Primary role for Gi protein signaling in the regulation of interleukin 12 production and the induction of T helper cell type 1 responses

Journal of Experimental Medicine

Volumn 191, Issue 9, 2000, Pages 1605-1610

  He, Jianping ^a   Gurunathan, Sanjay ^a   Iwasaki, Akiko ^a   Ash Shaheed, Belinda ^a   Kelsall, Brian L ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

G protein; Interleukin 12; Leishmaniasis; Pertussis toxin; T helper cell type 1

Indexed keywords

CD8 ANTIGEN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; PERTUSSIS TOXIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; FEMALE; HEALING; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN CELL; TH1 CELL;

ADENOSINE DIPHOSPHATE RIBOSE; ANIMALS; ANTIGENS, CD8; CELL DIFFERENTIATION; DENDRITIC CELLS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-4; LEISHMANIASIS, CUTANEOUS; LYMPH NODES; MICE; MICE, INBRED BALB C; MICE, MUTANT STRAINS; PERTUSSIS TOXIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIGNAL TRANSDUCTION; SPLEEN; TH1 CELLS; TUMOR NECROSIS FACTOR-ALPHA; VIRULENCE FACTORS, BORDETELLA;

EID: 0034193331     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.191.9.1605     Document Type: Article

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