메뉴 건너뛰기




Volumn 9, Issue 2, 2001, Pages 119-128

The adipose tissue phenotype of hormone-sensitive lipase deficiency in mice

Author keywords

Brown adipose tissue; Hormone sensitive lipase; Knockout mice; Lipolysis; Thermogenesis

Indexed keywords

CHOLESTEROL ESTERASE; MESSENGER RNA;

EID: 0035257508     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2001.15     Document Type: Article
Times cited : (199)

References (44)
  • 1
    • 0032560615 scopus 로고    scopus 로고
    • Mutational analysis of structural features of rat hormone-sensitive lipase
    • Shen W-J, Patel S, Natu V, et al. Mutational analysis of structural features of rat hormone-sensitive lipase. Biochemistry. 1998;37:8973-9.
    • (1998) Biochemistry , vol.37 , pp. 8973-8979
    • Shen, W.-J.1    Patel, S.2    Natu, V.3
  • 2
    • 2642614548 scopus 로고    scopus 로고
    • Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro
    • Anthonsen MW, Rönnstrand L, Wernstedt C, Identification of novel phosphorylation sites in hormone-sensitive lipase that are phosphorylated in response to isoproterenol and govern activation properties in vitro. J Biol Chem. 1998;273:215-21.
    • (1998) J Biol Chem. , vol.273 , pp. 215-221
    • Anthonsen, M.W.1    Rönnstrand, L.2    Wernstedt, C.3
  • 3
    • 0026783771 scopus 로고
    • Mechanism of hormone-stimulated lipolysis in adipocytes: Translocation of hormone-sensitive lipase to the lipid storage droplet
    • Egan JJ, Greenberg AS, Chang MK, et al. Mechanism of hormone-stimulated lipolysis in adipocytes: translocation of hormone-sensitive lipase to the lipid storage droplet. Proc Natl Acad Sci USA. 1992;89:8537-41.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8537-8541
    • Egan, J.J.1    Greenberg, A.S.2    Chang, M.K.3
  • 4
    • 0033071156 scopus 로고    scopus 로고
    • Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells
    • Londos C, Brasaemlet DL, Schultz CJ, et al. Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Cell Dev Biol. 1999;10:51-8.
    • (1999) Cell Dev Biol. , vol.10 , pp. 51-58
    • Londos, C.1    Brasaemlet, D.L.2    Schultz, C.J.3
  • 5
    • 0033165872 scopus 로고    scopus 로고
    • Lipotransin: A novel docking protein for hormone-sensitive lipase
    • Syu L-J, Saltiel AR. Lipotransin: a novel docking protein for hormone-sensitive lipase. Mol Cell. 1999;4:109-15.
    • (1999) Mol Cell. , vol.4 , pp. 109-115
    • Syu, L.-J.1    Saltiel, A.R.2
  • 6
    • 0027198857 scopus 로고
    • Gene organization and primary structure of human hormone-sensitive lipase: Possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium
    • Langin D, Laurell H, Holst LS, et al. Gene organization and primary structure of human hormone-sensitive lipase: possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium. Proc Natl Acad Sci USA. 1993;90:4897-901.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4897-4901
    • Langin, D.1    Laurell, H.2    Holst, L.S.3
  • 7
    • 0031063193 scopus 로고    scopus 로고
    • Hormone-sensitive lipase (Lipe). Sequence analysis of the 129sv mouse Lipe gene
    • Sztrolovics R, Wang SP, Lapierre P, et al. Hormone-sensitive lipase (Lipe). Sequence analysis of the 129Sv mouse Lipe gene. Mamm Genome. 1997;8:86-9.
    • (1997) Mamm Genome. , vol.8 , pp. 86-89
    • Sztrolovics, R.1    Wang, S.P.2    Lapierre, P.3
  • 8
    • 0028574264 scopus 로고
    • Isolation and characterization of the gene for mouse hormone-sensitive lipase
    • Li Z, Sumida M, Birchbauer A, et al. Isolation and characterization of the gene for mouse hormone-sensitive lipase. Genomics. 1994;24:259-65.
    • (1994) Genomics , vol.24 , pp. 259-265
    • Li, Z.1    Sumida, M.2    Birchbauer, A.3
  • 9
    • 0023795353 scopus 로고
    • Hormone-sensitive lipase: Sequence, expression, and chromosomal localization to 19 cent-q13.3
    • Holm C, Kirchgessner TG, Svenson KL, et al. Hormone-sensitive lipase: sequence, expression, and chromosomal localization to 19 cent-q13.3. Science. 1988;241:1503-6.
    • (1988) Science , vol.241 , pp. 1503-1506
    • Holm, C.1    Kirchgessner, T.G.2    Svenson, K.L.3
  • 10
    • 0027261299 scopus 로고
    • Chromosomal localization of lipolytic enzymes in the mouse: Pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase
    • Warden CH, Davis RC, Yoon MY, et al. Chromosomal localization of lipolytic enzymes in the mouse: pancreatic lipase, colipase, hormone-sensitive lipase, hepatic lipase, and carboxyl ester lipase. J Lipid Res. 1993;34:1451-5.
    • (1993) J Lipid Res. , vol.34 , pp. 1451-1455
    • Warden, C.H.1    Davis, R.C.2    Yoon, M.Y.3
  • 11
    • 0028557457 scopus 로고
    • Hormone-sensitive lipase maps to proximal chromosome 7 in mice and is genetically distinct from the ad and tub loci
    • Wang S, Lapierre P, Robert M-F, et al. Hormone-sensitive lipase maps to proximal chromosome 7 in mice and is genetically distinct from the ad and tub loci. Genomics. 1994;24:416-7.
    • (1994) Genomics , vol.24 , pp. 416-417
    • Wang, S.1    Lapierre, P.2    Robert, M.-F.3
  • 12
    • 0030093040 scopus 로고    scopus 로고
    • Adipocyte hormone-sensitive lipase: A major regulator of lipid metabolism
    • Langin D, Holm C, Lafontan M. Adipocyte hormone-sensitive lipase: a major regulator of lipid metabolism. Proc Nutr Soc. 1996;55:93-109.
    • (1996) Proc Nutr Soc. , vol.55 , pp. 93-109
    • Langin, D.1    Holm, C.2    Lafontan, M.3
  • 13
    • 0027413273 scopus 로고
    • Detection of hormone-sensitive lipase in various tissues. I. Expression of an Hsl/bacterial fusion protein and generation of anti-HSL antibodies
    • Kraemer FB, Patel S, Saedi MS, et al. Detection of hormone-sensitive lipase in various tissues. I. Expression of an HSL/bacterial fusion protein and generation of anti-HSL antibodies. J Lipid Res. 1993;34:663-71.
    • (1993) J Lipid Res. , vol.34 , pp. 663-671
    • Kraemer, F.B.1    Patel, S.2    Saedi, M.S.3
  • 14
    • 0027489939 scopus 로고
    • Expression of hormone-sensitive lipase mRNA in macrophages
    • Khoo JC, Reue K, Steinberg D, Expression of hormone-sensitive lipase mRNA in macrophages. J Lipid Res. 1993;34: 1969-74.
    • (1993) J Lipid Res. , vol.34 , pp. 1969-1974
    • Khoo, J.C.1    Reue, K.2    Steinberg, D.3
  • 15
    • 0031458386 scopus 로고    scopus 로고
    • Evidence for hormone-sensitive lipase mRNA expression in human monocyte/macrophages
    • Reue K, Cohen RD, Schotz MC. Evidence for hormone-sensitive lipase mRNA expression in human monocyte/macrophages. Arterioscler Thromb Vasc Biol. 1997;17:3428-32.
    • (1997) Arterioscler Thromb Vasc Biol. , vol.17 , pp. 3428-3432
    • Reue, K.1    Cohen, R.D.2    Schotz, M.C.3
  • 16
    • 0032933607 scopus 로고    scopus 로고
    • Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in β-cells
    • Mulder H, Holst LS, Svensson H, et al. Hormone-sensitive lipase, the rate-limiting enzyme in triglyceride hydrolysis, is expressed and active in β-cells. Diabetes. 1999;48:228-32.
    • (1999) Diabetes , vol.48 , pp. 228-232
    • Mulder, H.1    Holst, L.S.2    Svensson, H.3
  • 17
    • 0033515537 scopus 로고    scopus 로고
    • Testis expression of hormone-sensitive lipase is conferred by a specific promoter that contains four regins binding testicular nuclear proteins
    • Blaise R, Grober J, Rouet P, et al. Testis expression of hormone-sensitive lipase is conferred by a specific promoter that contains four regins binding testicular nuclear proteins. J Biol Chem. 1999;274:9327-34.
    • (1999) J Biol Chem. , vol.274 , pp. 9327-9334
    • Blaise, R.1    Grober, J.2    Rouet, P.3
  • 18
    • 0000537214 scopus 로고    scopus 로고
    • Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase
    • Holst LS, Langin D, Mulder H, et al. Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase. Genomics. 1996;35:441-7.
    • (1996) Genomics , vol.35 , pp. 441-447
    • Holst, L.S.1    Langin, D.2    Mulder, H.3
  • 19
    • 0032608438 scopus 로고    scopus 로고
    • Hormone-sensitive lipase and neutral cholesteryl ester lipase
    • Holm C, Osterlund T. Hormone-sensitive lipase and neutral cholesteryl ester lipase. Methods Mol Biol. 1999;109:109-21.
    • (1999) Methods Mol Biol. , vol.109 , pp. 109-121
    • Holm, C.1    Osterlund, T.2
  • 20
    • 0030983554 scopus 로고    scopus 로고
    • Retinyl ester hydrolysis and retinol efflux from BFC-1β adipocytes
    • Wei S, Lai K, Patel S, et al. Retinyl ester hydrolysis and retinol efflux from BFC-1β adipocytes. J Biol Chem. 1997; 272:14159-65.
    • (1997) J Biol Chem. , vol.272 , pp. 14159-14165
    • Wei, S.1    Lai, K.2    Patel, S.3
  • 21
    • 0023700741 scopus 로고
    • Hormone-sensitive lipase is involved in the hydrolysis of lipoidal derivatives of estrogens and other steroid hormones
    • Lee FT, Adams JB, Garton AJ, et al. Hormone-sensitive lipase is involved in the hydrolysis of lipoidal derivatives of estrogens and other steroid hormones. Biochim Biophys Acta. 1988;963:258-64.
    • (1988) Biochim Biophys Acta. , vol.963 , pp. 258-264
    • Lee, F.T.1    Adams, J.B.2    Garton, A.J.3
  • 22
    • 0028274779 scopus 로고
    • Regulation of hormone-sensitive lipase during fasting
    • Sztalryd C, Kraemer FB. Regulation of hormone-sensitive lipase during fasting. Am J Physiol. 1994;266:E179-85.
    • (1994) Am J Physiol. , vol.266
    • Sztalryd, C.1    Kraemer, F.B.2
  • 23
    • 8044237718 scopus 로고    scopus 로고
    • Adipose tissue lipolysis and hormone-sensitive lipase expression during very-low-calorie diet in obese female identical twins
    • Stich V, Harant I, De Glisezinski I, et al. Adipose tissue lipolysis and hormone-sensitive lipase expression during very-low-calorie diet in obese female identical twins. J Clin Endocrinol Metab. 1997;82:739-44.
    • (1997) J Clin Endocrinol Metab. , vol.82 , pp. 739-744
    • Stich, V.1    Harant, I.2    Glisezinski D. I3
  • 24
    • 0028242235 scopus 로고
    • Lipoprotein lipase and hormone-sensitive lipase activity and mRNA in rat adipose tissue during pregnancy
    • Martin-Hidalgo A, Holm C, Belfrage P, et al. Lipoprotein lipase and hormone-sensitive lipase activity and mRNA in rat adipose tissue during pregnancy. Am J Physiol. 1994;266: E930-5.
    • (1994) Am J Physiol. , vol.266
    • Martin-Hidalgo, A.1    Holm, C.2    Belfrage, P.3
  • 25
    • 0026538804 scopus 로고
    • Seasonal changes in hormone-sensitive and lipoprotein lipase mRNA concentrations in marmot white adipose tissue
    • Wilson BE, Deeb S, Florant GL. Seasonal changes in hormone-sensitive and lipoprotein lipase mRNA concentrations in marmot white adipose tissue. Am J Physiol. 1992;262: R177-81.
    • (1992) Am J Physiol. , vol.262
    • Wilson, B.E.1    Deeb, S.2    Florant, G.L.3
  • 26
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 1992;69:915-26.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 27
    • 0031787025 scopus 로고    scopus 로고
    • 3-hydroxy-3-methylglutaryl-CoA lyase (HL): Gene targeting causes prenatal lethality in HL-deficient mice
    • Wang SP, Marth JD, Oligny L, et al. 3-hydroxy-3-methylglutaryl-CoA lyase (HL): gene targeting causes prenatal lethality in HL-deficient mice. Hum Mol Genet. 1998;17:2057-62.
    • (1998) Hum Mol Genet. , vol.17 , pp. 2057-2062
    • Wang, S.P.1    Marth, J.D.2    Oligny, L.3
  • 28
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem. 1987;162:156-9.
    • (1987) Anal Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 29
    • 0027520577 scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): Cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes
    • Wang S, Nadeau JH, Duncan A, et al. 3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL): cloning and characterization of a mouse liver HL cDNA and subchromosomal mapping of the human and mouse HL genes. Mamm Genome. 1993;4:382-7.
    • (1993) Mamm Genome. , vol.4 , pp. 382-387
    • Wang, S.1    Nadeau, J.H.2    Duncan, A.3
  • 30
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • Folch J, Lees M, Sloane-Stanley GH. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 1957;226:497-509.
    • (1957) J Biol Chem. , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane-Stanley, G.H.3
  • 31
    • 0028344168 scopus 로고
    • Regulation of new fat cell formation in rats: The role of dietary fats
    • Shillabeer G, Lau DC. Regulation of new fat cell formation in rats: the role of dietary fats. J Lipid Res. 1994;35:592-600.
    • (1994) J Lipid Res. , vol.35 , pp. 592-600
    • Shillabeer, G.1    Lau, D.C.2
  • 32
    • 0040381066 scopus 로고    scopus 로고
    • Leptin impairs metabolic actions of insulin in isolated rat adipocytes
    • Müller G, Ertl J, Gerl M, et al. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J Biol Chem. 1997;272:10585-93.
    • (1997) J Biol Chem. , vol.272 , pp. 10585-10593
    • Müller, G.1    Ertl, J.2    Gerl, M.3
  • 33
    • 0030763571 scopus 로고    scopus 로고
    • A simple method to predict cellular density in adipocyte metabolic incubations
    • Fine JB, Di Girolamo M. A simple method to predict cellular density in adipocyte metabolic incubations. Int J Obes Relat Metab Disord. 1997;21:764-8.
    • (1997) Int J Obes Relat Metab Disord. , vol.21 , pp. 764-768
    • Fine, J.B.1    Di Girolamo, M.2
  • 34
    • 0033773201 scopus 로고    scopus 로고
    • The hormone-sensitive lipase gene is transcribed from at least five alternative first exons in mouse adipose tissue
    • Laurin N, Wang SP, Mitchell GA. The hormone-sensitive lipase gene is transcribed from at least five alternative first exons in mouse adipose tissue. Mamm Genome. 2000;11:972-8.
    • (2000) Mamm Genome. , vol.11 , pp. 972-978
    • Laurin, N.1    Wang, S.P.2    Mitchell, G.A.3
  • 35
    • 0032528169 scopus 로고    scopus 로고
    • Emergence of brown adipocytes in white fat in mice is under genetic control
    • Guerra C, Koza RA, Yamashita H, et al. Emergence of brown adipocytes in white fat in mice is under genetic control. J Clin Invest. 1998;102:412-20.
    • (1998) J Clin Invest. , vol.102 , pp. 412-420
    • Guerra, C.1    Koza, R.A.2    Yamashita, H.3
  • 36
    • 0030876448 scopus 로고    scopus 로고
    • Regional differences in adipose tissue metabolism between sedentary and endurance-trained women
    • Mauriege P, Prud'homme D, Marcotte M, et al. Regional differences in adipose tissue metabolism between sedentary and endurance-trained women. Am J Physiol. 1997;273:497-506.
    • (1997) Am J Physiol. , vol.273 , pp. 497-506
    • Mauriege, P.1    Prud'homme, D.2    Marcotte, M.3
  • 37
    • 0016410943 scopus 로고
    • Isolation of free brown and white fat cells
    • Fain JN. Isolation of free brown and white fat cells. Methods Enzymol. 1975;35:555-61.
    • (1975) Methods Enzymol. , vol.35 , pp. 555-561
    • Fain, J.N.1
  • 38
    • 0028926192 scopus 로고
    • Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia
    • Reynisdottir S, Eriksson M, Angelin B, et al. Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia. J Clin Invest. 1995;95:2161-9.
    • (1995) J Clin Invest. , vol.95 , pp. 2161-2169
    • Reynisdottir, S.1    Eriksson, M.2    Angelin, B.3
  • 39
    • 0031796690 scopus 로고    scopus 로고
    • The putative role of the hormone-sensitive lipase gene in the pathogenesis of type II diabetes mellitus and abdominal obesity
    • Klannemark M, Orho M, Langin D, et al. The putative role of the hormone-sensitive lipase gene in the pathogenesis of type II diabetes mellitus and abdominal obesity. Diabetologia. 1998;41:1516-22.
    • (1998) Diabetologia , vol.41 , pp. 1516-1522
    • Klannemark, M.1    Orho, M.2    Langin, D.3
  • 40
    • 0033213637 scopus 로고    scopus 로고
    • PPAR γ is required for placental, cardiac, and adipose tissue development
    • Barak Y, Nelson MC, Ong ES, et al. PPAR γ is required for placental, cardiac, and adipose tissue development. Mol Cell. 1999;4:585-95.
    • (1999) Mol Cell. , vol.4 , pp. 585-595
    • Barak, Y.1    Nelson, M.C.2    Ong, E.S.3
  • 41
    • 0033212964 scopus 로고    scopus 로고
    • PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
    • Kubota N, Terauchi Y, Miki H, et al. PPARγ mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell. 1999;4:597-609.
    • (1999) Mol Cell. , vol.4 , pp. 597-609
    • Kubota, N.1    Terauchi, Y.2    Miki, H.3
  • 42
    • 0030039607 scopus 로고    scopus 로고
    • On the mechanisms of fatty acid-induced proton transport by mitochondrial uncoupling protein
    • Garlid KD, Orosz DE, Modriansky M, et al. On the mechanisms of fatty acid-induced proton transport by mitochondrial uncoupling protein. J Biol Chem. 1996;271: 2615-20.
    • (1996) J Biol Chem. , vol.271 , pp. 2615-2620
    • Garlid, K.D.1    Orosz, D.E.2    Modriansky, M.3
  • 43
    • 0033214039 scopus 로고    scopus 로고
    • The biogenetics of brown fat mitochondria from UCP1-ablated mice. UCP1 is not involved in fatty acid-induced de-energization ("uncoupling")
    • Matthias A, Jacobsson A, Cannon B, et al. The biogenetics of brown fat mitochondria from UCP1-ablated mice. UCP1 is not involved in fatty acid-induced de-energization ("uncoupling"). J Biol Chem. 1999;274:28150-60.
    • (1999) J Biol Chem. , vol.274 , pp. 28150-28160
    • Matthias, A.1    Jacobsson, A.2    Cannon, B.3
  • 44
    • 12944335303 scopus 로고    scopus 로고
    • Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity
    • Osuga JI, Ishibashi S, Oka T, et al. Targeted disruption of hormone-sensitive lipase results in male sterility and adipocyte hypertrophy, but not in obesity. Proc Natl Acad Sci USA. 2000;97:787-92.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 787-792
    • Osuga, J.I.1    Ishibashi, S.2    Oka, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.