The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-α in 3T3-L1 adipocytes and is a target for transactivation by PPARγ

American Journal of Physiology - Endocrinology and Metabolism

Volumn 291, Issue 1, 2006, Pages

  Ji, Young Kim ^a   Tillison, Kristin ^a   Lee, Jun Ho ^a   Rearick, David A ^a   Smas, Cynthia M ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

Adipogenesis; Gene regulation; Patatin like phospholipase domain containing 2; Peroxisome proliferator activated receptor ; Promoter activity; Tumor necrosis factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; INSULIN; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN P70; RAPAMYCIN; S6 KINASE; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ENERGY BALANCE; ENZYME REGULATION; GENE CONTROL; GENE STRUCTURE; HORMONAL REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TRANSACTIVATION; TRANSCRIPTION INITIATION;

3T3-L1 CELLS; ADIPOCYTES; ADIPOSE TISSUE; ANIMALS; BLOTTING, NORTHERN; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INSULIN; LIPASE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NZB; MICE, OBESE; MICROSCOPY, FLUORESCENCE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745849713     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00317.2005     Document Type: Article

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