Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells

Cancer Research

Volumn 66, Issue 11, 2006, Pages 5763-5771

  Goldkorn, Amir ^a,b   Blackburn, Elizabeth H ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MUTANT PROTEIN; RAP1 PROTEIN; RIBONUCLEOPROTEIN; RNA; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE; TELOMERIC REPEAT BINDING FACTOR 2;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CATALYSIS; CELL CYCLE ARREST; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA TEMPLATE; ENZYME ACTIVITY; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; GROWTH INHIBITION; HUMAN; HUMAN CELL; INDUCED MUTATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; RNA INTERFERENCE; TELOMERE;

ALLELES; APOPTOSIS; CATALYSIS; CELL CYCLE; CELL GROWTH PROCESSES; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; GENETIC VECTORS; HUMANS; MELANOMA; MUTATION; RETROVIRIDAE; RNA; RNA, SMALL INTERFERING; TELOMERASE; TELOMERE;

EID: 33745274487     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-3782     Document Type: Article

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