vol.309
, pp. 481
-
-
Kujoth, G.C.1
Hiona, A.2
Pugh, T.D.3
Someya, S.4
Panzer, K.5
Wohlgemuth, S.E.6
Hofer, T.7
Seo, A.Y.8
Sullivan, R.9
Jobling, W.A.10
Morrow, J.D.11
Van Remmen, H.12
Sedivy, J.M.13
Yamasoba, T.14
Tanokura, M.15
Weindruch, R.16
Leeuwenburgh, C.17
Prolla, T.A.18
-
44
-
-
4344570901
-
Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors
-
Kurtz A., Lueth M., Kluwe L., Zhang T., Foster R., Mautner V.F., Hartmann M., Tan D.J., Martuza R.L., Friedrich R.E., Driever P.H., and Wong L.J. 2004. Somatic mitochondrial DNA mutations in neurofibromatosis type 1-associated tumors. Mol. Cancer Res. 2: 433.
-
(2004)
Mol. Cancer Res.
, vol.2
, pp. 433
-
-
Kurtz, A.1
Lueth, M.2
Kluwe, L.3
Zhang, T.4
Foster, R.5
Mautner, V.F.6
Hartmann, M.7
Tan, D.J.8
Martuza, R.L.9
Friedrich, R.E.10
Driever, P.H.11
Wong, L.J.12
-
45
-
-
0026745033
-
Transcripts of the mitochondrial gene ND5 are overexpressed in highly metastatic murine large cell lymphoma cells
-
LaBiche R.A., Demars M., and Nicolson G.L. 1992. Transcripts of the mitochondrial gene ND5 are overexpressed in highly metastatic murine large cell lymphoma cells. In Vivo 6: 317.
-
(1992)
In Vivo
, vol.6
, pp. 317
-
-
LaBiche, R.A.1
Demars, M.2
Nicolson, G.L.3
-
46
-
-
0023927870
-
Gene expression and tumor cell escape from host effector mechanisms in murine large cell lymphoma
-
LaBiche R.A., Yoshida M., Gallick G.E., Irimura T., Robberson D.L., Klostergaard J., and Nicolson G.L. 1988. Gene expression and tumor cell escape from host effector mechanisms in murine large cell lymphoma. J. Cell. Biochem. 36: 393.
-
(1988)
J. Cell. Biochem.
, vol.36
, pp. 393
-
-
LaBiche, R.A.1
Yoshida, M.2
Gallick, G.E.3
Irimura, T.4
Robberson, D.L.5
Klostergaard, J.6
Nicolson, G.L.7
-
47
-
-
1542345767
-
Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma
-
Lee H.C., Li S.H., Lin J.C., Wu C.C., Yeh D.C., and Wei Y.H. 2004. Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma. Mutat. Res. 547: 71.
-
(2004)
Mutat. Res.
, vol.547
, pp. 71
-
-
Lee, H.C.1
Li, S.H.2
Lin, J.C.3
Wu, C.C.4
Yeh, D.C.5
Wei, Y.H.6
-
48
-
-
0142039877
-
Glucose metabolism in cancer: Importance of transcription factor-DNA interactions within a short segment of the proximal region of the type II hexokinase promoter
-
Lee M.G. and Pedersen P.L. 2003. Glucose metabolism in cancer: Importance of transcription factor-DNA interactions within a short segment of the proximal region of the type II hexokinase promoter. J. Biol. Chem. 278: 41047.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 41047
-
-
Lee, M.G.1
Pedersen, P.L.2
-
49
-
-
1542469716
-
Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors
-
Lehtonen R., Kiuru M., Vanharanta S., Sjoberg J., Aaltonen L.M., Aittomaki K., Arola J., Butzow R., Eng C., Husgafvel-Pursiainen K., Isola J., Jarvinen H., Koivisto P., Mecklin J.P., Peltomaki P., Salovaara R., Wasenius V.M., Karhu A., Launonen V., Nupponen N.N., and Aaltonen L.A. 2004. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. Am. J. Pathol. 164: 17.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 17
-
-
Lehtonen, R.1
Kiuru, M.2
Vanharanta, S.3
Sjoberg, J.4
Aaltonen, L.M.5
Aittomaki, K.6
Arola, J.7
Butzow, R.8
Eng, C.9
Husgafvel-Pursiainen, K.10
Isola, J.11
Jarvinen, H.12
Koivisto, P.13
Mecklin, J.P.14
Peltomaki, P.15
Salovaara, R.16
Wasenius, V.M.17
Karhu, A.18
Launonen, V.19
Nupponen, N.N.20
Aaltonen, L.A.21
more..
-
50
-
-
0035882029
-
High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas
-
Liu V.W., Shi H.H., Cheung A.N., Chiu P.M., Leung T.W., Nagley P., Wong L.C., and Ngan H.Y. 2001. High incidence of somatic mitochondrial DNA mutations in human ovarian carcinomas. Cancer Res. 61: 5998.
-
(2001)
Cancer Res.
, vol.61
, pp. 5998
-
-
Liu, V.W.1
Shi, H.H.2
Cheung, A.N.3
Chiu, P.M.4
Leung, T.W.5
Nagley, P.6
Wong, L.C.7
Ngan, H.Y.8
-
51
-
-
0041402740
-
Mitochondrial DNA variant 16189T>C is associated with susceptibility to endometrial cancer
-
Liu V.W., Wang Y., Yang H.J., Tsang P.C., Ng T.Y., Wong L.C., Nagley P., and Ngan H.Y. 2003. Mitochondrial DNA variant 16189T>C is associated with susceptibility to endometrial cancer. Hum. Mutat. 22: 173.
-
(2003)
Hum. Mutat.
, vol.22
, pp. 173
-
-
Liu, V.W.1
Wang, Y.2
Yang, H.J.3
Tsang, P.C.4
Ng, T.Y.5
Wong, L.C.6
Nagley, P.7
Ngan, H.Y.8
-
52
-
-
0347986675
-
Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases
-
Majewski N., Nogueira V., Robey R.B., and Hay N. 2004a. Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases. Mol. Cell. Biol. 24: 730.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 730
-
-
Majewski, N.1
Nogueira, V.2
Robey, R.B.3
Hay, N.4
-
53
-
-
9744221185
-
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
-
Majewski N., Nogueira V., Bhaskar P., Coy P.E., Skeen J.E., Gottlob K., Chandel N.S., Thompson C.B., Robey R.B., and Hay N. 2004b. Hexokinase- mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol. Cell 16: 819.
-
(2004)
Mol. Cell
, vol.16
, pp. 819
-
-
Majewski, N.1
Nogueira, V.2
Bhaskar, P.3
Coy, P.E.4
Skeen, J.E.5
Gottlob, K.6
Chandel, N.S.7
Thompson, C.B.8
Robey, R.B.9
Hay, N.10
-
54
-
-
0027282957
-
Dietary restriction and aging
-
Masoro E.J. 1993. Dietary restriction and aging. J. Am. Geriatr. Soc. 41: 994.
-
(1993)
J. Am. Geriatr. Soc.
, vol.41
, pp. 994
-
-
Masoro, E.J.1
-
55
-
-
0026526384
-
Dietary restriction alters characteristics of glucose fuel use
-
erratum in J. Gerontol. [1993] 48: B73
-
Masoro E.J., McCarter R.J., Katz M.S., and McMahan C.A. 1992. Dietary restriction alters characteristics of glucose fuel use (erratum in J. Gerontol. [1993] 48: B73). J. Gerontol. 47: B202.
-
(1992)
J. Gerontol.
, vol.47
-
-
Masoro, E.J.1
McCarter, R.J.2
Katz, M.S.3
McMahan, C.A.4
-
56
-
-
0030882879
-
Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53
-
Mathupala S.P., Heese C., and Pedersen P.L. 1997a. Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53. J. Biol. Chem. 272: 22776.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22776
-
-
Mathupala, S.P.1
Heese, C.2
Pedersen, P.L.3
-
57
-
-
0030665174
-
Aberrant glycolytic metabolism of cancer cells: A remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase
-
Mathupala S.P., Rempel A., and Pedersen P.L. 1997b. Aberrant glycolytic metabolism of cancer cells: A remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase. J. Bioenerg. Biomembr. 29: 339.
-
(1997)
J. Bioenerg. Biomembr.
, vol.29
, pp. 339
-
-
Mathupala, S.P.1
Rempel, A.2
Pedersen, P.L.3
-
58
-
-
0035900767
-
Glucose catabolism in cancer cells: Identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions
-
_. 2001. Glucose catabolism in cancer cells: Identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions. J. Biol. Chem. 276: 43407.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43407
-
-
-
59
-
-
1942453308
-
The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants
-
Mattiazzi M., Vijayvergiya C., Gajewski C.D., DeVivo D.C., Lenaz G., Wiedmann M., and Manfredi G. 2004. The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants. Hum. Mol. Genet. 13: 869.
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 869
-
-
Mattiazzi, M.1
Vijayvergiya, C.2
Gajewski, C.D.3
DeVivo, D.C.4
Lenaz, G.5
Wiedmann, M.6
Manfredi, G.7
-
60
-
-
0036095510
-
Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: A study with emphasis on Hurthle cell tumors
-
Maximo V., Soares P., Lima J., Cameselle-Teijeiro J., and Sobrinho-Simoes M. 2002. Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: A study with emphasis on Hurthle cell tumors. Am. J. Pathol. 160: 1857.
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1857
-
-
Maximo, V.1
Soares, P.2
Lima, J.3
Cameselle-Teijeiro, J.4
Sobrinho-Simoes, M.5
-
61
-
-
0026640250
-
Energy metabolism and aging: A lifelong study of Fischer 344 rats
-
McCarter R.J. and Palmer J. 1992. Energy metabolism and aging: A lifelong study of Fischer 344 rats. Am. J. Physiol. 263: E448.
-
(1992)
Am. J. Physiol.
, vol.263
-
-
McCarter, R.J.1
Palmer, J.2
-
62
-
-
0034213186
-
The evolution of free radicals and oxidative stress
-
McCord J.M. 2000. The evolution of free radicals and oxidative stress. Am. J. Med. Genet. 108: 652.
-
(2000)
Am. J. Med. Genet.
, vol.108
, pp. 652
-
-
McCord, J.M.1
-
63
-
-
0034284973
-
Extension of life-span with superoxide dismutase/catalase mimetics
-
Melov S., Ravenscroft J., Malik S., Gill M.S., Walker D.W., Clayton P.E., Wallace D.C., Malfroy B., Doctrow S.R., and Lithgow G.J. 2000. Extension of life-span with superoxide dismutase/catalase mimetics. Science 289: 1567.
-
(2000)
Science
, vol.289
, pp. 1567
-
-
Melov, S.1
Ravenscroft, J.2
Malik, S.3
Gill, M.S.4
Walker, D.W.5
Clayton, P.E.6
Wallace, D.C.7
Malfroy, B.8
Doctrow, S.R.9
Lithgow, G.J.10
-
64
-
-
0026340064
-
The structure of human mitochondrial DNA variation
-
Merriwether D.A., Clark A.G., Ballinger S.W., Schurr T.G., Soodyall H., Jenkins T., Sherry S.T., and Wallace D.C. 1991. The structure of human mitochondrial DNA variation. J. Mol. Evol. 33: 543.
-
(1991)
J. Mol. Evol.
, vol.33
, pp. 543
-
-
Merriwether, D.A.1
Clark, A.G.2
Ballinger, S.W.3
Schurr, T.G.4
Soodyall, H.5
Jenkins, T.6
Sherry, S.T.7
Wallace, D.C.8
-
65
-
-
0037422550
-
Natural selection shaped regional mtDNA variation in humans
-
Mishmar D., Ruiz-Pesini E.E., Golik P., Macaulay V., Clark A.G., Hosseini S., Brandon M., Easley K., Chen E., Brown M.D., Sukernik R.I., Olckers A., and Wallace D.C. 2003. Natural selection shaped regional mtDNA variation in humans. Proc. Natl. Acad. Sci. 100: 171.
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 171
-
-
Mishmar, D.1
Ruiz-Pesini, E.E.2
Golik, P.3
Macaulay, V.4
Clark, A.G.5
Hosseini, S.6
Brandon, M.7
Easley, K.8
Chen, E.9
Brown, M.D.10
Sukernik, R.I.11
Olckers, A.12
Wallace, D.C.13
-
66
-
-
0033767445
-
Mutations in SDHC cause autosomal dominant paraganglioma, type 3
-
Niemann S. and Muller U. 2000. Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nat. Genet. 26: 268.
-
(2000)
Nat. Genet.
, vol.26
, pp. 268
-
-
Niemann, S.1
Muller, U.2
-
67
-
-
0036187963
-
Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma
-
Nomoto S., Yamashita K., Koshikawa K., Nakao A., and Sidransky D. 2002. Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma. Clin. Cancer Res. 8: 481.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 481
-
-
Nomoto, S.1
Yamashita, K.2
Koshikawa, K.3
Nakao, A.4
Sidransky, D.5
-
68
-
-
0035886843
-
Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates
-
Parrella P., Xiao Y., Fliss M., Sanchez-Cespedes M., Mazzarelli P., Rinaldi M., Nicol T., Gabrielson E., Cuomo C., Cohen D., Pandit S., Spencer M., Rabitti C., Fazio V.M., and Sidransky D. 2001. Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. Cancer Res. 61: 7623.
-
(2001)
Cancer Res.
, vol.61
, pp. 7623
-
-
Parrella, P.1
Xiao, Y.2
Fliss, M.3
Sanchez-Cespedes, M.4
Mazzarelli, P.5
Rinaldi, M.6
Nicol, T.7
Gabrielson, E.8
Cuomo, C.9
Cohen, D.10
Pandit, S.11
Spencer, M.12
Rabitti, C.13
Fazio, V.M.14
Sidransky, D.15
-
69
-
-
0017841405
-
Tumor mitochondria and the bioenergetics of cancer cells
-
Pedersen P.L. 1978. Tumor mitochondria and the bioenergetics of cancer cells. Prog. Exp. Tumor Res. 22: 190.
-
(1978)
Prog. Exp. Tumor Res.
, vol.22
, pp. 190
-
-
Pedersen, P.L.1
-
70
-
-
0037056002
-
Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
-
Pedersen P.L., Mathupala S., Rempel A., Geschwind J.F., and Ko Y.H. 2002. Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim. Biophys. Acta 1555: 14.
-
(2002)
Biochim. Biophys. Acta
, vol.1555
, pp. 14
-
-
Pedersen, P.L.1
Mathupala, S.2
Rempel, A.3
Geschwind, J.F.4
Ko, Y.H.5
-
71
-
-
20044364344
-
mtDNA mutations increase tumorigenicity in prostate cancer
-
Petros J.A., Baumann A.K., Ruiz-Pesini E., Amin M.B., Sun C.Q., Hall J., Lim S., Issa M.M., Flanders W.D., Hosseini S.H., Marshall F.F., and Wallace D.C. 2005. mtDNA mutations increase tumorigenicity in prostate cancer. Proc. Natl. Acad. Sci. 102: 719.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 719
-
-
Petros, J.A.1
Baumann, A.K.2
Ruiz-Pesini, E.3
Amin, M.B.4
Sun, C.Q.5
Hall, J.6
Lim, S.7
Issa, M.M.8
Flanders, W.D.9
Hosseini, S.H.10
Marshall, F.F.11
Wallace, D.C.12
-
72
-
-
0031736203
-
Somatic mutations of the mitochondrial genome in human colorectal tumours
-
Polyak K., Li Y., Zhu H., Lengauer C., Willson J.K., Markowitz S.D., Trush M.A., Kinzler K.W., and Vogelstein B. 1998. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat. Genet. 20: 291.
-
(1998)
Nat. Genet.
, vol.20
, pp. 291
-
-
Polyak, K.1
Li, Y.2
Zhu, H.3
Lengauer, C.4
Willson, J.K.5
Markowitz, S.D.6
Trush, M.A.7
Kinzler, K.W.8
Vogelstein, B.9
-
73
-
-
0031731693
-
Does a common mitochondrial DNA polymorphism underlie susceptibility to diabetes and the thrifty genotype?
-
Poulton J. 1998. Does a common mitochondrial DNA polymorphism underlie susceptibility to diabetes and the thrifty genotype? Trends Genet. 14: 387.
-
(1998)
Trends Genet.
, vol.14
, pp. 387
-
-
Poulton, J.1
-
74
-
-
15644370476
-
A common mitochondrial DNA variant is associated with insulin resistance in adult life
-
Poulton J., Brown M.S., Cooper A., Marchington D.R., and Phillips D.I. 1998. A common mitochondrial DNA variant is associated with insulin resistance in adult life. Diabetologia 41: 54.
-
(1998)
Diabetologia
, vol.41
, pp. 54
-
-
Poulton, J.1
Brown, M.S.2
Cooper, A.3
Marchington, D.R.4
Phillips, D.I.5
-
75
-
-
0347356538
-
Effects of purifying and adaptive selection on regional variation in human mtDNA
-
Ruiz-Pesini E., Mishmar D., Brandon M., Procaccio V., and Wallace D.C. 2004. Effects of purifying and adaptive selection on regional variation in human mtDNA. Science 303: 223.
-
(2004)
Science
, vol.303
, pp. 223
-
-
Ruiz-Pesini, E.1
Mishmar, D.2
Brandon, M.3
Procaccio, V.4
Wallace, D.C.5
-
76
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to the mitochondria
-
Schriner S.E., Linford N.J., Martin G.M., Treuting P., Ogburn C.E., Emond M., Coskun P.E., Ladiges W., Wolf N., Van Remmen H., Wallace D.C., and Rabinovitch P.S. 2005. Extension of murine life span by overexpression of catalase targeted to the mitochondria. Science 308: 1909.
-
(2005)
Science
, vol.308
, pp. 1909
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
Wallace, D.C.11
Rabinovitch, P.S.12
-
77
-
-
0035834789
-
A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans
-
Senoo-Matsuda N., Yasuda K., Tsuda M., Ohkubo T., Yoshimura S., Nakazawa H., Hartman P.S., and Ishii N. 2001. A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans. J. Biol. Chem. 276: 41553.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41553
-
-
Senoo-Matsuda, N.1
Yasuda, K.2
Tsuda, M.3
Ohkubo, T.4
Yoshimura, S.5
Nakazawa, H.6
Hartman, P.S.7
Ishii, N.8
-
78
-
-
0025368281
-
Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation
-
Shoffner J.M., Lott M.T., Lezza A.M., Seibel P., Ballinger S.W., and Wallace D.C. 1990. Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation. Cell 61: 931.
-
(1990)
Cell
, vol.61
, pp. 931
-
-
Shoffner, J.M.1
Lott, M.T.2
Lezza, A.M.3
Seibel, P.4
Ballinger, S.W.5
Wallace, D.C.6
-
79
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
-
Sohal R.S., Ku H.H., Agarwal S., Forster M.J., and Lal H. 1994. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech. Ageing Dev. 74: 121.
-
(1994)
Mech. Ageing Dev.
, vol.74
, pp. 121
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
80
-
-
0021111828
-
Tumor-associated mutations of rat mitochondrial transfer RNA genes
-
Taira M., Yoshida E., Kobayashi M., Yaginuma K., and Koike K. 1983. Tumor-associated mutations of rat mitochondrial transfer RNA genes. Nucleic Acids Res. 11: 1635.
-
(1983)
Nucleic Acids Res.
, vol.11
, pp. 1635
-
-
Taira, M.1
Yoshida, E.2
Kobayashi, M.3
Yaginuma, K.4
Koike, K.5
-
81
-
-
0035949699
-
AKT plays a central role in tumorigenesis
-
Testa J.R. and Bellacosa A. 2001. AKT plays a central role in tumorigenesis. Proc. Natl. Acad. Sci. 98: 10983.
-
(2001)
Proc. Natl. Acad. Sci.
, vol.98
, pp. 10983
-
-
Testa, J.R.1
Bellacosa, A.2
-
82
-
-
0037373797
-
Mitochondrial DNA alterations in thyroid cancer
-
Tong B.C., Ha P.K., Dhir K., Xing M., Westra W.H., Sidransky D., and Califano J.A. 2003. Mitochondrial DNA alterations in thyroid cancer. J. Surg. Oncol. 82: 170.
-
(2003)
J. Surg. Oncol.
, vol.82
, pp. 170
-
-
Tong, B.C.1
Ha, P.K.2
Dhir, K.3
Xing, M.4
Westra, W.H.5
Sidransky, D.6
Califano, J.A.7
-
83
-
-
0025243540
-
Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes
-
Torroni A., Stepien G., Hodge J.A., and Wallace D.C. 1990. Neoplastic transformation is associated with coordinate induction of nuclear and cytoplasmic oxidative phosphorylation genes. J. Biol. Chem. 265: 20589.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 20589
-
-
Torroni, A.1
Stepien, G.2
Hodge, J.A.3
Wallace, D.C.4
-
84
-
-
0028095263
-
MtDNA and the origin of Caucasians. Identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region
-
Torroni A., Lott M.T., Cabell M.F., Chen Y., Laverge L., and Wallace D.C. 1994. MtDNA and the origin of Caucasians. Identification of ancient Caucasian-specific haplogroups, one of which is prone to a recurrent somatic duplication in the D-loop region. Am. J. Hum. Genet. 55: 760.
-
(1994)
Am. J. Hum. Genet.
, vol.55
, pp. 760
-
-
Torroni, A.1
Lott, M.T.2
Cabell, M.F.3
Chen, Y.4
Laverge, L.5
Wallace, D.C.6
-
85
-
-
2642580016
-
Premature ageing in mice expressing defective mitochondrial DNA polymerase
-
Trifunovic A., Wredenberg A., Falkenberg M., Spelbrink J.N., Rovio A.T., Bruder C.E., Bohlooly Y.M., Gidlof S., Oldfors A., Wibom R., Tornell J., Jacobs H.T., and Larsson N.G. 2004. Premature ageing in mice expressing defective mitochondrial DNA polymerase. Nature 429: 417.
-
(2004)
Nature
, vol.429
, pp. 417
-
-
Trifunovic, A.1
Wredenberg, A.2
Falkenberg, M.3
Spelbrink, J.N.4
Rovio, A.T.5
Bruder, C.E.6
Bohlooly, Y.M.7
Gidlof, S.8
Oldfors, A.9
Wibom, R.10
Tornell, J.11
Jacobs, H.T.12
Larsson, N.G.13
-
86
-
-
0027936218
-
Cytoplasmic transfer of the mtDNA nt 8993 TG (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio
-
Trounce I., Neill S., and Wallace D.C. 1994. Cytoplasmic transfer of the mtDNA nt 8993 TG (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio. Proc. Natl. Acad. Sci. 91: 8334.
-
(1994)
Proc. Natl. Acad. Sci.
, vol.91
, pp. 8334
-
-
Trounce, I.1
Neill, S.2
Wallace, D.C.3
-
87
-
-
4244110904
-
0 cultured cells
-
0 cultured cells. Am. J. Hum. Genet. 57: A252.
-
(1995)
Am. J. Hum. Genet.
, vol.57
-
-
-
88
-
-
0029964226
-
Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines
-
Trounce I.A., Kim Y.L., Jun A.S., and Wallace D.C. 1996. Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines. Methods Enzymol. 264: 484.
-
(1996)
Methods Enzymol.
, vol.264
, pp. 484
-
-
Trounce, I.A.1
Kim, Y.L.2
Jun, A.S.3
Wallace, D.C.4
-
89
-
-
12144288373
-
Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging
-
Van Remmen H., Ikeno Y., Hamilton M., Pahlavani M., Wolf N., Thorpe S.R., Alderson N.L., Baynes J.W., Epstein C.J., Huang T.T., Nelson J., Strong R., and Richardson A. 2003. Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. Physiol. Genomics 16: 29.
-
(2003)
Physiol. Genomics
, vol.16
, pp. 29
-
-
Van Remmen, H.1
Ikeno, Y.2
Hamilton, M.3
Pahlavani, M.4
Wolf, N.5
Thorpe, S.R.6
Alderson, N.L.7
Baynes, J.W.8
Epstein, C.J.9
Huang, T.T.10
Nelson, J.11
Strong, R.12
Richardson, A.13
-
90
-
-
9144249602
-
Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma
-
Vanharanta S., Buchta M., McWhinney S.R., Virta S.K., Peczkowska M., Morrison C.D., Lehtonen R., Januszewicz A., Jarvinen H., Juhola M., Mecklin J.P., Pukkala E., Herva R., Kiuru M., Nupponen N.N., Aaltonen L.A., Neumann H.P., and Eng C. 2004. Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma. Am. J. Hum. Genet. 74: 153.
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 153
-
-
Vanharanta, S.1
Buchta, M.2
McWhinney, S.R.3
Virta, S.K.4
Peczkowska, M.5
Morrison, C.D.6
Lehtonen, R.7
Januszewicz, A.8
Jarvinen, H.9
Juhola, M.10
Mecklin, J.P.11
Pukkala, E.12
Herva, R.13
Kiuru, M.14
Nupponen, N.N.15
Aaltonen, L.A.16
Neumann, H.P.17
Eng, C.18
-
91
-
-
0026587335
-
Mitochondrial genetics: A paradigm for aging and degenerative diseases?
-
Wallace D.C. 1992. Mitochondrial genetics: A paradigm for aging and degenerative diseases? Science 256: 628.
-
(1992)
Science
, vol.256
, pp. 628
-
-
Wallace, D.C.1
-
92
-
-
23844558266
-
A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine
-
_. 2005. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: A dawn for evolutionary medicine. Annu. Rev. Genet. 39: 359.
-
(2005)
Annu. Rev. Genet.
, vol.39
, pp. 359
-
-
-
93
-
-
13444271415
-
Mitochondrial genes in degenerative diseases, cancer and aging
-
(ed. D.L. Rimoin et al.), Churchill Livingstone, London, United Kingdom
-
Wallace D.C. and Lott M.T. 2002. Mitochondrial genes in degenerative diseases, cancer and aging. In Emery and Rimoin's principles and practice of medical genetics (ed. D.L. Rimoin et al.), p. 299. Churchill Livingstone, London, United Kingdom.
-
(2002)
Emery and Rimoin's Principles and Practice of Medical Genetics
, pp. 299
-
-
Wallace, D.C.1
Lott, M.T.2
-
94
-
-
0032833421
-
Mitochondrial DNA variation in human evolution and disease
-
Wallace D.C., Brown M.D., and Lott M.T. 1999. Mitochondrial DNA variation in human evolution and disease. Gene 238: 211.
-
(1999)
Gene
, vol.238
, pp. 211
-
-
Wallace, D.C.1
Brown, M.D.2
Lott, M.T.3
-
95
-
-
0024242545
-
Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy
-
Wallace D.C., Singh G., Lott M.T., Hodge J.A., Schurr T.G., Lezza A.M., Elsas L.J., and Nikoskelainen E.K. 1988a. Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy. Science 242: 1427.
-
(1988)
Science
, vol.242
, pp. 1427
-
-
Wallace, D.C.1
Singh, G.2
Lott, M.T.3
Hodge, J.A.4
Schurr, T.G.5
Lezza, A.M.6
Elsas, L.J.7
Nikoskelainen, E.K.8
-
96
-
-
0024163051
-
Familial mitochondrial encephalomyopathy (MERRF): Genetic, pathophysiological, and biochemical characterization of a mitochondrial DNA disease
-
Wallace D.C., Zheng X., Lott M.T., Shoffner J.M., Hodge J.A., Kelley R.I., Epstein C.M., and Hopkins L.C. 1988b. Familial mitochondrial encephalomyopathy (MERRF): Genetic, pathophysiological, and biochemical characterization of a mitochondrial DNA disease. Cell 55: 601.
-
(1988)
Cell
, vol.55
, pp. 601
-
-
Wallace, D.C.1
Zheng, X.2
Lott, M.T.3
Shoffner, J.M.4
Hodge, J.A.5
Kelley, R.I.6
Epstein, C.M.7
Hopkins, L.C.8
-
98
-
-
23044514580
-
Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer
-
Wu C.W., Yin P.H., Hung W.Y., Li A.F., Li S.H., Chi C.W., Wei Y.H., and Lee H.C. 2005. Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer. Genes Chromosomes Cancer 44: 19.
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 19
-
-
Wu, C.W.1
Yin, P.H.2
Hung, W.Y.3
Li, A.F.4
Li, S.H.5
Chi, C.W.6
Wei, Y.H.7
Lee, H.C.8
-
99
-
-
0033531247
-
Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells
-
Xu Y., Krishnan A., Wan X.S., Majima H., Yeh C.C., Ludewig G., Kasarskis E.J., and St. Clair D.K. 1999. Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells. Oncogene 18: 93.
-
(1999)
Oncogene
, vol.18
, pp. 93
-
-
Xu, Y.1
Krishnan, A.2
Wan, X.S.3
Majima, H.4
Yeh, C.C.5
Ludewig, G.6
Kasarskis, E.J.7
St. Clair, D.K.8
-
100
-
-
0032573066
-
Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
-
Yan L.J. and Sohal R.S. 1998. Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc. Natl. Acad. Sci. 95: 12896.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 12896
-
-
Yan, L.J.1
Sohal, R.S.2
-
101
-
-
27144435807
-
Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs
-
Yanagihara M., Katano M., Takahashi-Sasaki N., Kimata K., Taira K., and Andoh T. 2005. Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs. Cancer Sci. 96: 620.
-
(2005)
Cancer Sci.
, vol.96
, pp. 620
-
-
Yanagihara, M.1
Katano, M.2
Takahashi-Sasaki, N.3
Kimata, K.4
Taira, K.5
Andoh, T.6
-
102
-
-
0034643388
-
Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours
-
Yeh J.J., Lunetta K.L., van Orsouw N.J., Moore F.D., Jr., Mutter G.L., Vijg J., Dahia P.L., and Eng C. 2000. Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene 19: 2060.
-
(2000)
Oncogene
, vol.19
, pp. 2060
-
-
Yeh, J.J.1
Lunetta, K.L.2
Van Orsouw, N.J.3
Moore Jr., F.D.4
Mutter, G.L.5
Vijg, J.6
Dahia, P.L.7
Eng, C.8
-
103
-
-
13244255428
-
Nucleotide sequence variation is frequent in the mitochondrial DNA displacement loop region of individual human tumor cells
-
Yoneyama H., Hara T., Kato Y., Yamori T., Matsuura E.T., and Koike K. 2005. Nucleotide sequence variation is frequent in the mitochondrial DNA displacement loop region of individual human tumor cells. Mol. Cancer Res. 3: 14.
-
(2005)
Mol. Cancer Res.
, vol.3
, pp. 14
-
-
Yoneyama, H.1
Hara, T.2
Kato, Y.3
Yamori, T.4
Matsuura, E.T.5
Koike, K.6
|