Pertussis toxin potentiates T(h)1 and T(h)2 responses to co-injected antigen: Adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28

International Immunology

Volumn 10, Issue 5, 1998, Pages 651-662

  Ryan, Mark ^a   McCarthy, Leone ^a   Rappuoll, Rino ^b   Mahon, Bernard P ^a   Mills, Kingston H G ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b CHIRON VACCINES   (Italy)

Author keywords

Antigen presentation; Bacteria; IFN ; IL 1; IL 12; IL 2; IL 4; IL 5; Immunomodulator; Infectious disease; Pertussis vaccine; T cell activation

Indexed keywords

ANTIGEN; CD28 ANTIGEN; GAMMA INTERFERON; HLA B7 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN 1; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PERTUSSIS TOXIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; ENZYME ACTIVITY; HELPER CELL; IMMUNE SYSTEM; IMMUNOGLOBULIN PRODUCTION; IMMUNOPOTENTIATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BINDING; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS; ANTIGENS, CD; ANTIGENS, CD28; ANTIGENS, CD80; ANTIGENS, CD86; B-LYMPHOCYTES; CYTOKINES; DRUG SYNERGISM; INTERLEUKIN-1; INTERLEUKIN-12; LYMPHOCYTE ACTIVATION; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PERTUSSIS TOXIN; TH1 CELLS; TH2 CELLS; VIRULENCE FACTORS, BORDETELLA;

EID: 0031920860     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.5.651     Document Type: Article

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